GBA2

General Information

Gene Name       : GBA2
Gene ID             : ENSG00000070610.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GBA2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GBA2ENSG00000070610.1422.7922.4922.64ENCSR000AEF
HepG2GBA2ENSG00000070610.1446.1038.6542.38ENCSR985KAT
K562GBA2ENSG00000070610.1427.7127.1027.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GBA2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GBA2 RNA is bound by 18 proteins.  







eCLIP assay for GBA2 is not avaliable on ENCORE database.





18 proteins are bound to GBA2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr93573706935737118-3'-UTR,intron-Distal3.382383.68753HepG2PCBP2
chr93573707535737203-3'-UTR,CDS,intron-Distal3.569564.02339HepG2PABPN1
chr93573825835738276-5'-UTR,CDS,intron-Distal,intron-Proximal5.515938.25598HepG2PPIG
chr93573823235738258-5'-UTR,CDS,intron-Distal,intron-Proximal4.097917.55042HepG2PPIG
chr93574895535749031-5'-UTR,intron-Distal,intron-Proximal3.181273.12542HepG2DDX3X
chr93573832335738370-5'-UTR,CDS,intron-Distal,intron-Proximal3.323017.63733HepG2PPIG
chr93573861735738691-5'-UTR,CDS,intron-Distal,intron-Proximal4.5229720.45033HepG2SF3A3
chr93574903135749200-5'-UTR,intron-Distal,intron-Proximal4.7608726.77804HepG2DDX3X
chr93573845635738527-5'-UTR,CDS,intron-Distal,intron-Proximal3.249339.25476HepG2PRPF8
chr93573852235738591-5'-UTR,CDS,intron-Distal,intron-Proximal3.425947.61685HepG2PPIG
chr93573839335738428-5'-UTR,intron-Distal,intron-Proximal4.132763.98315HepG2SF3B4
chr93573858335738674-5'-UTR,CDS,intron-Distal,intron-Proximal3.040158.78144HepG2EFTUD2
chr93573839135738443-5'-UTR,intron-Distal,intron-Proximal3.464704.94928HepG2EFTUD2
chr93573822635738280-5'-UTR,CDS,intron-Distal,intron-Proximal3.467926.79180HepG2U2AF2
chr93573862035738688-5'-UTR,CDS,intron-Distal,intron-Proximal3.749158.08874K562SF3B4
chr93573852735738596-5'-UTR,CDS,intron-Distal3.674034.06757K562UCHL5
chr93573823135738269-5'-UTR,CDS,intron-Distal,intron-Proximal3.220374.27261HepG2GRWD1
chr93573859635738675-5'-UTR,CDS,intron-Distal,intron-Proximal3.230723.23253K562SMNDC1
chr93573847435738514-5'-UTR,intron-Distal,intron-Proximal4.593606.67793HepG2EFTUD2
chr93574100635741061-CDS,intron-Distal4.408069.07963HepG2PPIG
chr93573875235738773-CDS,intron-Distal4.662325.56813HepG2PPIG
chr93573813035738169-CDS,intron-Distal,intron-Proximal3.171895.97392HepG2U2AF2
chr93574049035740525-CDS,intron-Distal,intron-Proximal3.414057.83009HepG2PRPF8
chr93574034135740413-CDS,intron-Distal,intron-Proximal5.9466411.43913K562SF3B4
chr93574033335740362-CDS,intron-Distal,intron-Proximal3.535266.51082HepG2PPIG
chr93574000335740091-CDS,intron-Distal4.9886212.59749HepG2PPIG
chr93574048735740557-CDS,intron-Distal,intron-Proximal4.165374.62090HepG2SRSF1
chr93574426535744296-CDS,intron-Distal,intron-Proximal4.327997.08947HepG2PRPF8
chr93574035035740418-CDS,intron-Distal,intron-Proximal6.5789522.86495HepG2SF3B4
