SIGIRR

General Information

Gene Name       : SIGIRR
Gene ID             : ENSG00000185187.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SIGIRR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SIGIRRENSG00000185187.120.521.140.83ENCSR000AEF
HepG2SIGIRRENSG00000185187.122.640.711.68ENCSR985KAT
K562SIGIRRENSG00000185187.1233.369.9821.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SIGIRR is not avaliable on ENCORE database.



Proteins bound to RNA
  • SIGIRR RNA is bound by 5 proteins.  







eCLIP assay for SIGIRR is not avaliable on ENCORE database.





5 proteins are bound to SIGIRR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11405823405900-3'-UTR,CDS,intron-Distal,intron-Proximal3.051203.43128K562DDX55
chr11405774405938-3'-UTR,CDS,intron-Distal,intron-Proximal5.9249416.54688K562PABPC4
chr11405820405830-3'-UTR,intron-Distal,intron-Proximal4.078297.44026K562YBX3
chr11405995406049-CDS,intron-Distal4.5188810.06857K562RBM15
chr11406313406352-CDS,intron-Distal,intron-Proximal5.0663113.23057K562AQR
chr11406265406313-CDS,intron-Distal,intron-Proximal6.026599.41643K562AQR
chr11405969406036-CDS,intron-Distal3.967563.83925K562YBX3
chr11406029406123-CDS,intron-Distal4.328648.79285K562AQR
chr11406280406340-CDS,intron-Distal,intron-Proximal4.456115.17013K562RBM15
chr11406823406872-CDS,intron-Distal,intron-Proximal4.473894.22893K562RBM15
chr11406079406127-CDS,intron-Distal3.197543.34231K562RBM15
chr11406656406721-intron-Distal4.736936.59918K562RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SIGIRR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SIGIRR is not available on ENCORE database.

  • 75 RBPs can affect the levels of SIGIRR.  








The Knockdown/knockout RNA-Seq assay for SIGIRR is not available on ENCORE database.





