EXOSC10

General Information

Gene Name : EXOSC10
Gene ID : ENSG00000171824.13
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: EXOSC10)

Not Available

Antibody Validation

Bethyl Labs: A303-987A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	EXOSC10	ENSG00000171824.13	47.72	53.70	50.71	ENCSR000AEF
HepG2	EXOSC10	ENSG00000171824.13	57.37	63.24	60.30	ENCSR985KAT
K562	EXOSC10	ENSG00000171824.13	87.59	98.22	92.91	ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
eCLIP	eCLIP: 4161	ENCSR521GON	EXOSC10	K562	Released	ENCAB270KRD	ENCSR481MVN
knockdown followed by RNA-seq	EXOSC10-BGKcLV21-K562	ENCSR299PRA	EXOSC10	K562	Released		ENCSR854OFV	CRISPR	KD% = 60.5,65.1389045
knockdown followed by RNA-seq	EXOSC10-BGHcLV22-HepG2	ENCSR455KXW	EXOSC10	HepG2	Released		ENCSR704VPL	CRISPR	KD% = 83.1,86.7

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
EXOSC10	4161	K562	ENCSR521GON	ENCSR481MVN	ENCAB270KRD	A303-987A	1	Released	ENCODE4

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
EXOSC10	ENCAB270KRD	A303-987A	1			Released, ENCODE4	BGHcLV22-23, Released, ENCODE4	BGKcLV21-21, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
EXOSC10	K562	CRISPR	ENCSR299PRA	ENCSR854OFV	EXOSC10-BGKcLV21-21,EXOSC10-BGKcLV21-22	NT-BGKcLV21-1,NT-BGKcLV21-2	60.5,65.1389045	Released	ENCODE4
EXOSC10	HepG2	CRISPR	ENCSR455KXW	ENCSR704VPL	EXOSC10-BGHcLV22-23,EXOSC10-BGHcLV22-24	NT-BGHcLV22-1,NT-BGHcLV22-2	83.1,86.7	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
EXOSC10	Product_ID: A303-987A Lot_ID: 1 Source: Bethyl Labs Target Name: EXOSC10-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for EXOSC10 is not avaliable on ENCORE database.

Proteins bound to RNA

EXOSC10 RNA is bound by 21 proteins.

eCLIP assay for EXOSC10 is not avaliable on ENCORE database.

