SEC23B

General Information

Gene Name       : SEC23B
Gene ID             : ENSG00000101310.16
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SEC23B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SEC23BENSG00000101310.1659.3553.0156.18ENCSR000AEF
HepG2SEC23BENSG00000101310.1696.7597.3397.04ENCSR985KAT
K562SEC23BENSG00000101310.1631.9633.7032.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
SEC23BRibo-STAMP-293TshRNASEC23B-BGRSLV06-37,SEC23B-BGRSLV06-38NT-BGRSLV06-1,NT-BGRSLV06-2,SubmittedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SEC23B is not avaliable on ENCORE database.



Proteins bound to RNA
  • SEC23B RNA is bound by 19 proteins.  







eCLIP assay for SEC23B is not avaliable on ENCORE database.





19 proteins are bound to SEC23B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr201854153518541655+3'-UTR5.7239913.46643K562TIA1
chr201854153218541610+3'-UTR4.429474.89025HepG2DDX55
chr201854158518541686+3'-UTR5.876199.71079HepG2SUB1
chr201854154918541636+3'-UTR4.694444.66293HepG2TIA1
chr201854136318541411+3'-UTR,CDS4.082724.21087HepG2GRWD1
chr201848855218488635+5'-UTR,intron-Distal,intron-Proximal3.805545.22400HepG2DDX3X
chr201849146518491518+5'-UTR,CDS,intron-Proximal3.306113.95805K562DDX3X
chr201848869118488788+5'-UTR,intron-Distal,intron-Proximal4.271675.34865HepG2EFTUD2
chr201848857018488635+5'-UTR,intron-Distal,intron-Proximal3.746464.46401K562DDX3X
chr201849286918492878+CDS4.136093.06595HepG2BCLAF1
chr201854124318541317+CDS,intron-Proximal4.493206.59856K562SF3B4
chr201849160418491660+CDS3.384185.27398HepG2G3BP1
chr201849627018496354+CDS,intron-Proximal4.254963.70678K562BUD13
chr201850507418505164+CDS,intron-Proximal3.471213.81692HepG2LIN28B
chr201849165818491699+CDS4.404327.16838HepG2BCLAF1
chr201850704418507099+CDS3.220395.00751HepG2BCLAF1
chr201850557918505628+CDS4.687604.25741HepG2G3BP1
chr201849160718491687+CDS3.570785.60389HepG2PPIG
chr201850521018505306+CDS5.3690011.05779HepG2G3BP1
chr201850711618507168+CDS3.782477.28307HepG2BCLAF1
chr201850506218505131+CDS,intron-Proximal3.120214.89521HepG2U2AF2
chr201851330818513381+CDS3.135665.41373HepG2PPIG
chr201850712218507174+CDS4.656345.50717HepG2G3BP1
chr201852925218529376+CDS,intron-Proximal3.750015.73713K562IGF2BP1
chr201849153618491579+CDS3.430963.93645HepG2PPIG
chr201852362218523679+CDS,intron-Proximal3.798783.05889HepG2SF3B4
chr201851627118516329+CDS,intron-Proximal3.6283013.46566HepG2U2AF2
chr201853173418531754+CDS,intron-Distal3.160453.24162HepG2G3BP1
chr201850813918508184+CDS,intron-Proximal3.359826.74947HepG2BCLAF1
chr201852293918522976+CDS,intron-Proximal4.579204.25741HepG2G3BP1
chr201851141518511447+CDS3.469145.76104HepG2BCLAF1
chr201851330718513349+CDS,intron-Proximal3.716857.23562HepG2BCLAF1
chr201850704418507088+CDS3.200325.49938HepG2G3BP1
chr201853971718539801+intron-Distal3.958506.26907HepG2SUGP2
chr201853878618538854+intron-Distal3.183803.46325HepG2SUGP2
chr201853164618531719+intron-Distal,intron-Proximal4.281984.57682HepG2SF3B4
chr201852818418528245+intron-Distal3.748563.17235HepG2HNRNPK
chr201853906718539120+intron-Distal4.270764.05620HepG2MATR3
chr201851607318516155+intron-Distal3.958523.48768HepG2KHSRP
chr201851876118518837+intron-Distal3.700783.38413HepG2HNRNPC
chr201853972518539796+intron-Distal4.507734.60209HepG2MATR3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SEC23B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SEC23B is not available on ENCORE database.

  • 81 RBPs can affect the levels of SEC23B.  








The Knockdown/knockout RNA-Seq assay for SEC23B is not available on ENCORE database.





