SMAD2

General Information

Gene Name : SMAD2
Gene ID : ENSG00000175387.15
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: SMAD2)

Not Available

Antibody Validation

Thermo Fisher: 700048

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	SMAD2	ENSG00000175387.15	66.82	63.35	65.08	ENCSR000AEF
HepG2	SMAD2	ENSG00000175387.15	33.06	42.58	37.82	ENCSR985KAT
K562	SMAD2	ENSG00000175387.15	22.87	22.64	22.76	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	SMAD2-BGKcLV15-K562	ENCSR016WTN	SMAD2	K562	Released		ENCSR404OHQ	CRISPR	KD% = 91.0,91.8
knockdown followed by RNA-seq	SMAD2-BGHcLV16-HepG2	ENCSR036ANR	SMAD2	HepG2	Released		ENCSR964HKT	CRISPR	KD% = 99.6,99.8

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
SMAD2	ENCAB373WLA	700048	TH2627538			Released, ENCODE4	BGHcLV16-51, Released, ENCODE4	BGKcLV15-55, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
SMAD2	K562	CRISPR	ENCSR016WTN	ENCSR404OHQ	SMAD2-BGKcLV15-55,SMAD2-BGKcLV15-56	NT-BGKcLV15-1,NT-BGKcLV15-2	91.0,91.8	Released	ENCODE4
SMAD2	K562	CRISPR			BGKcLV19-45,BGKcLV19-46	BGKcLV19-1,BGKcLV19-2	NO CLEAR BAND ON THE POSITION,	NotSatisfied	ENCODE4
SMAD2	HepG2	CRISPR	ENCSR036ANR	ENCSR964HKT	SMAD2-BGHcLV16-51,SMAD2-BGHcLV16-52	NT-BGHcLV16-1,NT-BGHcLV16-2	99.6,99.8	Released	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
SMAD2	Product_ID: 700048 Lot_ID: TH2627538 Source: Thermo Fisher Target Name: SMAD2-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for SMAD2 is not avaliable on ENCORE database.

Proteins bound to RNA

SMAD2 RNA is bound by 28 proteins.

eCLIP assay for SMAD2 is not avaliable on ENCORE database.

