FBXL6

General Information

Gene Name       : FBXL6
Gene ID             : ENSG00000182325.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXL6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FBXL6ENSG00000182325.102.084.793.44ENCSR000AEF
HepG2FBXL6ENSG00000182325.1018.285.1311.71ENCSR985KAT
K562FBXL6ENSG00000182325.1014.826.7210.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXL6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXL6 RNA is bound by 11 proteins.  







eCLIP assay for FBXL6 is not avaliable on ENCORE database.





11 proteins are bound to FBXL6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8145579145145579227-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.554935.27053HepG2PPIG
chr8145581991145582169-5'-UTR,CDS,intron-Distal,intron-Proximal3.554726.23662HepG2NCBP2
chr8145579818145579875-CDS,intron-Distal,intron-Proximal3.818623.33119HepG2SRSF9
chr8145580222145580280-CDS,intron-Distal,intron-Proximal6.0804833.93413HepG2PRPF8
chr8145580750145580837-CDS,intron-Distal,intron-Proximal3.853343.43234HepG2U2AF1
chr8145580754145580838-CDS,intron-Distal,intron-Proximal3.256967.33396HepG2SF3B4
chr8145581053145581146-CDS,intron-Distal,intron-Proximal5.0788934.97257HepG2PRPF8
chr8145579959145579969-CDS,intron-Distal,intron-Proximal3.554934.13746HepG2PPIG
chr8145579840145579873-CDS,intron-Distal,intron-Proximal3.460415.30777HepG2PPIG
chr8145581045145581109-CDS,intron-Distal,intron-Proximal4.7209612.81393K562PRPF8
chr8145580767145580834-CDS,intron-Distal,intron-Proximal3.109765.48095K562PRPF8
chr8145580757145580832-CDS,intron-Distal,intron-Proximal4.6066010.07081HepG2EFTUD2
chr8145580261145580301-CDS,intron-Distal,intron-Proximal4.221196.92541HepG2PPIG
chr8145580467145580505-CDS,intron-Distal,intron-Proximal4.079806.70085HepG2PPIG
chr8145580131145580310-CDS,intron-Distal,intron-Proximal3.8447113.19358K562PRPF8
chr8145580330145580373-CDS,intron-Distal,intron-Proximal4.078586.98305HepG2PPIG
chr8145580505145580572-CDS,intron-Distal,intron-Proximal4.5058411.01413HepG2PPIG
chr8145580477145580527-CDS,intron-Distal,intron-Proximal3.560765.62957HepG2BUD13
chr8145580118145580173-CDS,intron-Distal,intron-Proximal4.049007.26626HepG2PPIG
chr8145580623145580662-CDS,intron-Distal,intron-Proximal4.348786.23016HepG2PRPF8
chr8145580748145580836-CDS,intron-Distal,intron-Proximal6.8329444.50036K562SF3B4
chr8145580769145580828-CDS,intron-Distal,intron-Proximal3.8862421.10495HepG2SF3A3
chr8145580781145580868-intron-Distal,intron-Proximal5.021208.25577K562SMNDC1
chr8145581578145581624-intron-Distal,intron-Proximal3.948323.53896K562NONO
chr8145579437145579489-intron-Distal3.994943.82050HepG2SF3B4
chr8145581236145581267-intron-Distal,intron-Proximal3.268674.22621HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXL6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXL6 is not available on ENCORE database.

  • 79 RBPs can affect the levels of FBXL6.  








The Knockdown/knockout RNA-Seq assay for FBXL6 is not available on ENCORE database.





