KLHL12

General Information

Gene Name       : KLHL12
Gene ID             : ENSG00000117153.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: KLHL12)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KLHL12ENSG00000117153.1524.2221.8423.03ENCSR000AEF
HepG2KLHL12ENSG00000117153.1514.7317.5316.13ENCSR985KAT
K562KLHL12ENSG00000117153.1527.0027.1827.09ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KLHL12 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KLHL12 RNA is bound by 8 proteins.  







eCLIP assay for KLHL12 is not avaliable on ENCORE database.





8 proteins are bound to KLHL12 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1202860896202860950-3'-UTR,intron-Distal3.934184.87320K562UPF1
chr1202861467202861523-3'-UTR,intron-Distal,intron-Proximal3.983694.88658HepG2SUB1
chr1202860991202861018-3'-UTR,intron-Distal3.239893.06830K562UPF1
chr1202860248202860330-3'-UTR,intron-Distal5.558415.77554K562CPEB4
chr1202860744202860812-3'-UTR,intron-Distal5.5323710.90122K562UPF1
chr1202861122202861215-3'-UTR,intron-Distal3.030959.28267K562UPF1
chr1202896216202896320-5'-UTR,intron-Distal4.292475.48791HepG2DDX3X
chr1202896214202896340-5'-UTR,intron-Distal5.3180410.52516K562DDX3X
chr1202878233202878309-5'-UTR,CDS,intron-Distal,intron-Proximal4.8413610.89051K562SF3B4
chr1202878270202878329-5'-UTR,intron-Distal,intron-Proximal3.694063.02234K562KHSRP
chr1202865981202866043-CDS,intron-Distal,intron-Proximal3.180533.86052K562YBX3
chr1202894167202894244-CDS,intron-Distal3.849907.40140K562YBX3
chr1202887232202887316-CDS,intron-Distal,intron-Proximal3.550725.32296K562PRPF8
chr1202879206202879380-intron-Distal3.105966.60316K562KHSRP
chr1202880043202880151-intron-Distal,intron-Proximal3.067873.46531K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KLHL12 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KLHL12 is not available on ENCORE database.

  • 68 RBPs can affect the levels of KLHL12.  








The Knockdown/knockout RNA-Seq assay for KLHL12 is not available on ENCORE database.