chr93574429035744407-CDS,intron-Distal,intron-Proximal3.3783712.67119HepG2PPIG
chr93574093135741006-CDS,intron-Distal5.0427213.20429HepG2PPIG
chr93574430135744345-CDS,intron-Distal5.034629.70099HepG2GRWD1
chr93573792835737932-CDS,intron-Distal4.337623.89826HepG2BCLAF1
chr93574423635744295-CDS,intron-Distal,intron-Proximal4.132486.32052K562AQR
chr93574182935741911-CDS,intron-Distal,intron-Proximal5.556757.63570K562AQR
chr93574025735740300-CDS,intron-Distal3.583205.45876HepG2BCLAF1
chr93574032335740369-CDS,intron-Distal,intron-Proximal3.435094.95320HepG2U2AF2
chr93574456835744614-CDS,intron-Distal,intron-Proximal4.548068.11807HepG2PRPF8
chr93573804035738091-CDS,intron-Distal,intron-Proximal3.611848.66838HepG2BCLAF1
chr93574033735740364-CDS,intron-Distal,intron-Proximal3.003953.21309HepG2GRWD1
chr93574461135744629-CDS,intron-Distal,intron-Proximal3.210353.63043HepG2GRWD1
chr93574095535740999-CDS,intron-Distal4.411965.18972HepG2GRWD1
chr93574000035740049-CDS,intron-Distal4.301817.97334HepG2BCLAF1
chr93574050835740553-CDS,intron-Distal,intron-Proximal3.208135.30514HepG2BUD13
chr93574034435740414-CDS,intron-Distal,intron-Proximal4.1120912.86040HepG2SF3A3
chr93573969335739739-CDS,intron-Distal3.567476.70085HepG2PPIG
chr93573772435737758-CDS,intron-Distal,intron-Proximal3.378393.88924K562PRPF8
chr93573804735738133-CDS,intron-Distal,intron-Proximal3.338363.03634HepG2PABPN1
chr93574083635740882-CDS,intron-Distal4.530316.10117HepG2GRWD1
chr93573792135737936-CDS,intron-Distal,intron-Proximal4.678494.96634HepG2PPIG
chr93574461935744654-CDS,intron-Distal4.813734.38106HepG2PPIG
chr93574034335740418-CDS,intron-Distal,intron-Proximal3.376693.99908K562BUD13
chr93573784335737884-CDS,intron-Distal,intron-Proximal3.517716.13978HepG2PPIG
chr93574032835740422-CDS,intron-Distal,intron-Proximal4.256243.67527K562SMNDC1
chr93574078835740854-CDS,intron-Distal,intron-Proximal5.2100122.07985HepG2PRPF8
chr93573803235738097-CDS,intron-Distal,intron-Proximal4.5579611.88486HepG2PPIG
chr93574434535744407-CDS,intron-Distal,intron-Proximal3.575296.88650HepG2GRWD1
chr93574162635741677-CDS,intron-Distal,intron-Proximal3.217268.78955HepG2PRPF8
chr93574345035743534-intron-Distal3.519514.84707HepG2HNRNPK
chr93573866635738738-intron-Distal,intron-Proximal3.772784.57180HepG2AQR
chr93574424435744265-intron-Distal,intron-Proximal3.090323.35372HepG2PRPF8
chr93574428635744294-intron-Distal,intron-Proximal3.620295.70176HepG2AQR
chr93573863235738716-intron-Distal,intron-Proximal4.808218.87128HepG2SF3B4
chr93574107535741110-intron-Distal,intron-Proximal4.501244.82767HepG2SF3B4
chr93573925835739296-intron-Distal,intron-Proximal3.972744.75655HepG2PRPF8
chr93574425535744286-intron-Distal,intron-Proximal5.332277.81134HepG2AQR
chr93574158935741641-intron-Distal,intron-Proximal4.598618.18302HepG2RBM22
chr93574043935740511-intron-Distal,intron-Proximal5.856637.41664HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GBA2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GBA2 is not available on ENCORE database.

