GTF2A2

General Information

Gene Name       : GTF2A2
Gene ID             : ENSG00000140307.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GTF2A2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GTF2A2ENSG00000140307.1068.3884.1276.25ENCSR000AEF
HepG2GTF2A2ENSG00000140307.1042.7481.3862.06ENCSR985KAT
K562GTF2A2ENSG00000140307.10107.38115.38111.38ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GTF2A2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GTF2A2 RNA is bound by 9 proteins.  







eCLIP assay for GTF2A2 is not avaliable on ENCORE database.





9 proteins are bound to GTF2A2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr155993128859931314-3'-UTR,intron-Distal,intron-Proximal3.137946.21779K562YBX3
chr155993113559931167-3'-UTR,intron-Distal4.359503.98311K562IGF2BP1
chr155994449759944514-5'-UTR,intron-Distal,intron-Proximal3.6638314.42717K562DDX3X
chr155994966559949704-5'-UTR,intron-Distal,intron-Proximal4.064046.61245HepG2DDX3X
chr155994960459949668-5'-UTR,intron-Distal3.150553.53485K562DROSHA
chr155994445159944497-5'-UTR,CDS,intron-Distal,intron-Proximal3.3802415.36654K562DDX3X
chr155994441759944485-5'-UTR,CDS,intron-Distal,intron-Proximal5.3776735.56333K562IGF2BP1
chr155994960359949709-5'-UTR,intron-Distal,intron-Proximal5.3312456.55818K562DDX3X
chr155994960259949665-5'-UTR,intron-Distal5.0316611.03866HepG2DDX3X
chr155994451459944526-5'-UTR,intron-Distal,intron-Proximal4.2653724.22040K562DDX3X
chr155994296359942973-CDS,intron-Distal,intron-Proximal5.8078142.33206K562IGF2BP1
chr155994282959942899-CDS,intron-Distal,intron-Proximal4.2254110.01959HepG2PRPF8
chr155994431859944443-CDS,intron-Distal,intron-Proximal3.099175.11245K562AQR
chr155994440359944439-CDS,intron-Distal,intron-Proximal3.060366.97761K562IGF2BP2
chr155994288259942952-CDS,intron-Distal5.5474324.21235K562IGF2BP1
chr155994295259942963-CDS,intron-Distal6.1239535.48798K562IGF2BP1
chr155994286659942918-CDS,intron-Distal,intron-Proximal3.708075.48157K562IGF2BP2
chr155993435459934442-CDS,intron-Distal,intron-Proximal3.143543.27682HepG2LARP4
chr155994440259944416-CDS,intron-Distal,intron-Proximal5.4450042.95932K562IGF2BP1
chr155994148059941605-intron-Distal4.151653.49011K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GTF2A2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GTF2A2 is not available on ENCORE database.

  • 65 RBPs can affect the levels of GTF2A2.  








The Knockdown/knockout RNA-Seq assay for GTF2A2 is not available on ENCORE database.





