PLEKHA5

General Information

Gene Name       : PLEKHA5
Gene ID             : ENSG00000052126.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PLEKHA5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PLEKHA5ENSG00000052126.140.320.140.23ENCSR000AEF
HepG2PLEKHA5ENSG00000052126.145.598.967.28ENCSR985KAT
K562PLEKHA5ENSG00000052126.1413.3514.2513.80ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PLEKHA5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PLEKHA5 RNA is bound by 21 proteins.  







eCLIP assay for PLEKHA5 is not avaliable on ENCORE database.





21 proteins are bound to PLEKHA5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr121952887919528917+3'-UTR3.283185.13860K562PUM2
chr121935356019353642+3'-UTR,intron-Distal4.656726.08961HepG2PTBP1
chr121952913719529265+3'-UTR5.9360413.89399K562PUM2
chr121928273219282828+5'-UTR,CDS,intron-Proximal4.296434.69889HepG2GRWD1
chr121928298319283058+5'-UTR,CDS,intron-Proximal3.197464.06531HepG2GRWD1
chr121943661219436685+CDS,intron-Proximal3.259364.44630K562ZNF622
chr121942744419427510+CDS,intron-Proximal4.810055.68196HepG2BCLAF1
chr121942763419427709+CDS4.202324.07072K562UCHL5
chr121942751819427568+CDS4.136093.06595HepG2BCLAF1
chr121951240019512472+CDS4.461593.89826HepG2BCLAF1
chr121948947519489539+CDS4.130113.02457HepG2BCLAF1
chr121951121119511335+CDS3.581603.66187K562ZNF622
chr121951115919511372+CDS,intron-Proximal3.665285.74979HepG2GRWD1
chr121941388619413956+CDS,intron-Distal,intron-Proximal3.145963.55800HepG2BCLAF1
chr121940524719405337+intron-Distal4.245033.50357HepG2QKI
chr121935101319351063+intron-Distal3.635803.97268K562PTBP1
chr121946114719461221+intron-Distal4.450304.78571K562UCHL5
chr121929663419296734+intron-Distal3.517064.72639K562KHSRP
chr121945944519459506+intron-Distal4.347643.75920K562SLTM
chr121928882619288885+intron-Distal3.842677.13618HepG2HNRNPC
chr121946517119465233+intron-Distal3.809023.16028HepG2SUGP2
chr121931001019310097+intron-Distal4.782963.45317HepG2HNRNPL
chr121947302319473161+intron-Distal,intron-Proximal3.823166.69500K562KHSRP
chr121935065619350792+intron-Distal3.953776.48659HepG2SUGP2
chr121946162319461689+intron-Distal4.115394.65731HepG2CSTF2
chr121932908819329189+intron-Distal4.987676.51490HepG2PCBP2
chr121942119919421353+intron-Distal3.953133.89294K562KHSRP
chr121929683319296932+intron-Distal3.156453.20028K562TARDBP
chr121938120219381334+intron-Distal5.103147.27974HepG2QKI
chr121931924719319311+intron-Distal5.3982412.87275K562KHSRP
chr121931992819320059+intron-Distal3.800796.08171HepG2QKI
chr121947316119473289+intron-Distal4.327805.62258K562KHSRP
chr121929701919297159+intron-Distal3.205743.68431K562TARDBP
chr121941891919419007+intron-Distal3.078263.04623HepG2KHSRP
chr121942140919421467+intron-Distal3.998104.49024K562AQR
chr121946162119461689+intron-Distal4.026833.80314K562CSTF2T
chr121944744319447577+intron-Distal4.8859713.23682HepG2QKI
chr121946592019465993+intron-Distal3.242794.08528HepG2SUGP2
chr121947598319476119+intron-Distal4.160603.71997HepG2ILF3
chr121949901019499074+intron-Distal3.289834.56724K562KHSRP
chr121942140119421487+intron-Distal4.456244.27476HepG2AQR
chr121931000919310131+intron-Distal3.219383.40713K562HNRNPL
chr121941895519419066+intron-Distal3.923783.71397K562KHSRP
chr121928316119283226+intron-Distal,intron-Proximal5.326886.68817HepG2EFTUD2
chr121935229119352391+intron-Distal3.698803.41489HepG2CSTF2
chr121929810119298207+intron-Distal4.215654.66266K562TARDBP
chr121944743119447521+intron-Distal5.428086.23225K562QKI
chr121928541219285510+intron-Distal,intron-Proximal3.703744.30679K562KHSRP
chr121935001219350146+intron-Distal4.343295.04209K562MATR3
chr121931790319318035+intron-Distal4.2834415.73891HepG2QKI
chr121928288019282968+intron-Proximal4.389207.08280K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PLEKHA5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PLEKHA5 is not available on ENCORE database.