28 proteins are bound to SMAD2 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr18	45368055	45368169	-	3'-UTR,intron-Distal	4.95518	7.81775	K562	IGF2BP1
chr18	45365928	45365991	-	3'-UTR,intron-Distal	3.77127	8.61413	HepG2	QKI
chr18	45423000	45423176	-	3'-UTR,5'-UTR,CDS,intron-Distal	3.32596	7.99106	HepG2	GRWD1
chr18	45359551	45359662	-	3'-UTR,intron-Distal	3.01278	3.11628	K562	KHSRP
chr18	45362433	45362456	-	3'-UTR,intron-Distal	4.18161	4.95438	K562	YBX3
chr18	45366169	45366266	-	3'-UTR,intron-Distal	3.58728	3.35585	HepG2	QKI
chr18	45456739	45456768	-	5'-UTR,intron-Distal,intron-Proximal	3.91029	5.93840	HepG2	PRPF8
chr18	45456889	45456958	-	5'-UTR,intron-Distal,intron-Proximal	5.08441	4.57427	HepG2	PCBP2
chr18	45456559	45456630	-	5'-UTR,intron-Distal	4.54195	9.49243	HepG2	EFTUD2
chr18	45457264	45457350	-	5'-UTR,intron-Distal,intron-Proximal	4.05871	3.41967	HepG2	DDX3X
chr18	45456960	45457021	-	5'-UTR,intron-Distal,intron-Proximal	5.28969	5.21824	HepG2	XRN2
chr18	45456684	45456739	-	5'-UTR,intron-Distal,intron-Proximal	3.82568	10.32093	HepG2	PRPF8
chr18	45456525	45456638	-	5'-UTR,intron-Distal,intron-Proximal	3.51941	7.91537	HepG2	PRPF4
chr18	45456781	45456859	-	5'-UTR,intron-Distal,intron-Proximal	4.07164	3.88460	HepG2	PCBP2
chr18	45394691	45394701	-	CDS,intron-Distal,intron-Proximal	5.28676	5.01842	HepG2	PRPF8
chr18	45395768	45395828	-	CDS,intron-Distal,intron-Proximal	3.95429	3.07225	K562	U2AF1
chr18	45371748	45371819	-	CDS,intron-Distal	3.12407	5.00751	HepG2	BCLAF1
chr18	45395615	45395673	-	CDS,intron-Distal,intron-Proximal	3.68784	3.27569	HepG2	BCLAF1
chr18	45395754	45395846	-	CDS,intron-Distal,intron-Proximal	5.40054	15.60330	HepG2	U2AF2
chr18	45422924	45423000	-	CDS,intron-Distal	3.47183	4.22563	K562	UCHL5
chr18	45422897	45423000	-	CDS,intron-Distal	4.98030	7.86337	HepG2	GRWD1
chr18	45372051	45372138	-	CDS,intron-Distal	3.66958	8.66838	HepG2	BCLAF1
chr18	45395670	45395768	-	CDS,intron-Distal,intron-Proximal	5.01207	8.07779	K562	YBX3
chr18	45375006	45375064	-	CDS,intron-Distal,intron-Proximal	3.19468	6.18258	HepG2	U2AF2
chr18	45394771	45394829	-	CDS,intron-Distal,intron-Proximal	3.77304	3.65750	K562	YBX3
chr18	45422972	45423018	-	CDS,intron-Distal	5.10254	6.37937	HepG2	BCLAF1
chr18	45422910	45422954	-	CDS,intron-Distal	3.91270	3.20743	HepG2	PPIG
chr18	45391440	45391509	-	CDS,intron-Distal,intron-Proximal	3.78864	3.38114	HepG2	GRWD1
chr18	45394712	45394771	-	CDS,intron-Distal	3.31204	4.53005	K562	YBX3
chr18	45374938	45375014	-	CDS,intron-Distal	3.56880	5.15500	HepG2	BCLAF1
chr18	45394644	45394734	-	CDS,intron-Distal,intron-Proximal	4.33466	3.89565	K562	PRPF8
chr18	45395757	45395839	-	CDS,intron-Distal,intron-Proximal	3.59700	5.38969	K562	U2AF2
chr18	45451748	45451813	-	intron-Distal	4.23366	3.60235	HepG2	HNRNPM
chr18	45430637	45430689	-	intron-Distal	3.52908	4.60009	HepG2	SUGP2
chr18	45456295	45456356	-	intron-Distal	3.12961	3.61506	K562	NONO
chr18	45429617	45429648	-	intron-Distal	3.92021	3.39864	HepG2	SUGP2
chr18	45445762	45445830	-	intron-Distal	3.06808	4.63410	HepG2	SUGP2
chr18	45423691	45423752	-	intron-Distal	4.77734	5.95026	HepG2	U2AF2
chr18	45431601	45431645	-	intron-Distal	4.41477	4.53347	HepG2	SUGP2