21 proteins are bound to EXOSC10 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr1	11128052	11128141	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.77353	4.34551	K562	ZC3H11A
chr1	11136902	11136998	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.71279	11.70905	HepG2	GRWD1
chr1	11133997	11134056	-	3'-UTR,CDS,intron-Distal	3.03569	3.17635	HepG2	PPIG
chr1	11151549	11151652	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.45869	29.81534	K562	DDX24
chr1	11151561	11151651	-	3'-UTR,CDS,intron-Distal	3.79902	9.84695	HepG2	GRWD1
chr1	11134359	11134382	-	3'-UTR,CDS,intron-Distal	3.45060	9.00464	K562	ZNF622
chr1	11128071	11128136	-	3'-UTR,CDS,intron-Distal	3.12351	3.07541	K562	GRWD1
chr1	11132186	11132227	-	3'-UTR,CDS,intron-Distal	3.24278	5.51984	K562	UCHL5
chr1	11151549	11151596	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.71186	9.01874	HepG2	BCLAF1
chr1	11129646	11129692	-	3'-UTR,CDS,intron-Distal	4.16831	9.16086	K562	UCHL5
chr1	11132152	11132165	-	3'-UTR,CDS,intron-Distal	3.56538	5.35144	K562	ZNF622
chr1	11132171	11132214	-	3'-UTR,CDS,intron-Distal	3.42698	10.46214	K562	ZNF622
chr1	11134368	11134384	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.01001	3.29348	K562	YBX3
chr1	11134336	11134357	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.17081	4.61143	K562	UCHL5
chr1	11136898	11136955	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.02243	5.29017	HepG2	BCLAF1
chr1	11137364	11137410	-	3'-UTR,intron-Distal,intron-Proximal	3.37839	3.88924	K562	PRPF8
chr1	11137389	11137427	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.05630	5.61068	HepG2	PRPF8
chr1	11129659	11129682	-	3'-UTR,CDS,intron-Distal	3.27921	6.21602	K562	ZNF622
chr1	11126756	11126791	-	3'-UTR,CDS,intron-Distal	4.51287	4.78529	HepG2	BCLAF1
chr1	11128705	11128730	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.38441	3.05161	HepG2	PPIG
chr1	11132143	11132179	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.07073	7.44737	K562	DDX24
chr1	11136899	11136978	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.32295	13.81366	HepG2	PPIG
chr1	11134001	11134013	-	3'-UTR,CDS,intron-Distal	3.42608	6.21602	K562	ZNF622
chr1	11128024	11128070	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.16263	4.77826	K562	AQR
chr1	11126702	11126760	-	3'-UTR,intron-Distal,intron-Proximal	6.40127	17.51182	K562	PUM2
chr1	11132214	11132226	-	3'-UTR,CDS,intron-Distal	3.18367	7.02016	K562	ZNF622
chr1	11151556	11151632	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.46513	25.42358	K562	ZNF622
chr1	11129613	11129718	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.66034	7.16941	HepG2	PABPN1
chr1	11134346	11134368	-	3'-UTR,CDS,intron-Distal	3.16185	4.08171	K562	YBX3
chr1	11134336	11134359	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.69793	8.21285	K562	ZNF622
chr1	11134023	11134063	-	3'-UTR,CDS,intron-Distal	3.27770	4.06531	HepG2	GRWD1
chr1	11140882	11140953	-	CDS,intron-Distal,intron-Proximal	3.30798	7.65887	HepG2	GRWD1
chr1	11147469	11147533	-	CDS,intron-Distal,intron-Proximal	4.90652	13.70516	HepG2	PRPF8
chr1	11147497	11147632	-	CDS,intron-Distal,intron-Proximal	3.44025	13.43977	HepG2	GRWD1
chr1	11148182	11148226	-	CDS,intron-Distal	4.51552	8.51520	K562	DDX24
chr1	11137658	11137707	-	CDS,intron-Distal	3.07580	12.09972	K562	ZNF622
chr1	11140896	11140965	-	CDS,intron-Distal,intron-Proximal	3.69690	19.93487	K562	ZNF622
chr1	11147502	11147552	-	CDS,intron-Distal,intron-Proximal	3.43971	17.69919	K562	ZNF622
chr1	11147467	11147523	-	CDS,intron-Distal,intron-Proximal	3.91315	10.55329	K562	PRPF8
chr1	11137652	11137750	-	CDS,intron-Distal,intron-Proximal	3.57172	21.61549	K562	EFTUD2
chr1	11137578	11137652	-	CDS,intron-Distal,intron-Proximal	4.56358	13.59059	K562	EFTUD2
chr1	11137595	11137648	-	CDS,intron-Distal,intron-Proximal	3.81253	5.18845	HepG2	U2AF2
chr1	11140783	11140857	-	CDS,intron-Distal,intron-Proximal	4.86499	13.44390	HepG2	PRPF8
chr1	11140534	11140612	-	CDS,intron-Distal,intron-Proximal	3.20797	11.92838	K562	PRPF8
