RAP1A

General Information

Gene Name       : RAP1A
Gene ID             : ENSG00000116473.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: RAP1A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878RAP1AENSG00000116473.14163.28145.23154.25ENCSR000AEF
HepG2RAP1AENSG00000116473.1419.3840.6230.00ENCSR985KAT
K562RAP1AENSG00000116473.1449.6757.9853.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for RAP1A is not avaliable on ENCORE database.



Proteins bound to RNA
  • RAP1A RNA is bound by 19 proteins.  







eCLIP assay for RAP1A is not avaliable on ENCORE database.





19 proteins are bound to RAP1A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1112233955112233985+3'-UTR,CDS,intron-Proximal3.267364.11552K562FTO
chr1112255146112255212+3'-UTR3.569254.43122HepG2SUB1
chr1112233954112233976+3'-UTR,intron-Proximal3.496854.40383K562UCHL5
chr1112233976112234047+3'-UTR,CDS,intron-Proximal3.913305.42720K562UCHL5
chr1112255146112255253+3'-UTR3.6788814.02720K562PUM2
chr1112255375112255434+3'-UTR3.985883.97054K562IGF2BP1
chr1112233955112234013+3'-UTR,CDS,intron-Proximal3.6855112.00587K562DDX3X
chr1112233954112233976+3'-UTR,intron-Proximal3.202103.02345K562ZNF622
chr1112162527112162629+5'-UTR,intron-Distal,intron-Proximal3.149046.65473K562CSTF2T
chr1112162710112162779+5'-UTR,intron-Distal3.276453.73797K562CSTF2T
chr1112162408112162486+5'-UTR,intron-Distal3.995374.26442K562DDX3X
chr1112162522112162558+5'-UTR,intron-Distal,intron-Proximal4.026409.77030K562DDX3X
chr1112162517112162561+5'-UTR,intron-Distal,intron-Proximal3.210424.28285K562FTO
chr1112162552112162621+5'-UTR,intron-Distal,intron-Proximal4.237143.03048HepG2GTF2F1
chr1112240048112240102+CDS,intron-Proximal3.610344.21358HepG2U2AF2
chr1112240048112240097+CDS,intron-Proximal4.066776.63197K562U2AF1
chr1112240058112240096+CDS,intron-Proximal4.5891113.26717K562U2AF2
chr1112190844112190932+intron-Distal3.244246.35394HepG2SUGP2
chr1112214755112214822+intron-Distal3.578403.02234K562KHSRP
chr1112191270112191367+intron-Distal4.182238.18586HepG2SUGP2
chr1112231916112232017+intron-Distal5.453598.42544K562PTBP1
chr1112168419112168487+intron-Distal6.1166516.83057HepG2PTBP1
chr1112220565112220686+intron-Distal3.547558.47371K562KHSRP
chr1112163063112163139+intron-Distal,intron-Proximal3.158354.12564K562CSTF2T
chr1112238054112238177+intron-Distal,intron-Proximal3.614715.35459K562KHSRP
chr1112191090112191182+intron-Distal4.258808.81208HepG2SUGP2
chr1112203092112203181+intron-Distal4.254853.72005K562MATR3
chr1112163079112163131+intron-Distal3.859703.03048HepG2GTF2F1
chr1112168423112168487+intron-Distal6.6665316.14543K562PTBP1
chr1112163327112163372+intron-Distal3.938573.77503K562TIA1
chr1112168385112168423+intron-Distal4.778509.03914K562PTBP1
chr1112186401112186470+intron-Distal3.114913.17661HepG2HNRNPL
chr1112191975112192015+intron-Distal3.025973.23296HepG2SUGP2
chr1112162560112162647+intron-Distal,intron-Proximal4.387894.79286HepG2PRPF4
chr1112220906112220979+intron-Distal3.105963.48890K562KHSRP
chr1112220732112220810+intron-Distal4.017773.90026K562KHSRP
chr1112231914112232000+intron-Distal5.100488.14620HepG2PTBP1
chr1112220822112220919+intron-Distal5.334875.61339K562QKI
chr1112240048112240058+intron-Proximal5.4815913.37136K562U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for RAP1A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for RAP1A is not available on ENCORE database.

  • 80 RBPs can affect the levels of RAP1A.  








The Knockdown/knockout RNA-Seq assay for RAP1A is not available on ENCORE database.