chr18	45375400	45375467	-	intron-Distal	3.11637	4.05586	HepG2	U2AF2
chr18	45384866	45384933	-	intron-Distal	3.93973	4.06464	HepG2	CSTF2
chr18	45430824	45430892	-	intron-Distal	5.59194	12.35631	HepG2	SUGP2
chr18	45421995	45422119	-	intron-Distal,intron-Proximal	5.45737	9.77283	HepG2	QKI
chr18	45375553	45375668	-	intron-Distal	3.83057	3.71397	K562	KHSRP
chr18	45430291	45430332	-	intron-Distal	3.02908	4.63410	HepG2	SUGP2
chr18	45429463	45429513	-	intron-Distal	4.46501	3.96879	HepG2	MATR3
chr18	45429189	45429243	-	intron-Distal	3.05886	4.67779	HepG2	SUGP2
chr18	45413012	45413073	-	intron-Distal	4.63883	4.05848	HepG2	QKI
chr18	45431053	45431073	-	intron-Distal	3.91477	3.54208	HepG2	SUGP2
chr18	45445128	45445219	-	intron-Distal	4.14856	5.75812	K562	PTBP1
chr18	45394655	45394691	-	intron-Distal,intron-Proximal	5.43131	4.68690	HepG2	PRPF8
chr18	45422632	45422704	-	intron-Distal	4.11949	4.02395	HepG2	KHSRP
chr18	45429305	45429363	-	intron-Distal	4.81095	6.79594	HepG2	MATR3
chr18	45456550	45456616	-	intron-Distal	3.40097	7.46490	HepG2	NKRF
chr18	45429670	45429738	-	intron-Distal	3.19390	5.10681	HepG2	SUGP2
chr18	45421938	45421996	-	intron-Distal	4.27007	4.10688	K562	KHSRP
chr18	45405749	45405928	-	intron-Distal	4.19135	14.11168	K562	AGGF1
chr18	45431362	45431395	-	intron-Distal	4.58298	5.04879	HepG2	SUGP2
chr18	45432260	45432309	-	intron-Distal	3.46575	4.33009	HepG2	SUGP2
chr18	45445671	45445715	-	intron-Distal	4.17444	3.62238	HepG2	MATR3
chr18	45446149	45446268	-	intron-Distal	3.50232	3.64762	HepG2	QKI
chr18	45430763	45430803	-	intron-Distal	4.54065	4.51299	HepG2	SUGP2
chr18	45445651	45445714	-	intron-Distal	4.32878	3.79098	HepG2	SUGP2
chr18	45432431	45432487	-	intron-Distal	3.05354	4.61989	HepG2	SUGP2
chr18	45405804	45405935	-	intron-Distal	4.58448	22.08470	HepG2	HNRNPL
chr18	45444877	45444947	-	intron-Distal	3.31787	5.82512	HepG2	SUGP2
chr18	45456534	45456583	-	intron-Distal	4.13112	7.71647	HepG2	FAM120A
chr18	45429194	45429241	-	intron-Distal	4.74786	5.72657	HepG2	MATR3
chr18	45430932	45430995	-	intron-Distal	3.19531	6.35394	HepG2	SUGP2
chr18	45405800	45405926	-	intron-Distal	4.34123	10.27049	K562	HNRNPL
chr18	45432011	45432042	-	intron-Distal	4.02284	3.63454	HepG2	SUGP2
chr18	45429696	45429762	-	intron-Distal	4.75173	5.37222	HepG2	MATR3
chr18	45456536	45456623	-	intron-Distal	4.24874	3.01090	HepG2	CDC40
chr18	45445520	45445570	-	intron-Distal	3.32570	3.10640	HepG2	SUGP2
chr18	45457033	45457107	-	intron-Distal,intron-Proximal	4.76606	9.23134	HepG2	NKRF
chr18	45429304	45429354	-	intron-Distal	3.41477	3.69184	HepG2	SUGP2
chr18	45431945	45432112	-	intron-Distal	3.25989	5.13070	HepG2	HNRNPM
chr18	45456521	45456623	-	intron-Distal	4.35902	9.31613	HepG2	CSTF2T
chr18	45422707	45422831	-	intron-Distal,intron-Proximal	3.63130	6.18396	K562	KHSRP
chr18	45436455	45436540	-	intron-Distal	3.39912	4.33009	HepG2	SUGP2
chr18	45457021	45457094	-	intron-Distal,intron-Proximal	5.30672	9.47263	HepG2	XRN2
chr18	45445107	45445207	-	intron-Distal	4.42635	9.88335	HepG2	PTBP1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for SMAD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for SMAD2 is not available on ENCORE database.
59 RBPs can affect the levels of SMAD2.