chr1	11140807	11140888	-	CDS,intron-Distal,intron-Proximal	3.08511	4.83253	K562	GRWD1
chr1	11137697	11137708	-	CDS,intron-Distal	3.20857	6.24896	HepG2	PPIG
chr1	11158161	11158210	-	CDS,intron-Distal	3.48590	11.15182	K562	ZNF622
chr1	11150675	11150725	-	CDS,intron-Distal	3.84411	11.81690	K562	DDX24
chr1	11141250	11141296	-	CDS,intron-Distal,intron-Proximal	4.57749	5.64460	HepG2	GRWD1
chr1	11158175	11158209	-	CDS,intron-Distal	3.08471	4.14020	K562	BUD13
chr1	11137592	11137645	-	CDS,intron-Distal,intron-Proximal	3.27720	4.11767	K562	U2AF2
chr1	11137603	11137621	-	CDS,intron-Distal,intron-Proximal	3.64847	3.99381	K562	BUD13
chr1	11140885	11140960	-	CDS,intron-Distal,intron-Proximal	3.17350	3.52390	K562	MTPAP
chr1	11151069	11151106	-	CDS,intron-Distal,intron-Proximal	3.23321	6.25518	K562	DDX24
chr1	11139729	11139794	-	CDS,intron-Distal,intron-Proximal	3.34789	6.92749	HepG2	PRPF8
chr1	11139766	11139793	-	CDS,intron-Distal,intron-Proximal	3.97658	5.58370	HepG2	PPIG
chr1	11158076	11158129	-	CDS,intron-Distal,intron-Proximal	3.09941	4.79538	HepG2	BCLAF1
chr1	11151053	11151072	-	CDS,intron-Distal,intron-Proximal	4.45984	5.26367	K562	AQR
chr1	11140527	11140615	-	CDS,intron-Distal,intron-Proximal	3.36334	18.58147	K562	EFTUD2
chr1	11142748	11142757	-	CDS,intron-Distal,intron-Proximal	3.96061	3.38114	HepG2	GRWD1
chr1	11137506	11137549	-	CDS,intron-Distal,intron-Proximal	5.50144	6.39134	HepG2	SF3A3
chr1	11155814	11155865	-	CDS,intron-Distal,intron-Proximal	4.23044	15.15889	K562	ZNF622
chr1	11147508	11147598	-	CDS,intron-Distal	3.86397	4.06874	HepG2	UCHL5
chr1	11147518	11147566	-	CDS,intron-Distal	3.36419	7.98451	K562	DDX24
chr1	11150695	11150758	-	CDS,intron-Distal,intron-Proximal	3.19384	5.62171	K562	AQR
chr1	11137652	11137697	-	CDS,intron-Distal,intron-Proximal	3.02595	7.18270	HepG2	PPIG
chr1	11150688	11150726	-	CDS,intron-Distal,intron-Proximal	3.14673	10.62064	K562	ZNF622
chr1	11137636	11137725	-	CDS,intron-Distal,intron-Proximal	3.37421	3.36034	K562	SRSF1
chr1	11140816	11140849	-	CDS,intron-Distal,intron-Proximal	3.04826	5.01560	K562	UCHL5
chr1	11141099	11141161	-	CDS,intron-Distal,intron-Proximal	3.92478	5.13777	HepG2	PRPF8
chr1	11150615	11150658	-	CDS,intron-Distal	3.93806	9.20662	K562	DDX24
chr1	11140888	11140961	-	CDS,intron-Distal,intron-Proximal	3.38754	6.93772	K562	GRWD1
chr1	11139767	11139778	-	CDS,intron-Distal,intron-Proximal	3.44217	7.70405	K562	ZNF622
chr1	11150630	11150688	-	CDS,intron-Distal	3.20549	7.99242	K562	ZNF622
chr1	11137593	11137641	-	CDS,intron-Distal,intron-Proximal	3.57251	6.65114	HepG2	PRPF8
chr1	11155888	11155933	-	CDS,intron-Distal	3.46914	5.76104	HepG2	BCLAF1
chr1	11158079	11158134	-	CDS,intron-Distal	4.51141	12.73172	K562	DDX24
chr1	11140645	11140733	-	intron-Distal,intron-Proximal	3.27841	3.44195	K562	TARDBP
chr1	11138681	11138791	-	intron-Distal	4.05879	4.07991	K562	ILF3
chr1	11151027	11151053	-	intron-Distal,intron-Proximal	5.55262	6.44303	K562	AQR
chr1	11140435	11140483	-	intron-Distal,intron-Proximal	4.13142	10.09732	K562	PRPF8
chr1	11140810	11140821	-	intron-Distal,intron-Proximal	3.56086	3.04392	K562	AQR
chr1	11140447	11140476	-	intron-Distal,intron-Proximal	3.55081	3.69252	K562	EFTUD2
chr1	11131037	11131084	-	intron-Distal,intron-Proximal	3.79891	4.22551	K562	SF3B4
chr1	11140778	11140810	-	intron-Distal,intron-Proximal	4.41611	4.98250	K562	AQR
chr1	11140483	11140534	-	intron-Distal,intron-Proximal	4.49218	13.91938	K562	PRPF8
chr1	11129570	11129592	-	intron-Distal,intron-Proximal	5.76117	8.34710	K562	AQR
chr1	11142345	11142463	-	intron-Distal	5.79144	16.01960	K562	TARDBP
chr1	11137709	11137758	-	intron-Distal,intron-Proximal	3.94565	20.69951	K562	SF3B4
chr1	11159734	11159777	-	intron-Distal	4.84602	4.86944	K562	AQR
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for EXOSC10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for EXOSC10 is not available on ENCORE database.
63 RBPs can affect the levels of EXOSC10.

