HEATR3

General Information

Gene Name       : HEATR3
Gene ID             : ENSG00000155393.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HEATR3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HEATR3ENSG00000155393.1210.4620.3915.43ENCSR000AEF
HepG2HEATR3ENSG00000155393.1214.9921.6418.32ENCSR985KAT
K562HEATR3ENSG00000155393.1211.9220.3316.12ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HEATR3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HEATR3 RNA is bound by 12 proteins.  







eCLIP assay for HEATR3 is not avaliable on ENCORE database.





12 proteins are bound to HEATR3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr165014014950140230+3'-UTR3.944503.14668HepG2LSM11
chr165013921150139329+3'-UTR3.648529.45928HepG2UPF1
chr165013923450139293+3'-UTR4.268383.18753K562AKAP1
chr165013947450139571+3'-UTR4.4753012.42188HepG2UPF1
chr165010025650100369+CDS,intron-Distal,intron-Proximal4.884436.83278K562PRPF8
chr165011790450117936+CDS3.138083.94979HepG2BCLAF1
chr165010948150109542+CDS,intron-Proximal3.966637.23562HepG2BCLAF1
chr165011290550112935+CDS,intron-Proximal5.229627.95223HepG2BCLAF1
chr165010947350109559+CDS,intron-Proximal3.108825.40232HepG2U2AF2
chr165013884950138903+CDS,intron-Proximal3.630115.97823HepG2BCLAF1
chr165010024650100358+CDS,intron-Distal,intron-Proximal3.9906410.69967HepG2PPIG
chr165010025650100367+CDS,intron-Distal,intron-Proximal3.5666818.45980HepG2BUD13
chr165010025650100344+CDS,intron-Distal,intron-Proximal3.534407.91517HepG2EFTUD2
chr165011265450112674+CDS3.469143.87469HepG2BCLAF1
chr165010959150109623+CDS,intron-Proximal4.624075.03746HepG2BCLAF1
chr165010025250100335+CDS,intron-Distal,intron-Proximal3.6332018.92504HepG2PRPF8
chr165010014250100252+CDS,intron-Proximal4.9903324.48497HepG2PRPF8
chr165010017450100256+CDS,intron-Proximal5.0240419.60589HepG2BUD13
chr165010013550100248+CDS,intron-Proximal3.000076.78476HepG2AQR
chr165011810150118132+CDS4.127123.79199HepG2PPIG
chr165010658850106624+CDS4.007555.36555HepG2BCLAF1
chr165011784550117885+CDS,intron-Proximal4.385597.09561HepG2BCLAF1
chr165013632350136347+CDS,intron-Proximal3.367074.74886HepG2BCLAF1
chr165010044150100494+CDS,intron-Distal,intron-Proximal3.5626312.21404HepG2PRPF8
chr165010012850100174+CDS3.609437.62584HepG2BUD13
chr165010272550102778+CDS3.398697.64107HepG2PPIG
chr165010603450106134+intron-Distal3.987973.20552HepG2KHSRP
chr165010018050100212+intron-Proximal4.029927.23829K562SSB
chr165010021250100225+intron-Proximal3.933186.74320K562SSB
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HEATR3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HEATR3 is not available on ENCORE database.

  • 71 RBPs can affect the levels of HEATR3.  








The Knockdown/knockout RNA-Seq assay for HEATR3 is not available on ENCORE database.