The Knockdown/knockout RNA-Seq assay for SMAD2 is not available on ENCORE database.

59 RBPs can affect the gene expression of SMAD2 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SMAD2	ENSG00000175387.11	1425.21050	1212.86520	0.23270	2.48580	1.90430	HepG2	ACO1
SMAD2	ENSG00000175387.11	857.05610	1147.27160	-0.42070	2.70210	1.77740	HepG2	BCCIP
SMAD2	ENSG00000175387.11	778.37630	996.85600	-0.35690	2.09090	1.30550	HepG2	BCLAF1
SMAD2	ENSG00000175387.11	1243.88320	1692.11190	-0.44400	2.83260	1.84400	HepG2	CCAR1
SMAD2	ENSG00000175387.11	881.66910	1073.42440	-0.28390	2.38980	1.31720	HepG2	DDX1
SMAD2	ENSG00000175387.11	776.68860	1128.02360	-0.53840	4.05810	3.14080	HepG2	DDX55
SMAD2	ENSG00000175387.11	1174.48950	1649.33770	-0.48990	3.48870	2.80200	HepG2	DDX6
SMAD2	ENSG00000175387.11	722.13870	1043.17230	-0.53060	9.19280	8.08510	HepG2	DNAJC2
SMAD2	ENSG00000175387.11	1050.40390	1585.91660	-0.59440	3.85960	3.16600	HepG2	EIF2S1
SMAD2	ENSG00000175387.11	1371.33570	1651.43640	-0.26810	3.28080	2.38380	HepG2	EIF4G1
SMAD2	ENSG00000175387.11	566.27030	721.76910	-0.35000	2.60610	1.47460	HepG2	FAM120A
SMAD2	ENSG00000175387.11	1264.85390	1640.33040	-0.37500	2.19270	1.59730	HepG2	G3BP1
SMAD2	ENSG00000175387.11	802.26830	1062.65970	-0.40550	3.43940	2.72840	HepG2	HNRNPA1
SMAD2	ENSG00000175387.11	1110.67420	1660.32120	-0.58000	4.82130	3.91990	HepG2	HNRNPK
SMAD2	ENSG00000175387.11	1103.57220	1525.01880	-0.46660	9.37670	8.20650	HepG2	HNRNPL
SMAD2	ENSG00000175387.11	725.34560	1174.16410	-0.69490	13.06060	11.82070	HepG2	HNRNPU
SMAD2	ENSG00000175387.11	970.07840	1199.37600	-0.30610	3.83690	2.98760	HepG2	ILF2
SMAD2	ENSG00000175387.11	785.85020	1045.34750	-0.41170	3.65740	2.72930	HepG2	MSI2
SMAD2	ENSG00000175387.11	918.48760	1660.01150	-0.85390	19.03270	17.14760	HepG2	NOL12
SMAD2	ENSG00000175387.11	1445.16460	1663.88000	-0.20330	1.95530	1.43090	HepG2	PCBP1
SMAD2	ENSG00000175387.11	938.67380	1264.10300	-0.42940	2.25960	1.31850	HepG2	PCBP2
SMAD2	ENSG00000175387.11	736.80690	1047.26690	-0.50730	6.53600	5.43930	HepG2	PPIL4
SMAD2	ENSG00000175387.11	1426.84260	1693.07580	-0.24680	2.55510	2.02550	HepG2	PTBP1
SMAD2	ENSG00000175387.11	1226.98040	1682.04070	-0.45510	9.90570	8.92980	HepG2	PUM1
SMAD2	ENSG00000175387.11	1231.47030	1461.96790	-0.24750	2.12690	1.36210	HepG2	RBM15
SMAD2	ENSG00000175387.11	1493.70880	1884.21780	-0.33510	4.43300	3.77700	HepG2	NELFE
SMAD2	ENSG00000175387.11	1515.88030	1754.91640	-0.21120	2.09200	1.54600	HepG2	RECQL
SMAD2	ENSG00000175387.11	725.85750	1045.66660	-0.52670	8.34360	7.31460	HepG2	SAFB2
SMAD2	ENSG00000175387.11	1521.44340	1762.68230	-0.21230	2.07270	1.54970	HepG2	SF3B4
SMAD2	ENSG00000175387.11	968.42120	1219.46020	-0.33250	4.59940	3.80540	HepG2	SMN1
SMAD2	ENSG00000175387.11	1512.93980	1779.29240	-0.23390	3.14030	2.48630	HepG2	SUCLG1
SMAD2	ENSG00000175387.11	772.16440	1141.05690	-0.56340	6.68160	5.96580	HepG2	TIAL1
