PFDN1

General Information

Gene Name       : PFDN1
Gene ID             : ENSG00000113068.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PFDN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PFDN1ENSG00000113068.9120.04102.16111.10ENCSR000AEF
HepG2PFDN1ENSG00000113068.990.38102.3796.38ENCSR985KAT
K562PFDN1ENSG00000113068.971.7580.0075.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PFDN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PFDN1 RNA is bound by 18 proteins.  







eCLIP assay for PFDN1 is not avaliable on ENCORE database.





18 proteins are bound to PFDN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5139625120139625224-3'-UTR,CDS,intron-Distal,intron-Proximal3.9464921.38189K562UPF1
chr5139625044139625093-3'-UTR,CDS,intron-Distal,intron-Proximal3.560014.27354HepG2UPF1
chr5139625304139625387-3'-UTR,intron-Distal3.8576513.24894K562YBX3
chr5139625010139625120-3'-UTR,CDS,intron-Distal,intron-Proximal3.7603127.78183K562UPF1
chr5139625306139625386-3'-UTR,intron-Distal3.382493.76556HepG2STAU2
chr5139625291139625390-3'-UTR,intron-Distal4.060796.35488HepG2AKAP1
chr5139625296139625392-3'-UTR,intron-Distal4.240403.81597K562RBM15
chr5139625286139625329-3'-UTR,intron-Distal3.635513.04123K562LIN28B
chr5139625224139625258-3'-UTR,intron-Distal3.693245.95678K562UPF1
chr5139625145139625203-3'-UTR,intron-Distal4.386334.66439HepG2AKAP1
chr5139625455139625527-3'-UTR,intron-Distal4.852497.10674HepG2UPF1
chr5139624687139624748-3'-UTR,intron-Distal,intron-Proximal5.108796.34419K562PUM2
chr5139625317139625384-3'-UTR,intron-Distal5.2853410.25977HepG2UPF1
chr5139625535139625609-3'-UTR,CDS,intron-Distal3.956933.45275HepG2LARP4
chr5139625121139625237-3'-UTR,CDS,intron-Distal,intron-Proximal6.2928121.87194HepG2UPF1
chr5139625032139625103-3'-UTR,CDS,intron-Distal,intron-Proximal4.068176.16190HepG2AKAP1
chr5139625117139625219-3'-UTR,CDS,intron-Distal,intron-Proximal3.401736.16583HepG2STAU2
chr5139680139139680168-CDS,intron-Distal,intron-Proximal3.513634.46401K562DDX3X
chr5139646710139646739-intron-Distal8.74708101.91068HepG2RBFOX2
chr5139646324139646384-intron-Distal6.5082120.68713HepG2QKI
chr5139646711139646743-intron-Distal7.5588027.05885HepG2QKI
chr5139646394139646491-intron-Distal7.53057113.30239HepG2DROSHA
chr5139646525139646546-intron-Distal7.1510149.77736HepG2QKI
chr5139646591139646621-intron-Distal5.7063246.03392HepG2DROSHA
chr5139655807139655888-intron-Distal3.781065.06177HepG2SUGP2
chr5139646242139646285-intron-Distal6.5296628.79068HepG2DROSHA
chr5139646469139646583-intron-Distal6.9877238.06555K562DROSHA
chr5139646666139646692-intron-Distal6.7317942.22529HepG2DDX6
chr5139647052139647083-intron-Distal4.8810212.65364HepG2RBFOX2
chr5139646686139646710-intron-Distal8.03822121.07736HepG2RBFOX2