The Knockdown/knockout RNA-Seq assay for EXOSC10 is not available on ENCORE database.

63 RBPs can affect the gene expression of EXOSC10 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
EXOSC10	ENSG00000171824.9	1895.75350	1466.48020	0.37030	6.26810	5.42870	HepG2	ACO1
EXOSC10	ENSG00000171824.9	1767.80950	2144.54140	-0.27870	3.65760	2.88780	HepG2	AUH
EXOSC10	ENSG00000171824.9	853.30540	1228.44310	-0.52570	4.14650	3.06560	HepG2	BCLAF1
EXOSC10	ENSG00000171824.9	1119.25880	2046.50850	-0.87060	15.13970	13.89480	HepG2	BOP1
EXOSC10	ENSG00000171824.9	1356.25170	1770.30650	-0.38440	4.41280	3.46610	HepG2	CALR
EXOSC10	ENSG00000171824.9	1721.25980	2413.89050	-0.48790	3.50620	2.39650	HepG2	CCAR1
EXOSC10	ENSG00000171824.9	1538.56140	1878.79630	-0.28820	1.93420	1.34840	HepG2	CPSF6
EXOSC10	ENSG00000171824.9	1046.54310	1362.19570	-0.38030	3.26530	2.53130	HepG2	DDX21
EXOSC10	ENSG00000171824.9	905.99610	1249.33750	-0.46360	3.56150	2.86220	HepG2	DDX3X
EXOSC10	ENSG00000171824.9	1006.06360	1288.78160	-0.35730	4.00050	3.16850	HepG2	DNAJC21
EXOSC10	ENSG00000171824.9	906.00700	1277.38480	-0.49560	9.37940	8.26400	HepG2	DNAJC2
EXOSC10	ENSG00000171824.9	1300.63060	1988.98790	-0.61280	7.51490	6.20020	HepG2	EIF4G2
EXOSC10	ENSG00000171824.9	2151.06690	2462.28750	-0.19490	2.01700	1.48580	HepG2	ETF1
EXOSC10	ENSG00000171824.9	891.54960	1157.01410	-0.37600	2.57310	1.34520	HepG2	FKBP4
EXOSC10	ENSG00000171824.9	1265.37220	869.37190	0.54140	5.73050	4.61100	HepG2	FUBP3
EXOSC10	ENSG00000171824.9	1632.56280	1150.51990	0.50480	4.49170	3.62500	HepG2	FXR1
EXOSC10	ENSG00000171824.9	1491.70600	1133.08170	0.39660	2.99510	2.06840	HepG2	G3BP2
EXOSC10	ENSG00000171824.9	1364.91840	2129.73460	-0.64190	6.76120	5.78740	HepG2	GPKOW
EXOSC10	ENSG00000171824.9	1046.55710	1301.12830	-0.31410	2.33600	1.73780	HepG2	HNRNPA1
EXOSC10	ENSG00000171824.9	1577.13580	1934.18950	-0.29440	3.52660	2.49000	HepG2	HNRNPA2B1
EXOSC10	ENSG00000171824.9	1057.16720	1447.25920	-0.45310	4.33900	3.48570	HepG2	HNRNPC
EXOSC10	ENSG00000171824.9	1583.10130	2012.93210	-0.34650	3.68830	2.87020	HepG2	HNRNPF
EXOSC10	ENSG00000171824.9	1733.16620	1080.88340	0.68110	8.64520	7.46340	HepG2	HNRNPK
EXOSC10	ENSG00000171824.9	1640.54830	1917.09910	-0.22470	3.02460	2.32230	HepG2	HNRNPL
EXOSC10	ENSG00000171824.9	1398.93250	2032.44740	-0.53890	5.65470	4.78850	HepG2	HNRNPLL
EXOSC10	ENSG00000171824.9	1567.25890	1982.13830	-0.33880	2.96440	2.21730	HepG2	IGF2BP1
EXOSC10	ENSG00000171824.9	1491.69380	1157.32450	0.36610	2.26620	1.69130	HepG2	MATR3
EXOSC10	ENSG00000171824.9	1376.07520	1730.18360	-0.33040	2.97560	2.13750	HepG2	MSI2
EXOSC10	ENSG00000171824.9	1362.63290	1802.17320	-0.40330	3.56810	2.71890	HepG2	NSUN2
EXOSC10	ENSG00000171824.9	739.31420	1021.37550	-0.46630	2.05750	1.30810	HepG2	PABPC1
EXOSC10	ENSG00000171824.9	1536.03720	1992.13980	-0.37510	3.69320	3.01570	HepG2	PUF60
EXOSC10	ENSG00000171824.9	1879.97920	2114.75760	-0.16980	1.91320	1.40050	HepG2	PUM1
EXOSC10	ENSG00000171824.9	1027.76810	1493.70900	-0.53940	10.84810	9.76480	HepG2	PUS1
EXOSC10	ENSG00000171824.9	1490.31500	1274.76740	0.22530	2.11000	1.62470	HepG2	NELFE
EXOSC10	ENSG00000171824.9	1576.00280	1187.32050	0.40850	6.09020	5.22470	HepG2	RECQL
