HSPB11

General Information

Gene Name       : HSPB11
Gene ID             : ENSG00000081870.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HSPB11)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HSPB11ENSG00000081870.11108.2886.7597.52ENCSR000AEF
HepG2HSPB11ENSG00000081870.1126.9957.2642.12ENCSR985KAT
K562HSPB11ENSG00000081870.11113.60102.76108.18ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HSPB11 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HSPB11 RNA is bound by 10 proteins.  







eCLIP assay for HSPB11 is not avaliable on ENCORE database.





10 proteins are bound to HSPB11 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr15439557754395628-3'-UTR,intron-Distal,intron-Proximal4.226084.33574K562U2AF2
chr15439563254395677-3'-UTR,intron-Distal,intron-Proximal3.839658.46423K562PRPF8
chr15439557754395627-3'-UTR,intron-Distal,intron-Proximal3.9366010.33238K562PRPF8
chr15439555354395576-3'-UTR,intron-Distal5.469398.12400K562PRPF8
chr15438949254389557-3'-UTR,intron-Distal,intron-Proximal4.127147.35008K562PRPF8
chr15439562854395678-3'-UTR,intron-Distal,intron-Proximal5.0163615.05694K562EFTUD2
chr15439558254395634-3'-UTR,intron-Distal,intron-Proximal3.894793.31221K562U2AF1
chr15439550054395553-3'-UTR,intron-Distal4.7365013.72751K562PRPF8
chr15439552254395577-3'-UTR,intron-Distal4.109548.02891K562EFTUD2
chr15439557754395628-3'-UTR,intron-Distal,intron-Proximal3.4911613.52450K562EFTUD2
chr15440566854405771-5'-UTR,CDS,intron-Distal,intron-Proximal3.4316429.56743K562DDX3X
chr15441119754411290-5'-UTR,intron-Distal,intron-Proximal4.052763.45994HepG2NCBP2
chr15441147054411526-5'-UTR,intron-Distal4.427414.86316HepG2FAM120A
chr15441123354411319-5'-UTR,intron-Distal,intron-Proximal6.034268.23278HepG2DDX3X
chr15441122654411346-5'-UTR,intron-Distal,intron-Proximal4.1968140.43654K562DDX3X
chr15438738254387453-CDS,intron-Distal3.336504.66154K562U2AF2
chr15439402254394068-CDS,intron-Distal,intron-Proximal3.363615.89548K562EFTUD2
chr15438765954387736-intron-Distal4.077313.82619K562ILF3
chr15439485654394883-intron-Distal3.912395.84589K562EFTUD2
chr15438829954388413-intron-Distal3.623058.86182K562TIA1
chr15438962254389670-intron-Distal,intron-Proximal5.240909.04180K562SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HSPB11 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HSPB11 is not available on ENCORE database.

  • 73 RBPs can affect the levels of HSPB11.  








The Knockdown/knockout RNA-Seq assay for HSPB11 is not available on ENCORE database.





