NSMCE4A

General Information

Gene Name       : NSMCE4A
Gene ID             : ENSG00000107672.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: NSMCE4A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NSMCE4AENSG00000107672.1458.2150.1954.20ENCSR000AEF
HepG2NSMCE4AENSG00000107672.1446.9776.0261.49ENCSR985KAT
K562NSMCE4AENSG00000107672.1433.8032.7033.25ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NSMCE4A is not avaliable on ENCORE database.



Proteins bound to RNA
  • NSMCE4A RNA is bound by 10 proteins.  







eCLIP assay for NSMCE4A is not avaliable on ENCORE database.





10 proteins are bound to NSMCE4A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10123718849123718894-3'-UTR,CDS,intron-Distal,intron-Proximal4.618724.01763HepG2GRWD1
chr10123716669123716763-3'-UTR,intron-Distal5.9627011.85849K562PUM2
chr10123718841123718916-3'-UTR,CDS,intron-Distal,intron-Proximal3.4517010.64832HepG2PPIG
chr10123733528123733591-5'-UTR,CDS,intron-Distal4.290837.79455HepG2PPIG
chr10123734637123734692-5'-UTR,CDS,intron-Distal,intron-Proximal4.308864.72880HepG2GRWD1
chr10123730465123730574-5'-UTR,CDS,intron-Distal,intron-Proximal3.093537.61685HepG2PPIG
chr10123720944123721014-CDS,intron-Distal4.3485611.87770HepG2BCLAF1
chr10123718894123718925-CDS,intron-Distal,intron-Proximal4.694723.56019HepG2GRWD1
chr10123722749123722768-CDS,intron-Distal,intron-Proximal4.458618.98365HepG2PPIG
chr10123734435123734562-CDS,intron-Distal4.022266.14128HepG2SRSF1
chr10123722748123722807-CDS,intron-Distal,intron-Proximal3.880803.84295K562GRWD1
chr10123724799123724843-CDS,intron-Distal,intron-Proximal3.885566.84754HepG2GRWD1
chr10123719015123719063-CDS,intron-Distal,intron-Proximal3.710353.60157HepG2GRWD1
chr10123727196123727258-CDS,intron-Distal,intron-Proximal3.503987.02567HepG2BCLAF1
chr10123719013123719056-CDS,intron-Distal,intron-Proximal4.647929.30195HepG2BCLAF1
chr10123721010123721032-CDS,intron-Distal3.912706.08299HepG2PPIG
chr10123722825123722843-CDS,intron-Distal3.678044.65365HepG2GRWD1
chr10123734441123734494-CDS,intron-Distal3.075006.47139HepG2PPIG
chr10123734335123734395-CDS,intron-Distal,intron-Proximal4.161035.64484HepG2PRPF8
chr10123720952123721011-CDS,intron-Distal3.067323.99689HepG2GRWD1
chr10123722765123722845-CDS,intron-Distal,intron-Proximal4.048045.80935K562ZNF622
chr10123722749123722788-CDS,intron-Distal,intron-Proximal4.7728111.47391HepG2BCLAF1
chr10123727192123727258-CDS,intron-Distal,intron-Proximal3.118724.79429HepG2GRWD1
chr10123722788123722845-CDS,intron-Distal,intron-Proximal4.130119.39582HepG2BCLAF1
chr10123734640123734674-CDS,intron-Distal,intron-Proximal4.127123.79199HepG2PPIG
chr10123724843123724881-CDS,intron-Distal,intron-Proximal4.276474.23295HepG2GRWD1
chr10123720960123721036-CDS,intron-Distal,intron-Proximal3.164683.39477K562BUD13
chr10123734510123734587-CDS,intron-Distal3.997343.15006K562RBM15
chr10123718887123718926-CDS,intron-Distal,intron-Proximal3.890727.89209HepG2BCLAF1
chr10123722741123722781-CDS,intron-Distal,intron-Proximal3.108053.84692K562UCHL5
chr10123721014123721032-CDS,intron-Distal3.619346.39464HepG2BCLAF1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NSMCE4A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NSMCE4A is not available on ENCORE database.