SMAD2	ENSG00000175387.11	625.04860	1151.11000	-0.88100	20.91260	19.54570	HepG2	TRIM56
SMAD2	ENSG00000175387.11	1429.78770	1104.94210	0.37170	2.63710	2.02250	HepG2	U2AF1
SMAD2	ENSG00000175387.11	1271.02820	1638.44020	-0.36630	2.57600	1.76820	HepG2	UBE2L3
SMAD2	ENSG00000175387.11	878.39080	1281.89290	-0.54530	6.54240	5.54350	HepG2	UPF1
SMAD2	ENSG00000175387.11	969.23140	1237.61480	-0.35260	4.13650	3.42700	HepG2	UTP3
SMAD2	ENSG00000175387.11	798.14310	1105.37630	-0.46980	3.65460	2.83010	HepG2	XRN2
SMAD2	ENSG00000175387.11	1219.24880	1409.83450	-0.20950	2.31270	1.79920	HepG2	ZNF622
SMAD2	ENSG00000175387.11	849.01420	1380.98820	-0.70180	8.51840	7.58040	K562	AQR
SMAD2	ENSG00000175387.11	843.12090	1135.94740	-0.43010	4.72190	3.24860	K562	CPEB4
SMAD2	ENSG00000175387.11	1491.57970	1175.44970	0.34350	4.28040	3.49460	K562	DDX47
SMAD2	ENSG00000175387.11	434.16800	678.23100	-0.64350	5.17750	3.90700	K562	EFTUD2
SMAD2	ENSG00000175387.11	706.34000	527.76640	0.42040	2.58060	1.49870	K562	FKBP4
SMAD2	ENSG00000175387.11	883.60740	1128.97300	-0.35350	2.89380	2.12270	K562	GRSF1
SMAD2	ENSG00000175387.11	767.85890	1062.28050	-0.46830	4.56870	3.17540	K562	HNRNPL
SMAD2	ENSG00000175387.11	831.78760	1110.95040	-0.41750	3.82770	2.83060	K562	MAGOH
SMAD2	ENSG00000175387.11	868.93200	1108.74610	-0.35160	2.97610	2.01490	K562	MATR3
SMAD2	ENSG00000175387.11	659.68530	819.97520	-0.31380	2.75950	1.95160	K562	MTPAP
SMAD2	ENSG00000175387.11	1210.79640	1616.47290	-0.41690	3.79660	2.02540	K562	NOL12
SMAD2	ENSG00000175387.11	761.26590	911.01130	-0.25910	2.41840	1.71600	K562	NSUN2
SMAD2	ENSG00000175387.11	615.43330	948.91780	-0.62470	3.00140	1.70860	K562	PABPC1
SMAD2	ENSG00000175387.11	1183.07650	1518.50680	-0.36010	3.58700	1.95790	K562	PNPT1
SMAD2	ENSG00000175387.11	345.46820	545.15550	-0.65810	5.11160	3.83310	K562	PSIP1
SMAD2	ENSG00000175387.11	1380.75960	1715.02220	-0.31280	3.04240	1.92050	K562	PUM1
SMAD2	ENSG00000175387.11	1356.16700	1680.42640	-0.30930	3.22200	2.18610	K562	PUM2
SMAD2	ENSG00000175387.11	1337.73100	1059.56390	0.33620	2.44320	1.92580	K562	PUS1
SMAD2	ENSG00000175387.11	316.48350	497.33940	-0.65210	5.37940	3.99020	K562	RCC2
SMAD2	ENSG00000175387.11	347.75030	471.46910	-0.43910	2.40770	1.46770	K562	SRFBP1
SMAD2	ENSG00000175387.11	614.92340	1058.07010	-0.78300	11.18700	9.77840	K562	SRSF1
SMAD2	ENSG00000175387.11	727.24360	1070.91480	-0.55830	5.25820	4.26620	K562	TARDBP
SMAD2	ENSG00000175387.11	769.91000	1032.99750	-0.42410	3.95490	2.95240	K562	TIA1
SMAD2	ENSG00000175387.11	361.06100	524.35380	-0.53830	3.29670	2.26950	K562	TIAL1
SMAD2	ENSG00000175387.11	368.90420	557.00860	-0.59450	4.37340	3.12270	K562	TRIM56
SMAD2	ENSG00000175387.11	786.72650	965.96890	-0.29610	2.87360	2.14130	K562	UPF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for SMAD2 is not available on ENCORE database.