71 RBPs can affect the gene expression of HEATR3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HEATR3ENSG00000155393.81917.820801201.318800.674706.551005.77160HepG2AKAP1
HEATR3ENSG00000155393.8706.23100896.91170-0.344803.837403.07870HepG2CKAP4
HEATR3ENSG00000155393.8629.09250796.52730-0.340502.002701.40700HepG2CPSF6
HEATR3ENSG00000155393.8597.41560858.26850-0.522706.460605.50820HepG2DKC1
HEATR3ENSG00000155393.8466.86460677.69310-0.537606.946605.97900HepG2DNAJC2
HEATR3ENSG00000155393.8682.62200950.36630-0.477403.388602.73690HepG2EIF2S1
HEATR3ENSG00000155393.8825.634301050.34360-0.347301.899701.36600HepG2EIF4A3
HEATR3ENSG00000155393.8767.726901022.50980-0.413402.055801.45870HepG2EIF4B
HEATR3ENSG00000155393.81742.739101244.588200.485608.052906.76400HepG2EIF4G1
HEATR3ENSG00000155393.8338.04880476.69960-0.495803.145602.31140HepG2FUBP3
HEATR3ENSG00000155393.8452.40150690.36930-0.609805.348504.49160HepG2HNRNPA1
HEATR3ENSG00000155393.8508.34430767.87910-0.595105.232304.30150HepG2HNRNPC
HEATR3ENSG00000155393.8736.51150955.09240-0.374903.885303.04930HepG2HNRNPF
HEATR3ENSG00000155393.8772.969501149.26350-0.5722010.994209.72840HepG2HNRNPL
HEATR3ENSG00000155393.8640.64430861.68650-0.427602.891502.25040HepG2HNRNPLL
HEATR3ENSG00000155393.8521.70860762.80450-0.548107.048206.11660HepG2HNRNPU
HEATR3ENSG00000155393.8744.95100940.49620-0.336302.534201.84090HepG2IGF2BP1
HEATR3ENSG00000155393.8815.911701059.88830-0.377402.376401.76730HepG2MAGOH
HEATR3ENSG00000155393.81662.547901065.858300.641306.087805.17930HepG2MATR3
HEATR3ENSG00000155393.8491.03450680.36580-0.470504.540803.61860HepG2PPIL4
HEATR3ENSG00000155393.8747.024701194.17690-0.676808.860607.87430HepG2PUF60
HEATR3ENSG00000155393.8997.754801266.73490-0.344403.299002.56680HepG2PUM2
HEATR3ENSG00000155393.81215.50990960.365000.339802.254901.64130HepG2RBM25
HEATR3ENSG00000155393.8534.82210679.32830-0.345103.079202.40580HepG2SAFB2
HEATR3ENSG00000155393.8476.19660949.74860-0.996003.018601.59110HepG2SF1
HEATR3ENSG00000155393.8803.055201144.97130-0.511708.732407.59630HepG2SLBP
HEATR3ENSG00000155393.81314.352301534.38690-0.223302.187201.72530HepG2SRFBP1
HEATR3ENSG00000155393.81440.130301061.775300.439604.490903.92430HepG2SRSF1
HEATR3ENSG00000155393.8951.897101179.04180-0.308703.387602.70730HepG2SRSF5
HEATR3ENSG00000155393.8743.15840938.33680-0.336403.301502.55030HepG2SRSF7
HEATR3ENSG00000155393.81168.09910954.228100.291702.497701.96140HepG2TAF15
HEATR3ENSG00000155393.8553.80220741.31630-0.420703.541002.98980HepG2TIAL1
HEATR3ENSG00000155393.8572.41730747.82590-0.385603.853003.21000HepG2TRIM56
HEATR3ENSG00000155393.8388.97890281.772800.465102.511601.39220K562AARS
HEATR3ENSG00000155393.8180.47390383.96350-1.0892011.5711010.50480K562AGGF1
HEATR3ENSG00000155393.8253.62500399.52350-0.655604.100603.30300K562AKAP8L
HEATR3ENSG00000155393.8358.13260717.29800-1.002106.749705.89820K562AQR
HEATR3ENSG00000155393.8322.49080429.58890-0.413702.522201.60770K562BCLAF1
HEATR3ENSG00000155393.8261.02100385.60410-0.563003.701402.79620K562CPSF6
HEATR3ENSG00000155393.81128.73380590.503400.9346021.2220019.57750K562DDX47
HEATR3ENSG00000155393.8247.86720370.54350-0.580103.148102.17040K562EFTUD2
HEATR3ENSG00000155393.8541.04660350.331000.626905.867304.72250K562EIF3G