  • 59 RBPs can affect the levels of GBA2.  








The Knockdown/knockout RNA-Seq assay for GBA2 is not available on ENCORE database.





59 RBPs can affect the gene expression of GBA2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GBA2ENSG00000070610.101089.908301974.80570-0.8575010.033909.08750HepG2AKAP1
GBA2ENSG00000070610.10862.961901633.95530-0.9210012.9640011.37090HepG2ASCC1
GBA2ENSG00000070610.102343.535601959.003300.258503.475602.72170HepG2AUH
GBA2ENSG00000070610.101249.06140802.202000.638707.376906.45580HepG2BOP1
GBA2ENSG00000070610.101772.962601480.318700.260203.599502.85840HepG2CKAP4
GBA2ENSG00000070610.102257.914901691.848800.416301.940501.30500HepG2CNOT7
GBA2ENSG00000070610.102120.762701695.754400.322604.700303.90240HepG2CELF1
GBA2ENSG00000070610.102466.006801823.045600.4357011.249209.91520HepG2DAZAP1
GBA2ENSG00000070610.102359.424901891.648700.318702.210101.64490HepG2DDX3X
GBA2ENSG00000070610.102351.803601841.197100.353003.177101.79390HepG2DDX47
GBA2ENSG00000070610.101142.077601625.12020-0.508904.021403.28800HepG2DDX6
GBA2ENSG00000070610.101131.85070971.196300.220702.278001.67390HepG2DNAJC2
GBA2ENSG00000070610.102194.261501562.113800.490104.498803.75330HepG2EIF2S1
GBA2ENSG00000070610.102430.724001726.245100.493604.153303.37470HepG2EIF4A3
GBA2ENSG00000070610.102172.522501680.883700.370102.015401.42250HepG2EIF4B
GBA2ENSG00000070610.101666.139801189.058600.486604.966503.92630HepG2FUBP3
GBA2ENSG00000070610.101195.340701413.63800-0.242002.547401.60470HepG2HDGF
GBA2ENSG00000070610.101321.22850989.187600.417503.841003.09830HepG2HNRNPA1
GBA2ENSG00000070610.101359.170101100.304200.304702.196701.57120HepG2HNRNPC
GBA2ENSG00000070610.101545.896801270.296500.283203.061402.30990HepG2HNRNPF
GBA2ENSG00000070610.101414.804701660.56200-0.231102.472701.83140HepG2HNRNPL
GBA2ENSG00000070610.101248.44010796.666400.648006.666005.73550HepG2HNRNPLL
GBA2ENSG00000070610.101595.585601250.873500.351103.400302.60390HepG2IGF2BP1
GBA2ENSG00000070610.102471.696401642.363700.589606.600305.59880HepG2IGF2BP2
GBA2ENSG00000070610.101493.647401116.489700.419807.687006.52900HepG2ILF2
GBA2ENSG00000070610.10820.899101081.89110-0.398304.765603.68840HepG2PARN
GBA2ENSG00000070610.10792.705901025.96180-0.372104.074703.15520HepG2PRPF4
GBA2ENSG00000070610.101838.073801508.254000.285203.933003.22330HepG2PUS1
GBA2ENSG00000070610.102280.646801825.323700.321203.720903.01330HepG2QKI
GBA2ENSG00000070610.101183.962801627.78640-0.459305.708304.53340HepG2RBM15
GBA2ENSG00000070610.101097.737001879.92900-0.7761017.3078016.23870HepG2RBM22
GBA2ENSG00000070610.101065.620601875.70090-0.8157021.3358020.11130HepG2NELFE
GBA2ENSG00000070610.101482.283201746.98140-0.237002.516301.92510HepG2RECQL
GBA2ENSG00000070610.101663.404601368.509500.281401.943901.35920HepG2RPLP0
GBA2ENSG00000070610.101276.975601699.95920-0.412802.112701.41310HepG2RPS3A
GBA2ENSG00000070610.101348.90280973.380800.470608.092407.07640HepG2SAFB2
GBA2ENSG00000070610.101004.68740788.525300.349402.424101.76200HepG2SF3B1
GBA2ENSG00000070610.101648.564502123.30140-0.365106.409405.73280HepG2SRFBP1
GBA2ENSG00000070610.101452.714601831.55430-0.334304.823804.24330HepG2SRSF1
GBA2ENSG00000070610.101484.097401248.044900.249802.354301.70860HepG2SRSF7
GBA2ENSG00000070610.101174.540301490.07570-0.343304.642003.96150HepG2SRSF9
GBA2ENSG00000070610.102221.247101843.512100.268803.696603.12290HepG2SSB
GBA2ENSG00000070610.10817.754301129.34370-0.465703.549602.79800HepG2SUPV3L1
GBA2ENSG00000070610.101048.038501646.30060-0.6515012.0748011.03130HepG2TAF15
GBA2ENSG00000070610.10980.29530776.581700.336002.193001.53670HepG2TARDBP
GBA2ENSG00000070610.101333.544101062.021600.328403.107302.58270HepG2TIAL1
GBA2ENSG00000070610.10910.338801071.57950-0.235302.038201.54020HepG2TRIM56
GBA2ENSG00000070610.101051.355001317.36740-0.325402.265501.69120HepG2U2AF1
GBA2ENSG00000070610.101097.424901435.64600-0.387605.823704.87000HepG2UPF1
GBA2ENSG00000070610.101140.947501386.05990-0.280803.007702.38800HepG2UTP3
GBA2ENSG00000070610.101427.601301111.716900.360702.165201.51740HepG2XRN2
GBA2ENSG00000070610.101193.909001012.499600.237702.421901.78720HepG2ZC3H8
GBA2ENSG00000070610.101373.382401578.93590-0.201202.311301.79800HepG2ZNF622
GBA2ENSG00000070610.101436.237101869.12790-0.380103.516302.87070K562AQR
GBA2ENSG00000070610.101370.49310999.757600.454905.036003.57160K562DDX3X
GBA2ENSG00000070610.10922.18060660.596000.481205.307304.21990K562EIF3G
GBA2ENSG00000070610.101327.400901044.509000.345702.827701.99770K562EIF4A3
GBA2ENSG00000070610.10364.60470701.16520-0.943408.258306.90430K562G3BP2
GBA2ENSG00000070610.101666.372902110.23280-0.340703.254002.43670K562GRSF1
GBA2ENSG00000070610.101279.74170971.224800.397903.640502.96780K562HNRNPC
GBA2ENSG00000070610.101433.962501172.583600.290202.056801.35270K562PPIG
GBA2ENSG00000070610.10755.847201102.52050-0.544605.061304.04810K562PRPF8
GBA2ENSG00000070610.10709.593501003.39970-0.499802.280801.31160K562NELFE
GBA2ENSG00000070610.101245.16410986.831200.335402.053201.43770K562TARDBP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GBA2 is not available on ENCORE database.