  • 76 RBPs can affect the levels of NSMCE4A.  








The Knockdown/knockout RNA-Seq assay for NSMCE4A is not available on ENCORE database.





76 RBPs can affect the gene expression of NSMCE4A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NSMCE4AENSG00000107672.10530.73180755.67150-0.509806.343105.50000HepG2ACO1
NSMCE4AENSG00000107672.10592.45350759.12720-0.357603.278802.45260HepG2AKAP8L
NSMCE4AENSG00000107672.10597.02030801.42830-0.424802.720601.94210HepG2ASCC1
NSMCE4AENSG00000107672.10365.73800577.01600-0.657804.853703.69240HepG2BCLAF1
NSMCE4AENSG00000107672.10434.80710694.55600-0.675706.245705.38810HepG2BOP1
NSMCE4AENSG00000107672.10549.74570774.95900-0.495404.633403.66610HepG2CALR
NSMCE4AENSG00000107672.10735.970701000.88480-0.443602.526201.59920HepG2CCAR1
NSMCE4AENSG00000107672.10561.42520761.41260-0.439602.854702.06940HepG2CIRBP
NSMCE4AENSG00000107672.10508.82370755.39350-0.570107.969506.95270HepG2CKAP4
NSMCE4AENSG00000107672.10334.41080637.63890-0.931109.515108.31350HepG2CPSF6
NSMCE4AENSG00000107672.10828.796901054.77990-0.347902.959302.29850HepG2CELF1
NSMCE4AENSG00000107672.10482.05930651.45520-0.434502.266301.64410HepG2DDX21
NSMCE4AENSG00000107672.10668.28660927.83580-0.473403.306902.63100HepG2DDX3X
NSMCE4AENSG00000107672.10488.09410652.95290-0.419802.305001.59320HepG2DDX55
NSMCE4AENSG00000107672.10495.98810724.08630-0.545902.399901.48910HepG2DDX59
NSMCE4AENSG00000107672.10630.28960803.25320-0.349802.222801.31420HepG2DDX5
NSMCE4AENSG00000107672.10513.03220797.03900-0.635604.635203.85330HepG2DDX6
NSMCE4AENSG00000107672.10489.76200766.20410-0.645605.161704.36610HepG2EIF2S1
NSMCE4AENSG00000107672.10634.16350846.74140-0.417102.377601.78390HepG2EIF4A3
NSMCE4AENSG00000107672.10505.88440824.42970-0.704604.714503.83080HepG2EIF4B
NSMCE4AENSG00000107672.10847.109101071.91740-0.339602.618101.82460HepG2EIF4G2
NSMCE4AENSG00000107672.10794.682901279.62120-0.6873012.8860011.74630HepG2ETF1
NSMCE4AENSG00000107672.10347.38080638.73460-0.878703.547302.39150HepG2FTO
NSMCE4AENSG00000107672.10619.43600792.51830-0.355501.945801.38340HepG2G3BP1
NSMCE4AENSG00000107672.10456.69460731.95370-0.680505.590404.13260HepG2GNB2L1
NSMCE4AENSG00000107672.10342.40860722.80970-1.0779011.5634010.33030HepG2GPKOW
NSMCE4AENSG00000107672.10395.13240627.02500-0.666205.653304.69010HepG2HNRNPC
NSMCE4AENSG00000107672.10619.44200760.56950-0.296102.673301.96700HepG2HNRNPF
NSMCE4AENSG00000107672.10377.26430689.79090-0.870608.611307.56600HepG2HNRNPLL
NSMCE4AENSG00000107672.10590.03830805.57510-0.449203.003302.30430HepG2IGF2BP2
NSMCE4AENSG00000107672.10356.25840647.87070-0.862809.132506.33990HepG2CCAR2
NSMCE4AENSG00000107672.10556.69960690.70770-0.311202.791401.77160HepG2KIF1C
NSMCE4AENSG00000107672.10811.342501056.86060-0.381402.029701.32700HepG2LARP4
NSMCE4AENSG00000107672.10613.76970879.66140-0.519303.664002.93930HepG2NCBP2
NSMCE4AENSG00000107672.10452.27420611.63430-0.435502.590001.86550HepG2NSUN2
NSMCE4AENSG00000107672.10518.59400783.38800-0.595104.618803.69740HepG2PABPC4
NSMCE4AENSG00000107672.10524.46800741.83010-0.500205.591504.77560HepG2PCBP1
NSMCE4AENSG00000107672.10353.86430503.62650-0.509202.994202.15610HepG2PRPF8
NSMCE4AENSG00000107672.10734.770201073.71990-0.547304.443203.70850HepG2PUF60
NSMCE4AENSG00000107672.10828.151201138.93410-0.459704.640703.78310HepG2PUM2
NSMCE4AENSG00000107672.10813.149501005.91230-0.306902.362201.56320HepG2RBM15
NSMCE4AENSG00000107672.10843.369701069.53630-0.342703.225602.67750HepG2RBM22
NSMCE4AENSG00000107672.10514.55520819.44350-0.671307.173106.14880HepG2RPLP0