73 RBPs can affect the gene expression of HSPB11 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HSPB11ENSG00000081870.7151.01580514.59060-1.7687025.3937023.87990HepG2BOP1
HSPB11ENSG00000081870.7252.10810329.26730-0.385202.265001.65420HepG2CKAP4
HSPB11ENSG00000081870.7321.73960472.42940-0.554203.447302.68750HepG2CPSF6
HSPB11ENSG00000081870.7280.59290618.39020-1.1400015.0763013.58510HepG2DAZAP1
HSPB11ENSG00000081870.7481.95740300.532600.681305.317604.40840HepG2DDX21
HSPB11ENSG00000081870.7313.27080536.47590-0.776102.688901.72730HepG2DDX59
HSPB11ENSG00000081870.7163.73250302.72240-0.886704.972304.16610HepG2DDX6
HSPB11ENSG00000081870.7201.59580341.75940-0.761507.113806.13640HepG2DNAJC2
HSPB11ENSG00000081870.7190.38310313.13280-0.717903.200402.46310HepG2EIF4B
HSPB11ENSG00000081870.7410.67340584.32570-0.508803.803202.85850HepG2EIF4G2
HSPB11ENSG00000081870.7287.00160442.08250-0.623305.443704.47860HepG2HNRNPF
HSPB11ENSG00000081870.7199.75620304.79110-0.609603.041302.31050HepG2HNRNPK
HSPB11ENSG00000081870.7347.07700563.34760-0.698809.285208.11840HepG2HNRNPL
HSPB11ENSG00000081870.7333.68040511.08840-0.615104.029103.28430HepG2HNRNPLL
HSPB11ENSG00000081870.7325.30960435.32780-0.420302.523901.83160HepG2IGF2BP1
HSPB11ENSG00000081870.7216.86580305.97810-0.496602.112401.51350HepG2IGF2BP2
HSPB11ENSG00000081870.7226.29690301.05250-0.411802.378601.43230HepG2KIF1C
HSPB11ENSG00000081870.7475.09550345.511400.459403.142802.28410HepG2MSI2
HSPB11ENSG00000081870.7470.08670613.18710-0.383402.545701.81480HepG2NOL12
HSPB11ENSG00000081870.7112.17470297.55370-1.4074011.6168010.16230HepG2PABPC4
HSPB11ENSG00000081870.7352.32720621.28030-0.8183013.0791011.99160HepG2PUM1
HSPB11ENSG00000081870.7407.49270620.85410-0.607506.110805.12680HepG2PUM2
HSPB11ENSG00000081870.7232.32800393.66180-0.760803.611302.47040HepG2RBM27
HSPB11ENSG00000081870.7335.40600476.19080-0.505603.022502.31270HepG2RPLP0
HSPB11ENSG00000081870.7167.12720239.32730-0.518002.241001.68210HepG2RPS19
HSPB11ENSG00000081870.7288.93170505.88800-0.808106.763005.70160HepG2SF3B1
HSPB11ENSG00000081870.7422.16800561.12280-0.410502.904202.18650HepG2SLBP
HSPB11ENSG00000081870.7555.43280335.660300.726507.628506.93500HepG2SRSF1
HSPB11ENSG00000081870.7338.66960544.30480-0.684504.223002.95840HepG2SRSF3
HSPB11ENSG00000081870.7343.94580577.84790-0.748509.657908.58250HepG2SRSF5
HSPB11ENSG00000081870.7255.65920434.32210-0.764507.544806.48740HepG2SRSF7
HSPB11ENSG00000081870.7171.33450273.06630-0.672404.729904.04470HepG2SRSF9
HSPB11ENSG00000081870.7620.55320414.724400.581306.696005.96350HepG2SSB
HSPB11ENSG00000081870.7522.87120657.21790-0.329903.112702.46060HepG2SUCLG1
HSPB11ENSG00000081870.7330.33500498.10070-0.592504.035303.17930HepG2TARDBP
HSPB11ENSG00000081870.7265.63320377.11620-0.505603.888703.24320HepG2TRIM56
HSPB11ENSG00000081870.7449.10630571.74340-0.348302.289901.50030HepG2TUFM
HSPB11ENSG00000081870.7454.50880605.13360-0.412902.142001.41090HepG2UBE2L3
HSPB11ENSG00000081870.7226.41700374.76850-0.727006.126204.62280HepG2UTP18
HSPB11ENSG00000081870.7455.32220290.902400.646303.775002.93670HepG2XRN2
HSPB11ENSG00000081870.7270.03990400.99170-0.570405.030604.34770HepG2ZNF622
HSPB11ENSG00000081870.7918.439602014.33120-1.1330021.8903020.41820K562AQR
HSPB11ENSG00000081870.71011.255701456.31710-0.526202.878501.42990K562BUD13
HSPB11ENSG00000081870.71437.755502279.20740-0.664704.258302.89580K562CNOT7
HSPB11ENSG00000081870.71121.209601505.92750-0.425602.783701.99840K562CPSF6
HSPB11ENSG00000081870.71794.705302069.82780-0.205802.106601.52540K562DDX47
HSPB11ENSG00000081870.71847.535601580.488200.225102.106601.35390K562DKC1
HSPB11ENSG00000081870.7570.74750893.61650-0.646805.917904.54900K562EFTUD2
HSPB11ENSG00000081870.7658.44910886.46620-0.429003.505002.58440K562EIF4A3
HSPB11ENSG00000081870.7660.77910895.89380-0.439202.807901.37650K562GEMIN5
HSPB11ENSG00000081870.71136.728001437.82650-0.339002.729001.93970K562GPKOW
HSPB11ENSG00000081870.7920.992001143.61970-0.312302.508901.48530K562HNRNPA1
HSPB11ENSG00000081870.7851.561101221.52280-0.520505.667304.84330K562HNRNPC
HSPB11ENSG00000081870.71398.809701870.60320-0.419304.579203.18450K562HNRNPL
HSPB11ENSG00000081870.7916.956701227.62940-0.420902.366801.51240K562KRR1
HSPB11ENSG00000081870.71173.170701431.79030-0.287403.409902.51690K562MTPAP
HSPB11ENSG00000081870.71246.071701590.81060-0.352406.094605.04780K562NSUN2
HSPB11ENSG00000081870.7906.595501450.95550-0.678503.142002.06710K562PABPN1
HSPB11ENSG00000081870.71136.70570919.013100.306602.578101.80810K562POLR2G
HSPB11ENSG00000081870.7718.066501095.25270-0.609106.197004.76280K562PSIP1
HSPB11ENSG00000081870.71402.023801163.150200.269402.154101.55650K562PTBP1
HSPB11ENSG00000081870.72296.989202767.31990-0.268702.245601.51130K562PUF60
HSPB11ENSG00000081870.72002.400001456.622200.459004.393603.73200K562PUS1
HSPB11ENSG00000081870.71687.886601419.182400.250102.228501.68680K562RBM15
HSPB11ENSG00000081870.7774.480501115.33990-0.526205.241304.04140K562RBM22
HSPB11ENSG00000081870.7633.44170999.41850-0.657908.013606.32860K562RCC2
HSPB11ENSG00000081870.71184.619001569.77910-0.406105.502304.38030K562SF3A3
HSPB11ENSG00000081870.7865.832701162.14180-0.424604.544303.43790K562SF3B4
HSPB11ENSG00000081870.7696.87490947.40730-0.443103.464002.28260K562SRFBP1
HSPB11ENSG00000081870.71323.243901608.27750-0.281403.645902.58790K562SRPK2
HSPB11ENSG00000081870.7759.838101140.27140-0.585606.964605.85260K562SRSF1
HSPB11ENSG00000081870.7612.25490778.75170-0.347002.309401.36310K562SRSF4
HSPB11ENSG00000081870.7830.931901113.19680-0.421904.023303.00890K562TIA1
HSPB11ENSG00000081870.7761.303501053.43270-0.468603.556502.49190K562TIAL1
HSPB11ENSG00000081870.7879.878501119.29480-0.347202.583201.67560K562TRIM56
HSPB11ENSG00000081870.71385.387301686.77320-0.284003.583202.77360K562UPF1
HSPB11ENSG00000081870.71192.973501443.31380-0.274802.168701.39530K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HSPB11 is not available on ENCORE database.





