LEMD3

General Information

Gene Name       : LEMD3
Gene ID             : ENSG00000174106.2
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LEMD3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LEMD3ENSG00000174106.219.6112.0215.81ENCSR000AEF
HepG2LEMD3ENSG00000174106.26.4211.669.04ENCSR985KAT
K562LEMD3ENSG00000174106.210.8211.1811.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LEMD3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LEMD3 RNA is bound by 21 proteins.  







eCLIP assay for LEMD3 is not avaliable on ENCORE database.





21 proteins are bound to LEMD3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr126564040665640442+3'-UTR7.3766352.82500K562LIN28B
chr126564076865640816+3'-UTR4.584844.80693HepG2FUBP3
chr126564063965640681+3'-UTR4.6970923.24283K562PUM2
chr126564039365640454+3'-UTR6.1884662.21549HepG2LIN28B
chr126564192965642020+3'-UTR7.1957634.79322K562PUM2
chr126564021365640251+3'-UTR3.783188.26051K562PUM2
chr126564068165640732+3'-UTR4.2376619.38918K562PUM2
chr126564149065641536+3'-UTR3.647605.80402HepG2FUBP3
chr126564044265640465+3'-UTR5.4481010.32591K562LIN28B
chr126564176165641808+3'-UTR3.419763.40672HepG2FUBP3
chr126564187965641925+3'-UTR4.843838.44976K562PUM2
chr126564094365641002+3'-UTR4.051286.03781HepG2FUBP3
chr126564013965640205+3'-UTR3.666843.26999K562KHSRP
chr126564202565642067+3'-UTR4.366304.01944HepG2FUBP3
chr126564174465641831+3'-UTR4.8809526.82915K562PUM2
chr126564038565640406+3'-UTR6.9500034.93783K562LIN28B
chr126556419465564297+CDS,intron-Proximal4.925847.33003K562UCHL5
chr126563392065633988+CDS4.220393.02457HepG2BCLAF1
chr126556483065564896+CDS,intron-Distal4.963797.81713K562RBM15
chr126556456265564668+CDS,intron-Distal3.608056.98424K562UCHL5
chr126563379165633871+CDS,intron-Proximal3.816623.02234K562KHSRP
chr126563939465639486+CDS,intron-Proximal5.038504.40745K562SF3B4
chr126556479365564830+CDS,intron-Distal4.226407.89807K562RBM15
chr126556443465564504+CDS,intron-Distal3.203683.50696K562BUD13
chr126556344265563496+CDS4.267634.70436K562RBM15
chr126556465165564731+CDS,intron-Distal4.052153.00996K562BUD13
chr126563391365633962+CDS,intron-Proximal3.878233.66349K562LIN28B
chr126556404765564120+CDS5.6930112.00022K562UCHL5
chr126556404365564133+CDS3.300725.23342HepG2G3BP1
chr126556459965564650+CDS,intron-Distal4.367284.82934K562RBM15
chr126556485765564900+CDS,intron-Distal,intron-Proximal3.022404.14618K562ZNF622
chr126563372165633774+CDS4.081603.11168K562ZNF622
chr126556474665564793+CDS,intron-Distal4.097007.22341K562RBM15
chr126556403765564112+CDS3.163955.97777HepG2PPIG
chr126556935965569409+intron-Distal3.159304.59863HepG2PTBP1
chr126558750865587600+intron-Distal5.4021415.32107K562EIF4G2
chr126556945465569522+intron-Distal3.320743.32889K562MATR3
chr126557328165573431+intron-Distal5.888779.13109K562QKI
chr126556981565569861+intron-Distal4.188583.41738HepG2PTBP1
chr126559732465597447+intron-Distal4.652836.93191K562KHSRP
chr126559743765597500+intron-Distal3.480875.06177HepG2SUGP2
chr126556536765565424+intron-Distal4.593276.73684K562KHSRP
chr126558753565587609+intron-Distal4.258094.62276K562TARDBP
chr126556494665565025+intron-Distal,intron-Proximal4.158494.26925HepG2KHSRP
chr126556506465565144+intron-Distal4.515646.27552K562KHSRP
chr126561678365616884+intron-Distal3.193514.13575K562KHSRP
chr126561205365612160+intron-Distal3.562555.83959K562KHSRP
chr126559175565591809+intron-Distal3.341543.28806K562KHSRP
chr126559582365595870+intron-Distal3.957213.86809HepG2SUGP2
chr126559652465596638+intron-Distal3.640644.32964K562HNRNPM
chr126559650165596615+intron-Distal5.045527.51573HepG2HNRNPM
chr126556916165569277+intron-Distal5.8557512.28789HepG2PTBP1
chr126562000865620095+intron-Distal3.845386.51515K562HNRNPM
chr126556917565569294+intron-Distal4.109886.46365K562MATR3
chr126556932465569402+intron-Distal3.611673.39827HepG2MATR3
chr126556524365565338+intron-Distal3.907406.89441K562KHSRP
chr126556946165569507+intron-Distal4.843325.43236K562PTBP1
chr126559556065595627+intron-Distal4.588735.84463HepG2SUGP2
chr126558753965587596+intron-Distal3.883223.25872K562IGF2BP1
chr126561601965616086+intron-Distal3.118213.14999K562EXOSC5
chr126556934965569424+intron-Distal4.211807.80454K562PTBP1
chr126559655865596620+intron-Distal3.506984.33009HepG2SUGP2
chr126559171065591755+intron-Distal3.939003.45805K562KHSRP
chr126556981665569858+intron-Distal4.154033.90241K562MATR3
chr126563701965637074+intron-Distal,intron-Proximal4.037523.50357HepG2QKI
chr126559649165596596+intron-Distal4.677305.42507HepG2MATR3
chr126563463165634673+intron-Proximal4.023063.80778HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LEMD3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LEMD3 is not available on ENCORE database.

