BRE

General Information

Gene Name       : BRE
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: BRE)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BRE is not avaliable on ENCORE database.



Proteins bound to RNA
  • BRE RNA is bound by 22 proteins.  







eCLIP assay for BRE is not avaliable on ENCORE database.





22 proteins are bound to BRE RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr22856129628561386+3'-UTR,CDS,intron-Proximal5.8021523.15150HepG2U2AF2
chr22856129328561398+3'-UTR,CDS,intron-Proximal3.765293.06676K562U2AF2
chr22811367028113757+5'-UTR,intron-Distal,intron-Proximal4.976194.02817HepG2PRPF8
chr22811363928113712+5'-UTR,intron-Distal,intron-Proximal4.346926.42503K562DDX3X
chr22811753528117552+3'-UTR,CDS,intron-Distal,intron-Proximal3.877104.51739HepG2BCLAF1
chr22835213728352180+CDS,intron-Proximal3.728283.14999HepG2GRWD1
chr22826860928268668+CDS,intron-Proximal3.588727.10944HepG2PPIG
chr22821092328210996+3'-UTR,CDS,intron-Proximal5.231073.70131HepG2PRPF8
chr22835213628352199+CDS,intron-Proximal4.144363.53690K562ZNF622
chr22835214328352256+CDS,intron-Proximal3.7759111.46750HepG2BCLAF1
chr22815269628152777+3'-UTR,CDS,intron-Proximal3.2584911.03162HepG2BCLAF1
chr22824821928248264+CDS3.008143.55800HepG2BCLAF1
chr22835218028352254+CDS,intron-Proximal3.153734.02291HepG2GRWD1
chr22815269828152753+3'-UTR,CDS,intron-Proximal3.337604.27261HepG2GRWD1
chr22826861228268667+CDS,intron-Proximal4.1816510.68105HepG2BCLAF1
chr22824816728248217+CDS3.745823.46958K562YBX3
chr22811747828117535+3'-UTR,CDS,intron-Distal3.872827.23562HepG2BCLAF1
chr22811743728117507+3'-UTR,CDS,intron-Distal3.846463.43253K562YBX3
chr22836296928363114+intron-Distal4.369749.78100HepG2PTBP1
chr22849020428490254+intron-Distal3.075443.27276HepG2HNRNPL
chr22835831228358380+intron-Distal3.258803.23296HepG2SUGP2
chr22843105228431125+intron-Distal4.064403.27946HepG2HNRNPM
chr22827107128271150+intron-Distal3.916703.19026HepG2HNRNPL
chr22842517528425258+intron-Distal5.8399411.22511HepG2PCBP2
chr22848459528484637+intron-Distal4.063673.01043HepG2PCBP2
chr22837784728377925+intron-Distal4.966075.07733HepG2PTBP1
chr22848461228484702+intron-Distal3.450764.84707HepG2HNRNPK
chr22853929628539375+intron-Distal4.859903.77360K562GTF2F1
chr22853930128539357+intron-Distal4.133443.85108HepG2GTF2F1
chr22841361628413726+intron-Distal4.092613.05187HepG2QKI
chr22852139528521465+intron-Distal,intron-Proximal5.204979.74743HepG2TIAL1
chr22836296728363101+intron-Distal4.004285.63677K562PTBP1
chr22818869228188782+intron-Distal4.188583.53723HepG2PTBP1
chr22853930128539390+intron-Distal4.963896.35323K562RBFOX2
chr22848463728484708+intron-Distal5.7651510.65318HepG2PCBP2
chr22815537228155530+intron-Distal3.530635.08575HepG2SUGP2
chr22835957928359619+intron-Distal3.914773.54208HepG2SUGP2
chr22852320328523274+intron-Distal3.106967.22866HepG2U2AF2
chr22849025428490320+intron-Distal5.336067.20560HepG2HNRNPL
chr22843145128431572+intron-Distal3.992844.78196HepG2PTBP1
chr22853929528539372+intron-Distal4.232964.35952HepG2PRPF4
chr22833800028338090+intron-Distal3.667953.02891HepG2HNRNPL
chr22840471028404799+intron-Distal4.085033.95960K562SAFB2
chr22842525828425304+intron-Distal5.087327.61882HepG2PCBP2
chr22853929128539368+intron-Distal3.899285.55843HepG2RBFOX2
chr22840660028406683+intron-Distal3.661463.19036K562HNRNPL
chr22855222428552318+intron-Distal3.311303.61076HepG2HLTF
chr22855570128555770+intron-Distal4.282443.53509HepG2HLTF
chr22835225528352338+intron-Proximal3.232043.59771HepG2QKI
chr22852139928521453+intron-Proximal3.811233.43811HepG2TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BRE is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BRE is not available on ENCORE database.

  • 71 RBPs can affect the levels of BRE.  








The Knockdown/knockout RNA-Seq assay for BRE is not available on ENCORE database.