80 RBPs can affect the gene expression of RAP1A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
RAP1AENSG00000116473.10786.69320515.535400.609606.545505.42510HepG2CALR
RAP1AENSG00000116473.10512.38750890.62200-0.797606.543405.02470HepG2CCAR1
RAP1AENSG00000116473.10439.61210609.48110-0.471402.023701.37510HepG2CNOT7
RAP1AENSG00000116473.10318.31830468.29560-0.556903.459702.69840HepG2CPSF6
RAP1AENSG00000116473.10605.11870817.33000-0.433704.057403.30650HepG2CELF1
RAP1AENSG00000116473.10695.03780879.05820-0.338902.726201.98980HepG2DAZAP1
RAP1AENSG00000116473.10788.28940475.201700.730107.705206.63100HepG2DDX21
RAP1AENSG00000116473.10619.51150464.808300.414402.844801.91590HepG2DDX24
RAP1AENSG00000116473.10656.41760515.082900.349702.782502.10370HepG2DKC1
RAP1AENSG00000116473.10359.22670546.24760-0.604705.927904.93080HepG2DNAJC21
RAP1AENSG00000116473.10413.70290541.34610-0.388003.235502.53990HepG2DNAJC2
RAP1AENSG00000116473.10332.73170873.63570-1.3927020.2803018.77290HepG2EIF2S1
RAP1AENSG00000116473.10523.75690965.53290-0.882408.942507.79850HepG2EIF4A3
RAP1AENSG00000116473.10714.542301000.88370-0.486205.808004.99020HepG2ETF1
RAP1AENSG00000116473.10510.81450903.62060-0.822908.177907.06560HepG2G3BP1
RAP1AENSG00000116473.10322.48440613.39360-0.927609.734008.49970HepG2HNRNPC
RAP1AENSG00000116473.10451.81160571.20530-0.338301.960101.34920HepG2HNRNPF
RAP1AENSG00000116473.10657.18490914.76430-0.477103.675902.88010HepG2HNRNPK
RAP1AENSG00000116473.10610.09160800.82380-0.392503.121102.40790HepG2HNRNPL
RAP1AENSG00000116473.10449.58580609.34010-0.438704.133403.40380HepG2HNRNPU
RAP1AENSG00000116473.10438.89430562.47780-0.357902.194301.54480HepG2IGF2BP1
RAP1AENSG00000116473.10654.53010918.54610-0.488903.529802.77700HepG2IGF2BP2
RAP1AENSG00000116473.10504.28470622.42520-0.303702.593401.88160HepG2ILF2
RAP1AENSG00000116473.10479.08900923.83390-0.947308.718606.85500HepG2KHSRP
RAP1AENSG00000116473.10680.95240508.480000.421303.325202.44150HepG2MSI2
RAP1AENSG00000116473.10700.971101002.92080-0.516803.763103.02840HepG2NCBP2
RAP1AENSG00000116473.10637.36290893.28180-0.487003.451202.65090HepG2PABPC4
RAP1AENSG00000116473.10413.48020603.17470-0.544805.599304.45340HepG2PARN
RAP1AENSG00000116473.10655.59370797.77490-0.283202.314801.74950HepG2PCBP1
RAP1AENSG00000116473.10440.39650543.48720-0.303401.966501.33630HepG2PPIL4
RAP1AENSG00000116473.10705.15920450.371500.646705.553404.45110HepG2PRPF8
RAP1AENSG00000116473.10662.06440811.76060-0.294102.576802.04590HepG2PTBP1
RAP1AENSG00000116473.10638.62110879.16790-0.461204.531503.75910HepG2QKI
RAP1AENSG00000116473.101087.49290590.796400.880205.844104.84540HepG2RAVER1
RAP1AENSG00000116473.10586.41640836.55810-0.512505.668404.99370HepG2RBM22
RAP1AENSG00000116473.10655.14870841.40130-0.361001.880701.35890HepG2RECQL
RAP1AENSG00000116473.10251.85940378.74390-0.588603.063802.42110HepG2RPS19
RAP1AENSG00000116473.10435.83110542.65950-0.316302.066201.49650HepG2SAFB2
RAP1AENSG00000116473.101069.91210590.366800.857706.921905.82200HepG2SF3A3
RAP1AENSG00000116473.10581.18310797.61840-0.456703.525702.74930HepG2SLBP
RAP1AENSG00000116473.10434.97720632.85840-0.540905.807304.93030HepG2SMN1
RAP1AENSG00000116473.101106.38540944.869600.227602.226801.76190HepG2SRFBP1
RAP1AENSG00000116473.101127.58780882.157000.354003.761203.23140HepG2SRSF1
RAP1AENSG00000116473.10575.87190821.40260-0.512304.157903.41900HepG2SRSF5
RAP1AENSG00000116473.10424.04100561.17780-0.404303.139002.40360HepG2SRSF7
RAP1AENSG00000116473.10995.90060820.384400.279602.686402.17850HepG2SSB
RAP1AENSG00000116473.10312.88780548.27140-0.809203.101101.69290HepG2SUGP2
RAP1AENSG00000116473.10755.27690581.019600.378302.335701.70740HepG2SUPV3L1
RAP1AENSG00000116473.10442.72710592.18470-0.419603.202002.67020HepG2TIAL1
RAP1AENSG00000116473.10474.55150597.37430-0.332102.340601.81330HepG2TRIM56
RAP1AENSG00000116473.10413.99400538.16900-0.378402.491001.48890HepG2UTP18
RAP1AENSG00000116473.10838.63660575.822200.542308.100707.29290HepG2ZNF622