chr5139646739139646767-intron-Distal7.8114249.93509HepG2RBFOX2
chr5139646592139646619-intron-Distal5.7479118.92603HepG2QKI
chr5139680214139680303-intron-Distal,intron-Proximal3.667993.24603K562KHSRP
chr5139653477139653541-intron-Distal4.120876.32636HepG2U2AF2
chr5139646546139646572-intron-Distal6.6472538.58339HepG2QKI
chr5139646553139646574-intron-Distal7.1572472.91318HepG2DROSHA
chr5139646545139646621-intron-Distal8.2953448.57826HepG2DDX6
chr5139646428139646475-intron-Distal6.7842130.54223HepG2QKI
chr5139646583139646622-intron-Distal5.9649218.56001K562DROSHA
chr5139644550139644621-intron-Distal4.163295.57156HepG2QKI
chr5139646616139646670-intron-Distal7.21723140.92134HepG2RBFOX2
chr5139646744139646791-intron-Distal6.9881635.56989HepG2DROSHA
chr5139646572139646592-intron-Distal5.8729422.11754HepG2QKI
chr5139646622139646689-intron-Distal7.59713148.37924HepG2DROSHA
chr5139646644139646666-intron-Distal6.9857538.82604HepG2DDX6
chr5139646491139646521-intron-Distal8.46912100.48203HepG2DROSHA
chr5139646743139646785-intron-Distal6.8513821.21085HepG2QKI
chr5139646791139646850-intron-Distal5.7115730.57645HepG2DROSHA
chr5139646574139646591-intron-Distal5.7792952.77902HepG2DROSHA
chr5139646499139646545-intron-Distal8.2401547.98356HepG2DDX6
chr5139646475139646525-intron-Distal8.0544947.26950HepG2QKI
chr5139646693139646746-intron-Distal6.5336727.72641K562DROSHA
chr5139646670139646686-intron-Distal7.87267106.52971HepG2RBFOX2
chr5139646433139646486-intron-Distal5.177696.81444K562RBFOX2
chr5139646568139646616-intron-Distal7.5199535.98610HepG2RBFOX2
chr5139655853139655944-intron-Distal3.696983.10961HepG2MATR3
chr5139646514139646551-intron-Distal7.78278100.02992HepG2RBFOX2
chr5139646689139646744-intron-Distal8.4175386.26927HepG2DROSHA
chr5139646625139646777-intron-Distal7.0026427.16842K562RBFOX2
chr5139646493139646615-intron-Distal6.5918110.13101K562DDX6
chr5139646579139646625-intron-Distal5.8626511.74926K562RBFOX2
chr5139646692139646784-intron-Distal7.6351661.84214HepG2DDX6
chr5139646521139646546-intron-Distal7.79827115.15175HepG2DROSHA
chr5139646871139646901-intron-Distal6.2534514.83926HepG2RBFOX2
chr5139646459139646471-intron-Distal4.993138.19881HepG2DDX6
chr5139646479139646514-intron-Distal7.7573841.85175HepG2RBFOX2
chr5139646551139646568-intron-Distal7.0913566.54705HepG2RBFOX2
chr5139646486139646579-intron-Distal6.5260919.00972K562RBFOX2
chr5139648609139648672-intron-Distal4.315503.18269HepG2XPO5
chr5139646633139646711-intron-Distal8.3234445.08671HepG2QKI
chr5139646615139646774-intron-Distal7.3272918.53891K562DDX6
chr5139646622139646693-intron-Distal8.4441256.08134K562DROSHA
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PFDN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PFDN1 is not available on ENCORE database.