68 RBPs can affect the gene expression of KLHL12 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KLHL12ENSG00000117153.11630.68020459.801600.455803.142402.00760HepG2AATF
KLHL12ENSG00000117153.11913.10330535.142000.7708014.5759013.41350HepG2ACO1
KLHL12ENSG00000117153.111826.99100677.079801.4320024.1660022.76330HepG2AKAP1
KLHL12ENSG00000117153.11738.04600560.217900.397602.363501.63350HepG2ASCC1
KLHL12ENSG00000117153.111115.48730932.213000.258802.253301.62220HepG2AUH
KLHL12ENSG00000117153.11424.54630624.02760-0.555703.078202.08850HepG2BCCIP
KLHL12ENSG00000117153.11819.41040532.248400.622405.284604.23350HepG2CIRBP
KLHL12ENSG00000117153.11700.24240843.55430-0.268602.292501.60920HepG2DAZAP1
KLHL12ENSG00000117153.11646.89630494.910500.386303.892502.92460HepG2DDX19B
KLHL12ENSG00000117153.11871.80500507.315100.781009.201208.03950HepG2DDX21
KLHL12ENSG00000117153.11985.52550648.572500.603505.042604.21980HepG2DDX3X
KLHL12ENSG00000117153.11726.86430557.181300.383401.981401.45150HepG2DDX6
KLHL12ENSG00000117153.11701.15620539.430500.378203.208602.45650HepG2DNAJC21
KLHL12ENSG00000117153.11362.65860535.58810-0.562503.514002.85000HepG2EIF2S1
KLHL12ENSG00000117153.11921.60260591.866600.638805.090504.22520HepG2EIF4A3
KLHL12ENSG00000117153.11656.56870832.27880-0.342102.975702.11350HepG2EIF4G1
KLHL12ENSG00000117153.11483.53390797.25900-0.721407.143605.86080HepG2EIF4G2
KLHL12ENSG00000117153.111326.242401070.357800.309203.398302.74180HepG2ETF1
KLHL12ENSG00000117153.11962.14220551.274800.803406.536305.40390HepG2FIP1L1
KLHL12ENSG00000117153.11753.26630553.987200.443202.725802.06470HepG2G3BP1
KLHL12ENSG00000117153.11567.86700772.84530-0.444604.611103.71390HepG2HNRNPF
KLHL12ENSG00000117153.11634.71680768.39210-0.275702.257501.64010HepG2HNRNPL
KLHL12ENSG00000117153.11562.87550761.03430-0.435103.711202.88320HepG2IGF2BP1
KLHL12ENSG00000117153.11827.26470597.441500.469503.188702.48480HepG2MAGOH
KLHL12ENSG00000117153.11646.68130446.013000.535903.991803.02420HepG2MSI2
KLHL12ENSG00000117153.11310.51170432.47310-0.478002.493501.78270HepG2NSUN2
KLHL12ENSG00000117153.11872.85290547.585700.672605.947704.89970HepG2PABPC4
KLHL12ENSG00000117153.11657.14190533.650100.300202.252501.69460HepG2PCBP1
KLHL12ENSG00000117153.11639.22540489.886400.383803.272302.43770HepG2PRPF4
KLHL12ENSG00000117153.11613.98750473.356800.375202.092501.38600HepG2PRPF8
KLHL12ENSG00000117153.11785.32380543.012600.532205.913105.17420HepG2PTBP1
KLHL12ENSG00000117153.11612.74030798.50380-0.382002.660502.07440HepG2PUF60
KLHL12ENSG00000117153.11589.88730847.03650-0.522005.119104.22050HepG2PUM2
KLHL12ENSG00000117153.11747.43300545.070700.455405.152004.35880HepG2PUS1
KLHL12ENSG00000117153.11752.93560588.088300.356402.672602.05730HepG2QKI
KLHL12ENSG00000117153.111338.53610894.610100.581208.648707.85130HepG2RBM22
KLHL12ENSG00000117153.11320.66410468.25400-0.546202.768901.98200HepG2RRP9
KLHL12ENSG00000117153.111380.310701010.409800.450006.969006.27430HepG2SRFBP1
KLHL12ENSG00000117153.111046.39570590.094900.8263015.8152014.88190HepG2SRSF1
KLHL12ENSG00000117153.11941.02130788.433600.255102.238201.66810HepG2SRSF5
KLHL12ENSG00000117153.11556.64120759.28730-0.447904.600703.73660HepG2SRSF7
KLHL12ENSG00000117153.11602.13620480.075900.326702.594002.05600HepG2SRSF9
KLHL12ENSG00000117153.111026.02670877.241200.225901.847301.40680HepG2SSB
KLHL12ENSG00000117153.11707.56230485.743800.542603.101701.69310HepG2SUGP2
KLHL12ENSG00000117153.11814.14300610.785100.414502.462201.81940HepG2SUPV3L1
KLHL12ENSG00000117153.11306.30550475.39190-0.634104.448603.55620HepG2TARDBP
