FBXO18

General Information

Gene Name       : FBXO18
Gene ID             :
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FBXO18)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FBXO18 is not avaliable on ENCORE database.



Proteins bound to RNA
  • FBXO18 RNA is bound by 40 proteins.  







eCLIP assay for FBXO18 is not avaliable on ENCORE database.





40 proteins are bound to FBXO18 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1059561995956271+3'-UTR,CDS,intron-Proximal3.591497.09156HepG2PRPF8
chr1059792405979403+3'-UTR3.850505.82560HepG2PABPN1
chr1059574845957494+3'-UTR,CDS4.867077.83423K562YBX3
chr1059574945957516+3'-UTR,CDS3.867149.76876K562YBX3
chr1059793305979470+3'-UTR4.1437710.31453K562PABPC4
chr1059574415957512+3'-UTR,CDS3.897863.19682HepG2PABPN1
chr1059508875950961+5'-UTR,CDS,intron-Proximal3.212794.37145K562GRWD1
chr1059508885950963+5'-UTR,CDS4.662776.50203HepG2GRWD1
chr1059530895953143+5'-UTR,CDS,intron-Proximal3.438585.56310HepG2PRPF8
chr1059449825944995+5'-UTR,CDS,intron-Distal,intron-Proximal3.506733.70637K562DDX3X
chr1059449955945114+5'-UTR,CDS,intron-Distal4.6642216.40314K562DDX3X
chr1059530905953125+5'-UTR,CDS,intron-Proximal3.573868.23725K562AQR
chr1059479545948007+5'-UTR,CDS,intron-Proximal4.392347.15298K562AQR
chr1059479835948060+5'-UTR,CDS,intron-Proximal3.952994.07833HepG2U2AF1
chr1059508995951002+5'-UTR,CDS3.318786.02234K562UCHL5
chr1059509595951016+5'-UTR,CDS5.591039.44903HepG2PPIG
chr1059322105932331+5'-UTR,CDS,intron-Distal,intron-Proximal3.313476.49144HepG2SRSF1
chr1059322995932356+5'-UTR,CDS,intron-Distal,intron-Proximal3.402584.54206HepG2PRPF8
chr1059321995932333+5'-UTR,CDS,intron-Distal,intron-Proximal3.920269.71466HepG2NCBP2
chr1059512555951304+5'-UTR,CDS,intron-Proximal4.4630913.26139HepG2PRPF8
chr1059322195932315+5'-UTR,CDS,intron-Distal,intron-Proximal5.0235812.62211K562DDX3X
chr1059322405932305+5'-UTR,intron-Distal3.912328.75653HepG2DDX3X
chr1059528515952920+5'-UTR,CDS,intron-Proximal3.789868.78792K562BUD13
chr1059479705948019+5'-UTR,CDS,intron-Proximal3.575905.55543K562GPKOW
chr1059484585948521+5'-UTR,CDS3.586343.93112K562RBM15
chr1059322215932306+5'-UTR,intron-Distal4.034063.39325K562SRSF1
chr1059451145945169+5'-UTR,CDS,intron-Distal,intron-Proximal4.620477.46483HepG2PRPF8
chr1059512345951300+5'-UTR,CDS,intron-Proximal3.233434.63145K562BUD13
chr1059479635948015+5'-UTR,CDS,intron-Proximal3.471856.11414K562BUD13
chr1059485485948596+5'-UTR,CDS,intron-Proximal3.789117.65528K562ZNF622
chr1059511335951254+5'-UTR,CDS3.684964.44179K562METAP2
chr1059509635951013+5'-UTR,CDS4.097814.01763HepG2GRWD1
chr1059508875950959+5'-UTR,CDS,intron-Proximal3.551127.64107HepG2PPIG
chr1059511255951251+5'-UTR,CDS5.463407.22868K562FXR2
chr1059528515952924+5'-UTR,CDS,intron-Proximal5.1607022.38149K562AQR
chr1059582075958296+CDS3.188887.86167K562YBX3
chr1059784575978544+CDS3.685666.00726K562YBX3
chr1059634835963541+CDS,intron-Proximal4.780034.68690HepG2PRPF8