29 RBPs can affect the splicing of GBA2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGBA2ENSG00000070610.10chr9-3574327235743323357417903574188735744293357443880.184000.000030.00516includedHepG2G3BP1
SEGBA2ENSG00000070610.10chr9-357416683574188735740821357410613574429335744409-0.156000.000230.02597excludedHepG2G3BP1
SEGBA2ENSG00000070610.10chr9-357399943574012035739624357397973574020535740359-0.118000.000350.01633excludedK562PRPF8
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.150000.000050.00212includedHepG2HNRNPK
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.142000.000330.02634includedHepG2AKAP1
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.244000.002570.08008includedK562FXR1
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.295000.000170.04993includedHepG2EFTUD2
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.374000.000000.00007includedK562HNRNPL
SEGBA2ENSG00000070610.10chr9-3574327235743323357417903574188735744293357443880.209000.000100.00371includedHepG2SRSF1
SEGBA2ENSG00000070610.10chr9-357405223574062535740205357403593574082135741061-0.085000.001710.07233excludedHepG2PCBP1
SEGBA2ENSG00000070610.10chr9-357405223574062535740205357403593574082135741053-0.127000.000190.02685excludedHepG2TAF15
SEGBA2ENSG00000070610.10chr9-3574327235743323357413163574188735744293357443880.352000.000640.02651includedK562TARDBP
SEGBA2ENSG00000070610.10chr9-357416683574188735740821357410613574429335744409-0.314000.000290.01438excludedK562TARDBP
A3SSGBA2ENSG00000070610.10chr9-3573822835738401357382283573837135738522357386290.217000.000110.06745longerHepG2SUPV3L1
A3SSGBA2ENSG00000070610.10chr9-3573822835738414357382283573837135738522357386290.164000.001170.03019longerHepG2U2AF2
A3SSGBA2ENSG00000070610.10chr9-3573899835739177357389983573910635739311357394160.076000.000090.00081longerK562AQR
A3SSGBA2ENSG00000070610.10chr9-3573852235738656357385223573862935738748357389000.077000.004460.02612longerK562AQR
A3SSGBA2ENSG00000070610.10chr9-3574166835741905357416683574188735744293357444090.209000.000780.08210longerK562RBM15
A3SSGBA2ENSG00000070610.10chr9-3573822835738414357382283573837135738522357386290.114000.000190.01956longerHepG2SF3B4
A5SSGBA2ENSG00000070610.10chr9-357387483573890035738814357389003573852235738629-0.132000.000320.08213shorterHepG2DDX3X
A5SSGBA2ENSG00000070610.10chr9-357387483573890035738814357389003573852235738629-0.202000.000020.00688shorterHepG2AKAP1
A5SSGBA2ENSG00000070610.10chr9-357387483573890035738814357389003573852235738629-0.141000.000320.09515shorterHepG2KHSRP
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.244000.000000.00018includedHepG2PCBP2
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.195000.000750.00577includedK562PUS1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.203000.010280.08758includedHepG2SF3A3
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.471000.000000.00000includedHepG2PRPF8
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.292000.000190.02298includedHepG2EFTUD2
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.333000.000020.01445includedHepG2HNRNPM
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.340000.000000.00000includedK562PRPF8
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.079000.000210.00760includedHepG2IGF2BP3
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.074000.001110.01729includedHepG2PCBP1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.071000.001620.03699includedHepG2SRSF1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.126000.000010.00013includedHepG2TAF15
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.293000.000050.00085includedHepG2U2AF1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.068000.002010.03450includedHepG2G3BP1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.206000.001540.02889includedHepG2TIAL1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.113000.000000.00008includedHepG2NCBP2
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.184000.000200.04999includedHepG2FUS
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.160000.000000.00000includedHepG2SF3B4
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.142000.000000.00012includedHepG2SRSF9
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.174000.000000.00000includedHepG2HNRNPK
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.074000.000920.02349includedHepG2PTBP1
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.400000.000000.00000includedK562EFTUD2
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.158000.000170.01012includedK562TARDBP
RIGBA2ENSG00000070610.10chr9-3573803335738266357380333573814935738228357382660.260000.000000.00002includedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GBA2 is not avaliable on ENCORE database.