81 RBPs can affect the gene expression of SEC23B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SEC23BENSG00000101310.102836.137102228.786600.347606.775505.90960HepG2ACO1
SEC23BENSG00000101310.101595.703702151.77910-0.431304.007602.83350HepG2ADAR
SEC23BENSG00000101310.104410.770502826.080100.642106.886506.08890HepG2AKAP1
SEC23BENSG00000101310.103997.675603378.476100.242703.465702.71260HepG2AUH
SEC23BENSG00000101310.103584.597302617.518800.453505.414204.61150HepG2BOP1
SEC23BENSG00000101310.103063.415402260.634400.438306.114605.02340HepG2CALR
SEC23BENSG00000101310.102938.900702221.603500.403603.671902.79020HepG2CIRBP
SEC23BENSG00000101310.103410.680301744.177500.967409.188807.82420HepG2CNOT7
SEC23BENSG00000101310.101545.144902403.02770-0.637108.420707.27590HepG2CPSF6
SEC23BENSG00000101310.103076.671802206.621600.479408.939607.14130HepG2YBX3
SEC23BENSG00000101310.103984.021803014.116400.402407.849406.87010HepG2CELF1
SEC23BENSG00000101310.101827.999703240.78990-0.8261037.7986035.68720HepG2DAZAP1
SEC23BENSG00000101310.102331.465502061.214800.177602.130001.39070HepG2DDX19B
SEC23BENSG00000101310.102513.182502070.098800.279702.277401.65420HepG2DDX21
SEC23BENSG00000101310.104268.520102707.224600.656808.302207.26830HepG2DDX3X
SEC23BENSG00000101310.101828.363902147.60370-0.232203.357502.65190HepG2DNAJC2
SEC23BENSG00000101310.102009.090601614.078800.315702.338601.32210HepG2EFTUD2
SEC23BENSG00000101310.102521.768001571.736200.682008.803307.28270HepG2EIF3D
SEC23BENSG00000101310.103186.187502470.687000.366802.538801.92550HepG2EIF4A3
SEC23BENSG00000101310.103433.651202405.444700.513303.699602.90990HepG2EIF4B
SEC23BENSG00000101310.102784.004802177.742200.354203.852602.86730HepG2EWSR1
SEC23BENSG00000101310.102413.531101972.643400.290902.545401.44390HepG2FASTKD2
SEC23BENSG00000101310.101623.891302376.16490-0.549203.855702.54020HepG2FUS
SEC23BENSG00000101310.101899.068002454.76370-0.370303.004002.07510HepG2G3BP2
SEC23BENSG00000101310.102562.289903541.49950-0.466908.887907.69550HepG2HNRNPF
SEC23BENSG00000101310.102559.887702952.07360-0.205603.046102.34100HepG2HNRNPL
SEC23BENSG00000101310.101914.892302417.09760-0.336005.445204.61660HepG2HNRNPU
SEC23BENSG00000101310.102657.925903487.36670-0.391805.207304.24650HepG2IGF2BP1
SEC23BENSG00000101310.103072.271702350.520100.386203.378402.63830HepG2IGF2BP2
SEC23BENSG00000101310.101218.465401661.71170-0.447603.002001.75160HepG2KHDRBS1
SEC23BENSG00000101310.101706.996302037.26390-0.255203.799302.60540HepG2KIF1C
SEC23BENSG00000101310.101761.737702651.22530-0.589703.973002.80200HepG2MTPAP
SEC23BENSG00000101310.103275.435302566.580900.351702.666202.04320HepG2NCBP2
SEC23BENSG00000101310.103179.047202044.671600.636605.127603.17900HepG2NKRF
SEC23BENSG00000101310.102665.735603213.56730-0.269602.946302.15940HepG2NOL12
SEC23BENSG00000101310.101522.541902305.02660-0.598307.628806.42770HepG2NSUN2
SEC23BENSG00000101310.101764.124502392.51330-0.439608.296406.95540HepG2PARN
SEC23BENSG00000101310.102910.983702381.346500.289604.197403.47740HepG2PCBP1
SEC23BENSG00000101310.101526.440202155.85800-0.498108.631407.37890HepG2PPIL4
SEC23BENSG00000101310.101526.514602292.99500-0.5870013.6511012.13190HepG2PRPF4
SEC23BENSG00000101310.102870.293302423.099400.244203.417502.82320HepG2PTBP1
SEC23BENSG00000101310.103860.437103256.503300.245305.004504.25460HepG2PUM1
SEC23BENSG00000101310.104005.331403254.099400.299603.661202.89500HepG2PUM2
SEC23BENSG00000101310.102705.357902270.133900.252903.772703.07650HepG2PUS1
SEC23BENSG00000101310.103240.066302624.297100.304003.706903.00010HepG2QKI
SEC23BENSG00000101310.101255.754102170.74250-0.789605.328604.36760HepG2RAVER1
SEC23BENSG00000101310.102119.296902858.93730-0.431906.165704.94870HepG2RBM15
SEC23BENSG00000101310.103765.297103242.080000.215702.568902.06470HepG2RBM22
SEC23BENSG00000101310.101763.476902275.25670-0.367603.183702.11590HepG2RBM27