  • 67 RBPs can affect the levels of PLEKHA5.  








The Knockdown/knockout RNA-Seq assay for PLEKHA5 is not available on ENCORE database.





67 RBPs can affect the gene expression of PLEKHA5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PLEKHA5ENSG00000052126.10518.15810708.62690-0.451601.805701.36580HepG2AKAP1
PLEKHA5ENSG00000052126.10497.75850708.17450-0.508703.927803.22750HepG2BOP1
PLEKHA5ENSG00000052126.10712.56120557.074200.355001.969601.31120HepG2CIRBP
PLEKHA5ENSG00000052126.10399.25150511.58920-0.357702.774002.10760HepG2CKAP4
PLEKHA5ENSG00000052126.10617.60650447.283200.465403.347902.33860HepG2DDX24
PLEKHA5ENSG00000052126.10442.87640678.88310-0.616302.816202.18550HepG2DDX3X
PLEKHA5ENSG00000052126.10317.71850418.58020-0.397802.973802.30180HepG2DNAJC2
PLEKHA5ENSG00000052126.10595.64510431.766200.464103.223902.06690HepG2EIF3G
PLEKHA5ENSG00000052126.10844.58970619.029700.448103.516202.29000HepG2ESF1
PLEKHA5ENSG00000052126.101380.45810984.889600.487006.132405.29770HepG2ETF1
PLEKHA5ENSG00000052126.10503.69790736.97750-0.549103.722602.98950HepG2GPKOW
PLEKHA5ENSG00000052126.10383.03640628.69840-0.714903.581802.87190HepG2MATR3
PLEKHA5ENSG00000052126.10745.54760584.073400.352102.470301.70420HepG2MSI2
PLEKHA5ENSG00000052126.10456.56770624.19940-0.451203.501302.64460HepG2NOL12
PLEKHA5ENSG00000052126.10228.09350502.76650-1.140307.721506.18660HepG2PABPC1
PLEKHA5ENSG00000052126.10768.98920632.583500.281602.902002.29800HepG2PUM1
PLEKHA5ENSG00000052126.10643.61260521.176200.304302.390701.80710HepG2PUS1
PLEKHA5ENSG00000052126.101028.98110634.344800.697805.299104.47560HepG2QKI
PLEKHA5ENSG00000052126.10738.39640494.186700.579202.613901.92820HepG2RAVER1
PLEKHA5ENSG00000052126.10984.64520736.877600.418104.020103.00850HepG2RBM15
PLEKHA5ENSG00000052126.10739.63080575.691500.361402.436501.80010HepG2RBM25
PLEKHA5ENSG00000052126.10799.49860651.816500.294502.119101.63300HepG2NELFE
PLEKHA5ENSG00000052126.10757.78320607.046300.319902.484301.89650HepG2RECQL
PLEKHA5ENSG00000052126.10325.03040419.53970-0.368202.420401.81160HepG2SAFB2
PLEKHA5ENSG00000052126.10775.71620636.484000.285302.037401.61440HepG2SRSF1
PLEKHA5ENSG00000052126.10310.10160461.85880-0.574705.435804.69650HepG2TRIM56
PLEKHA5ENSG00000052126.10798.75200617.273700.371702.462201.86710HepG2U2AF1
PLEKHA5ENSG00000052126.10431.40530616.28280-0.514502.721701.89140HepG2UBE2L3
PLEKHA5ENSG00000052126.10768.79270613.446500.325602.974502.28230HepG2ZC3H8
PLEKHA5ENSG00000052126.10726.60750493.595600.557703.347301.90960HepG2ZRANB2
PLEKHA5ENSG00000052126.10498.289601005.00450-1.0121021.5023020.03170K562AGGF1
PLEKHA5ENSG00000052126.10717.042901104.30370-0.623007.160805.39720K562AKAP8
PLEKHA5ENSG00000052126.10616.356801045.74180-0.762707.355106.24550K562AKAP8L
PLEKHA5ENSG00000052126.10504.15160984.83120-0.9660013.5238012.36610K562AQR
PLEKHA5ENSG00000052126.10782.705601097.21430-0.487306.060504.64230K562ATP5C1
PLEKHA5ENSG00000052126.10597.66620796.86510-0.415002.746401.87650K562BOP1
PLEKHA5ENSG00000052126.10389.12130510.06540-0.390502.996101.61380K562DDX27
PLEKHA5ENSG00000052126.101005.407501183.74630-0.235602.163301.57550K562DDX47
PLEKHA5ENSG00000052126.10350.76350461.58690-0.396102.713101.42420K562DDX6
PLEKHA5ENSG00000052126.10820.641001125.36160-0.455605.726704.41010K562DKC1
PLEKHA5ENSG00000052126.10322.13970480.43670-0.576703.640602.58140K562EFTUD2