71 RBPs can affect the gene expression of BRE :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BREENSG00000158019.16427.45950726.43900-0.765107.623206.07300HepG2ADAR
BREENSG00000158019.16884.80070669.416500.402302.392501.42080HepG2AKAP8
BREENSG00000158019.16837.59840675.450000.310302.746901.98200HepG2AKAP8L
BREENSG00000158019.161789.36600960.873400.8969026.0975024.37970HepG2AUH
BREENSG00000158019.161194.01350802.462500.573206.078905.23090HepG2BOP1
BREENSG00000158019.161107.29670854.996600.373003.326502.49080HepG2CALR
BREENSG00000158019.16493.48910672.12280-0.445704.733403.90790HepG2CKAP4
BREENSG00000158019.16988.59200421.614601.2294011.346609.83650HepG2CNOT7
BREENSG00000158019.161035.97960736.708500.491704.210703.37790HepG2CPSF6
BREENSG00000158019.161186.00930905.287400.389602.521001.92180HepG2DDX3X
BREENSG00000158019.16717.89740526.320400.447703.251001.84890HepG2DDX47
BREENSG00000158019.161005.77550682.005600.560404.218703.28590HepG2DDX55
BREENSG00000158019.16908.77270731.478700.313002.713802.01510HepG2DNAJC21
BREENSG00000158019.16715.09470506.870900.496403.561902.54350HepG2EIF3D
BREENSG00000158019.16710.374701048.72110-0.562005.218904.11960HepG2EIF4G2
BREENSG00000158019.16740.340901103.17730-0.575408.233407.29110HepG2ETF1
BREENSG00000158019.16643.90380453.031000.507104.496102.97400HepG2FAM120A
BREENSG00000158019.161100.85270628.174100.8093011.727909.66640HepG2FASTKD2
BREENSG00000158019.161258.71260827.397700.605204.787203.79700HepG2FIP1L1
BREENSG00000158019.161212.24830804.662200.591103.900902.58200HepG2FUS
BREENSG00000158019.16601.40080821.24420-0.449502.357001.53910HepG2G3BP2
BREENSG00000158019.16605.93830835.12800-0.462802.911002.25560HepG2GPKOW
BREENSG00000158019.161329.920001019.814800.382905.096303.89300HepG2HNRNPA2B1
BREENSG00000158019.16337.06270783.55980-1.217009.395208.16900HepG2HNRNPK
BREENSG00000158019.16587.81400790.68290-0.427702.242501.35220HepG2KHSRP
BREENSG00000158019.16871.32570530.480900.715804.260902.96820HepG2METAP2
BREENSG00000158019.161079.82900690.740400.644504.568702.73680HepG2NKRF
BREENSG00000158019.16446.65590706.66420-0.661905.529204.49020HepG2NSUN2
BREENSG00000158019.16518.23840727.81100-0.489905.023004.05850HepG2PPIL4
BREENSG00000158019.16382.78110526.19780-0.459102.311101.56950HepG2PRPF8
BREENSG00000158019.161108.66150830.310100.417005.254604.55040HepG2PTBP1
BREENSG00000158019.16234.912501050.35650-2.1607057.4207055.14360HepG2PUF60
BREENSG00000158019.16863.001401115.03180-0.369704.521403.80350HepG2PUM1
BREENSG00000158019.16853.80400684.863100.318003.115002.46950HepG2PUS1
BREENSG00000158019.161426.99290938.966500.603705.190504.06140HepG2RBM15
BREENSG00000158019.161098.73030922.059100.252802.184401.70920HepG2RBM22
BREENSG00000158019.16458.10770816.10890-0.8331010.709909.44240HepG2RBM25
BREENSG00000158019.16671.69840860.64170-0.357603.328702.66080HepG2RECQL
BREENSG00000158019.161378.684601036.801800.411103.342102.60140HepG2RPLP0
BREENSG00000158019.16696.20900495.005500.492003.620902.53960HepG2SERBP1
BREENSG00000158019.16594.14580864.15210-0.540502.987802.28600HepG2SF3A3
BREENSG00000158019.16430.15020788.85650-0.874909.928308.66440HepG2SF3B1
BREENSG00000158019.16569.98130864.43630-0.600807.919007.00010HepG2SF3B4
BREENSG00000158019.16684.979701007.19390-0.556208.719707.58440HepG2SLBP
BREENSG00000158019.161997.949901041.444400.9398032.6752031.44790HepG2SRFBP1
BREENSG00000158019.161148.06430902.294000.347403.799803.26780HepG2SRSF1
BREENSG00000158019.16512.954401037.11240-1.0157022.4160020.87160HepG2SRSF5
BREENSG00000158019.161086.45610904.242200.264702.603502.10070HepG2SSB
BREENSG00000158019.161176.23760735.275700.677705.325303.48270HepG2SUGP2
BREENSG00000158019.16595.43900799.99240-0.426004.635003.94290HepG2TRIM56
BREENSG00000158019.16523.91540766.37020-0.548707.162006.12580HepG2UPF1
BREENSG00000158019.16527.67030379.080900.477002.309201.31600HepG2XPO5
BREENSG00000158019.161410.33170769.357200.8742024.9758023.32240HepG2ZC3H8
BREENSG00000158019.16396.24660555.74170-0.488004.205403.53120K562AGGF1
BREENSG00000158019.16282.15730610.36440-1.1132012.6024011.48180K562AQR
BREENSG00000158019.16851.22390664.165600.357902.752501.58130K562CCDC124
BREENSG00000158019.16402.38350512.17850-0.348102.033601.35310K562CPSF6
BREENSG00000158019.161222.83800725.092900.7539015.2834013.86530K562DDX47
BREENSG00000158019.16213.69290362.56570-0.762705.258203.97830K562EFTUD2
BREENSG00000158019.16649.25000523.773700.309702.188501.53770K562EIF2S2
BREENSG00000158019.16417.68010251.917700.729303.449502.31650K562EIF3A
BREENSG00000158019.16339.58240489.01800-0.526103.499502.61020K562GPKOW
BREENSG00000158019.16204.45610453.05450-1.1479012.1684010.99160K562HNRNPC
BREENSG00000158019.16351.67390506.47660-0.526304.383503.24890K562HNRNPU
BREENSG00000158019.16501.72670378.161200.407802.576101.43820K562IGF2BP3
BREENSG00000158019.16244.94020347.61860-0.505102.733701.75930K562PCBP2
BREENSG00000158019.16357.79430541.52690-0.597903.957002.96220K562PCBP3
BREENSG00000158019.16291.16550415.37000-0.512603.371102.48020K562POLR2G
BREENSG00000158019.16211.03770352.81820-0.741404.445603.49560K562PRPF8
BREENSG00000158019.16415.86920910.34440-1.1303016.3313014.31220K562PUF60
BREENSG00000158019.16426.51530558.77980-0.389702.745202.15410K562RBM15
BREENSG00000158019.16249.86660363.95660-0.542603.310702.38560K562RBM22
BREENSG00000158019.16610.08590359.383500.763405.930704.72920K562RPS19
BREENSG00000158019.16519.63200304.852800.769305.508404.02790K562RPS3
BREENSG00000158019.16230.83440341.60140-0.565502.778101.76030K562SUPV3L1
BREENSG00000158019.16175.26480376.61410-1.1036010.153008.66080K562TARDBP
BREENSG00000158019.16402.14980254.369400.660703.979002.61850K562U2AF1
BREENSG00000158019.16405.73560262.737400.626804.816503.75930K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BRE is not available on ENCORE database.