EXOSC10	ENSG00000171824.9	1542.51750	2168.79810	-0.49160	4.73620	3.87460	HepG2	RPLP0
EXOSC10	ENSG00000171824.9	2926.95700	2114.83780	0.46880	2.80750	2.12890	HepG2	SF3A3
EXOSC10	ENSG00000171824.9	1491.56310	1192.52110	0.32270	3.93820	3.25330	HepG2	SF3B4
EXOSC10	ENSG00000171824.9	1588.56780	2238.38100	-0.49470	2.86520	2.06960	HepG2	SNRNP70
EXOSC10	ENSG00000171824.9	1757.31450	1244.75710	0.49740	9.33210	8.57870	HepG2	SRSF1
EXOSC10	ENSG00000171824.9	1316.92270	1977.72630	-0.58670	7.78560	6.71570	HepG2	SRSF7
EXOSC10	ENSG00000171824.9	1276.17820	1012.69620	0.33350	4.25450	3.59790	HepG2	SRSF9
EXOSC10	ENSG00000171824.9	1353.39910	1118.90080	0.27440	2.63850	2.08960	HepG2	TAF15
EXOSC10	ENSG00000171824.9	1294.94880	1981.07960	-0.61340	7.78070	6.64440	HepG2	TARDBP
EXOSC10	ENSG00000171824.9	687.14990	927.47540	-0.43270	3.17240	2.10980	HepG2	TFIP11
EXOSC10	ENSG00000171824.9	1366.13670	1875.53270	-0.45720	8.81400	7.68650	HepG2	UPF1
EXOSC10	ENSG00000171824.9	3467.06450	2541.83050	0.44770	5.54890	3.80740	K562	AARS
EXOSC10	ENSG00000171824.9	3452.46910	4384.92330	-0.34490	3.52730	2.88070	K562	AQR
EXOSC10	ENSG00000171824.9	2350.48910	2689.07320	-0.19410	2.42090	1.52440	K562	BCLAF1
EXOSC10	ENSG00000171824.9	3001.96310	3674.77410	-0.29170	2.33390	1.53920	K562	BOP1
EXOSC10	ENSG00000171824.9	3106.75370	3907.20300	-0.33070	3.83510	2.91240	K562	CPSF6
EXOSC10	ENSG00000171824.9	5463.80500	4834.46580	0.17640	2.15520	1.56840	K562	DDX47
EXOSC10	ENSG00000171824.9	3293.51280	3915.75240	-0.24970	3.18080	2.41790	K562	EIF2S2
EXOSC10	ENSG00000171824.9	2673.24440	1968.86580	0.44110	7.56240	6.25370	K562	EIF3G
EXOSC10	ENSG00000171824.9	3165.99140	3975.75020	-0.32860	3.05970	2.15600	K562	FMR1
EXOSC10	ENSG00000171824.9	2754.71220	3369.92140	-0.29080	2.14780	1.34690	K562	FTO
EXOSC10	ENSG00000171824.9	3224.98830	2257.00630	0.51480	11.07510	9.95000	K562	FXR1
EXOSC10	ENSG00000171824.9	2745.72210	3730.30830	-0.44210	5.52300	4.40640	K562	GPKOW
EXOSC10	ENSG00000171824.9	3640.53760	5218.23380	-0.51940	8.32270	6.99960	K562	GRSF1
EXOSC10	ENSG00000171824.9	3905.43020	5583.78960	-0.51580	6.56010	5.34890	K562	HSPD1
EXOSC10	ENSG00000171824.9	3043.96610	3641.24320	-0.25850	2.26830	1.47680	K562	METAP2
EXOSC10	ENSG00000171824.9	2466.43870	2950.24770	-0.25840	2.58640	1.81580	K562	POLR2G
EXOSC10	ENSG00000171824.9	3527.29780	4674.83250	-0.40640	4.33350	3.27570	K562	PPIG
EXOSC10	ENSG00000171824.9	5633.89740	6744.46530	-0.25960	3.48090	2.40450	K562	PUM2
EXOSC10	ENSG00000171824.9	4430.40630	2858.39790	0.63210	2.56850	1.40220	K562	SNRNP200
EXOSC10	ENSG00000171824.9	3204.79280	2482.86610	0.36810	4.45840	3.56420	K562	SRSF1
EXOSC10	ENSG00000171824.9	1881.63660	2295.55360	-0.28690	2.55480	1.55030	K562	SRSF4
EXOSC10	ENSG00000171824.9	2979.37530	3698.03420	-0.31170	4.93300	3.35290	K562	SRSF7
EXOSC10	ENSG00000171824.9	3846.49560	2959.12790	0.37830	5.24280	4.10350	K562	SYNCRIP
EXOSC10	ENSG00000171824.9	1773.71300	2512.66960	-0.50240	5.47820	4.46550	K562	TARDBP
EXOSC10	ENSG00000171824.9	1476.85430	1930.96450	-0.38680	2.81650	1.71250	K562	U2AF1
EXOSC10	ENSG00000171824.9	3673.59420	4384.72070	-0.25530	2.82080	2.09540	K562	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for EXOSC10 is not available on ENCORE database.

