MKRN2

General Information

Gene Name       : MKRN2
Gene ID             : ENSG00000075975.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MKRN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MKRN2ENSG00000075975.1519.9721.7620.87ENCSR000AEF
HepG2MKRN2ENSG00000075975.1522.1621.8522.01ENCSR985KAT
K562MKRN2ENSG00000075975.1531.8330.4931.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
MKRN2HepG2CRISPRBGHcLV24-41,BGHcLV24-42BGHcLV24-1,BGHcLV24-2NotSatisfiedENCODE4
MKRN2HepG2CRISPRBGHcLV24-43,BGHcLV24-44BGHcLV24-1,BGHcLV24-2NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MKRN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MKRN2 RNA is bound by 13 proteins.  







eCLIP assay for MKRN2 is not avaliable on ENCORE database.





13 proteins are bound to MKRN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr31262474112624788+3'-UTR3.828773.15048K562NOLC1
chr31262431512624392+3'-UTR3.919437.48557K562IGF2BP1
chr31262449212624528+3'-UTR3.518156.04024K562UPF1
chr31262487412624919+3'-UTR4.136677.12652K562UPF1
chr31262379712623802+3'-UTR3.126253.78791K562RBM15
chr31262384712623902+3'-UTR4.570718.11444HepG2SUB1
chr31262439712624532+3'-UTR3.150293.47114HepG2UPF1
chr31262384112623917+3'-UTR5.535848.34710K562AQR
chr31259863312598758+5'-UTR,CDS,intron-Proximal5.6707116.83003HepG2PRPF8
chr31259866712598693+CDS,intron-Proximal3.392405.66421K562PRPF8
chr31261037312610485+CDS,intron-Distal,intron-Proximal3.310225.21590K562DDX3X
chr31261174512611766+CDS,intron-Proximal3.475904.41130K562AQR
chr31261173912611856+CDS,intron-Distal,intron-Proximal3.515956.43995K562PRPF8
chr31262325312623308+CDS,intron-Proximal3.532206.71722K562SF3B4
chr31261037712610416+CDS,intron-Distal3.739749.05969K562YBX3
chr31261355512613606+CDS,intron-Proximal4.924375.55733K562BUD13
chr31262330412623368+CDS,intron-Proximal4.0812213.62242K562PUM2
chr31261166412611741+CDS3.496916.76685K562YBX3
chr31259973212599781+intron-Distal4.198204.53244K562HNRNPM
chr31261655212616610+intron-Distal,intron-Proximal4.708594.13847K562AQR
chr31259879912598889+intron-Distal4.366754.90578HepG2HNRNPM
chr31259869312598737+intron-Proximal4.206367.80986K562PRPF8
chr31261176612611800+intron-Proximal5.239116.22530K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MKRN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MKRN2 is not available on ENCORE database.

  • 79 RBPs can affect the levels of MKRN2.  








The Knockdown/knockout RNA-Seq assay for MKRN2 is not available on ENCORE database.





