INTS8

General Information

Gene Name       : INTS8
Gene ID             : ENSG00000164941.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: INTS8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878INTS8ENSG00000164941.1364.1538.3851.27ENCSR000AEF
HepG2INTS8ENSG00000164941.1320.3035.1727.73ENCSR985KAT
K562INTS8ENSG00000164941.1372.7773.5373.15ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for INTS8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • INTS8 RNA is bound by 15 proteins.  







eCLIP assay for INTS8 is not avaliable on ENCORE database.





15 proteins are bound to INTS8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr89587853195878581+3'-UTR,CDS,intron-Distal,intron-Proximal3.706664.21358HepG2U2AF2
chr89587173795871760+3'-UTR,CDS,intron-Proximal3.512874.09885HepG2BCLAF1
chr89588840795888527+3'-UTR,CDS,intron-Proximal3.331279.37959K562EFTUD2
chr89587939195879446+3'-UTR,CDS,intron-Proximal3.524574.79829K562EFTUD2
chr89587853295878544+3'-UTR,CDS,intron-Distal,intron-Proximal3.476837.34430K562PRPF8
chr89587837595878461+3'-UTR,CDS,intron-Distal,intron-Proximal3.780525.32227K562EFTUD2
chr89587854495878580+3'-UTR,CDS,intron-Distal,intron-Proximal3.6469110.27068K562PRPF8
chr89587177695871798+3'-UTR,CDS3.330019.09662K562YBX3
chr89587179895871861+3'-UTR,CDS,intron-Proximal3.6767212.44888K562YBX3
chr89587932395879378+3'-UTR,CDS,intron-Proximal5.419425.90023K562SF3B4
chr89587939695879453+3'-UTR,CDS,intron-Proximal3.237425.75838K562PRPF8
chr89588411095884164+3'-UTR,CDS,intron-Proximal3.912703.20743HepG2PPIG
chr89588559395885701+3'-UTR,CDS,intron-Proximal3.562487.14018K562BUD13
chr89587183895871921+3'-UTR,CDS,intron-Proximal3.390654.30679K562KHSRP
chr89588847595888514+3'-UTR,CDS,intron-Proximal3.837625.06180HepG2BCLAF1
chr89588557095885610+3'-UTR,CDS,intron-Proximal4.739114.48002K562AQR
chr89588840595888465+3'-UTR,CDS,intron-Proximal3.911575.02403K562SF3B4
chr89587853295878591+3'-UTR,CDS,intron-Distal,intron-Proximal4.056924.89971K562U2AF2
chr89586222395862311+5'-UTR,CDS3.817306.81385HepG2BCLAF1
chr89586214295862179+5'-UTR,CDS,intron-Proximal3.756604.51739HepG2BCLAF1
chr89586377895863821+5'-UTR,CDS,intron-Proximal3.028703.25772K562ZNF622
chr89583553195835605+5'-UTR,intron-Distal,intron-Proximal4.398143.98935HepG2NCBP2
chr89585074895850821+5'-UTR,CDS5.342128.75808HepG2BCLAF1
chr89585373295853812+5'-UTR,CDS3.669116.39464HepG2BCLAF1
chr89586384995863912+5'-UTR,CDS3.872827.23562HepG2BCLAF1
chr89585375195853814+5'-UTR,CDS3.934013.43253K562YBX3
chr89584436295844405+CDS,intron-Proximal4.033785.36555HepG2BCLAF1
chr89584422395844303+CDS3.996188.08603HepG2BCLAF1
chr89584431895844362+CDS5.033786.37937HepG2BCLAF1
chr89584875195848808+CDS,intron-Proximal6.2376921.58741K562LIN28B
