HDHD2

General Information

Gene Name       : HDHD2
Gene ID             : ENSG00000167220.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HDHD2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HDHD2ENSG00000167220.1114.7313.8314.28ENCSR000AEF
HepG2HDHD2ENSG00000167220.1128.0530.1829.12ENCSR985KAT
K562HDHD2ENSG00000167220.1115.9016.9316.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HDHD2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • HDHD2 RNA is bound by 15 proteins.  







eCLIP assay for HDHD2 is not avaliable on ENCORE database.





15 proteins are bound to HDHD2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr184466086944660984-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.559785.55970K562YBX3
chr184463471444634795-3'-UTR,intron-Distal,intron-Proximal3.963625.61622K562UPF1
chr184464158644641677-3'-UTR,CDS,intron-Distal,intron-Proximal4.543666.51488K562LIN28B
chr184466273744662822-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.047196.42503K562DDX3X
chr184463457044634664-3'-UTR,intron-Distal,intron-Proximal3.306217.65451K562UPF1
chr184466086644660958-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.705183.86355HepG2PPIG
chr184466086444660968-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.533786.60490HepG2BCLAF1
chr184467679144676851-5'-UTR,intron-Distal,intron-Proximal3.506204.52274HepG2NCBP2
chr184467666244676795-5'-UTR,intron-Distal,intron-Proximal3.665286.02304HepG2GRWD1
chr184467674844676796-5'-UTR,intron-Distal4.295356.02664K562DDX3X
chr184467665544676790-5'-UTR,intron-Distal,intron-Proximal3.224396.30560HepG2SRSF1
chr184467679644676845-5'-UTR,intron-Distal,intron-Proximal5.121144.97000K562DDX3X
chr184466273444662803-3'-UTR,CDS,intron-Distal4.930565.68196HepG2BCLAF1
chr184467303044673111-intron-Distal3.185105.01170K562KHSRP
chr184467269144672739-intron-Distal3.658265.54651HepG2SUGP2
chr184467273944672781-intron-Distal3.450314.57452HepG2SUGP2
chr184467218444672236-intron-Distal3.823865.61842HepG2MATR3
chr184467269744672731-intron-Distal3.103713.77382HepG2HNRNPM
chr184467300244673101-intron-Distal3.181093.10946HepG2SFPQ
chr184467165744671701-intron-Distal4.030843.27946HepG2HNRNPM
chr184467150044671539-intron-Distal4.351264.31720HepG2MATR3
chr184467091444670967-intron-Distal3.393326.01170HepG2MATR3
chr184466521744665312-intron-Distal4.505214.85626K562TARDBP
chr184467236044672401-intron-Distal4.618186.36848HepG2SUGP2
chr184467106544671118-intron-Distal3.081064.89395HepG2SUGP2
chr184467311144673207-intron-Distal3.600914.13620K562KHSRP
chr184467548244675685-intron-Distal,intron-Proximal3.473428.66097K562KHSRP
chr184467166844671701-intron-Distal3.427414.14346HepG2SUGP2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HDHD2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HDHD2 is not available on ENCORE database.

  • 66 RBPs can affect the levels of HDHD2.  








The Knockdown/knockout RNA-Seq assay for HDHD2 is not available on ENCORE database.