KLHL12ENSG00000117153.11890.35440584.653900.606707.219206.48070HepG2TIAL1
KLHL12ENSG00000117153.11630.32900471.492800.418802.275201.70000HepG2U2AF1
KLHL12ENSG00000117153.11489.57270825.79220-0.754305.759004.52230HepG2UBE2L3
KLHL12ENSG00000117153.11250.20680360.82190-0.528202.727401.97250HepG2UCHL5
KLHL12ENSG00000117153.11727.21150447.324200.701009.587008.58110HepG2UTP3
KLHL12ENSG00000117153.11707.73680509.570900.473805.699604.98810HepG2ZNF622
KLHL12ENSG00000117153.11366.08250526.10400-0.523202.764601.46980HepG2ZRANB2
KLHL12ENSG00000117153.111555.581501896.49540-0.285902.198801.61450K562AKAP8L
KLHL12ENSG00000117153.111137.456501584.32000-0.478106.918704.71950K562BCCIP
KLHL12ENSG00000117153.114216.470903418.868200.302403.312602.24540K562CELF1
KLHL12ENSG00000117153.111902.682301614.022700.237302.585001.41620K562DDX21
KLHL12ENSG00000117153.11957.709901342.53480-0.487305.548303.67610K562DDX27
KLHL12ENSG00000117153.11943.228101319.15180-0.483904.333103.17310K562EFTUD2
KLHL12ENSG00000117153.111252.616501663.66060-0.409405.696604.71940K562EIF2S2
KLHL12ENSG00000117153.11990.619301313.97610-0.407503.589602.65800K562EIF4A3
KLHL12ENSG00000117153.11864.845501183.32350-0.452305.443803.74260K562EIF4B
KLHL12ENSG00000117153.111644.894301263.221400.380803.331002.39440K562FIP1L1
KLHL12ENSG00000117153.11964.144601214.20940-0.332702.648602.06260K562HNRNPC
KLHL12ENSG00000117153.111902.546801577.139400.270504.403403.48670K562NSUN2
KLHL12ENSG00000117153.111076.314301522.87370-0.500705.454704.07100K562PCBP2
KLHL12ENSG00000117153.111262.994601054.351500.260402.078901.38440K562POLR2G
KLHL12ENSG00000117153.11987.627501283.68690-0.378302.776302.02630K562PRPF8
KLHL12ENSG00000117153.11797.881701088.67750-0.448303.806902.72150K562PSIP1
KLHL12ENSG00000117153.112743.086603161.30310-0.204702.322901.44200K562PUM2
KLHL12ENSG00000117153.111084.701901594.58920-0.555906.416405.06650K562RBM22
KLHL12ENSG00000117153.111167.212401678.01900-0.523705.323403.74460K562NELFE
KLHL12ENSG00000117153.11958.505901473.56690-0.620502.434901.31470K562SNRNP200
KLHL12ENSG00000117153.111873.013601594.494800.232203.012902.04300K562SRPK2
KLHL12ENSG00000117153.112088.110901657.407600.333202.673301.34220K562SSRP1
KLHL12ENSG00000117153.111289.159901649.82800-0.355902.785402.07600K562TARDBP
KLHL12ENSG00000117153.112639.680403420.36660-0.373804.622402.81640K562UBE2L3
KLHL12ENSG00000117153.11954.408601315.43450-0.462903.866002.64410K562UCHL5
KLHL12ENSG00000117153.111336.750201672.27910-0.323104.429403.54240K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KLHL12 is not available on ENCORE database.





6 RBPs can affect the splicing of KLHL12 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKLHL12ENSG00000117153.11chr1-2028848582028849002028801812028803312028872982028875160.070000.001120.02303includedK562SRSF1
SEKLHL12ENSG00000117153.11chr1-202862366202862553202860227202861787202863311202863410-0.173000.000370.00919excludedK562SF3B4
SEKLHL12ENSG00000117153.11chr1-2028848582028849002028801812028803312028872982028875160.133000.000000.00024includedK562PRPF8
SEKLHL12ENSG00000117153.11chr1-2028848582028849002028801812028803312028872982028875160.103000.000040.00365includedK562EFTUD2
SEKLHL12ENSG00000117153.11chr1-202862366202862553202860227202861787202863311202863410-0.192000.000090.02390excludedK562EIF3G
SEKLHL12ENSG00000117153.11chr1-202862366202862472202860227202861787202863311202863410-0.317000.000540.09988excludedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KLHL12 is not avaliable on ENCORE database.