79 RBPs can affect the gene expression of FBXL6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXL6ENSG00000182325.6431.93960306.821400.493303.793102.90860HepG2AKAP8L
FBXL6ENSG00000182325.6269.77460174.230500.630702.950502.14020HepG2ASCC1
FBXL6ENSG00000182325.6608.10700305.316900.9939016.9827015.63800HepG2CKAP4
FBXL6ENSG00000182325.6171.16020103.327800.728002.726101.71710HepG2YBX3
FBXL6ENSG00000182325.6437.33380225.109700.9580011.7925010.64320HepG2CELF1
FBXL6ENSG00000182325.6314.71890201.699000.641803.197302.53130HepG2DDX3X
FBXL6ENSG00000182325.6254.79090173.329500.555702.205301.64780HepG2DDX6
FBXL6ENSG00000182325.6163.40900101.432400.687903.035202.30390HepG2DNAJC21
FBXL6ENSG00000182325.6233.25550100.577001.2135011.055709.85010HepG2DNAJC2
FBXL6ENSG00000182325.6305.54960184.037300.731303.626202.89650HepG2EIF4A3
FBXL6ENSG00000182325.6309.67080179.246500.788702.847202.15040HepG2EIF4B
FBXL6ENSG00000182325.6409.59800185.781601.140509.826408.59500HepG2FXR1
FBXL6ENSG00000182325.6340.64650172.289400.983306.966005.93010HepG2G3BP1
FBXL6ENSG00000182325.6294.70080182.973000.687503.581702.56280HepG2G3BP2
FBXL6ENSG00000182325.6173.64050113.919600.608002.114501.49890HepG2HNRNPC
FBXL6ENSG00000182325.6463.95230174.576101.4100015.4516013.93930HepG2HNRNPK
FBXL6ENSG00000182325.6187.10690113.165400.725302.322401.76230HepG2HNRNPU
FBXL6ENSG00000182325.6287.78860175.110500.716603.854503.06960HepG2IGF2BP2
FBXL6ENSG00000182325.6297.73210164.405700.856702.426401.51300HepG2IGF2BP3
FBXL6ENSG00000182325.6363.86680176.164701.046406.748105.10690HepG2KHSRP
FBXL6ENSG00000182325.6327.66310179.651200.866904.999103.86930HepG2LARP4
FBXL6ENSG00000182325.6281.25820166.121400.759604.196302.79340HepG2LARP7
FBXL6ENSG00000182325.6474.22510185.846901.3514014.0281012.59990HepG2MAGOH
FBXL6ENSG00000182325.6551.84720186.871501.562107.156106.17580HepG2MATR3
FBXL6ENSG00000182325.6523.53660191.260701.4526016.0809014.63820HepG2NCBP2
FBXL6ENSG00000182325.6327.42930170.272000.943206.473905.38100HepG2PABPC4
FBXL6ENSG00000182325.6342.35830189.379600.854107.843406.90470HepG2PCBP1
FBXL6ENSG00000182325.6164.74920100.932200.706803.279202.48270HepG2PPIL4
FBXL6ENSG00000182325.6104.99620155.05320-0.562402.032501.36260HepG2PRPF4
FBXL6ENSG00000182325.6383.77270192.711600.9937010.512209.57870HepG2PTBP1
FBXL6ENSG00000182325.6506.61590229.073901.1450014.2058012.99640HepG2PUF60
FBXL6ENSG00000182325.6455.82810243.193500.9063012.8333011.75470HepG2PUM1
FBXL6ENSG00000182325.6462.11030243.002500.927205.765504.80930HepG2PUM2
FBXL6ENSG00000182325.6400.83120311.069300.365702.373801.79200HepG2PUS1
FBXL6ENSG00000182325.6321.18360208.688500.621903.866603.14480HepG2QKI
FBXL6ENSG00000182325.6365.99210464.17940-0.342901.984301.52630HepG2RBM22
FBXL6ENSG00000182325.6287.54130189.406900.602203.359902.62250HepG2RBM25
FBXL6ENSG00000182325.6310.51040200.323400.632202.807701.80920HepG2RBM27
FBXL6ENSG00000182325.6450.66400214.460601.0712012.3407011.35260HepG2NELFE
FBXL6ENSG00000182325.6358.94280199.757000.845407.410206.47470HepG2RECQL
FBXL6ENSG00000182325.6156.68480230.31210-0.555702.542401.88350HepG2RPLP0
FBXL6ENSG00000182325.6298.28560184.737500.691103.348402.46830HepG2RPS2
FBXL6ENSG00000182325.6341.97260188.591700.858505.205803.71700HepG2RPS5
FBXL6ENSG00000182325.6467.31360245.572400.928104.943904.02660HepG2SF3A3
FBXL6ENSG00000182325.6385.57140200.618400.942409.209108.22740HepG2SF3B4
FBXL6ENSG00000182325.6227.51080117.502600.953105.274704.43530HepG2SMN1
FBXL6ENSG00000182325.6258.96680524.25360-1.0175011.6431010.80520HepG2SRFBP1