75 RBPs can affect the gene expression of SIGIRR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SIGIRRENSG00000185187.867.5429031.073301.120002.932502.22900HepG2AUH
SIGIRRENSG00000185187.862.7961016.799601.902104.565503.29780HepG2CCAR1
SIGIRRENSG00000185187.853.5801017.903301.581402.238001.53590HepG2DDX55
SIGIRRENSG00000185187.855.231409.810302.493007.391906.28680HepG2DNAJC21
SIGIRRENSG00000185187.813.1142040.91910-1.641603.043102.37310HepG2EIF4A3
SIGIRRENSG00000185187.814.4327039.86160-1.465702.163201.55260HepG2EIF4B
SIGIRRENSG00000185187.882.6562013.207902.645609.287008.15870HepG2GPKOW
SIGIRRENSG00000185187.832.3658010.943001.564402.547501.96560HepG2HNRNPU
SIGIRRENSG00000185187.88.8551036.56590-2.045902.438601.52260HepG2IGF2BP3
SIGIRRENSG00000185187.822.391904.546902.299902.633601.35430HepG2ILF3
SIGIRRENSG00000185187.848.9173016.392401.577203.091301.76720HepG2KRR1
SIGIRRENSG00000185187.879.1592021.639101.871007.003306.11140HepG2PUF60
SIGIRRENSG00000185187.81.5546014.19950-3.191302.081401.46240HepG2RAVER1
SIGIRRENSG00000185187.821.602604.697402.201202.465301.70890HepG2RPS3A
SIGIRRENSG00000185187.812.9793033.22480-1.356002.152001.65300HepG2SRSF9
SIGIRRENSG00000185187.8172.7464029.238702.5626021.8157020.67530HepG2SSB
SIGIRRENSG00000185187.86.8246036.71220-2.427404.477703.79040HepG2TAF15
SIGIRRENSG00000185187.850.0513016.061601.639702.399601.40620HepG2TBRG4
SIGIRRENSG00000185187.839.1164010.636701.878603.633603.07710HepG2TIAL1
SIGIRRENSG00000185187.82.7838020.41030-2.874103.156102.48820HepG2U2AF1
SIGIRRENSG00000185187.8360.48680250.681800.524002.866801.61710K562ABCF1
SIGIRRENSG00000185187.8808.93480317.304501.3501030.4851028.68630K562AGGF1
SIGIRRENSG00000185187.8424.97310286.770100.567404.830502.79650K562AKAP1
SIGIRRENSG00000185187.8633.77440348.674400.862009.872807.72020K562AKAP8
SIGIRRENSG00000185187.81009.98520330.170901.612907.424806.31070K562AKAP8L
SIGIRRENSG00000185187.8533.06230346.430900.621606.136404.70670K562ATP5C1
SIGIRRENSG00000185187.8408.08080172.079501.2457015.5413013.22840K562BCLAF1
SIGIRRENSG00000185187.8208.78250111.372900.906505.017103.30430K562CIRBP
SIGIRRENSG00000185187.8494.93180349.184300.503104.001302.65820K562CPEB4
SIGIRRENSG00000185187.8267.07450130.547901.032607.538105.66610K562CSTF2
SIGIRRENSG00000185187.8490.14010290.567800.754207.185405.40550K562DDX3X
SIGIRRENSG00000185187.8465.72330294.596000.660606.215303.99710K562DDX6
SIGIRRENSG00000185187.8212.45730120.131800.822502.267001.44100K562EFTUD2
SIGIRRENSG00000185187.8435.16140319.158300.447202.424701.30550K562EIF2S1
SIGIRRENSG00000185187.8105.14560199.37050-0.923102.573001.60580K562EIF3A
SIGIRRENSG00000185187.8397.99160273.379000.541704.200202.72710K562EIF4B
SIGIRRENSG00000185187.8377.05270180.241201.064709.836908.12860K562FIP1L1
SIGIRRENSG00000185187.8215.76020315.69930-0.549103.333002.67760K562FXR1
SIGIRRENSG00000185187.82.7900031.54580-3.499105.829304.71710K562G3BP2
SIGIRRENSG00000185187.8819.60120422.425600.956105.930904.82100K562GRSF1
SIGIRRENSG00000185187.8605.16350299.209401.016105.285603.41210K562HNRNPA2B1
SIGIRRENSG00000185187.8398.15050104.045701.936003.005601.92090K562IGF2BP2
SIGIRRENSG00000185187.8216.22490105.774901.031406.290704.38040K562IGF2BP3
SIGIRRENSG00000185187.8587.73020350.389800.746105.015003.83960K562KIF1C
SIGIRRENSG00000185187.8215.01910109.215200.977206.323305.03090K562MAGOH
SIGIRRENSG00000185187.8517.54440335.412500.625604.563303.07900K562MAK16
SIGIRRENSG00000185187.8232.91920108.973501.095806.678105.16010K562MATR3
SIGIRRENSG00000185187.8611.20820392.525700.638805.995304.56150K562MBNL1
SIGIRRENSG00000185187.8233.87600131.899900.826204.543903.40270K562METAP2
SIGIRRENSG00000185187.8406.23840275.132400.562102.644301.78550K562NAA15
SIGIRRENSG00000185187.8262.56970118.634601.146102.966901.61310K562NONO
SIGIRRENSG00000185187.8716.22340261.765401.4520010.051107.75430K562PABPN1
SIGIRRENSG00000185187.8175.61510106.820200.717103.331201.84390K562PCBP1
SIGIRRENSG00000185187.8186.37730261.47640-0.488502.221901.50400K562POLR2G
SIGIRRENSG00000185187.8492.60740204.643001.267207.438905.95500K562PPIG
SIGIRRENSG00000185187.8554.74940311.251300.833703.489601.78670K562PPP1R8
SIGIRRENSG00000185187.8191.11870106.119400.848704.741003.89380K562PTBP1
SIGIRRENSG00000185187.8761.59270327.430801.2177016.4446015.15980K562PUS1
SIGIRRENSG00000185187.8785.32820319.038701.2995010.759409.61340K562RBM15
SIGIRRENSG00000185187.8162.91680101.683300.680002.822401.97390K562RBM22
SIGIRRENSG00000185187.872.2535032.765301.140803.366102.42140K562SF3B4
SIGIRRENSG00000185187.8486.85550291.909200.737902.715701.43180K562SFPQ
SIGIRRENSG00000185187.8224.28210116.841400.940703.120801.37660K562SRP68
SIGIRRENSG00000185187.8186.47250104.047300.841603.527602.73650K562SRSF1
SIGIRRENSG00000185187.8273.89120132.134901.051506.805505.03160K562SRSF4
SIGIRRENSG00000185187.8262.6761098.301701.4179012.3966010.02020K562SRSF5
SIGIRRENSG00000185187.8203.63160113.048200.848902.213501.31070K562SUPV3L1
SIGIRRENSG00000185187.8149.62250262.27620-0.809805.311604.16540K562SYNCRIP
SIGIRRENSG00000185187.8250.75330105.270501.252109.481308.05060K562TARDBP
SIGIRRENSG00000185187.8302.34550101.553701.5739013.5826011.64780K562TIA1
SIGIRRENSG00000185187.8258.1479099.730401.372003.184902.00050K562TRA2A
SIGIRRENSG00000185187.8746.95640554.276800.430304.262902.68660K562TROVE2
SIGIRRENSG00000185187.8258.76630119.718101.111902.602601.61880K562UCHL5
SIGIRRENSG00000185187.8643.30120331.988900.954305.553403.53670K562UTP18
SIGIRRENSG00000185187.8281.93830418.17870-0.568704.907803.80940K562WDR43
SIGIRRENSG00000185187.8261.16220122.017701.097803.335601.96930K562XRN2
SIGIRRENSG00000185187.8769.29260559.485300.459303.731302.70110K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SIGIRR is not available on ENCORE database.





6 RBPs can affect the splicing of SIGIRR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESIGIRRENSG00000185187.8chr11-406842406993406348406538407061407164-0.283000.000000.00025excludedK562XRCC6
SESIGIRRENSG00000185187.8chr11-406348406538405715406059407061407135-0.077000.000050.00101excludedK562AQR
SESIGIRRENSG00000185187.8chr11-406842406993406348406538407061407164-0.306000.000000.00006excludedK562FXR1
SESIGIRRENSG00000185187.8chr11-4068424069934063484065384070614071640.194000.001280.07635includedK562HNRNPUL1
SESIGIRRENSG00000185187.8chr11-4068424069934063484065384070614071640.272000.000000.00123includedK562NPM1
A5SSSIGIRRENSG00000185187.8chr11-406348407164407061407164405715406059-0.125000.000060.00172shorterK562AQR
MXESIGIRRENSG00000185187.8chr11-406348406595406842406993405715406059407061407164-0.127000.012900.077852includedK562AQR
MXESIGIRRENSG00000185187.8chr11-406348406513406842406993405715406059407061407164-0.130000.012020.073422includedK562AQR
MXESIGIRRENSG00000185187.8chr11-4080724082064086944088934078164079574098674100270.471000.000670.092181includedHepG2DKC1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SIGIRR is not avaliable on ENCORE database.