FAM45A

General Information

Gene Name       : FAM45A
Gene ID             : ENSG00000119979.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM45A)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM45AENSG00000119979.1720.1220.2020.16ENCSR000AEF
HepG2FAM45AENSG00000119979.1719.5528.2723.91ENCSR985KAT
K562FAM45AENSG00000119979.178.478.448.46ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM45A is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM45A RNA is bound by 6 proteins.  







eCLIP assay for FAM45A is not avaliable on ENCORE database.





6 proteins are bound to FAM45A RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr10120867421120867509+5'-UTR,CDS,intron-Proximal4.579374.64001HepG2U2AF2
chr10120863699120863758+5'-UTR,CDS,intron-Proximal3.9337411.26073HepG2PRPF8
chr10120863618120863685+5'-UTR,CDS5.851196.75859HepG2DDX3X
chr10120863687120863722+5'-UTR,CDS,intron-Proximal3.337603.60559HepG2AQR
chr10120864271120864365+intron-Distal,intron-Proximal3.419603.64266HepG2PPIG
chr10120864074120864179+intron-Distal,intron-Proximal4.095985.84043HepG2NKRF
chr10120863722120863747+intron-Proximal3.337603.60559HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM45A is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM45A is not available on ENCORE database.

  • 87 RBPs can affect the levels of FAM45A.  








The Knockdown/knockout RNA-Seq assay for FAM45A is not available on ENCORE database.





