TMEM177

General Information

Gene Name       : TMEM177
Gene ID             : ENSG00000144120.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TMEM177)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TMEM177ENSG00000144120.125.0510.597.82ENCSR000AEF
HepG2TMEM177ENSG00000144120.1236.0233.9534.98ENCSR985KAT
K562TMEM177ENSG00000144120.1222.9620.3021.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TMEM177 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TMEM177 RNA is bound by 6 proteins.  







eCLIP assay for TMEM177 is not avaliable on ENCORE database.





6 proteins are bound to TMEM177 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2120438380120438461+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.735736.94346HepG2BUD13
chr2120438423120438515+3'-UTR,5'-UTR,CDS,intron-Distal4.722444.11950K562DDX3X
chr2120436786120436811+5'-UTR,intron-Proximal3.164377.74688HepG2PRPF8
chr2120436749120436883+5'-UTR,intron-Proximal4.326048.63366HepG2NCBP2
chr2120436811120436845+5'-UTR,intron-Proximal4.1844711.70689HepG2PRPF8
chr2120436775120436879+5'-UTR,intron-Proximal4.896405.39850K562DDX3X
chr2120441499120441572+intron-Distal4.792585.30668HepG2RBFOX2
chr2120441502120441648+intron-Distal4.663606.58841HepG2HNRNPK
chr2120441700120441787+intron-Distal3.036323.14359HepG2HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TMEM177 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TMEM177 is not available on ENCORE database.

  • 62 RBPs can affect the levels of TMEM177.  








The Knockdown/knockout RNA-Seq assay for TMEM177 is not available on ENCORE database.





