TBCB

General Information

Gene Name       : TBCB
Gene ID             : ENSG00000105254.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TBCB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TBCBENSG00000105254.1131.5556.8344.19ENCSR000AEF
HepG2TBCBENSG00000105254.11270.56157.27213.92ENCSR985KAT
K562TBCBENSG00000105254.1148.0438.8543.45ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TBCB is not avaliable on ENCORE database.



Proteins bound to RNA
  • TBCB RNA is bound by 15 proteins.  







eCLIP assay for TBCB is not avaliable on ENCORE database.





15 proteins are bound to TBCB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193661161736611699+3'-UTR,CDS,intron-Distal4.067323.14999HepG2GRWD1
chr193661657436616656+3'-UTR,CDS3.149113.03634HepG2PABPN1
chr193661657136616675+3'-UTR,CDS3.068139.08837HepG2LARP4
chr193661668036616766+3'-UTR,CDS3.8647211.49033HepG2LARP4
chr193661161236611681+3'-UTR,CDS,intron-Distal3.116744.16939HepG2PPIG
chr193660639736606564+5'-UTR,CDS3.667986.96255HepG2DDX3X
chr193660677436606928+5'-UTR,intron-Distal,intron-Proximal4.420755.07796HepG2SF3B4
chr193661254336612626+CDS,intron-Distal,intron-Proximal3.786106.98305HepG2PPIG
chr193661635836616421+CDS4.156036.31568HepG2LARP4
chr193661260436612662+CDS,intron-Distal,intron-Proximal3.492044.78164HepG2PRPF8
chr193661636236616426+CDS,intron-Proximal4.573676.08299HepG2PPIG
chr193661246736612537+CDS,intron-Distal3.470444.94718HepG2PPIG
chr193661243236612570+CDS,intron-Distal4.000333.65750K562YBX3
chr193661242836612590+CDS,intron-Distal,intron-Proximal3.754327.11719HepG2RPS3
chr193660649736606559+CDS3.526985.37252K562YBX3
chr193661198236612070+intron-Distal3.378835.63071HepG2AQR
chr193661216336612213+intron-Distal3.978893.25631HepG2PRPF4
chr193661225036612308+intron-Distal5.356636.82887HepG2EFTUD2
chr193661280136612875+intron-Distal3.914666.48632HepG2PRPF4
chr193661195936612092+intron-Distal4.198056.94246HepG2FAM120A
chr193661206336612139+intron-Distal4.755166.57216HepG2PRPF4
chr193661200936612113+intron-Distal4.6293210.92835HepG2PRPF8
chr193661031536610450+intron-Distal4.073323.06084HepG2HNRNPK
chr193661223836612318+intron-Distal4.404673.90256HepG2PRPF4
chr193661266536612770+intron-Distal,intron-Proximal3.110404.70437HepG2RBFOX2
chr193661212736612209+intron-Distal5.219896.62861HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TBCB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TBCB is not available on ENCORE database.

  • 69 RBPs can affect the levels of TBCB.  








The Knockdown/knockout RNA-Seq assay for TBCB is not available on ENCORE database.