RAP1AENSG00000116473.101319.949201007.375600.389803.370002.05150K562AARS
RAP1AENSG00000116473.102048.971101361.475600.5896013.0128011.88030K562AGGF1
RAP1AENSG00000116473.101910.794801416.664800.431604.406503.57600K562AKAP8L
RAP1AENSG00000116473.10299.04680534.13170-0.836802.355701.39860K562CCAR1
RAP1AENSG00000116473.102044.293001627.078100.329203.466602.12720K562CCDC124
RAP1AENSG00000116473.10917.656101210.19440-0.399203.876702.94930K562CPSF6
RAP1AENSG00000116473.101989.499101524.510100.384005.279304.01660K562DKC1
RAP1AENSG00000116473.10849.499901256.27000-0.564509.267006.99790K562EIF2S1
RAP1AENSG00000116473.10289.49630543.34020-0.908302.971101.92540K562EIF3A
RAP1AENSG00000116473.10918.091001173.67340-0.354303.519302.62830K562EIF3G
RAP1AENSG00000116473.10760.520601194.88070-0.651807.874706.49080K562EIF4A3
RAP1AENSG00000116473.101844.972101383.590700.415102.602001.91980K562G3BP2
RAP1AENSG00000116473.10718.766101155.45640-0.684908.496007.09550K562GPKOW
RAP1AENSG00000116473.10713.155501102.17390-0.628107.432006.49930K562HNRNPC
RAP1AENSG00000116473.102286.634001719.950600.410803.554502.13540K562HNRNPK
RAP1AENSG00000116473.101014.235101741.38290-0.779809.205306.08810K562KHSRP
RAP1AENSG00000116473.10825.771401117.94630-0.437003.396701.73590K562LIN28B
RAP1AENSG00000116473.101297.273701809.71000-0.480305.656904.44400K562MAGOH
RAP1AENSG00000116473.101499.975001806.11110-0.267902.207101.39130K562MATR3
RAP1AENSG00000116473.102105.960701684.269800.322302.808101.89130K562MBNL1
RAP1AENSG00000116473.101766.951901180.547300.581702.901601.99510K562NAA15
RAP1AENSG00000116473.101126.412201366.49180-0.278703.733402.88160K562NSUN2
RAP1AENSG00000116473.10790.627001085.26140-0.457003.371001.73390K562NUSAP1
RAP1AENSG00000116473.102032.064902587.31490-0.348503.330101.75850K562PNPT1
RAP1AENSG00000116473.10583.32440768.07640-0.397003.044902.20350K562POLR2G
RAP1AENSG00000116473.101368.34920981.813600.478803.447002.60860K562PRPF8
RAP1AENSG00000116473.10641.72850988.22630-0.622905.602404.24490K562PSIP1
RAP1AENSG00000116473.102675.163801405.031000.9289016.3678015.08700K562PUS1
RAP1AENSG00000116473.101847.214601368.917900.432205.840005.00570K562RBM15
RAP1AENSG00000116473.101249.870501686.17460-0.432004.203803.14190K562RBM22
RAP1AENSG00000116473.10637.46540901.68590-0.500304.591303.31140K562RCC2
RAP1AENSG00000116473.10519.35730684.25890-0.397802.275701.30150K562SAFB
RAP1AENSG00000116473.101644.410501348.359700.286303.095102.23270K562SF3A3
RAP1AENSG00000116473.10317.55710588.45340-0.889902.954201.64570K562SLBP
RAP1AENSG00000116473.10630.92700854.76820-0.438103.380802.21920K562SRFBP1
RAP1AENSG00000116473.101164.334801723.57950-0.565907.867206.68370K562SRSF1
RAP1AENSG00000116473.10483.86240750.55820-0.633404.248502.90010K562SRSF4
RAP1AENSG00000116473.101286.891301627.65860-0.338902.745801.70220K562SRSF5
RAP1AENSG00000116473.101274.988201744.49010-0.452304.219303.33940K562TARDBP
RAP1AENSG00000116473.101295.903001682.72740-0.376803.899302.90530K562TIA1
RAP1AENSG00000116473.10611.28960950.50140-0.636805.690004.30150K562TIAL1
RAP1AENSG00000116473.10694.030701009.84890-0.541105.113003.73050K562TRIM56
RAP1AENSG00000116473.101031.729701601.54650-0.634407.091104.73670K562TRIP6
RAP1AENSG00000116473.101690.563801385.744600.286702.707101.91220K562U2AF2
RAP1AENSG00000116473.102046.754902476.28110-0.274802.304001.52820K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for RAP1A is not available on ENCORE database.





2 RBPs can affect the splicing of RAP1A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SERAP1AENSG00000116473.10chr1+1122492841122493991122469641122471081122517701122518860.069000.000000.00000includedK562SRSF1
SERAP1AENSG00000116473.10chr1+112170091112170185112162398112162556112233955112234039-0.176000.001820.07061excludedK562HNRNPK
A5SSRAP1AENSG00000116473.10chr1+112233955112234039112233955112233986112237962112238031-0.056000.000730.04380shorterK562SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for RAP1A is not avaliable on ENCORE database.