USP16

General Information

Gene Name       : USP16
Gene ID             : ENSG00000156256.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: USP16)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878USP16ENSG00000156256.1441.3535.4538.40ENCSR000AEF
HepG2USP16ENSG00000156256.1414.4227.4020.91ENCSR985KAT
K562USP16ENSG00000156256.1443.8343.7943.81ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
USP16Ribo-STAMP-293TshRNABGRSLV05-37,BGRSLV05-38BGRSLV05-1,BGRSLV05-2NotSatisfiedENCORE2
USP16Ribo-STAMP-293TshRNABGRSLV07-33,BGRSLV07-34BGRSLV07-1,BGRSLV07-2NotSatisfiedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for USP16 is not avaliable on ENCORE database.



Proteins bound to RNA
  • USP16 RNA is bound by 20 proteins.  







eCLIP assay for USP16 is not avaliable on ENCORE database.





20 proteins are bound to USP16 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr213042670030426801+3'-UTR5.083716.23813HepG2SUB1
chr213042673130426794+3'-UTR6.3320110.19274K562PABPC4
chr213039703130397062+5'-UTR3.685938.28018K562YBX3
chr213040007830400215+5'-UTR,CDS,intron-Distal,intron-Proximal3.7486013.73292K562KHSRP
chr213039698930397089+5'-UTR,CDS4.132916.88275HepG2NCBP2
chr213039700330397066+5'-UTR,CDS5.056154.11950K562DDX3X
chr213040021330400279+5'-UTR,CDS,intron-Proximal4.844365.70640HepG2BCLAF1
chr213039702030397031+5'-UTR3.242346.82055K562YBX3
chr213041064630410686+CDS,intron-Distal,intron-Proximal3.238873.65452K562BUD13
chr213041582330415882+CDS3.483403.95301K562ZNF622
chr213041297230413005+CDS,intron-Distal4.469144.70478HepG2BCLAF1
chr213041297830413070+CDS,intron-Distal,intron-Proximal3.591956.70109K562PRPF8
chr213040715630407186+CDS,intron-Distal,intron-Proximal4.234653.53690K562ZNF622
chr213040716230407199+CDS,intron-Distal3.775873.00996K562BUD13
chr213041435430414426+CDS,intron-Distal,intron-Proximal3.797474.39592K562XRCC6
chr213042638630426458+CDS,intron-Proximal3.313404.47973K562YBX3
chr213040966130409692+CDS,intron-Distal3.152333.07653K562ZNF622
chr213041913030419221+CDS3.455876.47196HepG2BCLAF1
chr213042613730426208+CDS4.139076.65960HepG2BCLAF1
chr213040297630403096+CDS,intron-Distal,intron-Proximal3.3975111.91514K562ZNF622
chr213040306430403100+CDS,intron-Distal,intron-Proximal3.831033.86058K562GRWD1
chr213041951030419556+CDS3.791075.06180HepG2BCLAF1
chr213041904130419098+CDS5.057445.68196HepG2BCLAF1
chr213041179030411879+CDS,intron-Distal,intron-Proximal3.186885.48629K562BUD13
chr213040294730403017+CDS,intron-Distal4.385597.09561HepG2BCLAF1
chr213041960330419636+CDS3.967594.80676K562RBM15
chr213041428830414378+CDS,intron-Distal,intron-Proximal5.633846.90654K562SF3B4
chr213041183430411900+CDS,intron-Distal,intron-Proximal4.030345.65086HepG2BCLAF1
chr213041433530414391+CDS,intron-Distal5.283827.49561HepG2BCLAF1
chr213041892130419025+CDS,intron-Proximal4.582237.39649K562U2AF2
chr213041925530419339+CDS3.197465.75243K562ZNF622
chr213041945330419501+CDS3.428104.22563K562UCHL5
chr213041897730419011+CDS,intron-Proximal4.169403.81597K562RBM15
chr213041957430419627+CDS3.548264.49347K562UCHL5
chr213041959030419603+CDS4.811365.17013K562RBM15
chr213041522330415267+intron-Distal3.284944.10408K562KHSRP
chr213042034730420469+intron-Distal3.978784.00200K562EIF4G2
chr213039999830400077+intron-Distal3.6783511.26860K562KHSRP
chr213039906130399144+intron-Distal,intron-Proximal4.5592012.23779K562KHSRP
chr213039811230398240+intron-Distal,intron-Proximal3.974755.75173HepG2QKI
chr213041549830415598+intron-Distal4.2654519.44312K562KHSRP
chr213042122130421337+intron-Distal,intron-Proximal3.172214.14287K562KHSRP
chr213041550830415573+intron-Distal4.962758.29628K562TIA1
chr213041553030415604+intron-Distal4.251014.00239HepG2KHSRP
chr213041543730415497+intron-Distal3.889806.41553K562KHSRP
chr213041450530414588+intron-Distal,intron-Proximal3.625618.47371K562KHSRP
chr213041964530419666+intron-Proximal4.492113.62536K562AQR
chr213041489930414938+intron-Proximal3.680393.07287K562TIA1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for USP16 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for USP16 is not available on ENCORE database.