chr1059672825967368+CDS,intron-Proximal4.465979.71879K562SF3B4
chr1059594535959507+CDS,intron-Proximal3.996516.65114HepG2PRPF8
chr1059785485978600+CDS,intron-Proximal4.060864.49024K562AQR
chr1059655925965709+CDS,intron-Proximal3.419804.80471K562GRWD1
chr1059604405960459+CDS,intron-Proximal4.247596.01372K562AQR
chr1059784185978462+CDS,intron-Proximal4.698864.78529HepG2BCLAF1
chr1059635115963593+CDS,intron-Proximal4.345848.17582K562PRPF8
chr1059582165958278+CDS4.530755.52476K562BUD13
chr1059664175966463+CDS3.698863.68471HepG2BCLAF1
chr1059784205978453+CDS4.267183.79199HepG2PPIG
chr1059595825959638+CDS4.033764.23295HepG2GRWD1
chr1059656105965663+CDS,intron-Proximal3.554105.97823HepG2BCLAF1
chr1059634175963478+CDS4.688315.50697K562UCHL5
chr1059664445966507+CDS,intron-Proximal4.520949.27995K562PRPF8
chr1059593925959430+CDS3.962483.44423K562BUD13
chr1059673285967353+CDS,intron-Proximal4.554935.27053HepG2PPIG
chr1059694325969467+CDS3.406383.68471HepG2BCLAF1
chr1059664535966520+CDS,intron-Proximal4.9193010.85246HepG2PRPF8
chr1059575165957525+CDS3.386798.47737K562YBX3
chr1059595945959642+CDS,intron-Proximal3.270704.68592HepG2PPIG
chr1059694885969505+CDS,intron-Proximal4.498593.89826HepG2BCLAF1
chr1059634685963524+CDS3.296994.05781K562DDX24
chr1059663085966384+CDS4.238704.69889HepG2GRWD1
chr1059694935969539+CDS,intron-Proximal4.405174.22101K562PRPF8
chr1059672895967364+CDS,intron-Proximal3.473348.66286K562BUD13
chr1059583125958400+CDS3.557214.53005K562YBX3
chr1059634615963520+CDS3.581603.66187K562ZNF622
chr1059673995967453+CDS3.198863.17233HepG2BCLAF1
chr1059347555934849+intron-Distal3.239215.50064HepG2PTBP1
chr1059342885934340+intron-Distal4.872604.31871HepG2HNRNPM
chr1059360705936125+intron-Distal3.725245.30446HepG2SUGP2
chr1059548205954905+intron-Distal3.805263.66668K562KHSRP
chr1059330955933155+intron-Distal,intron-Proximal3.459993.83677K562HNRNPM
chr1059328225932877+intron-Distal3.462813.64140HepG2SFPQ
chr1059323915932457+intron-Distal,intron-Proximal3.824164.72700HepG2GTF2F1
chr1059323915932480+intron-Distal,intron-Proximal3.5939110.54509HepG2CSTF2T
chr1059549265955059+intron-Distal3.880345.63625HepG2HNRNPM
chr1059549055955004+intron-Distal3.001243.48890K562KHSRP
chr1059324765932571+intron-Distal4.366369.93975HepG2PRPF4
chr1059448525944959+intron-Distal,intron-Proximal3.229263.61506K562NONO
chr1059325845932647+intron-Distal3.093706.22729HepG2CSTF2T
chr1059331045933145+intron-Distal,intron-Proximal5.145376.08412HepG2HNRNPM
chr1059325605932645+intron-Distal3.664385.37976K562NONO
chr1059327795932885+intron-Distal,intron-Proximal3.702165.16186K562NONO
chr1059331105933150+intron-Distal,intron-Proximal3.361873.84025HepG2SUGP2
chr1059353875935469+intron-Distal3.737444.36087HepG2MATR3
chr1059356935935820+intron-Distal4.270356.74598HepG2QKI
chr1059356205935763+intron-Distal3.862658.76201K562RBFOX2
chr1059675325967580+intron-Distal,intron-Proximal3.879233.60944K562TARDBP
chr1059325315932581+intron-Distal4.022753.53404K562HNRNPM