chr89587469495874926+intron-Distal3.055294.74233K562TARDBP
chr89586183495861901+intron-Distal,intron-Proximal4.308433.85435K562PRPF8
chr89586570795865784+intron-Distal3.389803.90146K562KHSRP
chr89586578595865934+intron-Distal,intron-Proximal4.0300612.30466K562KHSRP
chr89587843395878483+intron-Distal,intron-Proximal5.035845.26064K562AQR
chr89583974195839867+intron-Distal,intron-Proximal4.024843.24603K562KHSRP
chr89586564595865705+intron-Distal3.017773.07751K562KHSRP
chr89584906995849169+intron-Distal4.776056.27552K562KHSRP
chr89588918795889357+intron-Distal3.931943.33944K562MATR3
chr89587192195871972+intron-Distal,intron-Proximal4.138554.10688K562KHSRP
chr89583963795839689+intron-Distal,intron-Proximal4.892345.17615K562AQR
chr89583964395839765+intron-Distal,intron-Proximal4.944946.08021K562PRPF8
chr89584531595845393+intron-Distal3.749743.24603K562KHSRP
chr89587844695878480+intron-Distal,intron-Proximal4.458624.58968K562PRPF8
chr89587859295878641+intron-Distal,intron-Proximal3.166144.48980K562PRPF8
chr89586593495866004+intron-Proximal4.593276.73684K562KHSRP
chr89584002295840069+intron-Proximal5.049854.65563K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for INTS8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for INTS8 is not available on ENCORE database.

  • 79 RBPs can affect the levels of INTS8.  








The Knockdown/knockout RNA-Seq assay for INTS8 is not available on ENCORE database.





79 RBPs can affect the gene expression of INTS8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
INTS8ENSG00000164941.9474.76810646.93400-0.446402.577001.61490HepG2ADAR
INTS8ENSG00000164941.9412.86410660.33310-0.677505.361804.28600HepG2ASCC1
INTS8ENSG00000164941.9657.28890878.22490-0.418104.483503.64550HepG2AUH
INTS8ENSG00000164941.9298.04310493.71460-0.728204.610103.47390HepG2BCLAF1
INTS8ENSG00000164941.9587.32130798.29220-0.442803.305002.65770HepG2BOP1
INTS8ENSG00000164941.9451.20200575.25910-0.350402.910102.23220HepG2CKAP4
INTS8ENSG00000164941.9455.52020732.86980-0.686006.117105.12880HepG2CPSF6
INTS8ENSG00000164941.9498.01870663.42850-0.413703.460402.32030HepG2YBX3
INTS8ENSG00000164941.9651.58530827.54630-0.344903.070402.40020HepG2CELF1
INTS8ENSG00000164941.9607.57920889.82790-0.550508.342907.16260HepG2DAZAP1
INTS8ENSG00000164941.9392.90390558.57020-0.507602.334301.61750HepG2DDX55
INTS8ENSG00000164941.9563.46940832.22950-0.562602.650401.69510HepG2DDX59
INTS8ENSG00000164941.9500.31790656.60910-0.392201.940401.41460HepG2DDX6
INTS8ENSG00000164941.9437.11750628.30040-0.523404.115702.93470HepG2DHX30
INTS8ENSG00000164941.9477.82210651.42080-0.447104.032303.19700HepG2DNAJC21
INTS8ENSG00000164941.9460.18360645.69220-0.488605.619904.73800HepG2DNAJC2