  • 73 RBPs can affect the levels of USP16.  








The Knockdown/knockout RNA-Seq assay for USP16 is not available on ENCORE database.





73 RBPs can affect the gene expression of USP16 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
USP16ENSG00000156256.10606.09520863.26580-0.510303.329002.19360HepG2AKAP8
USP16ENSG00000156256.10930.082801188.99750-0.354302.297301.57900HepG2ASCC1
USP16ENSG00000156256.101192.401101462.27200-0.294303.508802.75240HepG2AUH
USP16ENSG00000156256.10571.89290828.09410-0.534003.056002.06810HepG2BCCIP
USP16ENSG00000156256.10842.165401365.00320-0.696703.247702.18710HepG2CCAR1
USP16ENSG00000156256.10894.065001129.62500-0.337402.126601.44330HepG2CIRBP
USP16ENSG00000156256.101137.66420918.143900.309203.706502.95750HepG2CKAP4
USP16ENSG00000156256.10652.053201146.33670-0.8140015.7427014.45640HepG2CELF1
USP16ENSG00000156256.101020.549701232.57310-0.272303.059002.28600HepG2DAZAP1
USP16ENSG00000156256.101017.41060761.858800.417202.698601.42600HepG2DDX27
USP16ENSG00000156256.10716.091201376.55190-0.9428012.4543011.21630HepG2DDX3X
USP16ENSG00000156256.10698.097801182.41590-0.760207.179206.22350HepG2DDX6
USP16ENSG00000156256.10453.81680656.06720-0.531706.672905.72160HepG2DNAJC2
USP16ENSG00000156256.10766.820401136.75520-0.568004.909804.13160HepG2EIF2S1
USP16ENSG00000156256.10815.979901223.10210-0.583903.849803.04300HepG2EIF4B
USP16ENSG00000156256.101840.315901216.026500.597708.600007.27590HepG2EIF4G1
USP16ENSG00000156256.10871.000901164.87240-0.419403.108502.24670HepG2EIF4G2
USP16ENSG00000156256.10732.02450993.29730-0.440302.752701.98540HepG2FIP1L1
USP16ENSG00000156256.10847.745301267.43330-0.580205.376104.43230HepG2FXR1
USP16ENSG00000156256.10899.033501175.78420-0.387202.466301.83630HepG2G3BP1
USP16ENSG00000156256.10495.02990813.81600-0.717204.848103.38390HepG2GRSF1
USP16ENSG00000156256.10502.94810668.31990-0.410102.043401.47800HepG2HNRNPA1
USP16ENSG00000156256.10525.27450743.36040-0.501003.871003.06190HepG2HNRNPC
USP16ENSG00000156256.10936.292601122.77360-0.262002.859302.17640HepG2HNRNPL
USP16ENSG00000156256.10583.19920754.30330-0.371204.190303.30650HepG2ILF2
USP16ENSG00000156256.10712.143601274.98820-0.840208.956007.87440HepG2MATR3
USP16ENSG00000156256.10632.75120804.00500-0.345602.186601.46240HepG2MSI2
USP16ENSG00000156256.10979.973301305.03490-0.413302.869102.22490HepG2NCBP2
USP16ENSG00000156256.10914.900501222.21810-0.417804.599003.61560HepG2NOL12
USP16ENSG00000156256.10907.519701162.28100-0.357002.253901.59700HepG2PABPC4
USP16ENSG00000156256.10960.950601212.35420-0.335303.627003.01900HepG2PTBP1
USP16ENSG00000156256.10906.876401166.71970-0.363502.962402.34900HepG2PUF60
USP16ENSG00000156256.101001.244501238.53100-0.306804.008703.32300HepG2PUM1
USP16ENSG00000156256.10736.80910935.31390-0.344203.783003.08600HepG2PUS1
USP16ENSG00000156256.10961.581601313.02320-0.449405.330404.50430HepG2QKI
USP16ENSG00000156256.101607.61410886.775100.858205.998204.98650HepG2RAVER1
USP16ENSG00000156256.101537.430801191.647800.367503.452702.70560HepG2RBM25
USP16ENSG00000156256.10492.86570761.10590-0.626903.634802.41810HepG2RCC2
USP16ENSG00000156256.101069.377901349.23920-0.335403.848503.23030HepG2NELFE
USP16ENSG00000156256.101068.856001256.62330-0.233502.121101.57230HepG2RECQL
USP16ENSG00000156256.101276.989201061.587500.266401.935501.35180HepG2RPLP0
USP16ENSG00000156256.10927.16420621.456800.577104.616503.63110HepG2RRP9