17 RBPs can affect the splicing of BRE :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEBREENSG00000158019.16chr2+2811524928115315281136582811370928117399281175510.209000.000060.00215includedK562SRSF1
SEBREENSG00000158019.16chr2+2853294828533020285212042852135828561316285617680.164000.000620.01415includedK562SRSF1
SEBREENSG00000158019.16chr2+2845600928456222283521372835224728460068284601680.083000.001830.03400includedHepG2U2AF1
SEBREENSG00000158019.16chr2+285501402855031428521204285213582856131628561768-0.208000.000020.00459excludedHepG2HNRNPM
SEBREENSG00000158019.16chr2+2845600928456222283521372835224728460068284601680.155000.000000.00000includedHepG2HNRNPK
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.130000.002580.05717excludedHepG2HNRNPK
SEBREENSG00000158019.16chr2+2855014028550314285212042852135828561316285617680.201000.000030.00069includedHepG2U2AF2
SEBREENSG00000158019.16chr2+285329482853302028521204285213582856131628561768-0.102000.000080.01262excludedHepG2SRSF7
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.089000.000030.00083excludedK562PUS1
SEBREENSG00000158019.16chr2+2811524928115315281136582811370928117399281175510.180000.000020.00296includedHepG2NCBP2
SEBREENSG00000158019.16chr2+2853294828533020285212042852135828561316285617680.187000.000970.04463includedHepG2SFPQ
SEBREENSG00000158019.16chr2+2845600928456222283521372835224728460068284601680.151000.000300.01836includedHepG2SFPQ
SEBREENSG00000158019.16chr2+2811524928115315281136582811370928117399281175510.180000.000030.00148includedHepG2SRSF1
SEBREENSG00000158019.16chr2+2853294828533020285212042852135828561316285617680.096000.001860.07662includedHepG2PCBP1
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.101000.000060.00387excludedK562UTP18
SEBREENSG00000158019.16chr2+2811524928115315281136582811370928117399281175510.214000.000100.00610includedK562TARDBP
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.102000.000050.00269excludedK562RBM15
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.080000.001090.02969excludedK562AGGF1
SEBREENSG00000158019.16chr2+284676462846772928464189284642602852120428521358-0.059000.002680.08472excludedK562SF3B1
SEBREENSG00000158019.16chr2+285329482853302028521204285213582856131628561768-0.120000.000220.07242excludedHepG2XRN2
SEBREENSG00000158019.16chr2+2853294828533020285212042852135828561316285617680.154000.000000.00037includedHepG2SRSF9
MXEBREENSG00000158019.16chr2+28532948285330202855014028550314285212042852135828561316285617680.447000.006420.079481includedK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for BRE is not avaliable on ENCORE database.