SEC23BENSG00000101310.102120.121602511.58110-0.244403.150502.49830HepG2RECQL
SEC23BENSG00000101310.102601.322403815.05280-0.552507.888506.82700HepG2RPLP0
SEC23BENSG00000101310.101871.838201529.383800.291402.503301.91600HepG2RPS19
SEC23BENSG00000101310.104025.213502152.532500.9029045.9415043.81830HepG2SAFB2
SEC23BENSG00000101310.102232.571002522.77660-0.176301.875101.37220HepG2SF3B4
SEC23BENSG00000101310.102560.846702941.49650-0.199902.779202.07600HepG2SLBP
SEC23BENSG00000101310.102962.216602510.217000.238804.210903.44700HepG2SMN1
SEC23BENSG00000101310.101912.549903661.80900-0.9371044.7735043.39510HepG2SRFBP1
SEC23BENSG00000101310.104296.025602633.225500.7061026.6484025.50980HepG2SRSF1
SEC23BENSG00000101310.102789.115603479.40400-0.319005.453504.53240HepG2SRSF7
SEC23BENSG00000101310.103856.653503444.676900.162902.302401.72500HepG2SUCLG1
SEC23BENSG00000101310.101272.938002366.82620-0.8948025.4002023.93390HepG2TAF15
SEC23BENSG00000101310.103176.970502271.701400.483805.344004.48690HepG2U2AF1
SEC23BENSG00000101310.101057.540001430.30390-0.435603.298702.47220HepG2UCHL5
SEC23BENSG00000101310.103044.049402635.374700.207902.793102.09080HepG2UPF1
SEC23BENSG00000101310.101503.242602383.33200-0.664907.537706.35420HepG2XRN2
SEC23BENSG00000101310.101915.647502262.91430-0.240303.510602.76790HepG2ZC3H8
SEC23BENSG00000101310.101525.321401871.18410-0.294802.118101.59180K562AQR
SEC23BENSG00000101310.10566.44200740.55810-0.386702.531601.53230K562CCAR1
SEC23BENSG00000101310.102146.658602692.76410-0.327003.569402.20340K562CCDC124
SEC23BENSG00000101310.102216.500101688.545400.392406.670005.72220K562DDX47
SEC23BENSG00000101310.102916.386302522.967400.209002.270101.48770K562DKC1
SEC23BENSG00000101310.101680.705101378.531300.285803.086102.33350K562EIF2S2
SEC23BENSG00000101310.102054.558302457.66090-0.258502.629201.71120K562EIF4G2
SEC23BENSG00000101310.101390.224101837.00390-0.402004.280503.34400K562GRSF1
SEC23BENSG00000101310.10786.379501116.45240-0.505605.172104.37870K562HNRNPC
SEC23BENSG00000101310.102425.273001646.399700.558707.003205.74830K562HSPD1
SEC23BENSG00000101310.101142.557801415.50900-0.309102.630101.73170K562MATR3
SEC23BENSG00000101310.101281.173201507.19720-0.234402.918202.15540K562NSUN2
SEC23BENSG00000101310.102293.965701469.792400.642102.967101.93140K562PABPN1
SEC23BENSG00000101310.102297.114702794.61250-0.282803.290002.24220K562PUM2
SEC23BENSG00000101310.102880.399902325.205400.308802.530602.00600K562PUS1
SEC23BENSG00000101310.101057.449301321.36620-0.321402.414001.63220K562RBM22
SEC23BENSG00000101310.101185.31910913.411300.375803.419002.31990K562RCC2
SEC23BENSG00000101310.101684.44580952.485500.822409.748208.20080K562RPS19
SEC23BENSG00000101310.101232.917001487.31380-0.270602.509201.73000K562SF3A3
SEC23BENSG00000101310.10967.630801178.85380-0.284902.344301.55870K562SF3B4
SEC23BENSG00000101310.101075.203001422.04700-0.403404.069203.05740K562WDR43
SEC23BENSG00000101310.10759.37800975.81240-0.361802.414201.31000K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SEC23B is not available on ENCORE database.





3 RBPs can affect the splicing of SEC23B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESEC23BENSG00000101310.10chr20+185317321853181918529252185294141853487818535034-0.098000.000080.00141excludedK562AQR
SESEC23BENSG00000101310.10chr20+185229391852304618516296185163861852366218523816-0.082000.000010.00024excludedK562AQR
SESEC23BENSG00000101310.10chr20+184887341848894118488222184886341849146518491700-0.128000.000190.02050excludedK562SUPV3L1
SESEC23BENSG00000101310.10chr20+1853173218531819185292521852941418534878185350340.164000.000620.08816includedK562FXR2
A3SSSEC23BENSG00000101310.10chr20+1849145318491700184914651849170018488222184886340.093000.005380.03082longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SEC23B is not avaliable on ENCORE database.