16 RBPs can affect the splicing of SMAD2 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.10700	0.00026	0.00694	included	K562	SRSF1
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.21900	0.00000	0.00063	included	K562	FTO
SE	SMAD2	ENSG00000175387.11	chr18	-	45375146	45375351	45374845	45375058	45377644	45377698	0.06400	0.00608	0.08622	included	K562	SF3B4
SE	SMAD2	ENSG00000175387.11	chr18	-	45375146	45375351	45374845	45375058	45377644	45377698	0.17600	0.00000	0.00004	included	K562	PRPF8
SE	SMAD2	ENSG00000175387.11	chr18	-	45396845	45396935	45395613	45395807	45422891	45423180	-0.07900	0.00562	0.08315	excluded	HepG2	U2AF1
SE	SMAD2	ENSG00000175387.11	chr18	-	45456731	45456817	45422891	45423180	45457170	45457208	-0.43800	0.00151	0.02001	excluded	HepG2	U2AF2
SE	SMAD2	ENSG00000175387.11	chr18	-	45421637	45421795	45396843	45396935	45422891	45423182	0.07900	0.00069	0.00894	included	K562	AQR
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.16700	0.00000	0.00000	included	K562	AQR
SE	SMAD2	ENSG00000175387.11	chr18	-	45375270	45375351	45374845	45375058	45377644	45377698	0.20600	0.00000	0.00000	included	K562	AQR
SE	SMAD2	ENSG00000175387.11	chr18	-	45396845	45396935	45395613	45395841	45422891	45423180	-0.08700	0.00852	0.07150	excluded	K562	AQR
SE	SMAD2	ENSG00000175387.11	chr18	-	45396845	45396935	45395613	45395807	45422891	45423180	-0.11600	0.00009	0.00227	excluded	K562	PUS1
SE	SMAD2	ENSG00000175387.11	chr18	-	45375146	45375351	45374845	45375058	45377644	45377698	0.17700	0.00000	0.00008	included	K562	EFTUD2
SE	SMAD2	ENSG00000175387.11	chr18	-	45396845	45396935	45395613	45395807	45422891	45423180	0.09400	0.00003	0.00491	included	HepG2	SUPV3L1
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.11300	0.00034	0.05696	included	K562	SRSF7
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.08300	0.00226	0.06981	included	K562	TARDBP
SE	SMAD2	ENSG00000175387.11	chr18	-	45396845	45396935	45395613	45395807	45422891	45423180	-0.11700	0.00025	0.00911	excluded	K562	RBM15
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.12500	0.00129	0.04965	included	K562	SF3B1
SE	SMAD2	ENSG00000175387.11	chr18	-	45446442	45446540	45422891	45423180	45456731	45456970	0.13000	0.00029	0.04712	included	K562	ZC3H8
SE	SMAD2	ENSG00000175387.11	chr18	-	45394422	45394468	45391429	45391504	45394693	45394828	0.13700	0.00077	0.01541	included	K562	HNRNPC
A3SS	SMAD2	ENSG00000175387.11	chr18	-	45423135	45423303	45423135	45423180	45456731	45456817	0.06100	0.01236	0.06338	longer	K562	AQR
A3SS	SMAD2	ENSG00000175387.11	chr18	-	45395613	45395841	45395613	45395807	45396845	45396935	0.24600	0.00000	0.00000	longer	K562	AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

SMAD2

General Information

Functions

Localization

Domains (AlphaFold: SMAD2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for SMAD2 is not avaliable on ENCORE database.

28 proteins are bound to SMAD2 RNA:

eCLIP assay for SMAD2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for SMAD2 is not available on ENCORE database.

59 RBPs can affect the gene expression of SMAD2 :

The Knockdown/knockout RNA-Seq assay for SMAD2 is not available on ENCORE database.

16 RBPs can affect the splicing of SMAD2 :

The Knockdown/knockout RNA-Seq assay for SMAD2 is not avaliable on ENCORE database.