USP16ENSG00000156256.10717.616701082.12060-0.592604.266403.41870HepG2SF3A3
USP16ENSG00000156256.101262.29100928.107200.443603.781202.96790HepG2SF3B1
USP16ENSG00000156256.10562.00470766.93290-0.448505.503304.64780HepG2SMN1
USP16ENSG00000156256.10779.93860968.30840-0.312102.656901.97490HepG2SRSF7
USP16ENSG00000156256.101126.253001310.10460-0.218202.151601.59030HepG2SUCLG1
USP16ENSG00000156256.10909.576601184.19730-0.380604.328803.65130HepG2TAF15
USP16ENSG00000156256.10532.55850717.62170-0.430302.491302.01250HepG2TIAL1
USP16ENSG00000156256.10456.56080723.94860-0.665109.403308.45740HepG2TRIM56
USP16ENSG00000156256.101087.81630753.421300.529808.728107.64660HepG2ZC3H8
USP16ENSG00000156256.10821.745101055.45920-0.361104.780304.11120HepG2ZNF622
USP16ENSG00000156256.101575.236502530.12130-0.6836018.4265017.08300K562AGGF1
USP16ENSG00000156256.101617.454001936.41360-0.259702.768201.45700K562BCCIP
USP16ENSG00000156256.10459.53480659.17900-0.520504.041602.71990K562CCAR1
USP16ENSG00000156256.101193.598701419.66880-0.250202.395501.42210K562CSTF2
USP16ENSG00000156256.101948.240501640.738300.247702.742801.42920K562DDX27
USP16ENSG00000156256.101332.094801649.29800-0.308202.804801.75570K562DDX3X
USP16ENSG00000156256.103741.538702971.502700.332305.944805.04140K562DDX47
USP16ENSG00000156256.102119.687201809.443600.228202.102401.40140K562EIF3G
USP16ENSG00000156256.102101.923001791.909100.230102.322701.76020K562FXR1
USP16ENSG00000156256.102778.882801844.692200.591004.941803.93330K562G3BP2
USP16ENSG00000156256.102344.627701960.634200.257902.734901.60170K562GLRX3
USP16ENSG00000156256.102193.622703359.04440-0.614709.056607.66800K562GRSF1
USP16ENSG00000156256.102216.474001343.015700.7227012.7588011.55330K562HNRNPC
USP16ENSG00000156256.102741.612102064.156600.409403.634702.19440K562HNRNPK
USP16ENSG00000156256.10999.15810688.662600.536804.400602.51020K562ILF3
USP16ENSG00000156256.102003.832601437.681300.478903.348602.31130K562KRR1
USP16ENSG00000156256.105532.482104436.212800.318503.353201.68890K562NOL12
USP16ENSG00000156256.102398.008801932.519700.311302.770701.79010K562PCBP2
USP16ENSG00000156256.101211.341902031.45650-0.745909.295207.77700K562PCBP3
USP16ENSG00000156256.10977.832301558.22670-0.6722010.518609.00040K562POLR2G
USP16ENSG00000156256.102326.221201519.527800.614307.905106.63040K562PRPF8
USP16ENSG00000156256.10939.826801204.13530-0.357502.409801.57140K562PSIP1
USP16ENSG00000156256.105285.423104425.431000.256102.021101.32290K562PUF60
USP16ENSG00000156256.102591.996401760.199900.558203.318901.73520K562RAVER1
USP16ENSG00000156256.10758.317701098.52610-0.534706.129404.65130K562RCC2
USP16ENSG00000156256.101178.272102259.96560-0.9396027.9216025.63530K562SF3A3
USP16ENSG00000156256.10740.449301041.38280-0.492004.334702.96560K562SRFBP1
USP16ENSG00000156256.101188.380401569.44660-0.401303.974602.67900K562SRSF4
USP16ENSG00000156256.102110.757401562.900100.433405.744404.55380K562SYNCRIP
USP16ENSG00000156256.10974.360701230.32290-0.336502.465101.58120K562TRIM56
USP16ENSG00000156256.102304.596901788.825900.365402.603201.54570K562U2AF1
USP16ENSG00000156256.102281.091501847.232400.304303.228602.36270K562U2AF2
USP16ENSG00000156256.102727.818502160.869600.336006.413705.17630K562WDR43
USP16ENSG00000156256.102347.183901431.835500.713004.018002.02590K562XRCC6
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for USP16 is not available on ENCORE database.