INTS8ENSG00000164941.9462.86360622.53580-0.427602.433601.56640HepG2EEF2
INTS8ENSG00000164941.9614.230101008.32470-0.7151012.0055010.89640HepG2ETF1
INTS8ENSG00000164941.9449.54500630.35800-0.487702.458901.40400HepG2FUS
INTS8ENSG00000164941.9453.39600830.74890-0.873608.606507.52070HepG2GPKOW
INTS8ENSG00000164941.9525.82840731.53510-0.476303.531602.75590HepG2HNRNPC
INTS8ENSG00000164941.9529.43810724.21320-0.452004.672903.77120HepG2HNRNPF
INTS8ENSG00000164941.9495.75200810.56890-0.7093012.2065010.88660HepG2HNRNPL
INTS8ENSG00000164941.9512.73660792.80040-0.628705.317004.47490HepG2HNRNPLL
INTS8ENSG00000164941.9386.54450726.69800-0.9107015.6543014.30910HepG2HNRNPU
INTS8ENSG00000164941.9510.30530713.14190-0.482804.265603.38340HepG2IGF2BP1
INTS8ENSG00000164941.9565.03780742.29660-0.393603.872303.02000HepG2ILF2
INTS8ENSG00000164941.9857.129801244.35270-0.537802.481301.69650HepG2LARP4
INTS8ENSG00000164941.9524.41250724.74790-0.466802.825202.18500HepG2NCBP2
INTS8ENSG00000164941.9578.04260882.35080-0.610207.586706.34170HepG2NOL12
INTS8ENSG00000164941.9236.04300377.76680-0.678403.145901.44290HepG2PA2G4
INTS8ENSG00000164941.9443.14600676.10790-0.609502.933402.01890HepG2PABPC1
INTS8ENSG00000164941.9549.63200719.29680-0.388103.541802.59500HepG2PARN
INTS8ENSG00000164941.9416.68340625.26300-0.585506.583405.70850HepG2PCBP1
INTS8ENSG00000164941.9288.94480417.91220-0.532403.726302.29610HepG2PKM
INTS8ENSG00000164941.9496.18500636.21930-0.358603.079402.50790HepG2PTBP1
INTS8ENSG00000164941.9422.78830842.27760-0.9944014.3318013.11750HepG2PUF60
INTS8ENSG00000164941.9639.13900894.11080-0.484306.977806.12470HepG2PUM1
INTS8ENSG00000164941.9592.65960893.46030-0.592206.771005.73800HepG2PUM2
INTS8ENSG00000164941.9466.87790586.09190-0.328102.567601.96810HepG2PUS1
INTS8ENSG00000164941.9501.90090680.97360-0.440202.452901.52520HepG2RBM27
INTS8ENSG00000164941.9373.64620491.73990-0.396202.315601.74780HepG2RPS19
INTS8ENSG00000164941.9455.80240628.07390-0.462502.665701.87880HepG2RPS2
INTS8ENSG00000164941.9543.19160742.71680-0.451402.360801.61890HepG2RPS3A
INTS8ENSG00000164941.9329.27920493.51490-0.583803.752602.65560HepG2SERBP1
INTS8ENSG00000164941.9542.43450662.40290-0.288301.994301.47910HepG2SF3B4
INTS8ENSG00000164941.9572.71050807.60460-0.495806.329305.33670HepG2SLBP
INTS8ENSG00000164941.9638.60780754.68090-0.240902.024501.46120HepG2SMN1
INTS8ENSG00000164941.9796.22310951.87790-0.257602.146401.68750HepG2SRFBP1
INTS8ENSG00000164941.9519.36240691.39850-0.412803.711703.18440HepG2SRSF1
INTS8ENSG00000164941.9561.04950831.62160-0.567807.370106.41540HepG2SRSF5
INTS8ENSG00000164941.9338.12820711.52020-1.0733019.7073018.15880HepG2SRSF7
INTS8ENSG00000164941.9454.36040562.48370-0.308002.242601.73480HepG2SRSF9
