TTC7A

General Information

Gene Name       : TTC7A
Gene ID             : ENSG00000068724.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TTC7A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TTC7AENSG00000068724.157.8317.2712.55ENCSR000AEF
HepG2TTC7AENSG00000068724.1526.6414.9620.80ENCSR985KAT
K562TTC7AENSG00000068724.156.345.155.75ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TTC7A is not avaliable on ENCORE database.



Proteins bound to RNA
  • TTC7A RNA is bound by 19 proteins.  







eCLIP assay for TTC7A is not avaliable on ENCORE database.





19 proteins are bound to TTC7A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr24723849447238581+3'-UTR,5'-UTR,CDS,intron-Proximal3.265484.85880HepG2PPIG
chr24727900747279066+3'-UTR,CDS,intron-Proximal5.054257.92973HepG2PRPF8
chr24730237347302428+3'-UTR5.851516.06289K562PUM2
chr24725649647256565+3'-UTR,CDS,intron-Proximal3.8187111.40182HepG2PRPF8
chr24727348747273564+3'-UTR,CDS,intron-Distal4.174485.24452HepG2PPIG
chr24727709847277182+3'-UTR,CDS3.647446.81103HepG2PPIG
chr24730218747302326+3'-UTR3.694865.40760HepG2UPF1
chr24718567147185812+5'-UTR,intron-Distal,intron-Proximal4.6046514.78532HepG2RBFOX2
chr24722059247220654+5'-UTR,CDS3.6736810.93644HepG2PPIG
chr24723381847233864+5'-UTR,CDS,intron-Proximal3.303916.93667HepG2PPIG
chr24720203847202155+5'-UTR,CDS,intron-Proximal3.574534.01088HepG2RBFOX2
chr24717764647177710+5'-UTR,CDS,intron-Proximal3.900196.18341HepG2PRPF8
chr24720595747206042+5'-UTR,CDS3.3325410.14543HepG2PPIG
chr24722148747221551+5'-UTR,CDS,intron-Distal,intron-Proximal3.4765811.11819HepG2PPIG
chr24718413647184152+5'-UTR,CDS,intron-Proximal4.7814415.51998HepG2PRPF8
chr24720595647206044+5'-UTR,CDS3.517575.15776HepG2BCLAF1
chr24723313347233204+5'-UTR,CDS,intron-Proximal4.258464.69071HepG2GRWD1
chr24722065447220669+5'-UTR,CDS,intron-Proximal4.419609.28243HepG2PPIG
chr24722224747222330+5'-UTR,CDS,intron-Proximal3.456243.67894HepG2AQR
chr24716847347168546+5'-UTR,intron-Distal3.727827.94128HepG2DDX3X
chr24718407447184183+5'-UTR,CDS,intron-Proximal3.201565.57447HepG2GRWD1
chr24725288047252992+intron-Distal4.942897.06641HepG2PCBP2
chr24723611147236182+intron-Distal4.112417.32957HepG2RBFOX2
chr24722638047226499+intron-Distal3.199813.59783HepG2HNRNPK
chr24723864547238740+intron-Distal,intron-Proximal4.802966.34754HepG2RBFOX2
chr24723431947234371+intron-Distal6.7248356.02109HepG2RBFOX2
chr24722615847226269+intron-Distal3.941759.46623HepG2HNRNPL
chr24723430447234414+intron-Distal4.662596.01965K562RBFOX2
chr24726284247262979+intron-Distal3.072964.53269HepG2HNRNPM
chr24718587247185993+intron-Distal5.1798324.56620HepG2RBFOX2
chr24723434847234438+intron-Distal4.272934.59677K562DROSHA
chr24718967747189747+intron-Distal3.839983.29248HepG2SUGP2
chr24725290847253002+intron-Distal3.199813.59783HepG2HNRNPK
chr24723518947235263+intron-Distal5.2439319.97307HepG2RBFOX2
chr24723641847236508+intron-Distal3.849064.59145HepG2XPO5
chr24723434547234454+intron-Distal3.079693.11108HepG2DROSHA
chr24723397747234034+intron-Distal4.6383011.95397HepG2RBFOX2
chr24723437147234430+intron-Distal6.2251178.08812HepG2RBFOX2
chr24723435047234429+intron-Distal5.232576.54999HepG2DDX6
chr24722644047226548+intron-Distal3.703688.06500HepG2HNRNPL
chr24718581247185872+intron-Distal5.6787613.43272HepG2RBFOX2
chr24723669647236744+intron-Distal4.049863.14375HepG2RBFOX2
chr24723513847235189+intron-Distal5.7036814.15858HepG2RBFOX2
chr24722648447226562+intron-Distal5.6236610.16517K562AGGF1
chr24723481447234873+intron-Distal5.582579.16480HepG2RBFOX2
chr24723703947237121+intron-Distal4.709574.43116HepG2RBFOX2
chr24722626347226358+intron-Distal4.188908.84940K562AGGF1
chr24723625347236302+intron-Distal4.154764.17531HepG2RBFOX2
chr24719046747190519+intron-Distal3.922023.63454HepG2SUGP2
chr24719483647194942+intron-Distal4.851625.89032HepG2QKI
chr24722655447226621+intron-Distal3.771189.70093HepG2HNRNPL
chr24722234247222433+intron-Proximal5.370319.94888HepG2PRPF8
chr24718415247184168+intron-Proximal4.5744314.95101HepG2PRPF8
chr24718416847184189+intron-Proximal4.2686714.10710HepG2PRPF8
chr24723320147233242+intron-Proximal3.446324.54206HepG2PRPF8
chr24718414647184191+intron-Proximal3.867475.90528HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TTC7A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TTC7A is not available on ENCORE database.