FBXL6ENSG00000182325.6487.78590226.202901.1085016.4839015.13520HepG2SRSF5
FBXL6ENSG00000182325.6549.00370257.232901.0936014.1362012.91120HepG2SUCLG1
FBXL6ENSG00000182325.6242.28580172.950900.486202.259001.50140HepG2TIA1
FBXL6ENSG00000182325.6201.07630109.911200.871303.113202.58810HepG2TIAL1
FBXL6ENSG00000182325.6207.27550110.947600.901605.377204.64180HepG2TRIM56
FBXL6ENSG00000182325.6460.92800223.830601.0420011.622809.62900HepG2TUFM
FBXL6ENSG00000182325.6462.56250236.944300.965007.301005.91420HepG2UBE2L3
FBXL6ENSG00000182325.6262.10580149.297100.811904.149203.21900HepG2UCHL5
FBXL6ENSG00000182325.6380.13870256.487200.567504.186803.51390K562AGGF1
FBXL6ENSG00000182325.6408.98450281.852300.537003.465902.33540K562AKAP8
FBXL6ENSG00000182325.6437.37130266.889400.712502.080601.51170K562AKAP8L
FBXL6ENSG00000182325.6254.16020361.27930-0.507403.045001.45630K562CEBPZ
FBXL6ENSG00000182325.6611.15990804.76940-0.397003.418402.33280K562CELF1
FBXL6ENSG00000182325.6479.90780344.415800.478503.735102.99350K562DDX47
FBXL6ENSG00000182325.6516.95950256.814001.009203.654102.59280K562EFTUD2
FBXL6ENSG00000182325.6207.85220119.001900.804504.193303.22170K562EIF3G
FBXL6ENSG00000182325.692.49980212.54690-1.200303.667202.34250K562FKBP4
FBXL6ENSG00000182325.6395.08120257.379800.618204.757303.99250K562FXR1
FBXL6ENSG00000182325.67.7710062.36380-3.004505.617104.52940K562G3BP2
FBXL6ENSG00000182325.6162.33940244.99120-0.593702.656502.06940K562HNRNPC
FBXL6ENSG00000182325.6289.98150151.384800.937602.866401.81860K562IGF2BP2
FBXL6ENSG00000182325.6324.27800158.936601.028707.853406.40910K562MAGOH
FBXL6ENSG00000182325.6259.86040158.589400.712304.384903.19830K562MATR3
FBXL6ENSG00000182325.6427.53400317.286500.430202.915701.97550K562MBNL1
FBXL6ENSG00000182325.6513.08080697.49840-0.443003.305302.06610K562MSI2
FBXL6ENSG00000182325.6382.92540241.151600.667003.178301.61610K562NUSAP1
FBXL6ENSG00000182325.6351.78290141.384501.3150010.044208.13370K562PCBP2
FBXL6ENSG00000182325.6238.89140351.35120-0.556602.736701.90960K562PCBP3
FBXL6ENSG00000182325.6397.68580219.648400.856306.306904.85430K562PSIP1
FBXL6ENSG00000182325.6321.49480154.429001.057809.879708.68020K562PTBP1
FBXL6ENSG00000182325.6469.91350264.660700.828206.500205.70840K562PUS1
FBXL6ENSG00000182325.6341.03110257.888900.403102.187001.64950K562RBM15
FBXL6ENSG00000182325.6291.81840147.990000.979504.162003.10650K562RBM22
FBXL6ENSG00000182325.6224.85570144.330100.639502.974001.51800K562RBM34
FBXL6ENSG00000182325.6342.85420185.378300.887003.323001.97060K562SF1
FBXL6ENSG00000182325.6141.9460064.723501.132905.804604.53430K562SF3B4
FBXL6ENSG00000182325.6379.09180226.116700.745402.900001.55110K562SFPQ
FBXL6ENSG00000182325.651.32160109.27600-1.090304.076502.04440K562SND1
FBXL6ENSG00000182325.6132.5429071.518800.890003.008501.89890K562SRSF4
FBXL6ENSG00000182325.6247.15400143.040800.788904.260902.91340K562SRSF5
FBXL6ENSG00000182325.619.7899061.20710-1.628902.851901.36330K562TAF15
FBXL6ENSG00000182325.6469.69830153.197601.6162021.6545019.27730K562TARDBP
FBXL6ENSG00000182325.6323.90570147.786801.1320010.211308.51970K562TIA1
FBXL6ENSG00000182325.6284.87010145.116000.973006.742904.85610K562TRA2A
FBXL6ENSG00000182325.6315.45420224.385300.491402.518601.62290K562TRIM56
FBXL6ENSG00000182325.6251.06570387.58130-0.626404.380703.27030K562WDR3
FBXL6ENSG00000182325.6484.91710806.55260-0.734003.652502.63480K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXL6 is not available on ENCORE database.