20 RBPs can affect the splicing of EXOSC10 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	EXOSC10	ENSG00000171824.9	chr1	-	11140555	11140606			11139767	11139879	11140820	11140969	-0.13600	0.00001	0.00033	excluded	K562	SF3B4
SE	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11139879			11136898	11137708	11140555	11140606	-0.06400	0.00008	0.00516	excluded	K562	PRPF8
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137386	11137500			11136898	11137005	11137657	11137708	-0.08000	0.00317	0.08763	excluded	K562	PRPF8
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.11200	0.00004	0.02773	excluded	K562	SMNDC1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137421	11137500			11136898	11137005	11137657	11137708	-0.07700	0.00008	0.00407	excluded	K562	AKAP8L
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.21600	0.00000	0.00000	excluded	K562	AKAP8L
SE	EXOSC10	ENSG00000171824.9	chr1	-	11140555	11140571			11139767	11139879	11140820	11141043	-0.20600	0.00011	0.00186	excluded	K562	AQR
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.07500	0.00006	0.00102	excluded	K562	AQR
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137421	11137500			11136898	11137005	11137657	11137708	-0.05800	0.00005	0.00092	excluded	K562	AQR
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142825			11141138	11141295	11147504	11147648	0.09500	0.00062	0.02676	included	K562	FXR1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137386	11137500			11136898	11137005	11137657	11137708	0.05900	0.00254	0.07959	included	K562	FXR1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137421	11137500			11136898	11137005	11137657	11137708	-0.10500	0.00000	0.00012	excluded	K562	PUS1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.25400	0.00000	0.00000	excluded	K562	PUS1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11139879			11136898	11137708	11140555	11140606	-0.05800	0.00016	0.01258	excluded	K562	EFTUD2
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137421	11137523			11136898	11137005	11137657	11137708	-0.09900	0.00134	0.06342	excluded	K562	EFTUD2
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.15600	0.00000	0.01241	excluded	K562	DDX6
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142825			11141138	11141295	11147504	11147634	-0.18600	0.00040	0.08450	excluded	K562	PPIL4
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.10000	0.00009	0.07948	excluded	K562	ZRANB2
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142851			11141138	11141295	11147504	11147709	-0.10100	0.00078	0.09948	excluded	K562	SRSF7
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.24600	0.00000	0.00000	excluded	K562	UTP18
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11141138	11141295	11147504	11147634	0.44500	0.00001	0.00029	included	K562	U2AF2
SE	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11139879			11136898	11137708	11140555	11140606	-0.12300	0.00161	0.02942	excluded	K562	U2AF2
SE	EXOSC10	ENSG00000171824.9	chr1	-	11137421	11137500			11136898	11137005	11137657	11137708	-0.06100	0.00064	0.01939	excluded	K562	RBM15
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.28600	0.00000	0.00000	excluded	K562	RBM15
SE	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142935			11141138	11141295	11147504	11147648	-0.30600	0.00000	0.00000	excluded	K562	AGGF1
SE	EXOSC10	ENSG00000171824.9	chr1	-	11140555	11140606			11139767	11139879	11140820	11140969	-0.07900	0.00005	0.00350	excluded	K562	SF3B1
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11133990	11134110			11133990	11134065	11134287	11134409	0.07200	0.00001	0.00038	longer	K562	U2AF2