  • 75 RBPs can affect the levels of TTC7A.  








The Knockdown/knockout RNA-Seq assay for TTC7A is not available on ENCORE database.





75 RBPs can affect the gene expression of TTC7A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TTC7AENSG00000068724.111065.817801287.02720-0.272103.050602.41660HepG2ACO1
TTC7AENSG00000068724.11593.09530793.07500-0.419202.868001.85320HepG2ADAR
TTC7AENSG00000068724.11956.560202024.01650-1.0813015.3593014.21000HepG2AKAP1
TTC7AENSG00000068724.11974.966001292.92200-0.407205.537804.48680HepG2AKAP8L
TTC7AENSG00000068724.11789.682701674.60800-1.0845017.3641015.58840HepG2ASCC1
TTC7AENSG00000068724.111923.660801598.968000.266603.305302.56600HepG2AUH
TTC7AENSG00000068724.11430.37200728.85000-0.760007.843306.89950HepG2BOP1
TTC7AENSG00000068724.111256.311901591.02380-0.340802.040401.37000HepG2CIRBP
TTC7AENSG00000068724.11762.223701286.56470-0.7552014.4902013.21670HepG2CKAP4
TTC7AENSG00000068724.11720.028701099.03250-0.610103.539602.66820HepG2CNOT7
TTC7AENSG00000068724.111746.939901229.785100.506307.993407.00810HepG2CELF1
TTC7AENSG00000068724.111301.11590869.035800.582206.642305.64100HepG2DDX21
TTC7AENSG00000068724.11626.37450850.80180-0.441803.776802.69880HepG2DDX24
TTC7AENSG00000068724.112485.571301938.649100.358402.654302.04040HepG2DDX3X
TTC7AENSG00000068724.111124.51090798.569700.493706.530805.48440HepG2DNAJC21
TTC7AENSG00000068724.11670.392801015.49910-0.599106.928505.17090HepG2EIF2S2
TTC7AENSG00000068724.11549.71260769.70110-0.485603.273302.29600HepG2EIF3D
TTC7AENSG00000068724.111206.982301768.96830-0.551504.793203.95500HepG2EIF4A3
TTC7AENSG00000068724.11774.768301722.78260-1.1529013.7241012.25750HepG2EIF4B
TTC7AENSG00000068724.111724.689201249.634100.464704.733203.68570HepG2EIF4G2
TTC7AENSG00000068724.11793.857401159.66620-0.546805.489803.99720HepG2ESF1
TTC7AENSG00000068724.111146.286301835.83960-0.6795015.8002014.55680HepG2ETF1
TTC7AENSG00000068724.111001.863501257.49330-0.327902.703201.87760HepG2EWSR1
TTC7AENSG00000068724.11495.66830688.06410-0.473204.242502.76630HepG2FAM120A
TTC7AENSG00000068724.11837.242601351.86790-0.691206.286205.17240HepG2FIP1L1
TTC7AENSG00000068724.11747.279301154.61610-0.627707.758306.47860HepG2FUBP3
TTC7AENSG00000068724.111104.007801655.96000-0.584905.507504.58200HepG2G3BP1
TTC7AENSG00000068724.11981.196601758.49720-0.8417011.758009.93990HepG2G3BP2
TTC7AENSG00000068724.11550.963901017.53390-0.885006.176004.50640HepG2GRSF1
TTC7AENSG00000068724.111263.797601040.733100.280102.982802.24020HepG2HNRNPF
TTC7AENSG00000068724.111020.495801677.67330-0.717208.783207.59040HepG2HNRNPK
TTC7AENSG00000068724.11968.558201204.34710-0.314303.647702.88080HepG2HNRNPL
TTC7AENSG00000068724.111050.816001529.56560-0.541604.175702.65790HepG2HSPD1
TTC7AENSG00000068724.111445.303301024.827800.495906.322705.27200HepG2IGF2BP1
TTC7AENSG00000068724.111121.033001796.02720-0.680006.864505.90240HepG2MATR3
TTC7AENSG00000068724.111879.478401004.766900.903406.832505.39600HepG2PABPC1
TTC7AENSG00000068724.11569.96770881.77680-0.629509.184407.78550HepG2PARN
TTC7AENSG00000068724.111061.516601693.47370-0.6739015.6446014.39160HepG2PCBP1
TTC7AENSG00000068724.11548.87990953.69370-0.7970014.5488012.99630HepG2PRPF4
TTC7AENSG00000068724.11834.460801723.14090-1.0461032.0834030.63030HepG2PTBP1
TTC7AENSG00000068724.111053.958401328.64710-0.334104.538403.81890HepG2PUM1
TTC7AENSG00000068724.111087.995601310.89390-0.268903.001602.36680HepG2PUS1
TTC7AENSG00000068724.111017.605301866.27210-0.8750020.2394018.77190HepG2QKI
TTC7AENSG00000068724.11869.056201534.42000-0.8202017.2929016.22430HepG2RBM22
TTC7AENSG00000068724.11866.690201693.73620-0.9666019.7746018.07930HepG2RBM25