chr1059324805932584+intron-Distal3.8396311.96916HepG2CSTF2T
chr1059347655934831+intron-Distal3.222783.09339K562MATR3
chr1059478485947907+intron-Distal,intron-Proximal3.272074.52210K562KHSRP
chr1059340665934171+intron-Distal3.873095.80877K562EXOSC5
chr1059323615932514+intron-Distal,intron-Proximal3.777816.38596HepG2GRSF1
chr1059587615958840+intron-Distal4.320399.70575K562EFTUD2
chr1059360135936069+intron-Distal4.882826.61547K562HNRNPM
chr1059341375934194+intron-Distal3.383963.63437HepG2HNRNPM
chr1059424615942514+intron-Distal3.195353.19398HepG2XPO5
chr1059327565932799+intron-Distal3.053213.15890HepG2GTF2F1
chr1059356835935752+intron-Distal3.553547.03905HepG2SUGP2
chr1059360705936126+intron-Distal3.896196.58367HepG2HNRNPM
chr1059382015938251+intron-Distal3.994744.10323HepG2PRPF4
chr1059341085934193+intron-Distal4.9657514.45079HepG2SUGP2
chr1059323975932479+intron-Distal,intron-Proximal3.935907.50007K562GTF2F1
chr1059324415932598+intron-Distal3.151555.01255K562XRN2
chr1059786135978661+intron-Distal,intron-Proximal4.699634.65563K562AQR
chr1059586895958761+intron-Distal6.5556212.75970K562EFTUD2
chr1059327455932829+intron-Distal3.311475.36345K562EWSR1
chr1059344325934505+intron-Distal3.777897.98957HepG2SUGP2
chr1059343545934390+intron-Distal4.301124.38558HepG2HNRNPM
chr1059324955932588+intron-Distal5.135146.81276K562GTF2F1
chr1059587325958793+intron-Distal3.337076.89918K562PRPF8
chr1059346165934656+intron-Distal4.884077.14375HepG2SUGP2
chr1059341085934188+intron-Distal5.007737.91259HepG2MATR3
chr1059512765951435+intron-Distal,intron-Proximal3.088783.73266K562KHSRP
chr1059342395934288+intron-Distal4.140037.32988HepG2HNRNPM
chr1059355715935629+intron-Distal4.289863.42734K562PTBP1
chr1059323815932483+intron-Distal,intron-Proximal3.907967.11359K562CSTF2T
chr1059360695936155+intron-Distal4.414899.28343K562HNRNPM
chr1059343805934432+intron-Distal3.379308.99518HepG2SUGP2
chr1059323825932480+intron-Distal,intron-Proximal3.753824.49762HepG2XRN2
chr1059340355934105+intron-Distal3.345934.08043K562HNRNPM
chr1059340185934161+intron-Distal3.009453.52648K562NONO
chr1059323745932476+intron-Distal,intron-Proximal3.083187.73353HepG2PRPF4
chr1059356885935731+intron-Distal4.443838.70378HepG2HNRNPM
chr1059479275947999+intron-Proximal5.230165.40008K562SF3B4
chr1059558045955865+intron-Proximal4.204125.97994K562AQR
chr1059531255953137+intron-Proximal3.895798.13013K562AQR
chr1059558185955889+intron-Proximal3.660704.58287K562PRPF8
chr1059575405957577+intron-Proximal4.527314.13847K562AQR
chr1059512855951313+intron-Proximal5.7845919.62251K562AQR
chr1059512595951285+intron-Proximal4.9974314.41880K562AQR
chr1059695215969546+intron-Proximal3.942344.15711K562AQR
chr1059604595960484+intron-Proximal4.395796.39176K562AQR
chr1059512575951259+intron-Proximal4.8240112.86643K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FBXO18 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FBXO18 is not available on ENCORE database.