66 RBPs can affect the gene expression of HDHD2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HDHD2ENSG00000167220.71151.64650897.873300.359001.987601.52750HepG2AKAP1
HDHD2ENSG00000167220.71117.52610742.912000.588905.292504.22340HepG2ASCC1
HDHD2ENSG00000167220.7617.91030897.34810-0.538307.478606.44000HepG2AUH
HDHD2ENSG00000167220.7378.23140534.02600-0.497602.184601.35470HepG2BCCIP
HDHD2ENSG00000167220.7884.71770490.723100.850204.514403.53420HepG2CNOT7
HDHD2ENSG00000167220.7630.16160421.333800.580703.327701.79010HepG2CSTF2T
HDHD2ENSG00000167220.7327.16130783.67980-1.2603026.6012025.02800HepG2CELF1
HDHD2ENSG00000167220.7674.75810842.79770-0.320803.588302.76380HepG2DAZAP1
HDHD2ENSG00000167220.71079.01800860.088700.327101.882301.35610HepG2DDX3X
HDHD2ENSG00000167220.7312.49040738.84800-1.2415014.1014012.84340HepG2DDX6
HDHD2ENSG00000167220.7450.93370710.25860-0.655405.307804.50340HepG2EIF2S1
HDHD2ENSG00000167220.7535.65000796.39640-0.572205.196604.10040HepG2EIF4G2
HDHD2ENSG00000167220.71257.055401030.307700.286902.733002.13550HepG2ETF1
HDHD2ENSG00000167220.7360.76860542.57450-0.588704.847903.74810HepG2EWSR1
HDHD2ENSG00000167220.7313.81260483.71290-0.624204.745903.73180HepG2FUBP3
HDHD2ENSG00000167220.7356.02960569.34220-0.677303.650802.37070HepG2FUS
HDHD2ENSG00000167220.7436.25520703.70400-0.689803.352302.65200HepG2GPKOW
HDHD2ENSG00000167220.7276.08750404.88090-0.552402.829101.41140HepG2HNRNPAB
HDHD2ENSG00000167220.7469.43200618.15040-0.397002.854702.11920HepG2IGF2BP1
HDHD2ENSG00000167220.7578.74110746.75410-0.367702.105301.50730HepG2IGF2BP2
HDHD2ENSG00000167220.7447.72880552.66010-0.303802.526401.82200HepG2ILF2
HDHD2ENSG00000167220.7388.37860547.33760-0.495002.906401.66100HepG2LIN28B
HDHD2ENSG00000167220.7452.93000796.67160-0.814707.150106.17060HepG2MATR3
HDHD2ENSG00000167220.7337.40150524.91150-0.637605.034103.96770HepG2MSI2
HDHD2ENSG00000167220.7199.57870448.40200-1.167807.519906.00580HepG2PABPC1
HDHD2ENSG00000167220.7219.21230730.44620-1.7364036.6748034.90010HepG2PCBP1
HDHD2ENSG00000167220.7637.15450797.71540-0.324202.329301.77580HepG2PUF60
HDHD2ENSG00000167220.7658.57390846.17320-0.361603.132002.41890HepG2PUM2
HDHD2ENSG00000167220.7749.31420565.560600.405804.222003.48920HepG2PUS1
HDHD2ENSG00000167220.7974.50720804.909100.275702.165601.60120HepG2QKI
HDHD2ENSG00000167220.7354.53680861.13990-1.2803026.4473025.17440HepG2RBM22
HDHD2ENSG00000167220.7621.42210827.18790-0.412603.763903.15150HepG2NELFE
HDHD2ENSG00000167220.7275.43600400.79970-0.541202.307201.58210HepG2RRP9
HDHD2ENSG00000167220.7616.79850764.78490-0.310303.078202.34350HepG2SLBP
HDHD2ENSG00000167220.7432.11140992.60060-1.199803.512102.00000HepG2SNRNP200
HDHD2ENSG00000167220.71454.14300739.631300.975203.744802.83040HepG2SNRNP70
HDHD2ENSG00000167220.71364.54860807.703700.7564016.7016015.74710HepG2SRSF1
HDHD2ENSG00000167220.7479.61780844.43860-0.8161014.6411013.64900HepG2SSB
HDHD2ENSG00000167220.7892.99230522.702400.772607.307306.29200HepG2SUPV3L1
HDHD2ENSG00000167220.7914.51880726.103800.332703.131502.54020HepG2TAF15
HDHD2ENSG00000167220.7760.38790525.803200.532105.412104.76020HepG2TIAL1
HDHD2ENSG00000167220.7630.27320824.77670-0.388002.255601.50440HepG2UBE2L3
HDHD2ENSG00000167220.7707.80250514.453100.460205.143204.27590HepG2ZC3H8
HDHD2ENSG00000167220.7468.21120597.35510-0.351402.816802.26660HepG2ZNF622
HDHD2ENSG00000167220.71502.834401273.666900.238602.443601.90500K562AGGF1
