COPS4

General Information

Gene Name       : COPS4
Gene ID             : ENSG00000138663.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COPS4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COPS4ENSG00000138663.860.2050.2055.20ENCSR000AEF
HepG2COPS4ENSG00000138663.824.3034.9129.60ENCSR985KAT
K562COPS4ENSG00000138663.859.7355.4357.58ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COPS4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COPS4 RNA is bound by 6 proteins.  







eCLIP assay for COPS4 is not avaliable on ENCORE database.





6 proteins are bound to COPS4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr48399687483996920+3'-UTR6.0937916.50046K562PABPC4
chr48399682483996911+3'-UTR5.0147012.08812K562LIN28B
chr48398766183987706+CDS3.576883.01531K562YBX3
chr48397852783978562+CDS,intron-Proximal3.984843.46958K562YBX3
chr48397811483978198+CDS3.310873.43213K562UCHL5
chr48397808783978203+CDS3.824693.11282HepG2G3BP1
chr48396597683966082+intron-Distal4.328093.83958HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COPS4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COPS4 is not available on ENCORE database.

  • 77 RBPs can affect the levels of COPS4.  








The Knockdown/knockout RNA-Seq assay for COPS4 is not available on ENCORE database.





77 RBPs can affect the gene expression of COPS4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COPS4ENSG00000138663.4419.26000522.10000-0.316502.242201.68360HepG2ACO1
COPS4ENSG00000138663.4318.00740472.16170-0.570203.732302.45180HepG2CPSF7
COPS4ENSG00000138663.4612.95050463.534800.403002.712001.80900HepG2DDX24
COPS4ENSG00000138663.4241.60730537.06030-1.1524010.167108.79860HepG2DDX55
COPS4ENSG00000138663.4270.66740482.46000-0.833904.261803.06370HepG2DDX59
COPS4ENSG00000138663.4543.46770963.92190-0.826707.851506.86250HepG2DDX6
COPS4ENSG00000138663.4330.56780440.90060-0.415502.406801.74560HepG2DNAJC21
COPS4ENSG00000138663.4272.19650436.92860-0.682706.314305.38670HepG2DNAJC2
COPS4ENSG00000138663.4491.31240926.67610-0.9154010.332509.23240HepG2EIF2S1
COPS4ENSG00000138663.4541.455501024.10270-0.919409.902308.71060HepG2EIF4A3
COPS4ENSG00000138663.4451.59420997.07580-1.1427011.4879010.13280HepG2EIF4B
COPS4ENSG00000138663.4587.17100791.25710-0.430404.609403.57010HepG2EIF4G1
COPS4ENSG00000138663.4387.58480510.12540-0.396302.440901.65680HepG2EWSR1
COPS4ENSG00000138663.4591.54180451.428300.389902.474501.38910HepG2FASTKD2
COPS4ENSG00000138663.4617.478801033.22610-0.742707.687106.57630HepG2FXR1
COPS4ENSG00000138663.4556.13560958.49540-0.785307.738106.65530HepG2G3BP1
COPS4ENSG00000138663.4754.606501017.53090-0.431303.056602.12080HepG2G3BP2
COPS4ENSG00000138663.4418.56620737.12880-0.8165012.4942010.78090HepG2HNRNPA2B1
COPS4ENSG00000138663.4714.61700970.50130-0.441603.327002.56380HepG2HNRNPK
COPS4ENSG00000138663.4556.55620730.71430-0.392804.449603.61020HepG2HNRNPL
COPS4ENSG00000138663.4397.62820491.82030-0.306701.916801.40340HepG2HNRNPU
COPS4ENSG00000138663.4614.55690974.29900-0.664806.103605.13830HepG2IGF2BP2
COPS4ENSG00000138663.4540.993601033.58660-0.9340011.081709.79800HepG2MAGOH
COPS4ENSG00000138663.4713.878801039.37970-0.542003.940403.19970HepG2MATR3
COPS4ENSG00000138663.4663.047701063.86960-0.682106.222405.28860HepG2NCBP2
COPS4ENSG00000138663.4552.11100795.38640-0.526705.841604.73740HepG2NOL12
COPS4ENSG00000138663.4550.34800947.47600-0.783707.986306.77470HepG2PABPC4
COPS4ENSG00000138663.4680.14270980.81710-0.528107.246206.33990HepG2PCBP1
COPS4ENSG00000138663.4410.42330998.03620-1.2820031.8574030.40680HepG2PTBP1
COPS4ENSG00000138663.4570.85150805.92580-0.497507.102906.24240HepG2PUM1
COPS4ENSG00000138663.4669.79070805.35950-0.265901.875301.31720HepG2PUM2
COPS4ENSG00000138663.4312.21620531.78290-0.768309.819308.77950HepG2PUS1
COPS4ENSG00000138663.4768.503701080.85920-0.492105.573704.73360HepG2QKI
COPS4ENSG00000138663.4747.76280536.183600.479801.981201.37490HepG2RAVER1
COPS4ENSG00000138663.4657.350201110.70340-0.7567013.6706012.63820HepG2NELFE
COPS4ENSG00000138663.4700.332401034.49670-0.562808.052507.08290HepG2RECQL
COPS4ENSG00000138663.4266.13620346.29730-0.379801.830801.32070HepG2RPS19
COPS4ENSG00000138663.4667.414401039.05200-0.638609.910708.89270HepG2SF3B4