  • 67 RBPs can affect the levels of LEMD3.  








The Knockdown/knockout RNA-Seq assay for LEMD3 is not available on ENCORE database.





67 RBPs can affect the gene expression of LEMD3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LEMD3ENSG00000174106.2559.11720675.98310-0.273802.001201.33480HepG2AKAP8L
LEMD3ENSG00000174106.2661.75680934.27880-0.497602.863402.06560HepG2ASCC1
LEMD3ENSG00000174106.2329.56720603.24600-0.872206.304304.86340HepG2BCCIP
LEMD3ENSG00000174106.2651.66720887.61750-0.445803.063902.25230HepG2CIRBP
LEMD3ENSG00000174106.2310.74440510.65920-0.716603.423402.67540HepG2DDX21
LEMD3ENSG00000174106.2326.59410554.99970-0.765004.194902.64980HepG2DDX27
LEMD3ENSG00000174106.2384.61380593.09160-0.624803.502802.64540HepG2DDX55
LEMD3ENSG00000174106.2625.09330929.00150-0.571604.104003.36310HepG2DDX6
LEMD3ENSG00000174106.2394.23170493.09720-0.322801.975501.37040HepG2DNAJC21
LEMD3ENSG00000174106.2363.90370488.75640-0.425603.754703.01660HepG2DNAJC2
LEMD3ENSG00000174106.2260.95810405.23180-0.634903.396502.40140HepG2EIF3D
LEMD3ENSG00000174106.2724.043601035.98380-0.516904.060903.35700HepG2ETF1
LEMD3ENSG00000174106.2497.51810657.47450-0.402202.916602.06090HepG2EWSR1
LEMD3ENSG00000174106.2765.88400995.81570-0.378802.261001.63300HepG2FXR1
LEMD3ENSG00000174106.2718.32920923.90440-0.363102.072801.49330HepG2G3BP1
LEMD3ENSG00000174106.2366.61130497.82130-0.441402.635402.00240HepG2HNRNPA1
LEMD3ENSG00000174106.2404.71550553.73870-0.452302.792002.09600HepG2HNRNPC
LEMD3ENSG00000174106.2656.14500935.21150-0.511304.156303.31450HepG2HNRNPK
LEMD3ENSG00000174106.2686.24560939.17830-0.452703.149302.43450HepG2IGF2BP2
LEMD3ENSG00000174106.2355.37130561.88500-0.660908.315207.11080HepG2ILF2
LEMD3ENSG00000174106.2427.27140583.15770-0.448702.660101.47500HepG2LIN28B
LEMD3ENSG00000174106.2723.72510996.16210-0.460903.204502.49950HepG2MAGOH
LEMD3ENSG00000174106.2427.95070544.47680-0.347402.487901.68020HepG2PARN
LEMD3ENSG00000174106.2681.80800786.05170-0.205301.816401.31360HepG2PUM1
LEMD3ENSG00000174106.2725.77720931.15310-0.359503.028902.38030HepG2QKI
LEMD3ENSG00000174106.2679.30730865.90990-0.350202.245801.76560HepG2RBM22
LEMD3ENSG00000174106.2710.29160956.86300-0.429904.633103.96610HepG2NELFE
LEMD3ENSG00000174106.2368.47630544.70900-0.563904.498603.65680HepG2RPLP0
LEMD3ENSG00000174106.2239.05630394.30300-0.722005.370904.54740HepG2RPS19
LEMD3ENSG00000174106.2307.90800489.86560-0.669907.170806.20320HepG2SAFB2
LEMD3ENSG00000174106.21166.69310818.174000.511803.230802.50130HepG2SF3A3
LEMD3ENSG00000174106.2419.01330571.26160-0.447204.362303.58710HepG2SMN1
LEMD3ENSG00000174106.21219.39120978.047200.318102.969102.45600HepG2SRFBP1
LEMD3ENSG00000174106.2786.08600934.33960-0.249302.041301.61800HepG2SRSF1
LEMD3ENSG00000174106.2712.89660831.51700-0.222102.005801.45970HepG2SUCLG1