  • 39 RBPs can affect the levels of FBXO18.  








The Knockdown/knockout RNA-Seq assay for FBXO18 is not available on ENCORE database.





39 RBPs can affect the gene expression of FBXO18 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FBXO18ENSG00000134452.151457.491601256.954700.213502.196001.64110HepG2ACO1
FBXO18ENSG00000134452.151997.844801605.902700.315001.820301.37920HepG2AKAP1
FBXO18ENSG00000134452.151410.438201141.936100.304602.214501.67370HepG2BOP1
FBXO18ENSG00000134452.15706.258701048.35170-0.569905.314804.39080HepG2CPSF6
FBXO18ENSG00000134452.15998.022101202.55630-0.269002.606001.94670HepG2DKC1
FBXO18ENSG00000134452.15639.96130925.35200-0.532005.236703.97340HepG2HNRNPM
FBXO18ENSG00000134452.15884.222601042.97440-0.238202.062501.52980HepG2HNRNPU
FBXO18ENSG00000134452.151284.033001065.363900.269203.333802.53510HepG2ILF2
FBXO18ENSG00000134452.151151.443501458.47920-0.341002.178401.61440HepG2NCBP2
FBXO18ENSG00000134452.151029.961701298.69680-0.334502.102701.46480HepG2PABPC4
FBXO18ENSG00000134452.151156.247801340.15450-0.212901.830201.36760HepG2PTBP1
FBXO18ENSG00000134452.15978.254901280.28490-0.388205.596204.77580HepG2PUS1
FBXO18ENSG00000134452.15959.036701317.19990-0.457804.691303.83420HepG2RBM25
FBXO18ENSG00000134452.151166.188801491.42110-0.354904.217103.57460HepG2NELFE
FBXO18ENSG00000134452.15946.31580745.274500.344402.572901.97860HepG2RPS19
FBXO18ENSG00000134452.151653.641801920.96280-0.216202.503002.01800HepG2SRFBP1
FBXO18ENSG00000134452.151028.007801456.30590-0.502508.134007.42210HepG2SRSF1
FBXO18ENSG00000134452.15791.667801309.08770-0.7256012.8589011.78380HepG2TAF15
FBXO18ENSG00000134452.15768.535101154.69820-0.587303.848502.59720HepG2XRCC6
FBXO18ENSG00000134452.15760.057101002.47950-0.399405.097204.23300HepG2ZC3H8
FBXO18ENSG00000134452.151833.794702215.26610-0.272603.569502.93910K562AGGF1
FBXO18ENSG00000134452.152673.277803334.94450-0.319102.942702.34010K562AQR
FBXO18ENSG00000134452.153703.233002928.625600.338506.136005.21900K562DDX47
FBXO18ENSG00000134452.151165.676001661.28100-0.511105.207503.93430K562EFTUD2
FBXO18ENSG00000134452.152191.313602589.17430-0.240702.706901.99400K562EIF2S2
FBXO18ENSG00000134452.151620.222001276.097800.344404.068003.11290K562EIF3G
FBXO18ENSG00000134452.152391.849601620.175200.5619011.4766010.33020K562FXR1
FBXO18ENSG00000134452.15803.700401157.84250-0.526703.542902.72080K562G3BP2
FBXO18ENSG00000134452.151627.373801950.13780-0.261002.101601.57230K562HNRNPC
FBXO18ENSG00000134452.151158.786301789.34610-0.626806.313904.82380K562HNRNPM
FBXO18ENSG00000134452.152236.786802588.36770-0.210603.569202.73220K562NSUN2
FBXO18ENSG00000134452.151391.636401748.51220-0.329302.850101.92940K562PSIP1
FBXO18ENSG00000134452.152262.434101825.323900.309603.050702.35700K562PTBP1
FBXO18ENSG00000134452.153825.674604594.58440-0.264203.354002.29570K562PUM2
FBXO18ENSG00000134452.151897.646202286.10290-0.268701.941101.47110K562PUS1
FBXO18ENSG00000134452.151785.710602227.37500-0.318803.749603.07480K562RBM15
FBXO18ENSG00000134452.15725.154701097.97300-0.598507.050604.81850K562RBM25
FBXO18ENSG00000134452.151456.85490909.727000.679307.341205.61190K562RPS3
FBXO18ENSG00000134452.151205.200501512.33110-0.327502.518501.55150K562SRFBP1
FBXO18ENSG00000134452.151209.971801690.15400-0.482204.900203.42680K562SRSF5
FBXO18ENSG00000134452.151418.957201786.71420-0.332502.715101.77910K562TRIM56
FBXO18ENSG00000134452.15848.343401122.06380-0.403402.624901.56390K562U2AF1
FBXO18ENSG00000134452.15891.244301158.93330-0.378903.678202.74880K562U2AF2
FBXO18ENSG00000134452.152998.067002441.994600.295905.295904.16140K562WDR43
FBXO18ENSG00000134452.153015.757203756.89430-0.317003.040102.13140K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FBXO18 is not available on ENCORE database.