COPS4ENSG00000138663.4567.33990749.59110-0.401904.152503.41450HepG2SRSF5
COPS4ENSG00000138663.4564.33260882.35760-0.6448010.245609.29980HepG2SRSF9
COPS4ENSG00000138663.4886.86980758.051900.226301.796901.36170HepG2SSB
COPS4ENSG00000138663.4708.34710852.52850-0.267302.560001.95700HepG2SUCLG1
COPS4ENSG00000138663.4628.94900974.88040-0.632308.791507.88330HepG2TAF15
COPS4ENSG00000138663.4624.92840895.74320-0.519405.284104.14110HepG2TIA1
COPS4ENSG00000138663.4332.12600482.16110-0.537803.873903.22930HepG2TRIM56
COPS4ENSG00000138663.4701.39520495.195200.502103.693802.97150HepG2U2AF1
COPS4ENSG00000138663.4550.64590443.994100.310502.238501.62540HepG2ZC3H8
COPS4ENSG00000138663.4664.69780562.364500.241101.819301.35040HepG2ZNF622
COPS4ENSG00000138663.41019.706501337.87170-0.391803.080701.78010K562ABCF1
COPS4ENSG00000138663.41470.134901145.152400.360304.725304.01770K562AGGF1
COPS4ENSG00000138663.41545.812201258.342700.296702.283501.40290K562AKAP8
COPS4ENSG00000138663.41528.284701191.581400.358903.106802.41350K562AKAP8L
COPS4ENSG00000138663.41531.599701250.252600.292702.970402.02560K562ATP5C1
COPS4ENSG00000138663.4741.94020967.14120-0.382403.812302.21440K562BCCIP
COPS4ENSG00000138663.4605.10060801.11980-0.404803.226302.37770K562CPSF6
COPS4ENSG00000138663.4533.30910709.04040-0.410903.343302.16470K562CSTF2
COPS4ENSG00000138663.41551.037501272.106100.285902.170401.58150K562DDX47
COPS4ENSG00000138663.41557.350001282.237200.280302.917402.01590K562DKC1
COPS4ENSG00000138663.4659.37110912.81990-0.469203.636302.23060K562EIF2S1
COPS4ENSG00000138663.4936.908001148.93000-0.294302.673001.96330K562EIF2S2
COPS4ENSG00000138663.4612.64640868.16640-0.502903.600102.66740K562EIF4A3
COPS4ENSG00000138663.41579.298301889.89290-0.259002.577101.66700K562EIF4G2
COPS4ENSG00000138663.4535.32380690.88980-0.368002.096701.30730K562FTO
COPS4ENSG00000138663.41305.258701017.951900.358601.912601.33680K562G3BP2
COPS4ENSG00000138663.4474.40530739.22430-0.639904.241703.51880K562HNRNPC
COPS4ENSG00000138663.41655.075401264.571400.388103.762202.77980K562KIF1C
COPS4ENSG00000138663.4753.072701239.07350-0.7184010.133108.45860K562MAGOH
COPS4ENSG00000138663.4549.64490746.60040-0.441803.486102.49770K562METAP2
COPS4ENSG00000138663.4735.20700915.16400-0.315902.908802.07930K562MTPAP
COPS4ENSG00000138663.41414.84380992.960600.510703.475302.46190K562NAA15
COPS4ENSG00000138663.4797.483801016.77880-0.350502.316901.62810K562NSUN2
COPS4ENSG00000138663.41235.63410697.131500.8256010.605209.12670K562PRPF8
COPS4ENSG00000138663.4752.836101203.80480-0.677208.414707.29700K562PTBP1
COPS4ENSG00000138663.41468.833801151.411600.351203.816903.13680K562RBM15
COPS4ENSG00000138663.4992.82790710.161000.483303.552502.62450K562RPS19
COPS4ENSG00000138663.4771.287501003.37640-0.379503.739502.79920K562SF3A3
COPS4ENSG00000138663.4429.79910573.09810-0.415102.462201.50760K562SRFBP1
COPS4ENSG00000138663.4824.899701027.98750-0.317503.349202.33050K562SRPK2
COPS4ENSG00000138663.4930.36190670.232800.473003.593002.65820K562SYNCRIP
COPS4ENSG00000138663.4882.086201194.42470-0.437303.598002.78770K562TARDBP
COPS4ENSG00000138663.4912.162401152.12970-0.336902.532101.75350K562TIA1
COPS4ENSG00000138663.4919.336001078.11620-0.229801.955601.34410K562UPF1
COPS4ENSG00000138663.4886.143401205.14290-0.443603.356002.02870K562UTP3
COPS4ENSG00000138663.4751.40640922.50340-0.296002.056101.30340K562WDR3
COPS4ENSG00000138663.41369.381401838.40830-0.424904.377603.25080K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COPS4 is not available on ENCORE database.





5 RBPs can affect the splicing of COPS4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOPS4ENSG00000138663.4chr4+8399435883994506839895908398967583996449839969090.096000.000040.01360includedK562FTO
SECOPS4ENSG00000138663.4chr4+8399435883994506839895908398967583996449839969090.069000.005110.09741includedHepG2HNRNPK
SECOPS4ENSG00000138663.4chr4+8399435883994506839895908398967583996449839969090.108000.000060.01633includedHepG2HNRNPA1
SECOPS4ENSG00000138663.4chr4+8399435883994506839895908398967583996449839969090.098000.000140.00930includedHepG2HNRNPU
SECOPS4ENSG00000138663.4chr4+8398621283986308839842288398439983987590839877060.080000.001220.04511includedHepG2HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COPS4 is not avaliable on ENCORE database.