NSMCE4AENSG00000107672.10318.93360508.25860-0.672305.655004.81150HepG2RPS19
NSMCE4AENSG00000107672.10633.98990851.23240-0.425101.987301.41390HepG2SF3A3
NSMCE4AENSG00000107672.10442.42070682.75470-0.625905.224604.27660HepG2SF3B1
NSMCE4AENSG00000107672.10539.08640785.87940-0.543806.304105.47280HepG2SF3B4
NSMCE4AENSG00000107672.10784.010101029.34280-0.392803.490202.71700HepG2SLBP
NSMCE4AENSG00000107672.10428.97200853.30350-0.992203.343201.86970HepG2SNRNP200
NSMCE4AENSG00000107672.10438.28760759.68500-0.793505.084704.01410HepG2SNRNP70
NSMCE4AENSG00000107672.10765.349601060.03270-0.469904.843904.05320HepG2SRSF5
NSMCE4AENSG00000107672.10519.25230747.26300-0.525206.706705.70100HepG2SRSF7
NSMCE4AENSG00000107672.10451.19630667.35820-0.564706.822206.02420HepG2SRSF9
NSMCE4AENSG00000107672.10795.317101048.87680-0.399204.824804.18420HepG2SSB
NSMCE4AENSG00000107672.10986.705601205.64280-0.289102.493601.89730HepG2SUCLG1
NSMCE4AENSG00000107672.10392.24080563.06220-0.521604.245603.09240HepG2SUPT6H
NSMCE4AENSG00000107672.10334.88280649.98310-0.956708.741907.65020HepG2SUPV3L1
NSMCE4AENSG00000107672.10295.02470672.34230-1.1884015.3255013.84790HepG2TARDBP
NSMCE4AENSG00000107672.10476.50380605.27270-0.345101.767901.34950HepG2TIAL1
NSMCE4AENSG00000107672.10398.15890610.65300-0.617007.478406.62800HepG2TRIM56
NSMCE4AENSG00000107672.10749.323501048.82990-0.485104.277603.16240HepG2TUFM
NSMCE4AENSG00000107672.10522.97960713.41500-0.448003.380802.69190HepG2U2AF1
NSMCE4AENSG00000107672.10386.49910993.52910-1.362105.081503.71760HepG2U2AF2
NSMCE4AENSG00000107672.10828.936701110.07210-0.421302.625301.80930HepG2UBE2L3
NSMCE4AENSG00000107672.10636.68660754.91070-0.245701.906001.30820HepG2UPF1
NSMCE4AENSG00000107672.10569.61230830.26050-0.543608.133107.32380HepG2ZNF622
NSMCE4AENSG00000107672.10379.56440504.63540-0.410902.079901.57490K562AGGF1
NSMCE4AENSG00000107672.10399.93670525.07670-0.392802.174401.59290K562AKAP8L
NSMCE4AENSG00000107672.10438.93440780.98220-0.831308.810807.86000K562AQR
NSMCE4AENSG00000107672.10263.51350398.28110-0.595902.132701.37300K562BOP1
NSMCE4AENSG00000107672.10262.95490423.52250-0.687602.837202.04470K562CPSF6
NSMCE4AENSG00000107672.10459.89070565.00630-0.297001.974401.34860K562EIF2S2
NSMCE4AENSG00000107672.10482.09890328.320500.554104.610803.85690K562FXR1
NSMCE4AENSG00000107672.10504.17040336.221800.584403.262102.48320K562G3BP2
NSMCE4AENSG00000107672.10193.73040404.38800-1.061705.122004.04730K562GPKOW
NSMCE4AENSG00000107672.10206.44950359.59400-0.800605.744204.91470K562HNRNPC
NSMCE4AENSG00000107672.10408.26390555.03870-0.443103.519202.51270K562HNRNPU
NSMCE4AENSG00000107672.10783.289401108.33510-0.500805.105102.54400K562CCAR2
NSMCE4AENSG00000107672.10228.61550345.22270-0.594602.365701.51150K562KRR1
NSMCE4AENSG00000107672.10290.21850469.80440-0.694902.479901.55620K562PABPN1
NSMCE4AENSG00000107672.10395.20210520.86980-0.398302.273601.77190K562PUS1
NSMCE4AENSG00000107672.10372.80820517.82890-0.474003.753402.81120K562SF3A3
NSMCE4AENSG00000107672.10261.19150384.48420-0.557802.249401.38310K562SF3B1
NSMCE4AENSG00000107672.10201.75430349.67860-0.793406.627505.26800K562SF3B4
NSMCE4AENSG00000107672.10291.97030493.37260-0.756902.698201.48810K562SNRNP200
NSMCE4AENSG00000107672.10247.31760421.97380-0.770803.996903.13910K562TARDBP
NSMCE4AENSG00000107672.10383.77820556.38560-0.535805.299404.33990K562UPF1
NSMCE4AENSG00000107672.10674.39920879.86770-0.383702.973902.07440K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NSMCE4A is not available on ENCORE database.