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11133990	11134110			11133990	11134065	11134287	11134383	0.18600	0.00000	0.00005	longer	HepG2	U2AF2
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11130956	11131045			11130956	11131030	11132143	11132228	-0.08700	0.00115	0.02992	shorter	HepG2	U2AF2
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11130956	11131112			11130956	11131030	11132143	11132286	0.13900	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11126677	11126884			11126677	11126805	11128064	11128208	0.05500	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11128701	11128788			11128701	11128763	11129615	11129787	0.07100	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11151070	11151274			11151070	11151236	11151549	11151672	0.05800	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11129615	11129864			11129615	11129787	11130956	11131052	0.08700	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11140013			11139767	11139879	11140555	11140606	0.05900	0.00063	0.00460	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11148179	11148333			11148179	11148255	11150610	11150775	0.06400	0.00000	0.00000	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11136898	11137059			11136898	11137005	11137421	11137500	0.08900	0.00002	0.00023	longer	K562	AQR
A3SS	EXOSC10	ENSG00000171824.9	chr1	-	11142744	11142851			11142744	11142825	11147504	11147735	-0.27800	0.00097	0.00673	shorter	K562	AQR
A5SS	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11142744	11142825	11141138	11141295	0.05300	0.00008	0.00219	longer	K562	AQR
A5SS	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11142744	11142825	11141138	11141295	0.06300	0.00000	0.00000	longer	K562	AGGF1
A5SS	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11142744	11142825	11141138	11141295	0.07100	0.00000	0.00000	longer	K562	RBM15
A5SS	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11142744	11142825	11141138	11141295	0.15100	0.00000	0.00000	longer	K562	U2AF2
A5SS	EXOSC10	ENSG00000171824.9	chr1	-	11142590	11142825			11142744	11142825	11141138	11141295	0.08100	0.00000	0.00000	longer	K562	AKAP8L
RI	EXOSC10	ENSG00000171824.9	chr1	-	11136898	11137708			11136898	11137005	11137657	11137708	-0.12700	0.01389	0.07195	excluded	K562	AQR
RI	EXOSC10	ENSG00000171824.9	chr1	-	11136898	11137708			11136898	11137005	11137657	11137708	0.31700	0.00010	0.01536	included	K562	LARP4
MXE	EXOSC10	ENSG00000171824.9	chr1	-	11137657	11137708	11140820	11140969	11136898	11137005	11141138	11141295	-0.07500	0.00192	0.03389	2included	K562	PUS1
MXE	EXOSC10	ENSG00000171824.9	chr1	-	11137657	11137708	11140555	11140606	11136898	11137005	11140820	11140969	-0.08700	0.00092	0.01901	2included	K562	PUS1
MXE	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11139879	11140555	11140606	11136898	11137708	11140820	11140969	0.23400	0.00076	0.03245	1included	K562	TAF15
MXE	EXOSC10	ENSG00000171824.9	chr1	-	11139767	11139879	11140555	11140606	11136898	11137708	11140820	11140969	0.30600	0.00065	0.02098	1included	K562	FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

EXOSC10

General Information

Functions

Localization

Domains (AlphaFold: EXOSC10)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for EXOSC10 is not avaliable on ENCORE database.

21 proteins are bound to EXOSC10 RNA:

eCLIP assay for EXOSC10 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for EXOSC10 is not available on ENCORE database.

63 RBPs can affect the gene expression of EXOSC10 :

The Knockdown/knockout RNA-Seq assay for EXOSC10 is not available on ENCORE database.

20 RBPs can affect the splicing of EXOSC10 :

The Knockdown/knockout RNA-Seq assay for EXOSC10 is not avaliable on ENCORE database.