FPGS

General Information

Gene Name       : FPGS
Gene ID             : ENSG00000136877.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: FPGS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FPGSENSG00000136877.1430.9255.2643.09ENCSR000AEF
HepG2FPGSENSG00000136877.1453.1327.9240.53ENCSR985KAT
K562FPGSENSG00000136877.1463.4458.1160.77ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FPGS is not avaliable on ENCORE database.



Proteins bound to RNA
  • FPGS RNA is bound by 16 proteins.  







eCLIP assay for FPGS is not avaliable on ENCORE database.





16 proteins are bound to FPGS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr9130576179130576229+3'-UTR,intron-Distal3.584283.89838K562PABPC4
chr9130576101130576176+3'-UTR,intron-Distal4.557344.99801K562PABPC4
chr9130576034130576092+3'-UTR,intron-Distal4.194917.02275K562SLBP
chr9130575965130575996+3'-UTR,intron-Distal5.091705.94584K562PABPC4
chr9130575964130576022+3'-UTR,intron-Distal5.0162410.24910HepG2SUB1
chr9130571000130571080+CDS,intron-Proximal3.770964.52919HepG2SF3B4
chr9130570851130570938+CDS,intron-Distal3.454736.93667HepG2PPIG
chr9130570872130570939+CDS,intron-Distal4.396705.01214HepG2BUD13
chr9130569942130570006+CDS,intron-Proximal3.9363612.22234HepG2PRPF8
chr9130566952130567017+CDS,intron-Distal,intron-Proximal4.0173511.87912HepG2PRPF8
chr9130566674130566723+CDS,intron-Distal,intron-Proximal4.035514.45914HepG2PRPF8
chr9130571914130571985+CDS,intron-Proximal3.460713.41960K562GTF2F1
chr9130566864130566953+CDS,intron-Distal,intron-Proximal3.100588.30811K562EFTUD2
chr9130571919130571980+CDS,intron-Proximal3.153116.67352HepG2PRPF8
chr9130572245130572318+CDS,intron-Proximal3.366854.07440K562PRPF8
chr9130566977130567065+CDS,intron-Distal,intron-Proximal3.373835.25094K562PRPF8
chr9130570520130570587+CDS3.195506.47139HepG2PPIG
chr9130566795130566832+CDS,intron-Distal,intron-Proximal3.672397.87154HepG2PPIG
chr9130566751130566798+CDS,intron-Distal,intron-Proximal5.289836.63358K562EFTUD2
chr9130569295130569366+CDS,intron-Distal3.664356.36657K562YBX3
chr9130570561130570622+CDS,intron-Proximal3.7172610.01959HepG2PRPF8
chr9130570498130570556+CDS,intron-Proximal3.318106.51847HepG2U2AF2
chr9130566913130566943+CDS,intron-Distal,intron-Proximal4.7604311.38699HepG2PPIG
chr9130571941130572004+CDS,intron-Proximal3.364115.58816K562PRPF8
chr9130569965130570008+CDS,intron-Proximal4.692756.16445HepG2PPIG
chr9130571027130571085+CDS,intron-Proximal4.143394.84268K562SF3B4
chr9130572238130572334+CDS,intron-Proximal5.0246214.79448HepG2PRPF8
chr9130566792130566832+CDS,intron-Distal,intron-Proximal5.176485.73530K562DDX24
chr9130571931130572005+CDS,intron-Proximal3.159533.90373HepG2AQR
chr9130566914130566947+CDS,intron-Distal,intron-Proximal3.220583.17151K562UCHL5
chr9130569864130569944+CDS,intron-Proximal3.534917.63733HepG2PPIG
chr9130571934130572052+CDS,intron-Proximal6.1720614.27141K562AQR
chr9130570782130570834+intron-Distal,intron-Proximal3.659638.68003HepG2SF3B4
chr9130570019130570110+intron-Distal,intron-Proximal5.352169.49243K562PRPF8
chr9130570785130570835+intron-Distal,intron-Proximal3.972874.84268K562SF3B4
chr9130571246130571299+intron-Distal,intron-Proximal4.843293.65355K562EFTUD2
chr9130569373130569429+intron-Distal,intron-Proximal4.517805.04056HepG2RBFOX2
chr9130570039130570079+intron-Distal,intron-Proximal4.393064.75425K562EFTUD2
chr9130571244130571287+intron-Distal,intron-Proximal3.888894.89208K562AQR
chr9130571251130571325+intron-Distal,intron-Proximal3.897666.00776K562PRPF8
chr9130570061130570098+intron-Distal,intron-Proximal3.929354.49024K562AQR
chr9130569441130569485+intron-Distal,intron-Proximal5.448845.58036HepG2EFTUD2
chr9130572233130572301+intron-Proximal5.292206.14086K562GTF2F1
chr9130572228130572294+intron-Proximal4.701395.89229K562EFTUD2
chr9130571028130571062+intron-Proximal5.202925.24235HepG2EFTUD2
chr9130572244130572309+intron-Proximal5.121899.24251HepG2EFTUD2
chr9130572390130572448+intron-Proximal5.030165.17615K562AQR
chr9130572203130572290+intron-Proximal5.5152310.20819HepG2FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FPGS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FPGS is not available on ENCORE database.