LEMD3ENSG00000174106.2362.70310590.45230-0.703004.379403.55670HepG2SUPV3L1
LEMD3ENSG00000174106.2619.53250839.85160-0.439004.484303.79680HepG2TAF15
LEMD3ENSG00000174106.2277.22540534.48620-0.9471011.5114010.61590HepG2TIAL1
LEMD3ENSG00000174106.2271.58940539.28210-0.9896014.6776013.52470HepG2TRIM56
LEMD3ENSG00000174106.2700.43950553.396700.339802.006701.46260HepG2U2AF1
LEMD3ENSG00000174106.2519.23630725.59570-0.482805.420604.49410HepG2UPF1
LEMD3ENSG00000174106.2337.56940581.23430-0.783905.693704.66670HepG2XRN2
LEMD3ENSG00000174106.2955.95590792.164300.271002.254701.73400K562AGGF1
LEMD3ENSG00000174106.22948.945601319.770701.1598027.6011025.94880K562AQR
LEMD3ENSG00000174106.2501.73030630.92890-0.330602.649601.35850K562DDX27
LEMD3ENSG00000174106.2779.01030595.981100.386302.634901.74670K562EFTUD2
LEMD3ENSG00000174106.2491.96540690.47080-0.489004.454503.45600K562EIF3G
LEMD3ENSG00000174106.21028.23100693.590800.567907.943106.98660K562FXR1
LEMD3ENSG00000174106.2895.80400658.182200.444602.490501.82550K562G3BP2
LEMD3ENSG00000174106.2918.948701286.19840-0.485104.999303.98430K562GRSF1
LEMD3ENSG00000174106.2506.86290666.31390-0.394602.117101.30970K562HNRNPM
LEMD3ENSG00000174106.2873.507001098.17840-0.330202.204701.49250K562HSPD1
LEMD3ENSG00000174106.21293.82260979.979500.400703.702102.62500K562MBNL1
LEMD3ENSG00000174106.2663.58290853.21540-0.362603.662402.74220K562MTPAP
LEMD3ENSG00000174106.21060.85430686.892400.627004.484903.27670K562NAA15
LEMD3ENSG00000174106.2727.60340947.99790-0.381704.846103.89660K562NSUN2
LEMD3ENSG00000174106.21016.07030802.928200.339602.311201.42130K562PCBP2
LEMD3ENSG00000174106.2699.23450919.61970-0.395302.888502.04850K562PPIG
LEMD3ENSG00000174106.2951.22420579.956200.713707.431806.20440K562PRPF8
LEMD3ENSG00000174106.2387.14560514.25270-0.409602.224701.42130K562PSIP1
LEMD3ENSG00000174106.22519.991801666.013200.596909.100407.60690K562PUF60
LEMD3ENSG00000174106.21630.89470817.506300.9963015.9904014.72670K562PUS1
LEMD3ENSG00000174106.21069.73860796.494500.425404.449903.71650K562RBM15
LEMD3ENSG00000174106.2359.50400469.27430-0.384402.198101.31750K562RCC2
LEMD3ENSG00000174106.2965.65780604.201800.676402.472401.36310K562SF1
LEMD3ENSG00000174106.2863.93900684.296400.336202.658201.82200K562SF3B4
LEMD3ENSG00000174106.21156.21470693.741800.736803.231301.86660K562SNRNP200
LEMD3ENSG00000174106.2370.05180494.61470-0.418602.199101.37410K562TIAL1
LEMD3ENSG00000174106.2325.35800525.55940-0.691805.755604.27760K562TRIM56
LEMD3ENSG00000174106.2898.11230658.830100.446904.287003.29100K562U2AF2
LEMD3ENSG00000174106.2854.924101005.18240-0.233602.030601.40920K562UPF1
LEMD3ENSG00000174106.2602.38730860.10270-0.513805.007103.81430K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LEMD3 is not available on ENCORE database.