69 RBPs can affect the gene expression of TBCB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TBCBENSG00000105254.71604.654101264.094200.344102.325301.60250HepG2ASCC1
TBCBENSG00000105254.71288.43870801.606900.684602.359101.53140HepG2BCLAF1
TBCBENSG00000105254.71272.99040948.777500.424003.849002.40750HepG2BUD13
TBCBENSG00000105254.71491.227501201.005900.312202.042701.37170HepG2CIRBP
TBCBENSG00000105254.7476.43220707.11700-0.569704.333103.48930HepG2CPSF6
TBCBENSG00000105254.71561.866001042.847200.582607.223405.51860HepG2CPSF7
TBCBENSG00000105254.71143.12270781.583000.548402.537301.56610HepG2YBX3
TBCBENSG00000105254.71602.118501346.091000.251102.841602.19150HepG2CELF1
TBCBENSG00000105254.7566.71740848.71920-0.582703.191201.81420HepG2DDX27
TBCBENSG00000105254.72267.185701463.389600.631506.668705.74020HepG2DDX3X
TBCBENSG00000105254.7949.69310692.040900.456504.095502.47380HepG2DDX52
TBCBENSG00000105254.71775.772501257.542400.497702.996602.35590HepG2DDX6
TBCBENSG00000105254.7954.88690760.629100.328002.195001.60170HepG2DNAJC2
TBCBENSG00000105254.71190.363801427.89480-0.262502.346101.56430HepG2EIF4G1
TBCBENSG00000105254.71044.663301367.79130-0.388802.902102.06950HepG2EIF4G2
TBCBENSG00000105254.7591.12060807.70720-0.450402.483901.39660HepG2FASTKD2
TBCBENSG00000105254.7428.09330708.35490-0.726502.625301.63670HepG2FTO
TBCBENSG00000105254.7967.827101250.01140-0.369102.279901.67240HepG2G3BP1
TBCBENSG00000105254.7602.91220801.53800-0.410802.429201.82510HepG2GPKOW
TBCBENSG00000105254.71363.444301044.096500.384905.257903.95760HepG2HDGF
TBCBENSG00000105254.71558.264301330.067700.228302.488901.59620HepG2HNRNPA2B1
TBCBENSG00000105254.71560.567301318.132500.243503.436502.69310HepG2HNRNPL
TBCBENSG00000105254.72168.560701387.647000.644006.819505.84560HepG2NCBP2
TBCBENSG00000105254.71860.767201434.971400.374804.959203.94300HepG2NOL12
TBCBENSG00000105254.7744.115901235.38380-0.731404.529803.61780HepG2PABPC4
TBCBENSG00000105254.71786.451601261.084600.502309.450708.43760HepG2PCBP1
TBCBENSG00000105254.7960.24560763.674700.330302.104001.45400HepG2PPIL4
TBCBENSG00000105254.7441.12460688.98780-0.643307.925906.70400HepG2PRPF4
TBCBENSG00000105254.7967.021401283.21900-0.408105.423104.71170HepG2PTBP1
TBCBENSG00000105254.71797.793101369.878500.392104.250803.53000HepG2PUF60
TBCBENSG00000105254.7835.167801113.93630-0.415505.771304.94080HepG2PUS1
TBCBENSG00000105254.7963.92420668.156800.528603.267502.39950HepG2RPS3A
TBCBENSG00000105254.71852.494701017.060800.865003.369902.62470HepG2SF3A3
TBCBENSG00000105254.71512.007301739.40340-0.202102.311701.84040HepG2SRFBP1
TBCBENSG00000105254.71087.388001394.47050-0.358904.476303.91070HepG2SRSF1
TBCBENSG00000105254.7557.299501134.48750-1.0255026.6208025.23920HepG2SRSF9
TBCBENSG00000105254.7980.828401510.13560-0.6226013.4567012.49600HepG2SSB
TBCBENSG00000105254.7733.546801253.44140-0.7729014.0797012.95980HepG2TAF15
TBCBENSG00000105254.7532.90520745.65610-0.484603.673702.85420HepG2TARDBP
TBCBENSG00000105254.7958.594301151.70270-0.264802.033001.31380HepG2TIA1
TBCBENSG00000105254.7642.15170832.15820-0.373901.940701.50630HepG2TIAL1
TBCBENSG00000105254.71179.03710901.978000.386305.204404.29490HepG2UPF1
TBCBENSG00000105254.71227.20690870.823400.494807.658806.74320HepG2UTP3
TBCBENSG00000105254.7843.21820598.492700.494502.865201.74480HepG2XPO5
TBCBENSG00000105254.71285.65250992.002300.374005.778405.06350HepG2ZNF622
TBCBENSG00000105254.7407.44990313.863800.376402.240201.72060K562AGGF1
TBCBENSG00000105254.7701.58950506.008700.471404.033102.48800K562APOBEC3C
TBCBENSG00000105254.7634.77440347.244200.8702012.6526011.36660K562DDX47
TBCBENSG00000105254.7515.09250413.680300.316202.010401.38040K562EIF2S2
TBCBENSG00000105254.7195.17070132.551700.558102.520001.76020K562EIF3G
TBCBENSG00000105254.7342.36510255.515600.422002.074301.33580K562FIP1L1
TBCBENSG00000105254.7357.20320262.585400.443902.678502.08180K562FXR1
TBCBENSG00000105254.739.39800105.93710-1.427005.253004.20720K562G3BP2
TBCBENSG00000105254.7767.26060551.274200.476803.826802.94220K562GRSF1
TBCBENSG00000105254.7191.04340261.39720-0.452301.949201.43690K562HNRNPC
TBCBENSG00000105254.7561.89170346.399100.697805.807204.66890K562HSPD1
TBCBENSG00000105254.7260.06090171.109800.603802.574001.59670K562IGF2BP2
TBCBENSG00000105254.7136.97980283.06990-1.047206.833305.52530K562PCBP3
TBCBENSG00000105254.7142.15770217.11750-0.611002.931702.10650K562POLR2G
TBCBENSG00000105254.7416.93050290.087400.523203.251002.34940K562PPIG
TBCBENSG00000105254.7483.50650665.46890-0.460803.570802.34870K562PUM1
TBCBENSG00000105254.7232.79730167.302700.476502.063901.34330K562RBM22
TBCBENSG00000105254.7366.64270249.629700.554502.450201.68280K562RPS19
TBCBENSG00000105254.7150.9294084.376800.838902.668201.68550K562RPS3
TBCBENSG00000105254.7260.67190344.09510-0.400602.354501.48200K562SRPK2
TBCBENSG00000105254.7228.72300335.22550-0.551502.860101.47460K562SSRP1
TBCBENSG00000105254.7296.77910217.783900.446402.179401.45000K562SYNCRIP
TBCBENSG00000105254.7264.64320167.062500.663603.412902.48960K562TIA1
TBCBENSG00000105254.763.67480105.98320-0.735002.383701.63820K562U2AF2
TBCBENSG00000105254.7176.88380251.13130-0.505602.260001.34890K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TBCB is not available on ENCORE database.