HDHD2ENSG00000167220.7739.593801176.57950-0.669807.301306.42140K562AQR
HDHD2ENSG00000167220.7558.90520703.29400-0.331502.784301.82100K562BCLAF1
HDHD2ENSG00000167220.7985.572701453.42900-0.560403.031801.91300K562CNOT7
HDHD2ENSG00000167220.7415.33550533.55330-0.361402.330101.37540K562CSTF2
HDHD2ENSG00000167220.71410.591701800.59590-0.352203.586702.47440K562CELF1
HDHD2ENSG00000167220.71307.624301075.849600.281402.418601.80400K562DDX47
HDHD2ENSG00000167220.7275.01190584.50640-1.0877012.5662010.45480K562EFTUD2
HDHD2ENSG00000167220.7488.09320704.53530-0.529504.361903.33270K562EIF4A3
HDHD2ENSG00000167220.71021.17920785.518400.378402.842701.98200K562FIP1L1
HDHD2ENSG00000167220.7511.00100732.69110-0.519905.321004.51970K562FXR1
HDHD2ENSG00000167220.7431.29530687.27500-0.672203.573502.67560K562GPKOW
HDHD2ENSG00000167220.7743.551101054.93940-0.504705.055104.03270K562GRSF1
HDHD2ENSG00000167220.7720.94610898.58850-0.317802.678801.80020K562HNRNPU
HDHD2ENSG00000167220.71370.815101065.017600.364102.731001.94070K562HSPD1
HDHD2ENSG00000167220.71713.761701406.485000.285002.157001.43920K562KIF1C
HDHD2ENSG00000167220.7734.397701004.82900-0.452303.310402.38420K562MAGOH
HDHD2ENSG00000167220.7733.759101002.85790-0.450703.807902.71100K562MATR3
HDHD2ENSG00000167220.71231.594501560.99960-0.341902.420101.36660K562MSI2
HDHD2ENSG00000167220.7592.65520808.53590-0.448104.844503.79710K562MTPAP
HDHD2ENSG00000167220.7680.47750982.00830-0.529205.434403.48360K562PCBP1
HDHD2ENSG00000167220.7504.63580894.12990-0.8252010.012908.10380K562PCBP2
HDHD2ENSG00000167220.7314.88490568.79300-0.853107.600106.35260K562PRPF8
HDHD2ENSG00000167220.7698.24700976.22120-0.483504.821103.96690K562PTBP1
HDHD2ENSG00000167220.7988.679601597.86500-0.692609.195407.69220K562PUF60
HDHD2ENSG00000167220.7642.07240936.32170-0.544305.107403.92530K562RBM22
HDHD2ENSG00000167220.7649.82300886.46410-0.448004.607703.57820K562SF3A3
HDHD2ENSG00000167220.7496.73860816.82930-0.717509.389507.76720K562SF3B4
HDHD2ENSG00000167220.71341.786601030.672500.380502.891801.49910K562SSRP1
HDHD2ENSG00000167220.7437.83420968.62580-1.1456014.6397012.75780K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HDHD2 is not available on ENCORE database.





8 RBPs can affect the splicing of HDHD2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHDHD2ENSG00000167220.7chr18-446636054466366744662709446628204467674844676847-0.188000.001060.02204excludedK562SRSF1
SEHDHD2ENSG00000167220.7chr18-446566144465669944641502446417194467674844676871-0.129000.000460.00732excludedHepG2U2AF2
SEHDHD2ENSG00000167220.7chr18-4466360544663667446627094466282044676748446768470.375000.000000.00078includedHepG2DDX6
SEHDHD2ENSG00000167220.7chr18-4467541944675479446627094466282044676748446768500.258000.000150.04065includedK562SBDS
SEHDHD2ENSG00000167220.7chr18-446566144465669944641502446417194466086644661075-0.114000.004290.09374excludedHepG2SF3A3
SEHDHD2ENSG00000167220.7chr18-4466360544663667446627094466282044676748446768470.332000.000590.06151includedHepG2TAF15
A5SSHDHD2ENSG00000167220.7chr18-4466267244662820446627094466282044660866446610750.255000.001120.09473longerK562EFTUD2
A5SSHDHD2ENSG00000167220.7chr18-4466267244662820446627094466282044660866446610750.276000.000050.02989longerHepG2SSB

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HDHD2 is not avaliable on ENCORE database.