65 RBPs can affect the gene expression of GTF2A2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GTF2A2ENSG00000140307.6852.02340556.592200.614204.341003.69540HepG2AKAP1
GTF2A2ENSG00000140307.6455.33160365.340000.317601.970701.30890HepG2AKAP8L
GTF2A2ENSG00000140307.6555.61980431.696400.364002.044701.52450HepG2BOP1
GTF2A2ENSG00000140307.6467.81200310.531800.591102.650101.90200HepG2CNOT7
GTF2A2ENSG00000140307.6258.86390396.32050-0.614503.578802.80770HepG2CPSF6
GTF2A2ENSG00000140307.6777.50700533.186500.544103.925503.19150HepG2DDX3X
GTF2A2ENSG00000140307.6338.79180457.98690-0.434902.019801.48480HepG2DDX6
GTF2A2ENSG00000140307.6290.65480402.43280-0.469403.603502.87710HepG2DNAJC2
GTF2A2ENSG00000140307.6298.88420440.30500-0.558903.171602.53870HepG2EIF2S1
GTF2A2ENSG00000140307.6326.60080486.60390-0.575203.279102.58510HepG2EIF4A3
GTF2A2ENSG00000140307.6147.52580357.90590-1.278606.277904.44440HepG2FKBP4
GTF2A2ENSG00000140307.6239.54350397.00050-0.728902.256001.34730HepG2FTO
GTF2A2ENSG00000140307.6323.51320449.25920-0.473702.363001.76770HepG2GPKOW
GTF2A2ENSG00000140307.6333.71140455.98010-0.450402.491001.83010HepG2HNRNPC
GTF2A2ENSG00000140307.6354.27190483.77630-0.449503.634302.82130HepG2HNRNPF
GTF2A2ENSG00000140307.6386.47490573.04970-0.568306.641205.64150HepG2HNRNPL
GTF2A2ENSG00000140307.6220.27310428.73650-0.960807.741806.74920HepG2HNRNPLL
GTF2A2ENSG00000140307.6361.85640452.96650-0.324002.047601.51680HepG2HNRNPU
GTF2A2ENSG00000140307.6358.16040476.37920-0.411502.769702.04510HepG2IGF2BP1
GTF2A2ENSG00000140307.6247.70110434.41000-0.810502.846201.85000HepG2IGF2BP3
GTF2A2ENSG00000140307.6306.73020437.25750-0.511502.149701.30450HepG2MTPAP
GTF2A2ENSG00000140307.6432.73480623.76180-0.527504.277903.33000HepG2NOL12
GTF2A2ENSG00000140307.6272.84060380.15750-0.478502.268201.58900HepG2NSUN2
GTF2A2ENSG00000140307.6345.56050440.36760-0.349802.247701.69040HepG2PCBP1
GTF2A2ENSG00000140307.6253.78450404.01240-0.670805.818204.78060HepG2PPIL4
GTF2A2ENSG00000140307.6711.90900372.495100.934405.748104.75530HepG2RAVER1
GTF2A2ENSG00000140307.6337.91320464.39820-0.458703.480002.79860HepG2RECQL
GTF2A2ENSG00000140307.6486.31430358.025200.441702.315401.58030HepG2RPS2
GTF2A2ENSG00000140307.6271.91340403.39500-0.569004.759303.95340HepG2SAFB2
GTF2A2ENSG00000140307.6590.90580362.213800.706002.656501.99590HepG2SF3A3
GTF2A2ENSG00000140307.6363.42330570.83430-0.651408.060006.95820HepG2SLBP
GTF2A2ENSG00000140307.6806.31900486.947700.7275010.248009.46590HepG2SRSF1
GTF2A2ENSG00000140307.6477.63080587.83780-0.299502.262701.68960HepG2SRSF5
GTF2A2ENSG00000140307.6293.50340417.88770-0.509702.882302.14390HepG2TARDBP
GTF2A2ENSG00000140307.6310.84730440.19450-0.501903.557303.00490HepG2TIAL1
GTF2A2ENSG00000140307.6281.19010444.07270-0.659306.693905.88450HepG2TRIM56
GTF2A2ENSG00000140307.6548.06540382.145900.520103.183602.51230HepG2U2AF1
GTF2A2ENSG00000140307.6423.48370615.61390-0.539703.245202.33940HepG2UBE2L3
GTF2A2ENSG00000140307.6548.15350310.134500.8216010.169609.13550HepG2UTP3
GTF2A2ENSG00000140307.61426.870401158.841300.300103.370902.75610K562AGGF1
GTF2A2ENSG00000140307.6871.176801194.94000-0.455905.747203.72600K562BCCIP
GTF2A2ENSG00000140307.6884.786701154.72470-0.384104.736803.46150K562BCLAF1
GTF2A2ENSG00000140307.61308.188101584.70270-0.276602.455701.41690K562CPEB4
GTF2A2ENSG00000140307.6846.177901323.37890-0.645209.141607.69750K562CPSF6
GTF2A2ENSG00000140307.6686.96640876.03070-0.350703.104101.97870K562CSTF2
GTF2A2ENSG00000140307.6947.681501161.80030-0.293902.968301.71430K562DDX21
GTF2A2ENSG00000140307.61972.303401640.186800.265903.147502.45930K562DDX47
GTF2A2ENSG00000140307.61568.689201297.588700.273602.809601.92830K562DKC1
GTF2A2ENSG00000140307.6662.41680888.93500-0.424302.819001.89680K562EFTUD2
GTF2A2ENSG00000140307.61260.419101538.03700-0.287203.019302.27320K562EIF2S2
GTF2A2ENSG00000140307.61083.91280825.123300.393502.205401.48930K562EIF3G
GTF2A2ENSG00000140307.6534.02860791.97930-0.568505.280904.14700K562EIF4A3
GTF2A2ENSG00000140307.6798.214201141.30270-0.515804.262503.10490K562FTO
GTF2A2ENSG00000140307.61388.66060823.625000.7535015.1951013.88820K562FXR1
GTF2A2ENSG00000140307.6745.76430977.73480-0.390703.165502.53250K562HNRNPC
GTF2A2ENSG00000140307.6732.23840991.84580-0.437803.194901.59660K562LIN28B
GTF2A2ENSG00000140307.61442.982002454.44510-0.766304.641703.17550K562MSI2
GTF2A2ENSG00000140307.6974.512501272.44930-0.384906.067505.02220K562NSUN2
GTF2A2ENSG00000140307.61235.53900865.032100.514204.819003.83270K562PRPF8
GTF2A2ENSG00000140307.61670.350301195.888200.482004.740904.05460K562PUS1
GTF2A2ENSG00000140307.61432.080501165.175600.297502.825002.22640K562RBM15
GTF2A2ENSG00000140307.61147.79990881.247900.381202.476601.70480K562RPS19
GTF2A2ENSG00000140307.61039.605701255.59070-0.272302.289901.54240K562SF3A3
GTF2A2ENSG00000140307.6825.585801036.86040-0.328703.400202.09450K562SRSF7
GTF2A2ENSG00000140307.6626.68700837.74430-0.418802.419501.47300K562SUPV3L1
GTF2A2ENSG00000140307.61125.58520905.813600.313302.634401.83580K562SYNCRIP
GTF2A2ENSG00000140307.6815.487001104.24970-0.437302.255801.52400K562TIA1
GTF2A2ENSG00000140307.6651.38740886.54590-0.444702.988901.92330K562UCHL5
GTF2A2ENSG00000140307.61101.059901349.20540-0.293203.461702.66400K562UPF1
GTF2A2ENSG00000140307.6924.748401154.47170-0.320102.537201.69600K562WDR3
GTF2A2ENSG00000140307.61399.920801200.521400.221602.281001.50600K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GTF2A2 is not available on ENCORE database.