18 RBPs can affect the splicing of USP16 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEUSP16ENSG00000156256.10chr21+3039888730398982303969763039709830400193304002950.072000.000000.00001includedK562AQR
SEUSP16ENSG00000156256.10chr21+304001933040029530396971303970983040291530403094-0.073000.000000.00000excludedK562AQR
SEUSP16ENSG00000156256.10chr21+304189873041910130415701304159203041929530419452-0.096000.000060.00105excludedK562AQR
SEUSP16ENSG00000156256.10chr21+304129293041300830411801304118893041433330414425-0.184000.000000.00012excludedK562PUS1
SEUSP16ENSG00000156256.10chr21+304001713040029530396949303970983040291530403094-0.068000.005290.06503excludedK562PUS1
SEUSP16ENSG00000156256.10chr21+3039802930398092303969713039709830400193304002950.131000.000000.00000includedHepG2PTBP1
SEUSP16ENSG00000156256.10chr21+304129293041300830411801304118893041433330414425-0.111000.005540.08770excludedK562U2AF1
SEUSP16ENSG00000156256.10chr21+304001713040029530396949303970983040291530403094-0.093000.000420.01769excludedK562UTP18
SEUSP16ENSG00000156256.10chr21+304129293041300830411801304118893041433330414425-0.112000.000970.02685excludedK562RBM15
SEUSP16ENSG00000156256.10chr21+304129293041300830411801304118893041433330414425-0.089000.005040.09369excludedK562AGGF1
SEUSP16ENSG00000156256.10chr21+303988873039898230396976303970983040019330400295-0.056000.000000.00008excludedK562HNRNPK
SEUSP16ENSG00000156256.10chr21+3039802930398092303969713039709830400193304002950.404000.000000.00000includedK562PTBP1
SEUSP16ENSG00000156256.10chr21+303988873039898230396976303970983040019330400295-0.068000.000000.00004excludedK562PTBP1
SEUSP16ENSG00000156256.10chr21+3039888730398982303969763039709830400193304002950.226000.000000.00000includedK562HNRNPC
SEUSP16ENSG00000156256.10chr21+3041898730419101304147923041592030419548304196420.116000.001850.03179includedK562HNRNPC
A3SSUSP16ENSG00000156256.10chr21+3042238430422499304224123042249930421081304211760.059000.000000.00000longerK562AQR
A5SSUSP16ENSG00000156256.10chr21+304112433041147730411243304114663041180130411897-0.085000.000030.00095shorterK562AQR
A5SSUSP16ENSG00000156256.10chr21+304113463041147730411346304114663041180130411889-0.130000.000320.02926shorterK562HNRNPC
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.144000.000000.00000includedK562PUS1
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.102000.011340.09496includedHepG2SF3A3
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.081000.009980.06068includedHepG2U2AF2
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.114000.000760.04309includedHepG2HNRNPUL1
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.124000.000020.00035includedK562AGGF1
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.090000.001150.02609includedHepG2IGF2BP3
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.064000.005630.04870includedK562AKAP8L
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.211000.000000.00000includedHepG2U2AF1
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.111000.000010.00023includedK562RBM15
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.081000.000140.04862includedK562DDX21
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.148000.001210.02362includedHepG2FUBP3
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.090000.000970.01312includedHepG2HNRNPK
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.109000.000020.00043includedK562UTP18
RIUSP16ENSG00000156256.10chr21+304147923041592030414792304148493041574330415920-0.054000.000950.05793excludedK562SAFB
RIUSP16ENSG00000156256.10chr21+3041479230415920304147923041484930415743304159200.054000.000190.00147includedK562AQR
MXEUSP16ENSG00000156256.10chr21+30422379304224993042612230426279304210813042117630426386304265610.058000.000000.000011includedK562AQR
MXEUSP16ENSG00000156256.10chr21+30402915304030943040715730407261303969493039709830408591304086950.101000.000000.000001includedK562AQR
MXEUSP16ENSG00000156256.10chr21+30422384304224993042612230426279304210813042117630426386304268090.079000.000000.000001includedK562AQR
MXEUSP16ENSG00000156256.10chr21+3041898730419101304192953041945230415743304159203041954830419642-0.054000.000030.000402includedK562AQR
MXEUSP16ENSG00000156256.10chr21+30422412304224993042612230426279304210813042117630426386304268090.141000.002010.068861includedK562SAFB
MXEUSP16ENSG00000156256.10chr21+30411346304114663041180130411889304106553041075130412929304130080.150000.000400.038501includedK562RBM22

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for USP16 is not avaliable on ENCORE database.