19 RBPs can affect the splicing of HSPB11 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.054000.000000.00016excludedK562SF3B4
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.072000.000100.00276excludedHepG2U2AF1
SEHSPB11ENSG00000081870.7chr1-543940445439410854389205543896205439571154395818-0.339000.000000.00035excludedK562AKAP8L
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.095000.000000.00000excludedHepG2U2AF2
SEHSPB11ENSG00000081870.7chr1-543940445439410854389205543896205439571154395818-0.175000.002140.02325excludedK562AQR
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.068000.000000.00000excludedK562PUS1
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.134000.000000.00000excludedK562U2AF1
SEHSPB11ENSG00000081870.7chr1-543940445439410854389205543896205439571154395818-0.298000.000230.06449excludedK562PPIL4
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.064000.000020.00122excludedHepG2SF3A3
SEHSPB11ENSG00000081870.7chr1-5439404454394113543895765438962054395711543958180.051000.000000.00435includedK562FXR2
SEHSPB11ENSG00000081870.7chr1-543957115439581854389576543896205440565754405770-0.054000.000020.00162excludedK562UTP18
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.151000.000000.00000excludedK562U2AF2
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.053000.000150.00839excludedK562TARDBP
SEHSPB11ENSG00000081870.7chr1-543940445439411354389576543896205439571154395818-0.062000.000000.00000excludedK562RBM15
SEHSPB11ENSG00000081870.7chr1-543940445439410854389205543896205439571154395818-0.249000.000490.01582excludedK562AGGF1
A5SSHSPB11ENSG00000081870.7chr1-543957115439581854395748543958185439404454394113-0.055000.000050.00434shorterK562SRSF1
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054389576543896205441122754411602-0.113000.000000.000002includedHepG2U2AF1
MXEHSPB11ENSG00000081870.7chr1-54395711543958185440565754405770543940445439411354411227544116020.099000.007500.083571includedK562U2AF1
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054389576543896205441122754411602-0.068000.000000.000002includedK562U2AF1
MXEHSPB11ENSG00000081870.7chr1-54395711543958185440565754405770543940445439411354411227544116020.087000.003150.084121includedK562LIN28B
MXEHSPB11ENSG00000081870.7chr1-54394044543941135439571154395818543895765438962054405657544057700.105000.000260.005481includedK562U2AF2
MXEHSPB11ENSG00000081870.7chr1-54395711543958185440565754405770543940445439411354411227544116020.096000.001830.025731includedK562U2AF2
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054389576543896205441122754411602-0.086000.000000.000002includedK562U2AF2
MXEHSPB11ENSG00000081870.7chr1-54394044543941135439571154395818543895765438962054405657544057700.112000.000000.000011includedHepG2U2AF2
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054389576543896205441122754411602-0.331000.000000.000002includedHepG2U2AF2
MXEHSPB11ENSG00000081870.7chr1-5439404454394113543957115439581854389576543896205440565754405770-0.111000.000080.016232includedK562AARS
MXEHSPB11ENSG00000081870.7chr1-54394044543941135439571154395818543895765438962054405657544057700.102000.000010.001591includedK562SBDS
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054394044543941135441122754411602-0.155000.000000.000032includedK562PPIL4
MXEHSPB11ENSG00000081870.7chr1-5439404454394113543957115439581854389576543896205440565754405770-0.145000.000010.001352includedK562DDX55
MXEHSPB11ENSG00000081870.7chr1-5439571154395818544056575440577054389576543896205441122754411602-0.084000.000000.000132includedK562HNRNPK
MXEHSPB11ENSG00000081870.7chr1-54395711543958185440565754405770543895765438962054411227544116020.155000.000000.000001includedK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HSPB11 is not avaliable on ENCORE database.