  • 65 RBPs can affect the levels of FPGS.  








The Knockdown/knockout RNA-Seq assay for FPGS is not available on ENCORE database.





65 RBPs can affect the gene expression of FPGS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FPGSENSG00000136877.10625.45770481.816900.376303.358902.69930HepG2ACO1
FPGSENSG00000136877.10807.11040586.033700.461702.034901.57070HepG2AKAP1
FPGSENSG00000136877.10303.06420484.84740-0.677902.715401.93770HepG2ASCC1
FPGSENSG00000136877.10274.09120385.79900-0.493202.800102.02440HepG2CALR
FPGSENSG00000136877.10364.87020491.63470-0.430203.181902.50250HepG2CELF1
FPGSENSG00000136877.10263.51150353.91610-0.425502.038701.44590HepG2DDX21
FPGSENSG00000136877.10235.96440346.69300-0.555102.699701.79930HepG2DDX24
FPGSENSG00000136877.10645.88720401.192600.686903.886602.98550HepG2DDX55
FPGSENSG00000136877.10222.87210319.44500-0.519402.797901.80880HepG2DHX30
FPGSENSG00000136877.10431.24580331.211300.380702.410701.74890HepG2DNAJC21
FPGSENSG00000136877.10267.10780412.74720-0.627804.408003.42940HepG2FUBP3
FPGSENSG00000136877.10413.93650558.89170-0.433203.549602.74530HepG2HNRNPF
FPGSENSG00000136877.10606.72240481.551000.333202.701902.03570HepG2HNRNPL
FPGSENSG00000136877.10284.61080369.47080-0.376502.378501.81330HepG2HNRNPU
FPGSENSG00000136877.10281.17440438.65270-0.641602.841201.86000HepG2MTPAP
FPGSENSG00000136877.10227.11190381.34900-0.747704.713003.74520HepG2NSUN2
FPGSENSG00000136877.10253.13250455.40610-0.847309.691808.37510HepG2PRPF4
FPGSENSG00000136877.10734.54500531.180400.467505.632904.84900HepG2PUM1
FPGSENSG00000136877.10351.62200590.65210-0.748307.845806.87550HepG2QKI
FPGSENSG00000136877.10750.20010550.918600.445303.680002.70640HepG2RBM15
FPGSENSG00000136877.10506.76960778.45050-0.619305.395604.73220HepG2RBM22
FPGSENSG00000136877.10363.59610602.02830-0.727506.514205.52920HepG2RPLP0
FPGSENSG00000136877.10515.29440383.724000.425203.687302.96280HepG2SMN1
FPGSENSG00000136877.10564.70270879.20450-0.638709.838209.05120HepG2SRFBP1
FPGSENSG00000136877.10689.58540494.056200.481004.960804.16110HepG2SRSF5
FPGSENSG00000136877.10380.34110482.18590-0.342302.280001.76880HepG2SRSF9
FPGSENSG00000136877.10638.90210763.31100-0.256702.125001.65990HepG2SSB
FPGSENSG00000136877.10732.48310561.881100.382403.641702.94660HepG2SUCLG1
FPGSENSG00000136877.10281.09450399.32410-0.506502.627001.96570HepG2SUPV3L1
FPGSENSG00000136877.10407.19410532.75460-0.387802.092401.59220HepG2TAF15
FPGSENSG00000136877.10316.75980419.23150-0.404402.024401.39240HepG2TARDBP
FPGSENSG00000136877.10291.80560550.45680-0.915608.417507.32030HepG2U2AF1
FPGSENSG00000136877.10311.24950449.43950-0.530104.656703.82280HepG2ZC3H8
FPGSENSG00000136877.101187.90750802.371700.566008.829807.89140K562AGGF1
FPGSENSG00000136877.10566.267701269.69240-1.1649019.0619017.68590K562AQR
FPGSENSG00000136877.101175.53790875.991900.424204.860003.61260K562ATP5C1
FPGSENSG00000136877.10343.92090497.30250-0.532003.311702.35590K562BOP1
FPGSENSG00000136877.10375.75620528.74730-0.492803.568102.67840K562CPSF6
FPGSENSG00000136877.101108.816501743.24880-0.6528011.008709.13480K562CELF1
FPGSENSG00000136877.10874.66150614.853000.508405.744803.61690K562DDX6
FPGSENSG00000136877.10557.78550291.844800.9344011.598809.94890K562EIF3G
FPGSENSG00000136877.10374.92260608.79650-0.699405.547203.85020K562FKBP4
FPGSENSG00000136877.10321.37310538.04200-0.743506.340705.02700K562FMR1
FPGSENSG00000136877.10304.02600456.06270-0.585003.577102.52610K562FTO
FPGSENSG00000136877.10176.21600258.01620-0.550102.917101.53660K562FUS
FPGSENSG00000136877.1048.34830244.65820-2.339207.988606.66140K562G3BP2
FPGSENSG00000136877.10430.93450701.20980-0.702407.079306.16700K562HNRNPC
FPGSENSG00000136877.10735.96170550.643200.418402.519101.63360K562HNRNPM
FPGSENSG00000136877.10770.036201301.69450-0.757404.328303.20070K562HNRNPU
FPGSENSG00000136877.101252.33340907.476200.464604.191903.21850K562HSPD1
FPGSENSG00000136877.10561.69070900.51150-0.681002.718401.30910K562ILF2
FPGSENSG00000136877.10232.95640431.09590-0.887905.715904.31620K562KRR1
FPGSENSG00000136877.10731.12240973.15390-0.412604.722403.68870K562MTPAP
FPGSENSG00000136877.10657.058701051.63230-0.678503.938302.94590K562PCBP3
FPGSENSG00000136877.10567.51860806.59940-0.507205.016603.93480K562POLR2G
FPGSENSG00000136877.101115.00070759.977000.552905.567004.33530K562PPIG
FPGSENSG00000136877.10700.70250459.568900.608402.161801.56310K562PTBP1
FPGSENSG00000136877.101206.782501546.71900-0.358002.940002.09860K562PUF60
FPGSENSG00000136877.101288.105101645.33400-0.353103.737702.48090K562PUM1
FPGSENSG00000136877.101367.962301611.94270-0.236802.277501.40490K562PUM2
FPGSENSG00000136877.101050.34580828.045200.343002.483201.96230K562PUS1
FPGSENSG00000136877.101045.48810806.757800.373903.523802.86780K562RBM15
FPGSENSG00000136877.10732.96710573.623300.353502.481401.54680K562RCC2
FPGSENSG00000136877.10973.79930718.820300.437902.843801.74630K562SAFB
FPGSENSG00000136877.10287.23770480.16540-0.741304.922803.59910K562SF3B1
FPGSENSG00000136877.10820.88450543.778800.594105.508103.91610K562SRFBP1
FPGSENSG00000136877.10493.13640869.81090-0.818703.030101.51770K562SUPT6H
FPGSENSG00000136877.10121.29440236.80080-0.965202.438201.42340K562U2AF1
FPGSENSG00000136877.1092.44150244.67900-1.404306.071104.88590K562U2AF2
FPGSENSG00000136877.10932.637801146.48600-0.297803.190402.42180K562UPF1
FPGSENSG00000136877.10793.20450981.01200-0.306602.255801.46630K562WDR3
FPGSENSG00000136877.10606.712401020.13730-0.7497015.3271013.55070K562WDR43
FPGSENSG00000136877.101115.607601430.42350-0.358603.124302.20050K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FPGS is not available on ENCORE database.