6 RBPs can affect the splicing of NSMCE4A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENSMCE4AENSG00000107672.10chr10-1237196651237197331237190151237191101237198721237199210.093000.000000.00007includedHepG2U2AF1
SENSMCE4AENSG00000107672.10chr10-123719015123719110123718838123718925123719872123719921-0.111000.003660.03600excludedK562AQR
SENSMCE4AENSG00000107672.10chr10-1237196651237197331237190151237191101237198721237199210.079000.000170.01670includedHepG2FTO
SENSMCE4AENSG00000107672.10chr10-123719015123719110123718838123718925123719872123719921-0.359000.000000.00003excludedK562U2AF2
SENSMCE4AENSG00000107672.10chr10-1237330371237331141237304531237305841237335181237335960.146000.000000.00039includedK562TARDBP
SENSMCE4AENSG00000107672.10chr10-123719015123719110123718838123718925123719872123719921-0.145000.001780.05848excludedK562TARDBP
SENSMCE4AENSG00000107672.10chr10-1237213551237216221237209371237210321237227521237228430.172000.000000.00000includedHepG2HNRNPC
SENSMCE4AENSG00000107672.10chr10-123719015123719110123718838123718925123719872123719921-0.291000.000050.00140excludedK562HNRNPC
MXENSMCE4AENSG00000107672.10chr10-1237209371237210321237248001237249001237198721237199211237271691237273210.143000.001370.011961includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NSMCE4A is not avaliable on ENCORE database.