PLEKHA5ENSG00000052126.10925.97930762.478400.280202.379101.70370K562EIF2S2
PLEKHA5ENSG00000052126.10361.00900514.45560-0.511002.667301.65150K562EIF3D
PLEKHA5ENSG00000052126.10451.58660584.52440-0.372302.666301.88260K562EIF3G
PLEKHA5ENSG00000052126.10303.72770415.18430-0.451002.865001.54780K562EWSR1
PLEKHA5ENSG00000052126.10582.90260902.38530-0.630506.464005.12800K562FIP1L1
PLEKHA5ENSG00000052126.10482.19440651.08100-0.433203.216601.64710K562G3BP1
PLEKHA5ENSG00000052126.10669.25370482.238300.472702.556901.88200K562G3BP2
PLEKHA5ENSG00000052126.10565.32800808.95960-0.517004.490503.48340K562GPKOW
PLEKHA5ENSG00000052126.10542.745501016.17190-0.9048011.8486010.25870K562GRSF1
PLEKHA5ENSG00000052126.10467.25330681.00310-0.543503.451902.26010K562IGF2BP2
PLEKHA5ENSG00000052126.10519.42640692.67320-0.415303.077201.80460K562IGF2BP3
PLEKHA5ENSG00000052126.10776.066801109.83170-0.516105.243004.03280K562KIF1C
PLEKHA5ENSG00000052126.10700.512201062.35100-0.600806.190904.33290K562MAK16
PLEKHA5ENSG00000052126.10478.28810714.25770-0.578605.687404.30070K562MATR3
PLEKHA5ENSG00000052126.10867.212801243.28650-0.519705.868404.45430K562MBNL1
PLEKHA5ENSG00000052126.10605.49250789.63480-0.383102.730401.86020K562METAP2
PLEKHA5ENSG00000052126.10667.55130847.33450-0.344103.184402.31670K562MTPAP
PLEKHA5ENSG00000052126.10622.46140871.45040-0.485402.781601.89560K562NAA15
PLEKHA5ENSG00000052126.10442.91430805.90350-0.863604.339803.02580K562PABPN1
PLEKHA5ENSG00000052126.10618.363001024.33910-0.728208.502606.86910K562PPIG
PLEKHA5ENSG00000052126.10295.30300467.51890-0.662804.348203.40890K562PRPF8
PLEKHA5ENSG00000052126.10379.23790577.14950-0.605804.411303.22940K562PSIP1
PLEKHA5ENSG00000052126.10758.444501037.16710-0.451503.558802.95450K562PUS1
PLEKHA5ENSG00000052126.10553.698701010.49830-0.8679014.7690013.38440K562RBM15
PLEKHA5ENSG00000052126.10368.95390526.48370-0.512903.791002.62690K562RCC2
PLEKHA5ENSG00000052126.10449.50110737.02570-0.713402.524901.39690K562SF1
PLEKHA5ENSG00000052126.10452.62630643.79570-0.508303.900502.61630K562SRSF5
PLEKHA5ENSG00000052126.10715.43290554.305300.368002.618601.82270K562SYNCRIP
PLEKHA5ENSG00000052126.10543.77040689.90590-0.343402.016601.40640K562TARDBP
PLEKHA5ENSG00000052126.10510.13400665.49210-0.383502.721201.91150K562TIA1
PLEKHA5ENSG00000052126.10403.78880555.13230-0.459202.582001.68160K562TIAL1
PLEKHA5ENSG00000052126.10402.84630589.65530-0.549603.972802.79610K562TRIM56
PLEKHA5ENSG00000052126.10682.746401051.50030-0.623002.975201.61790K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PLEKHA5 is not available on ENCORE database.





4 RBPs can affect the splicing of PLEKHA5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPLEKHA5ENSG00000052126.10chr12+194404061944049019436213194366791947349519473558-0.424000.000330.00811excludedHepG2U2AF1
SEPLEKHA5ENSG00000052126.10chr12+194987751949882219496256194963681950133219501453-0.272000.000580.00773excludedK562AQR
SEPLEKHA5ENSG00000052126.10chr12+194404061944049019436213194366791947349519473558-0.449000.000140.00385excludedK562U2AF2
MXEPLEKHA5ENSG00000052126.10chr12+1941036619410471194138821941395519407978194080991941868319418784-0.281000.003000.091542includedK562FXR1
MXEPLEKHA5ENSG00000052126.10chr12+1941036619410471194138821941395519407978194080991941868319418784-0.216000.015650.077152includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PLEKHA5 is not avaliable on ENCORE database.