18 RBPs can affect the splicing of FBXO18 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.086000.001900.03520excludedK562SF3B4
SEFBXO18ENSG00000134452.15chr10+595570959558025952900595309159561405956232-0.133000.000000.00014excludedHepG2U2AF1
SEFBXO18ENSG00000134452.15chr10+596322059633205959552595963959634105963532-0.102000.000020.00069excludedHepG2U2AF1
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.054000.000230.00978excludedK562AKAP8L
SEFBXO18ENSG00000134452.15chr10+5966713596676459662735966471596732959674550.173000.000000.00007includedHepG2HNRNPK
SEFBXO18ENSG00000134452.15chr10+596030459604415959552595963959634105963532-0.182000.011000.09830excludedHepG2U2AF2
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.114000.000000.00000excludedK562PUS1
SEFBXO18ENSG00000134452.15chr10+595574659558025952900595309159561405956232-0.103000.004920.08033excludedK562U2AF1
SEFBXO18ENSG00000134452.15chr10+596030459604415959552595963959632205963320-0.236000.000000.00001excludedK562U2AF1
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.089000.000000.00032excludedHepG2SF3A3
SEFBXO18ENSG00000134452.15chr10+5965583596565959634105963532596627359664710.069000.000070.02705includedK562FXR2
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.060000.000400.01716excludedK562UTP18
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.088000.002060.03591excludedK562U2AF2
SEFBXO18ENSG00000134452.15chr10+596030459604415959552595963959632205963320-0.162000.000020.00063excludedK562U2AF2
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.080000.000000.00011excludedK562RBM15
SEFBXO18ENSG00000134452.15chr10+596030459604415959552595963959632205963320-0.063000.004080.07860excludedK562RBM15
SEFBXO18ENSG00000134452.15chr10+596558359656595963410596353259662735966471-0.095000.000000.00001excludedK562AGGF1
SEFBXO18ENSG00000134452.15chr10+5966713596676459662735966471596732959674550.175000.000020.01410includedK562NCBP2
SEFBXO18ENSG00000134452.15chr10+594799959485955932210593230959508875951018-0.074000.002620.08266excludedK562PTBP1
A3SSFBXO18ENSG00000134452.15chr10+595570959558025955746595580259529005953091-0.156000.000010.00220shorterHepG2SF3A3
A3SSFBXO18ENSG00000134452.15chr10+596627359664715966291596647159655835965659-0.067000.000050.00496shorterK562SF3B4
A3SSFBXO18ENSG00000134452.15chr10+5963388596353259634105963532596322059633200.069000.000030.00500longerHepG2RBM22
A3SSFBXO18ENSG00000134452.15chr10+5979047597909159790725979091597841859785500.129000.000000.00000longerK562AQR
A5SSFBXO18ENSG00000134452.15chr10+5959552595969859595525959639596030459604410.137000.000000.00000longerK562AQR
A5SSFBXO18ENSG00000134452.15chr10+5965583596582959655835965659596627359664710.060000.000000.00005longerK562RBM15
A5SSFBXO18ENSG00000134452.15chr10+5959552595969859595525959639596030459604410.076000.000070.00966longerK562RBM15
A5SSFBXO18ENSG00000134452.15chr10+5978418597862859784185978550597907259795490.056000.000880.07970longerK562EFTUD2
RIFBXO18ENSG00000134452.15chr10+596558359663615965583596565959662915966361-0.117000.000120.00316excludedK562SF3B4
RIFBXO18ENSG00000134452.15chr10+5959398595963959593985959470595955259596390.062000.000480.00747includedHepG2SF3A3
RIFBXO18ENSG00000134452.15chr10+5959343595958459593435959470595955259595840.090000.000000.00000includedK562AQR
MXEFBXO18ENSG00000134452.15chr10+59603045960441596322059633205959552595963959634105963532-0.068000.000650.044412includedK562LARP4
MXEFBXO18ENSG00000134452.15chr10+595290059530915955746595580259511215951257595614059562320.222000.000010.000421includedK562TARDBP
MXEFBXO18ENSG00000134452.15chr10+595290059530915955709595580259511215951257595614059562320.182000.000000.000081includedK562TARDBP
MXEFBXO18ENSG00000134452.15chr10+59603045960441596322059633205959552595963959634105963532-0.056000.010900.057762includedHepG2U2AF2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FBXO18 is not avaliable on ENCORE database.