79 RBPs can affect the gene expression of MKRN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MKRN2ENSG00000075975.11909.428101354.24380-0.574504.488403.83300HepG2AKAP1
MKRN2ENSG00000075975.11624.177601120.52690-0.844109.783508.36540HepG2ASCC1
MKRN2ENSG00000075975.11626.834901078.63700-0.7831015.0221013.64820HepG2AUH
MKRN2ENSG00000075975.11439.42910585.57740-0.414202.959402.16400HepG2CALR
MKRN2ENSG00000075975.11714.267201064.57650-0.575705.101304.07010HepG2CIRBP
MKRN2ENSG00000075975.11576.48600689.55550-0.258402.024301.44290HepG2CKAP4
MKRN2ENSG00000075975.11574.64810847.51490-0.560602.936902.14740HepG2CNOT7
MKRN2ENSG00000075975.11850.818601030.33930-0.276202.944802.18380HepG2DAZAP1
MKRN2ENSG00000075975.11761.211801297.27150-0.769108.453007.40970HepG2DDX3X
MKRN2ENSG00000075975.11838.610501114.36320-0.410102.529001.93710HepG2DDX6
MKRN2ENSG00000075975.11736.251901071.28410-0.541104.458303.71560HepG2EIF2S1
MKRN2ENSG00000075975.11336.79860496.23700-0.559103.318502.33420HepG2EIF3D
MKRN2ENSG00000075975.11724.404201183.90440-0.708706.532805.54900HepG2EIF4A3
MKRN2ENSG00000075975.11843.103001194.48100-0.502604.076903.24860HepG2FXR1
MKRN2ENSG00000075975.11738.994401108.07150-0.584404.894704.02120HepG2G3BP1
MKRN2ENSG00000075975.11917.071301176.34010-0.359202.389501.56370HepG2G3BP2
MKRN2ENSG00000075975.11305.20700501.96900-0.717804.789503.96220HepG2GPKOW
MKRN2ENSG00000075975.11352.29740479.03590-0.443302.282401.70490HepG2HNRNPLL
MKRN2ENSG00000075975.11292.14200548.55270-0.909009.608508.01820HepG2HNRNPM
MKRN2ENSG00000075975.11443.82750667.75310-0.589307.084606.14980HepG2HNRNPU
MKRN2ENSG00000075975.11477.54270682.08930-0.514306.472405.39830HepG2ILF2
MKRN2ENSG00000075975.11718.122301194.89790-0.734607.691206.61260HepG2MAGOH
MKRN2ENSG00000075975.11693.752301229.89830-0.826009.124608.01350HepG2NCBP2
MKRN2ENSG00000075975.11509.69770775.02990-0.604603.747302.08560HepG2NKRF
MKRN2ENSG00000075975.11822.244601021.67970-0.313302.738701.97880HepG2NOL12
MKRN2ENSG00000075975.11643.359201095.32220-0.767708.122306.90220HepG2PABPC4
MKRN2ENSG00000075975.11666.697001151.95670-0.7890016.3436015.06910HepG2PCBP1
MKRN2ENSG00000075975.11453.19790595.58410-0.394203.127802.34830HepG2PPIL4
MKRN2ENSG00000075975.11746.407201172.15230-0.6511011.0552010.10330HepG2PTBP1
MKRN2ENSG00000075975.11663.37340975.26910-0.556005.741004.92350HepG2PUF60
MKRN2ENSG00000075975.11930.338601269.48410-0.448405.222804.40510HepG2QKI
MKRN2ENSG00000075975.11427.42100707.04600-0.726103.771702.95330HepG2RAVER1
MKRN2ENSG00000075975.11420.85110636.91030-0.597803.247502.09670HepG2RCC2
MKRN2ENSG00000075975.11871.041101304.49850-0.582709.696208.79490HepG2NELFE
MKRN2ENSG00000075975.11862.982101214.95310-0.493507.215606.28970HepG2RECQL
MKRN2ENSG00000075975.11532.51290723.39560-0.442002.661601.87530HepG2RPS2
MKRN2ENSG00000075975.11632.15980851.23640-0.429302.248701.52720HepG2RPS3A
MKRN2ENSG00000075975.11330.77160484.63660-0.551103.278602.25140HepG2SERBP1
MKRN2ENSG00000075975.11892.078801220.37380-0.452106.133005.31080HepG2SF3B4
MKRN2ENSG00000075975.11527.69420693.49380-0.394204.088503.33240HepG2SMN1
MKRN2ENSG00000075975.11915.213401273.80120-0.477007.122206.44680HepG2SRSF1
MKRN2ENSG00000075975.11777.05070962.91700-0.309402.935902.29180HepG2SRSF5
MKRN2ENSG00000075975.11894.702601036.30090-0.212001.792401.33100HepG2SRSF9