TTC7AENSG00000068724.11895.217701127.91470-0.333302.245001.36050HepG2RBM27
TTC7AENSG00000068724.111332.951201917.71690-0.5248010.173009.25680HepG2NELFE
TTC7AENSG00000068724.111163.831901786.04450-0.6179013.4336012.23050HepG2RECQL
TTC7AENSG00000068724.111397.465201121.082400.317802.567401.90560HepG2RPLP0
TTC7AENSG00000068724.11547.98470749.02640-0.450903.665802.96800HepG2RPS19
TTC7AENSG00000068724.11417.49680686.83270-0.718206.057404.94160HepG2RRP9
TTC7AENSG00000068724.111148.47720793.337900.533606.955006.00110HepG2SAFB2
TTC7AENSG00000068724.111119.357401794.06930-0.6806015.6464014.41660HepG2SF3B4
TTC7AENSG00000068724.111439.524501200.163100.262303.477102.70550HepG2SLBP
TTC7AENSG00000068724.111029.298401872.59660-0.8634025.4597024.34170HepG2SRSF1
TTC7AENSG00000068724.11486.35160770.91920-0.664604.448103.14970HepG2SRSF3
TTC7AENSG00000068724.11870.574401524.43130-0.808208.345906.29410HepG2SSRP1
TTC7AENSG00000068724.11626.17200960.93960-0.617903.203302.01220HepG2STIP1
TTC7AENSG00000068724.111011.381701405.39770-0.474708.096307.12670HepG2SUCLG1
TTC7AENSG00000068724.111032.212501683.09800-0.7054014.1405013.01860HepG2TAF15
TTC7AENSG00000068724.111279.91210865.580000.564207.789307.02820HepG2TIAL1
TTC7AENSG00000068724.111982.500101294.381200.615006.391205.08570HepG2UBE2L3
TTC7AENSG00000068724.11808.670801014.00230-0.326402.426301.43390HepG2UTP18
TTC7AENSG00000068724.111992.550601084.997400.8768034.0651032.69640HepG2ZNF622
TTC7AENSG00000068724.11459.61750613.83370-0.417402.452401.89350K562AQR
TTC7AENSG00000068724.11393.69970551.26840-0.485704.404503.60800K562DDX47
TTC7AENSG00000068724.11229.47660334.94320-0.545602.752501.62980K562FKBP4
TTC7AENSG00000068724.11346.58010498.17640-0.523504.290503.56060K562FXR1
TTC7AENSG00000068724.1199.97630246.74000-1.303308.419307.04500K562G3BP2
TTC7AENSG00000068724.11410.07820554.24920-0.434602.738701.98590K562GRSF1
TTC7AENSG00000068724.11389.99580556.88370-0.513904.025602.73010K562HNRNPA1
TTC7AENSG00000068724.11628.71510390.537400.686802.215201.32630K562IGF2BP2
TTC7AENSG00000068724.11547.00980761.30630-0.476903.980502.17020K562NOL12
TTC7AENSG00000068724.11205.19240300.15090-0.548702.680801.94280K562PRPF8
TTC7AENSG00000068724.11188.71410256.38540-0.442102.158401.40370K562SF3B4
TTC7AENSG00000068724.11471.39140353.330300.415802.370701.50650K562TRIM56
TTC7AENSG00000068724.11139.23910246.86840-0.826205.394804.27730K562U2AF2
TTC7AENSG00000068724.11798.33510558.530900.515306.171005.14850K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TTC7A is not available on ENCORE database.





9 RBPs can affect the splicing of TTC7A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.162000.000000.00022includedHepG2G3BP1
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.167000.000000.00006includedHepG2RBM22
SETTC7AENSG00000068724.11chr2+4718551047185691471839774718414647202111472022420.137000.000330.03609includedHepG2PRPF8
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.100000.000180.01634includedHepG2AKAP1
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.310000.000000.00000includedHepG2PTBP1
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.180000.000010.00262includedHepG2SUPV3L1
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.096000.000320.07775includedHepG2NOL12
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.129000.000640.09807includedHepG2DDX55
SETTC7AENSG00000068724.11chr2+472734534727357047256362472565234727708747277185-0.237000.001580.05541excludedHepG2HNRNPC
SETTC7AENSG00000068724.11chr2+4718563347185691471839774718414647202111472022420.227000.001300.04907includedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TTC7A is not avaliable on ENCORE database.