10 RBPs can affect the splicing of TBCB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETBCBENSG00000105254.7chr19+3661297836613075366124283661262036616352366164250.069000.002630.02749includedK562AQR
SETBCBENSG00000105254.7chr19+3661297836613075366124283661262036616352366164250.081000.000020.00728includedHepG2TIA1
SETBCBENSG00000105254.7chr19+3661297836613075366124283661262036616352366164250.054000.000880.06787includedHepG2DDX6
SETBCBENSG00000105254.7chr19+3661297836613075366124283661262036616352366164250.073000.000010.00125includedHepG2PCBP1
SETBCBENSG00000105254.7chr19+3661297836613075366124283661262036616352366164250.095000.000000.00082includedHepG2FUBP3
RITBCBENSG00000105254.7chr19+3661138336611708366113833661141736611611366117080.114000.002650.03010includedHepG2SF3A3
RITBCBENSG00000105254.7chr19+3661138336611708366113833661141736611611366117080.138000.000310.00342includedHepG2U2AF2
RITBCBENSG00000105254.7chr19+3661138336611708366113833661141736611611366117080.111000.005530.05480includedHepG2NCBP2
RITBCBENSG00000105254.7chr19+3661138336611708366113833661141736611611366117080.121000.002310.01866includedHepG2SF3B4
RITBCBENSG00000105254.7chr19+366113833661170836611383366114173661161136611708-0.116000.002600.09017excludedHepG2LARP4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TBCB is not avaliable on ENCORE database.