HEATR3ENSG00000155393.8469.99150242.983700.9517011.063309.93890K562FXR1
HEATR3ENSG00000155393.8307.01920410.53750-0.419202.457401.44660K562HNRNPA1
HEATR3ENSG00000155393.8213.74810399.43410-0.902003.757002.26500K562HNRNPA2B1
HEATR3ENSG00000155393.8131.01900308.43890-1.2352010.150509.06460K562HNRNPC
HEATR3ENSG00000155393.8239.22360454.63990-0.9264010.481008.76570K562HNRNPU
HEATR3ENSG00000155393.8221.76030343.21060-0.630103.110302.00070K562IGF2BP2
HEATR3ENSG00000155393.8306.54340424.02220-0.468002.770201.94330K562KIF1C
HEATR3ENSG00000155393.8261.09190359.36530-0.460902.494201.66710K562METAP2
HEATR3ENSG00000155393.8594.45420875.88000-0.559202.702801.58810K562MSI2
HEATR3ENSG00000155393.8347.02120458.85760-0.403003.157002.36370K562NSUN2
HEATR3ENSG00000155393.8124.51670349.51810-1.489007.911305.92980K562PABPN1
HEATR3ENSG00000155393.8228.07900390.89830-0.777305.236704.09030K562PCBP3
HEATR3ENSG00000155393.8208.27980299.84330-0.525702.427701.67960K562POLR2G
HEATR3ENSG00000155393.8469.19270350.329600.421402.789502.12240K562PTBP1
HEATR3ENSG00000155393.8241.33500396.27470-0.715504.892604.19670K562PUS1
HEATR3ENSG00000155393.8241.93930386.06270-0.674205.219404.42790K562RBM15
HEATR3ENSG00000155393.8205.93170430.01850-1.062204.577802.47430K562RBM39
HEATR3ENSG00000155393.8173.41980252.22780-0.540502.457501.52760K562RCC2
HEATR3ENSG00000155393.8519.68630367.356800.500402.888402.05210K562RPS19
HEATR3ENSG00000155393.8279.18580121.149801.204307.287505.56680K562RPS3
HEATR3ENSG00000155393.8176.60840319.71610-0.856202.660501.49050K562SF1
HEATR3ENSG00000155393.8249.39700350.11570-0.489402.209601.34970K562SF3B1
HEATR3ENSG00000155393.8196.16310285.70400-0.542503.066602.16530K562SF3B4
HEATR3ENSG00000155393.8255.33850361.37280-0.501103.104201.73280K562SSB
HEATR3ENSG00000155393.8467.74660641.51610-0.455802.659301.43940K562STAU1
HEATR3ENSG00000155393.8234.00690349.23720-0.577702.761801.74730K562SUPV3L1
HEATR3ENSG00000155393.8465.25370300.735500.629403.965002.97900K562SYNCRIP
HEATR3ENSG00000155393.8225.61980347.56730-0.623403.805502.96980K562TARDBP
HEATR3ENSG00000155393.8171.10320265.98710-0.636502.943301.97660K562TIAL1
HEATR3ENSG00000155393.8162.66720282.49590-0.796304.843203.50970K562TRIM56
HEATR3ENSG00000155393.8373.36490528.51930-0.501404.313002.72580K562TROVE2
HEATR3ENSG00000155393.8195.74380275.03680-0.490702.229801.50930K562U2AF2
HEATR3ENSG00000155393.8255.00570369.56520-0.535302.566101.59100K562UCHL5
HEATR3ENSG00000155393.8288.06140416.31630-0.531303.664302.65780K562WDR3
HEATR3ENSG00000155393.8450.89220272.500400.726403.127601.42910K562XRCC6
HEATR3ENSG00000155393.8545.20020808.19150-0.567903.231402.29090K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HEATR3 is not available on ENCORE database.





3 RBPs can affect the splicing of HEATR3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHEATR3ENSG00000155393.8chr16+5010651550106625501040885010420150109481501096220.079000.001230.03028includedHepG2SRSF1
SEHEATR3ENSG00000155393.8chr16+501065155010662550104088501042015010948150109622-0.409000.000000.00004excludedHepG2HNRNPU
MXEHEATR3ENSG00000155393.8chr16+5012861550128704501341405013428450120125501202625013616950136346-0.284000.002810.069022includedK562EFTUD2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HEATR3 is not avaliable on ENCORE database.