13 RBPs can affect the splicing of LEMD3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELEMD3ENSG00000174106.2chr12+656394486563955465637144656372496563964065639719-0.190000.000000.00000excludedK562AQR
A3SSLEMD3ENSG00000174106.2chr12+6563369265633810656337086563381065632448656325940.170000.000000.00000longerK562AQR
A3SSLEMD3ENSG00000174106.2chr12+6563464065634867656346886563486765633915656340180.070000.000090.00077longerK562AQR
A3SSLEMD3ENSG00000174106.2chr12+656394486563971965639640656397196563714465637249-0.333000.000000.00001shorterK562AQR
A5SSLEMD3ENSG00000174106.2chr12+6563391565634133656339156563401865634688656348670.097000.000000.00000longerK562AQR
RILEMD3ENSG00000174106.2chr12+656394486563971965639448656395546563964065639719-0.086000.001040.06821excludedK562NONO
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.123000.000820.05614includedHepG2DDX6
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.424000.000000.00000includedK562PUS1
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.112000.017630.09649includedHepG2U2AF2
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.193000.000230.00374includedK562AGGF1
RILEMD3ENSG00000174106.2chr12+656394486563971965639448656395546563964065639719-0.091000.000550.04905excludedK562XRN2
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.281000.001600.01683includedK562AKAP8L
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.199000.000440.00641includedK562RBM15
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.062000.016980.09563includedHepG2SF3B4
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.184000.000110.00230includedK562UTP18
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.185000.000000.00000includedK562AQR
RILEMD3ENSG00000174106.2chr12+6563944865639719656394486563955465639640656397190.180000.000620.04613includedK562LARP4
MXELEMD3ENSG00000174106.2chr12+65637167656372496563944865639554656346886563486765639640656397190.141000.003110.024141includedK562AQR
MXELEMD3ENSG00000174106.2chr12+65637144656372496563944865639554656346886563486765639640656397190.207000.000000.000001includedK562AQR
MXELEMD3ENSG00000174106.2chr12+65637129656372496563944865639554656346886563486765639640656397190.216000.000000.000001includedK562AQR
MXELEMD3ENSG00000174106.2chr12+65637066656372496563944865639554656346886563486765639640656397190.207000.000000.000001includedK562AQR
MXELEMD3ENSG00000174106.2chr12+65637016656372496563944865639554656346886563486765639640656397190.216000.000000.000001includedK562AQR
MXELEMD3ENSG00000174106.2chr12+6563944865639554656396116563971965637144656372496563994165642107-0.130000.004390.032212includedK562AQR
MXELEMD3ENSG00000174106.2chr12+6563944865639554656396406563971965637167656372496563994165642107-0.136000.001910.016052includedK562AQR
MXELEMD3ENSG00000174106.2chr12+6563244865632594656337086563381065632281656323616563391565634018-0.215000.008920.089452includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LEMD3 is not avaliable on ENCORE database.