18 RBPs can affect the splicing of GTF2A2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.075000.002130.03847excludedK562SF3B4
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.087000.000050.00279excludedK562AKAP8L
SEGTF2A2ENSG00000140307.6chr15-599444045994452559942867599429725994960459949719-0.053000.000000.00000excludedK562AQR
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.196000.000000.00000excludedK562PUS1
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.093000.000590.01466excludedK562U2AF1
SEGTF2A2ENSG00000140307.6chr15-5994440459944525599343345993446159949604599497190.067000.000050.02746includedK562PPIL4
SEGTF2A2ENSG00000140307.6chr15-5994286759942963599343345993446159944404599444780.051000.001110.06926includedK562HNRNPUL1
SEGTF2A2ENSG00000140307.6chr15-599428675994297259934334599344615994960459949737-0.139000.000000.00003excludedK562HNRNPUL1
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.096000.000030.00217excludedK562UTP18
SEGTF2A2ENSG00000140307.6chr15-599444045994456259942867599429725994960459949719-0.053000.000880.01793excludedK562U2AF2
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.124000.000000.00004excludedK562RBM15
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.095000.000020.00133excludedK562AGGF1
SEGTF2A2ENSG00000140307.6chr15-599444045994451159942867599429725994960459949719-0.066000.000020.00226excludedK562HNRNPK
SEGTF2A2ENSG00000140307.6chr15-599444045994452559934334599344615994960459949719-0.108000.000090.07087excludedK562PABPC4
A3SSGTF2A2ENSG00000140307.6chr15-599428675994297259942867599429635994440459944511-0.068000.000370.02382shorterK562SF3B4
A3SSGTF2A2ENSG00000140307.6chr15-5993433459934573599343345993446159944404599446490.633000.000210.00175longerK562AQR
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.179000.000670.013761includedK562DROSHA
MXEGTF2A2ENSG00000140307.6chr15-5994286759942972599444045994452559934334599344615994960459949719-0.166000.000090.002902includedK562U2AF1
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.155000.000010.001371includedK562LIN28B
MXEGTF2A2ENSG00000140307.6chr15-5994286759942972599444045994452559934334599344615994960459949719-0.154000.000010.000222includedK562U2AF2
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.143000.000020.002431includedK562LARP7
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.104000.001490.065711includedK562PHF6
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.194000.000920.029951includedK562PPIL4
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.146000.005870.090191includedK562SUPV3L1
MXEGTF2A2ENSG00000140307.6chr15-59942867599429725994440459944525599343345993446159949604599497190.197000.003330.049401includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GTF2A2 is not avaliable on ENCORE database.