  • 63 RBPs can affect the levels of PFDN1.  








The Knockdown/knockout RNA-Seq assay for PFDN1 is not available on ENCORE database.





63 RBPs can affect the gene expression of PFDN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PFDN1ENSG00000113068.51783.396501041.328700.7761022.5810021.22110HepG2ACO1
PFDN1ENSG00000113068.5763.49300973.44530-0.350502.311201.39850HepG2ADAR
PFDN1ENSG00000113068.52293.702501593.746000.525204.403603.75350HepG2AKAP1
PFDN1ENSG00000113068.5936.012801318.72070-0.494504.066503.12240HepG2ASCC1
PFDN1ENSG00000113068.51004.982201659.95540-0.7240017.1011015.65960HepG2AUH
PFDN1ENSG00000113068.5689.32280981.50310-0.509805.095403.45130HepG2BUD13
PFDN1ENSG00000113068.51666.06360864.759400.946008.099406.80380HepG2CNOT7
PFDN1ENSG00000113068.5792.39510998.26550-0.333203.085802.00990HepG2YBX3
PFDN1ENSG00000113068.51820.339301429.563200.348504.331203.55990HepG2CELF1
PFDN1ENSG00000113068.51362.082501537.30930-0.174601.945401.30790HepG2DAZAP1
PFDN1ENSG00000113068.5787.05130963.09530-0.291203.095602.21730HepG2DDX19B
PFDN1ENSG00000113068.51196.005201526.75180-0.352202.326301.74770HepG2DDX3X
PFDN1ENSG00000113068.51314.13600904.167100.539404.121503.19780HepG2DDX55
PFDN1ENSG00000113068.5645.73220945.40690-0.550005.386804.04840HepG2DHX30
PFDN1ENSG00000113068.5812.77540996.27810-0.293702.723302.05070HepG2DKC1
PFDN1ENSG00000113068.5983.966701260.79240-0.357602.333001.78570HepG2EIF2S1
PFDN1ENSG00000113068.51273.699101516.49670-0.251702.758601.92280HepG2EIF4G1
PFDN1ENSG00000113068.51360.246901017.594100.418604.159003.13490HepG2EWSR1
PFDN1ENSG00000113068.51331.64150921.629800.530806.048504.46550HepG2FASTKD2
PFDN1ENSG00000113068.51058.77670789.741100.422802.741602.10290HepG2GPKOW
PFDN1ENSG00000113068.5755.70440989.58650-0.389002.987702.31930HepG2HNRNPA1
PFDN1ENSG00000113068.51700.129801412.745500.267002.802301.86380HepG2HNRNPA2B1
PFDN1ENSG00000113068.51261.250601478.40220-0.229202.063001.43760HepG2HNRNPF
PFDN1ENSG00000113068.5952.608401320.22180-0.470804.148303.30760HepG2HNRNPK
PFDN1ENSG00000113068.5654.17830912.69040-0.480404.725403.52060HepG2HNRNPM
PFDN1ENSG00000113068.51015.489101455.81240-0.519606.607005.53060HepG2IGF2BP1
PFDN1ENSG00000113068.5621.178201325.59990-1.0936016.5756015.08920HepG2IGF2BP2
PFDN1ENSG00000113068.51386.278001116.937500.311604.408703.50230HepG2ILF2
PFDN1ENSG00000113068.51768.267401414.055300.322401.947601.41350HepG2MATR3
PFDN1ENSG00000113068.5749.470201070.53300-0.514405.496204.39010HepG2MSI2
PFDN1ENSG00000113068.51027.268501447.39300-0.494603.889003.14260HepG2NCBP2
PFDN1ENSG00000113068.51201.530301524.38320-0.343403.868102.96620HepG2NOL12
PFDN1ENSG00000113068.51027.247501289.13030-0.327602.009601.38600HepG2PABPC4
PFDN1ENSG00000113068.5804.199201020.18510-0.343203.547402.68080HepG2PRPF4
PFDN1ENSG00000113068.51130.273201543.51100-0.449505.692304.74240HepG2PUM2
PFDN1ENSG00000113068.51860.285901357.017200.455005.876404.68470HepG2RBM15
PFDN1ENSG00000113068.5777.158701592.97740-1.0354027.2609025.96780HepG2RBM22
PFDN1ENSG00000113068.51213.671901552.95630-0.355604.311403.66310HepG2NELFE
PFDN1ENSG00000113068.51026.752701446.46650-0.494407.740606.78640HepG2RECQL
PFDN1ENSG00000113068.5690.778701048.39560-0.601905.478604.37460HepG2RPS2
PFDN1ENSG00000113068.52054.906601128.243800.864904.971304.05030HepG2SF3A3
PFDN1ENSG00000113068.51672.271301452.734400.202902.039101.51950HepG2SF3B4