16 RBPs can affect the splicing of FBXL6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXL6ENSG00000182325.6chr8-145581098145581162145580649145580781145581287145581446-0.219000.005830.05270excludedK562AQR
A3SSFBXL6ENSG00000182325.6chr8-145580649145581162145580649145580803145581287145582889-0.100000.002450.01544shorterK562AQR
RIFBXL6ENSG00000182325.6chr8-145580649145581162145580649145580781145581098145581162-0.286000.000080.00658excludedHepG2AKAP1
RIFBXL6ENSG00000182325.6chr8-145580649145581162145580649145580781145581098145581162-0.321000.000050.00646excludedHepG2DDX6
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.230000.003180.02096includedK562PUS1
RIFBXL6ENSG00000182325.6chr8-1455803401455805141455803401455803731455804671455805140.103000.007250.04269includedK562PUS1
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.271000.011230.06213includedK562PUS1
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.288000.007730.07020includedHepG2SF3A3
RIFBXL6ENSG00000182325.6chr8-145580649145581162145580649145580781145581098145581162-0.294000.000020.00118excludedHepG2MATR3
RIFBXL6ENSG00000182325.6chr8-145579959145580373145579959145580191145580259145580373-0.505000.003180.06406excludedHepG2FTO
RIFBXL6ENSG00000182325.6chr8-145580649145581162145580649145580781145581098145581162-0.176000.000800.02108excludedHepG2SRSF1
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.323000.009310.07324includedHepG2TAF15
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.246000.005460.04750includedHepG2TAF15
RIFBXL6ENSG00000182325.6chr8-1455803401455805141455803401455803731455804671455805140.202000.002000.02093includedHepG2U2AF1
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.239000.005360.05125includedK562RBM15
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.287000.008540.05435includedHepG2SF3B4
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.433000.000010.00017includedHepG2SF3B4
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.383000.005850.07703includedHepG2FUBP3
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.234000.000650.00878includedHepG2RBM22
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.264000.011940.09170includedK562EFTUD2
RIFBXL6ENSG00000182325.6chr8-1455806491455811621455806491455807811455810981455811620.307000.000020.00035includedK562EFTUD2
RIFBXL6ENSG00000182325.6chr8-1455799591455803731455799591455801911455802591455803730.262000.000580.00412includedK562AQR
RIFBXL6ENSG00000182325.6chr8-1455803401455805141455803401455803731455804671455805140.086000.000060.00054includedK562AQR
MXEFBXL6ENSG00000182325.6chr8-1455806491455807811455810981455811621455804671455805751455812871455814460.239000.000470.044981includedK562PUM1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXL6 is not avaliable on ENCORE database.