INTS8ENSG00000164941.9607.82610826.45220-0.443305.062604.40950HepG2SSB
INTS8ENSG00000164941.9748.97060945.78700-0.336603.642202.94690HepG2SUCLG1
INTS8ENSG00000164941.9277.13150556.08820-1.004707.718706.68200HepG2SUPV3L1
INTS8ENSG00000164941.9565.05200772.77780-0.451703.286202.50300HepG2TARDBP
INTS8ENSG00000164941.9325.16200706.09340-1.1187018.2288017.15350HepG2TIAL1
INTS8ENSG00000164941.9540.67590712.43710-0.398003.845403.20310HepG2TRIM56
INTS8ENSG00000164941.9568.34820822.86290-0.533905.027303.81290HepG2TUFM
INTS8ENSG00000164941.9365.93180532.27830-0.540605.542104.64320HepG2ZC3H8
INTS8ENSG00000164941.9904.64400673.659100.425205.656104.94600HepG2ZNF622
INTS8ENSG00000164941.92353.667103398.19820-0.529906.784405.93110K562AQR
INTS8ENSG00000164941.93652.050903188.578900.195702.268601.48660K562DKC1
INTS8ENSG00000164941.91259.694101586.47280-0.332702.347801.50890K562EFTUD2
INTS8ENSG00000164941.91841.199902170.52690-0.237402.632701.45990K562EIF2S1
INTS8ENSG00000164941.91351.564802064.47860-0.611108.291506.87150K562EIF4A3
INTS8ENSG00000164941.91446.393301859.18240-0.362204.384602.87380K562EIF4B
INTS8ENSG00000164941.91460.250601802.08440-0.303503.044401.67330K562EWSR1
INTS8ENSG00000164941.91426.709602146.97220-0.5896012.0458010.87500K562FXR1
INTS8ENSG00000164941.92402.963003003.18540-0.321703.192602.38320K562GRSF1
INTS8ENSG00000164941.91178.144702096.30620-0.8313015.7837014.44130K562HNRNPC
INTS8ENSG00000164941.92593.126303181.40410-0.295002.842901.76890K562HNRNPL
INTS8ENSG00000164941.93823.922203144.719900.282002.665601.85800K562KIF1C
INTS8ENSG00000164941.91823.299102569.62650-0.495004.910903.78340K562MAGOH
INTS8ENSG00000164941.91233.500301543.81680-0.323702.211801.53730K562PRPF8
INTS8ENSG00000164941.91391.622401879.51880-0.433604.191303.04420K562PSIP1
INTS8ENSG00000164941.91802.003702496.46820-0.470304.532703.70320K562PTBP1
INTS8ENSG00000164941.93671.967802938.617100.321302.745002.20340K562PUS1
INTS8ENSG00000164941.93291.956702863.372500.201102.097701.56830K562RBM15
INTS8ENSG00000164941.91779.480702394.43510-0.428203.072202.18210K562RBM22
INTS8ENSG00000164941.91830.902602446.48250-0.418205.694904.43850K562SF3B4
INTS8ENSG00000164941.91283.348701625.44100-0.340902.751701.73040K562SRFBP1
INTS8ENSG00000164941.91533.012802447.24370-0.674806.667605.57850K562SRSF1
INTS8ENSG00000164941.91617.325202105.45410-0.380503.093701.96560K562SRSF4
INTS8ENSG00000164941.91660.820502477.04490-0.576705.389004.38450K562TARDBP
INTS8ENSG00000164941.91740.604502389.31740-0.457004.363603.29910K562TIA1
INTS8ENSG00000164941.91514.793701920.34830-0.342202.953101.97010K562TRIM56
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for INTS8 is not available on ENCORE database.