PFDN1ENSG00000113068.52035.707601799.186600.178101.940601.49860HepG2SRFBP1
PFDN1ENSG00000113068.51934.312801516.388200.351105.399704.79450HepG2SRSF1
PFDN1ENSG00000113068.51191.876901452.45290-0.285303.119102.38630HepG2SRSF7
PFDN1ENSG00000113068.51502.51430900.087600.739107.562906.53470HepG2SUPV3L1
PFDN1ENSG00000113068.5959.414101363.12180-0.506706.883006.06800HepG2TAF15
PFDN1ENSG00000113068.5886.086601062.45910-0.261901.924201.49070HepG2TIAL1
PFDN1ENSG00000113068.51353.81110966.018700.486807.846506.92040HepG2UTP3
PFDN1ENSG00000113068.51266.252101006.800400.330704.301103.49270HepG2ZC3H8
PFDN1ENSG00000113068.51408.827101100.445300.356305.647904.93810HepG2ZNF622
PFDN1ENSG00000113068.51550.743201131.969100.454007.211406.35830K562AGGF1
PFDN1ENSG00000113068.52234.742001503.217500.572006.986906.12390K562AQR
PFDN1ENSG00000113068.5917.60990738.276500.313602.139001.41280K562EIF4A3
PFDN1ENSG00000113068.5548.23110820.58150-0.581904.997003.84080K562FMR1
PFDN1ENSG00000113068.51008.88610767.778900.393904.232103.50660K562FXR1
PFDN1ENSG00000113068.51202.49380920.409300.385603.524402.57010K562MAGOH
PFDN1ENSG00000113068.51163.46960737.193200.658202.793001.79790K562PABPN1
PFDN1ENSG00000113068.51207.38070764.764000.658706.856105.67470K562PRPF8
PFDN1ENSG00000113068.51108.01410894.235800.309102.482401.84800K562PTBP1
PFDN1ENSG00000113068.51687.326801168.138300.530405.671904.92760K562PUS1
PFDN1ENSG00000113068.51396.444601138.156300.295002.788702.19350K562RBM15
PFDN1ENSG00000113068.51257.65360876.650100.520605.934404.90770K562SRSF1
PFDN1ENSG00000113068.5586.03600765.87440-0.386102.705401.67230K562SRSF4
PFDN1ENSG00000113068.5804.736701012.86080-0.331802.860301.31090K562SRSF9
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PFDN1 is not available on ENCORE database.





12 RBPs can affect the splicing of PFDN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.158000.000000.00000excludedK562PRPF8
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.097000.000010.00108excludedHepG2RBM22
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.139000.000000.00020excludedHepG2PRPF8
SEPFDN1ENSG00000113068.5chr5-139661033139661118139624623139625642139680000139680167-0.055000.000000.00000excludedHepG2U2AF2
SEPFDN1ENSG00000113068.5chr5-139680000139680167139660544139661118139682625139682671-0.224000.000000.00000excludedK562AQR
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.189000.000000.00000excludedHepG2SRSF7
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.084000.000000.00000excludedK562PUS1
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.089000.000100.03233excludedHepG2EFTUD2
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.071000.000480.06858excludedHepG2HNRNPA1
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.117000.000000.00025excludedK562EFTUD2
SEPFDN1ENSG00000113068.5chr5-1396800001396801671396610331396611181396826251396827060.056000.000000.00091includedHepG2HNRNPL
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.056000.000200.03454excludedHepG2HNRNPUL1
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.052000.000120.08658excludedK562TRA2A
SEPFDN1ENSG00000113068.5chr5-139680000139680167139661033139661118139682625139682706-0.064000.000010.00073excludedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PFDN1 is not avaliable on ENCORE database.