MKRN2ENSG00000075975.11375.99700531.07770-0.498202.672201.45410HepG2STAU1
MKRN2ENSG00000075975.11946.979301095.11830-0.209701.894601.36220HepG2SUCLG1
MKRN2ENSG00000075975.11980.483201144.92870-0.223701.808401.33620HepG2TAF15
MKRN2ENSG00000075975.11417.57030648.88130-0.635906.599105.88740HepG2TIAL1
MKRN2ENSG00000075975.11423.93980654.64500-0.626907.964407.08570HepG2TRIM56
MKRN2ENSG00000075975.11266.77170394.33190-0.563802.953401.33430HepG2TROVE2
MKRN2ENSG00000075975.11732.976701008.47540-0.460303.049402.17300HepG2UBE2L3
MKRN2ENSG00000075975.11545.32590677.02460-0.312102.562601.88640HepG2UPF1
MKRN2ENSG00000075975.11534.01260695.89060-0.382003.313302.17820HepG2UTP18
MKRN2ENSG00000075975.11542.73170762.46590-0.490402.703401.62310HepG2XPO5
MKRN2ENSG00000075975.11632.13770744.59820-0.236201.902901.42660HepG2ZNF622
MKRN2ENSG00000075975.112801.059702085.037200.425808.774807.84020K562AGGF1
MKRN2ENSG00000075975.112658.646002169.587300.293202.602601.96810K562AKAP8L
MKRN2ENSG00000075975.112722.005602240.267700.280902.207801.67390K562AQR
MKRN2ENSG00000075975.112853.443602276.441400.325804.493303.29910K562ATP5C1
MKRN2ENSG00000075975.11488.69050670.25560-0.455803.229102.07120K562CCAR1
MKRN2ENSG00000075975.112730.803801857.196500.5561013.4264012.10120K562DDX47
MKRN2ENSG00000075975.112963.517002334.558300.344105.291904.02720K562DKC1
MKRN2ENSG00000075975.111346.657501114.798600.272502.604401.83050K562EIF3G
MKRN2ENSG00000075975.111367.273801667.39460-0.286302.738602.13590K562FXR1
MKRN2ENSG00000075975.11995.376501194.34520-0.262901.834401.33630K562HNRNPC
MKRN2ENSG00000075975.111964.347801599.485800.296302.136701.43420K562HSPD1
MKRN2ENSG00000075975.112792.092702302.433600.278102.255001.52020K562KIF1C
MKRN2ENSG00000075975.111499.073201831.47770-0.288902.466501.59950K562MATR3
MKRN2ENSG00000075975.113211.349702579.312900.316103.213302.22080K562MBNL1
MKRN2ENSG00000075975.111313.405601067.427000.299101.935401.30160K562PRPF8
MKRN2ENSG00000075975.111259.439801782.99980-0.501506.634905.64130K562PTBP1
MKRN2ENSG00000075975.112621.734102151.552200.285002.213401.71660K562PUS1
MKRN2ENSG00000075975.112663.241102096.432400.345104.716303.96240K562RBM15
MKRN2ENSG00000075975.111403.194501709.71490-0.285002.113301.38350K562RBM22
MKRN2ENSG00000075975.11676.05230977.25690-0.531605.482304.07880K562RCC2
MKRN2ENSG00000075975.111974.154001087.260500.8604011.030809.37170K562RPS19
MKRN2ENSG00000075975.111646.626601091.362800.593304.475302.77240K562RRP9
MKRN2ENSG00000075975.111934.232201508.668100.358404.916703.85650K562SF3A3
MKRN2ENSG00000075975.111147.170201545.66590-0.430107.416105.96200K562SRPK2
MKRN2ENSG00000075975.111188.846801769.03080-0.573406.407305.29020K562TARDBP
MKRN2ENSG00000075975.111207.513701594.49390-0.401103.593601.76620K562TBRG4
MKRN2ENSG00000075975.111853.622201531.425300.275402.532601.76370K562U2AF2
MKRN2ENSG00000075975.111857.232701442.490300.364506.194104.98180K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MKRN2 is not available on ENCORE database.





1 RBPs can affect the splicing of MKRN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMKRN2ENSG00000075975.11chr3+1261034712610502125985851259867512611569126117510.066000.010300.08319includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MKRN2 is not avaliable on ENCORE database.