25 RBPs can affect the splicing of INTS8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.200000.000000.00000excludedK562SF3B4
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.093000.001340.04644excludedK562PRPF8
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.053000.005540.05057excludedK562AQR
SEINTS8ENSG00000164941.9chr8+958883019588837595885601958857059588844895888513-0.126000.000030.00094excludedK562PUS1
SEINTS8ENSG00000164941.9chr8+958371209583729595835534958357899583994995840021-0.105000.003490.04709excludedK562PUS1
SEINTS8ENSG00000164941.9chr8+9588677995886830958856019588570595888301958883750.089000.000190.03801includedK562LARP4
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.110000.000300.02029excludedK562EFTUD2
SEINTS8ENSG00000164941.9chr8+958506909585084695844219958444029585371895853819-0.139000.001630.03350excludedK562U2AF1
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.098000.000030.00108excludedK562U2AF1
SEINTS8ENSG00000164941.9chr8+958621439586231995861689958617609586378095863914-0.153000.000090.01530excludedHepG2SSB
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.072000.000830.01704excludedK562U2AF2
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.134000.000010.00067excludedK562HNRNPU
SEINTS8ENSG00000164941.9chr8+958867799588683095885601958857059588830195888375-0.221000.000170.01002excludedK562SF3B1
SEINTS8ENSG00000164941.9chr8+9587853995878669958783859587841995879367958795650.119000.000120.00309includedK562HNRNPC
SEINTS8ENSG00000164941.9chr8+958545749585471695853718958538199586168995861760-0.110000.000000.00001excludedK562HNRNPC
A3SSINTS8ENSG00000164941.9chr8+9587934395879565958793679587956595878385958784190.071000.019200.09209longerK562AQR
A5SSINTS8ENSG00000164941.9chr8+9588560195885805958856019588570595886779958868300.096000.000000.00006longerK562AQR
RIINTS8ENSG00000164941.9chr8+9587936795879565958793679587942495879503958795650.149000.000000.00000includedK562PUS1
RIINTS8ENSG00000164941.9chr8+9587936795879565958793679587942495879503958795650.061000.000170.02300includedK562NSUN2
RIINTS8ENSG00000164941.9chr8+958793679587956595879367958794249587950395879565-0.054000.000880.02214excludedK562RBM22
RIINTS8ENSG00000164941.9chr8+9587936795879565958793679587942495879503958795650.053000.000770.05094includedK562WDR3
RIINTS8ENSG00000164941.9chr8+9587936795879565958793679587942495879503958795650.069000.000070.00131includedK562RBM15
RIINTS8ENSG00000164941.9chr8+9587936795879565958793679587942495879503958795650.061000.000630.00982includedK562UTP18
RIINTS8ENSG00000164941.9chr8+9587934395879554958793439587942495879503958795540.078000.000000.00001includedK562AQR
RIINTS8ENSG00000164941.9chr8+9588831995888513958883199588837595888448958885130.068000.000120.00093includedK562AQR
RIINTS8ENSG00000164941.9chr8+958793679587956595879367958794249587950395879565-0.136000.000470.03105excludedHepG2LARP4
MXEINTS8ENSG00000164941.9chr8+95848751958488599585069095850846958442199584440295853718958538190.105000.004410.093361includedK562UCHL5
MXEINTS8ENSG00000164941.9chr8+9587173895871860958777339587791895869004958692069587838595878419-0.176000.003570.043062includedK562DROSHA
MXEINTS8ENSG00000164941.9chr8+9585072195850846958537189585381995848751958488599585457495854716-0.066000.002650.040882includedK562U2AF1
MXEINTS8ENSG00000164941.9chr8+95886614958868309588830195888375958856019588570595888448958885130.054000.003720.052321includedK562SRSF1
MXEINTS8ENSG00000164941.9chr8+95848751958488599585069095850846958442199584440295853718958538190.170000.000010.001831includedK562NCBP2
MXEINTS8ENSG00000164941.9chr8+95848751958488599585069095850846958442199584440295853718958538190.111000.000900.036321includedK562TAF15
MXEINTS8ENSG00000164941.9chr8+95848751958488599585069095850846958442199584440295853718958538190.131000.001150.060441includedK562HNRNPK
MXEINTS8ENSG00000164941.9chr8+9584875195848859958507219585084695844219958444029585371895853819-0.073000.002480.079312includedK562AKAP8L
MXEINTS8ENSG00000164941.9chr8+95848751958488599585069095850846958442199584440295853718958538190.153000.000260.026341includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for INTS8 is not avaliable on ENCORE database.