62 RBPs can affect the gene expression of TMEM177 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TMEM177ENSG00000144120.8280.10540409.72240-0.548703.357802.18290HepG2AATF
TMEM177ENSG00000144120.8376.67700513.90170-0.448203.905503.20690HepG2ACO1
TMEM177ENSG00000144120.8574.69860949.73330-0.724705.994005.24570HepG2AKAP1
TMEM177ENSG00000144120.8660.85920516.291100.356102.976102.18340HepG2AKAP8L
TMEM177ENSG00000144120.8592.45810808.52090-0.448604.939504.06570HepG2AUH
TMEM177ENSG00000144120.8650.13920513.759800.339603.006302.31930HepG2CKAP4
TMEM177ENSG00000144120.8607.88490475.271600.354903.273902.37370HepG2DDX19B
TMEM177ENSG00000144120.8350.48040452.11640-0.367401.955701.37280HepG2DDX21
TMEM177ENSG00000144120.8469.34730781.55860-0.735705.935605.05950HepG2DDX6
TMEM177ENSG00000144120.8559.56130435.540500.361402.575201.89250HepG2DNAJC21
TMEM177ENSG00000144120.8577.93300431.650000.420904.108803.34520HepG2DNAJC2
TMEM177ENSG00000144120.8549.93650751.26080-0.450002.850302.24900HepG2EIF2S1
TMEM177ENSG00000144120.81127.95830830.197300.442102.851102.20310HepG2EIF4A3
TMEM177ENSG00000144120.8465.90370808.37870-0.795005.744704.77760HepG2EIF4B
TMEM177ENSG00000144120.8782.12520928.31490-0.247202.133001.59150HepG2ETF1
TMEM177ENSG00000144120.8693.76240502.147000.466203.737702.76800HepG2EWSR1
TMEM177ENSG00000144120.8423.95660662.15260-0.643204.556003.58540HepG2FIP1L1
TMEM177ENSG00000144120.8584.94610777.07010-0.409702.427001.80190HepG2G3BP1
TMEM177ENSG00000144120.8624.17920439.712600.505303.659202.93060HepG2HNRNPA1
TMEM177ENSG00000144120.8735.11190615.872300.255202.031001.40960HepG2HNRNPF
TMEM177ENSG00000144120.8614.12250862.54080-0.490103.394402.69590HepG2NCBP2
TMEM177ENSG00000144120.8571.17710768.08610-0.427302.667401.95780HepG2PABPC4
TMEM177ENSG00000144120.8360.76700480.92850-0.414803.065102.17790HepG2PARN
TMEM177ENSG00000144120.8247.18600476.41530-0.946609.822308.49710HepG2PRPF4
TMEM177ENSG00000144120.8570.90960771.14490-0.433704.275903.62760HepG2PTBP1
TMEM177ENSG00000144120.8615.03020835.24150-0.441504.214103.46680HepG2QKI
TMEM177ENSG00000144120.8240.55480440.06000-0.871302.643801.95440HepG2RAVER1
TMEM177ENSG00000144120.8583.45690775.89430-0.411203.475402.91310HepG2RBM22
TMEM177ENSG00000144120.8521.66140758.00800-0.539105.065204.17890HepG2RBM25
TMEM177ENSG00000144120.8607.90640799.28120-0.394903.911903.19590HepG2RECQL
TMEM177ENSG00000144120.8456.31390257.499600.825405.316004.20230HepG2RPS3A
TMEM177ENSG00000144120.8555.45620432.681200.360302.843902.19310HepG2SAFB2
TMEM177ENSG00000144120.8599.90830802.92240-0.420504.268403.55850HepG2SF3B4
TMEM177ENSG00000144120.8509.09940876.33500-0.7835013.3469012.46600HepG2SRFBP1
TMEM177ENSG00000144120.8187.35730417.36630-1.155508.699506.84150HepG2SRSF3
TMEM177ENSG00000144120.8377.29630681.77870-0.8536013.9319012.86300HepG2SRSF9
TMEM177ENSG00000144120.81057.79550760.850400.475306.621405.89270HepG2SSB
TMEM177ENSG00000144120.8497.55450753.20490-0.598207.008906.18600HepG2TAF15
TMEM177ENSG00000144120.8677.76790424.879800.673602.598901.56120HepG2TBRG4
TMEM177ENSG00000144120.8687.89480575.143300.258201.939501.33720HepG2UPF1
TMEM177ENSG00000144120.8339.21000470.12910-0.470902.490001.84730HepG2ZC3H8
TMEM177ENSG00000144120.8760.64380632.548000.265902.325501.81140HepG2ZNF622
TMEM177ENSG00000144120.8127.92420198.57370-0.634402.859102.19530K562AKAP8L
TMEM177ENSG00000144120.8202.88840474.93110-1.227005.557404.77580K562AQR
TMEM177ENSG00000144120.8127.30410208.11410-0.709103.081802.15880K562BOP1
TMEM177ENSG00000144120.8314.81680457.03930-0.537804.342603.46910K562EIF2S2
TMEM177ENSG00000144120.8146.46040225.14840-0.620402.701901.85830K562FMR1
TMEM177ENSG00000144120.8101.33570190.83000-0.913104.270703.11180K562FTO
TMEM177ENSG00000144120.8393.06130180.997601.118707.183506.27160K562FXR1
TMEM177ENSG00000144120.8796.24990609.056400.386502.692901.94540K562GRSF1
TMEM177ENSG00000144120.8158.28700269.32260-0.766804.432703.69550K562HNRNPC
TMEM177ENSG00000144120.8434.12460273.678000.665504.183303.02350K562HNRNPM
TMEM177ENSG00000144120.899.64960180.39800-0.856203.236602.21920K562KRR1
TMEM177ENSG00000144120.8248.83280154.307500.689304.063103.03900K562MAGOH
TMEM177ENSG00000144120.8286.77170387.99160-0.436103.101702.31500K562NSUN2
TMEM177ENSG00000144120.8196.38360373.87730-0.928906.854605.54450K562PCBP3
TMEM177ENSG00000144120.8192.94420286.77730-0.571703.136502.28020K562POLR2G
TMEM177ENSG00000144120.8344.04930149.929001.1982012.6889011.32040K562PTBP1
TMEM177ENSG00000144120.879.02340196.97700-1.317707.817806.95120K562PUS1
TMEM177ENSG00000144120.8109.09240191.88600-0.814704.193403.47920K562RBM15
TMEM177ENSG00000144120.8256.40860151.231200.761602.661901.59300K562NELFE
TMEM177ENSG00000144120.8428.14120287.644200.573704.241803.21900K562SYNCRIP
TMEM177ENSG00000144120.8226.15370411.39390-0.863209.290408.06770K562UPF1
TMEM177ENSG00000144120.8115.36290199.66720-0.791402.552701.33100K562UTP18
TMEM177ENSG00000144120.8206.16190352.01980-0.771905.974104.66030K562WDR3
TMEM177ENSG00000144120.8351.92850535.14540-0.604602.238501.47410K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TMEM177 is not available on ENCORE database.





2 RBPs can affect the splicing of TMEM177 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A5SSTMEM177ENSG00000144120.8chr2+1204367421204369641204367421204368011204384071204396940.274000.002730.04372longerK562AQR
A5SSTMEM177ENSG00000144120.8chr2+1204367421204371931204367421204368011204384071204396940.309000.000090.01905longerHepG2TIAL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TMEM177 is not avaliable on ENCORE database.