12 RBPs can affect the splicing of FPGS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFPGSENSG00000136877.10chr9+130570836130570984130570512130570590130571078130571161-0.122000.004760.04463excludedK562AQR
SEFPGSENSG00000136877.10chr9+130569487130569565130569251130569366130569699130569761-0.076000.000540.01148excludedK562HNRNPC
A3SSFPGSENSG00000136877.10chr9+130569251130569366130569270130569366130566914130566979-0.175000.000000.00020shorterK562EFTUD2
A3SSFPGSENSG00000136877.10chr9+130569251130569366130569270130569366130566914130566979-0.131000.000040.00991shorterK562PRPF8
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.109000.001700.05969longerK562PUS1
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.161000.000000.00005longerK562AQR
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.613000.000030.00190longerHepG2U2AF2
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.155000.000020.00925longerHepG2NCBP2
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.303000.000250.04019longerHepG2TIAL1
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.124000.000020.00365longerK562EFTUD2
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.323000.000010.00101longerK562U2AF2
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.169000.000000.00000longerK562HNRNPU
A5SSFPGSENSG00000136877.10chr9+1305698641305700541305698641305699671305705121305705900.362000.000280.02937longerHepG2U2AF1
RIFPGSENSG00000136877.10chr9+1305665931305668311305665931305666921305667771305668310.074000.000010.00008includedK562AQR
MXEFPGSENSG00000136877.10chr9+130569251130569366130569487130569565130566914130566979130569699130569761-0.115000.000910.052682includedK562LARP7
MXEFPGSENSG00000136877.10chr9+130566914130566979130569270130569366130566777130566831130569487130569565-0.156000.004550.044712includedHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FPGS is not avaliable on ENCORE database.