87 RBPs can affect the gene expression of FAM45A :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM45AENSG00000119979.11840.722201937.20620-1.2043018.2331016.99480HepG2AKAP1
FAM45AENSG00000119979.111168.14980889.286900.393404.900503.90440HepG2AKAP8L
FAM45AENSG00000119979.111013.384801323.27880-0.384904.847903.98020HepG2AUH
FAM45AENSG00000119979.11380.01620548.29030-0.528902.525701.66610HepG2BCLAF1
FAM45AENSG00000119979.111174.05210877.856100.419304.177003.25390HepG2CALR
FAM45AENSG00000119979.11497.59980884.93420-0.8306017.0789015.73110HepG2CKAP4
FAM45AENSG00000119979.111258.02160745.074900.755609.419708.22320HepG2CPSF6
FAM45AENSG00000119979.111247.010601044.905700.255002.199001.61610HepG2CELF1
FAM45AENSG00000119979.111303.651301123.599100.214302.078001.42230HepG2DAZAP1
FAM45AENSG00000119979.11670.99740818.62000-0.286902.721501.89380HepG2DDX19B
FAM45AENSG00000119979.111377.527901855.75450-0.429903.378102.69600HepG2DDX3X
FAM45AENSG00000119979.11917.12960675.970100.440103.677502.55330HepG2DHX30
FAM45AENSG00000119979.11907.14220700.851400.372103.550202.76030HepG2DNAJC21
FAM45AENSG00000119979.11482.51880694.66030-0.525706.862905.90140HepG2DNAJC2
FAM45AENSG00000119979.111044.534501693.63720-0.697306.864105.85470HepG2EIF4A3
FAM45AENSG00000119979.11790.576101108.44010-0.487606.973505.75550HepG2EIF4G1
FAM45AENSG00000119979.111432.480701061.825300.431903.681602.75040HepG2EIF4G2
FAM45AENSG00000119979.111183.521401519.33270-0.360404.542803.80720HepG2ETF1
FAM45AENSG00000119979.11828.64290638.346100.376302.746001.60620HepG2FASTKD2
FAM45AENSG00000119979.11740.59470516.341500.520304.053502.53860HepG2FKBP4
FAM45AENSG00000119979.11850.493601085.70190-0.352302.642201.87460HepG2FUBP3
FAM45AENSG00000119979.11795.286001708.61220-1.1033018.0895016.49780HepG2FXR1
FAM45AENSG00000119979.111088.810501585.09190-0.541804.704703.84680HepG2G3BP1
FAM45AENSG00000119979.111302.277401682.64300-0.369702.778401.88610HepG2G3BP2
FAM45AENSG00000119979.11789.875901135.71700-0.523903.075901.89800HepG2GRSF1
FAM45AENSG00000119979.11537.76850707.56570-0.395902.760802.11490HepG2HNRNPA1
FAM45AENSG00000119979.11623.87740787.03530-0.335202.055901.44750HepG2HNRNPC
FAM45AENSG00000119979.11862.770601604.80750-0.8954013.6564012.22200HepG2HNRNPK
FAM45AENSG00000119979.11788.442701023.53370-0.376505.106604.21400HepG2HNRNPL
FAM45AENSG00000119979.111336.43510806.018600.729408.459707.42350HepG2HNRNPLL
FAM45AENSG00000119979.11578.33410781.83190-0.435004.948104.15690HepG2HNRNPU
FAM45AENSG00000119979.111030.84100785.612700.391803.117002.35200HepG2IGF2BP1
FAM45AENSG00000119979.111009.299701709.20790-0.760009.055507.88220HepG2MAGOH
FAM45AENSG00000119979.111144.463201718.80610-0.586705.202204.36140HepG2MATR3
FAM45AENSG00000119979.11998.06140787.765800.341302.581201.40880HepG2NAA15
FAM45AENSG00000119979.11910.768701759.31960-0.9499013.1384011.81990HepG2NCBP2
FAM45AENSG00000119979.11911.04540714.688900.350102.278401.59760HepG2NSUN2
FAM45AENSG00000119979.111968.440801121.396700.811705.698704.39000HepG2PABPC1
FAM45AENSG00000119979.111201.602001566.90830-0.383002.702701.98820HepG2PABPC4
FAM45AENSG00000119979.111032.908101547.65550-0.5834011.7546010.64220HepG2PCBP1
FAM45AENSG00000119979.111122.52760808.204100.473902.538201.54440HepG2PCBP2
FAM45AENSG00000119979.111665.738901100.237400.598203.534401.81270HepG2PNPT1
FAM45AENSG00000119979.11339.16390478.70290-0.497102.284601.54720HepG2PRPF8
FAM45AENSG00000119979.11841.197201574.72250-0.9046019.3210018.12100HepG2PTBP1
FAM45AENSG00000119979.11822.495401128.97130-0.456907.608206.72600HepG2PUM1
FAM45AENSG00000119979.11912.300001128.16060-0.306402.592101.94240HepG2PUM2
FAM45AENSG00000119979.111422.362001705.62280-0.262002.546001.94300HepG2QKI
FAM45AENSG00000119979.111243.26760780.104900.672303.792002.97090HepG2RAVER1
FAM45AENSG00000119979.11926.404701269.87440-0.455005.860005.17570HepG2RBM22
FAM45AENSG00000119979.111123.161401547.90210-0.462705.361204.45090HepG2RBM25
FAM45AENSG00000119979.111197.169001752.57710-0.549907.781806.95620HepG2NELFE
FAM45AENSG00000119979.11836.148501632.17470-0.9650024.6063023.08420HepG2RECQL
FAM45AENSG00000119979.111185.06060859.630800.463103.630602.86620HepG2RPLP0
FAM45AENSG00000119979.111043.85750765.991800.446402.208401.36270HepG2RPS10
FAM45AENSG00000119979.11456.91230654.73460-0.519003.585302.89490HepG2RPS19
FAM45AENSG00000119979.11615.08160819.08210-0.413202.548601.77870HepG2RPS2
FAM45AENSG00000119979.11706.183601239.19080-0.811306.832305.74000HepG2SF3A3
FAM45AENSG00000119979.11776.473201639.62360-1.0784027.4744025.94320HepG2SF3B4
FAM45AENSG00000119979.111205.938501019.722200.241902.440601.77580HepG2SLBP
FAM45AENSG00000119979.11686.09640811.95330-0.243002.116801.54310HepG2SMN1
FAM45AENSG00000119979.111217.46330887.691900.455602.364101.64430HepG2SNRNP70
FAM45AENSG00000119979.11908.127601711.35720-0.9142017.3983016.42690HepG2SRSF1
FAM45AENSG00000119979.11999.92900783.874100.351102.684801.99920HepG2SRSF7
FAM45AENSG00000119979.111898.267101392.233100.447208.197807.33780HepG2SRSF9
FAM45AENSG00000119979.111609.975801245.261100.370505.470204.79700HepG2SSB
FAM45AENSG00000119979.11896.865301653.67020-0.8827010.693908.44840HepG2SSRP1
FAM45AENSG00000119979.111146.85490728.980600.653604.218702.72030HepG2SUB1
FAM45AENSG00000119979.111010.693901194.23410-0.240702.529901.93050HepG2SUCLG1
FAM45AENSG00000119979.111181.41080782.743800.593807.175105.71330HepG2SUPT6H
FAM45AENSG00000119979.111146.96910617.544400.8931010.504509.32640HepG2SUPV3L1
FAM45AENSG00000119979.111090.885601538.08270-0.495606.520305.72290HepG2TAF15
FAM45AENSG00000119979.11579.95320413.954100.486403.441502.34100HepG2TFIP11
FAM45AENSG00000119979.11988.24150759.698600.379303.457602.91170HepG2TIAL1
FAM45AENSG00000119979.11747.01750565.635800.401202.240501.34360HepG2UPF2
FAM45AENSG00000119979.11657.826001061.01580-0.6897011.5910010.49890HepG2UTP3
FAM45AENSG00000119979.111482.859101208.660100.294904.200203.56460HepG2ZNF622
FAM45AENSG00000119979.11256.46230385.11940-0.586604.179903.50750K562AGGF1
FAM45AENSG00000119979.11258.45510400.73440-0.632704.189203.38270K562AKAP8L
FAM45AENSG00000119979.11314.15540219.487900.517202.782001.99730K562CPSF6
FAM45AENSG00000119979.11297.66020214.244600.474302.272401.50370K562FIP1L1
FAM45AENSG00000119979.11352.34680223.316400.657803.943902.91940K562FMR1
FAM45AENSG00000119979.11316.14700198.858400.668803.360102.56700K562G3BP2
FAM45AENSG00000119979.11442.75970311.679700.506402.950902.17170K562GRSF1
FAM45AENSG00000119979.11156.25430219.23880-0.488601.892201.38700K562HNRNPC
FAM45AENSG00000119979.11275.81270176.229100.646103.127602.13310K562HNRNPM
FAM45AENSG00000119979.11452.87140290.456300.640704.341103.35110K562HSPD1
FAM45AENSG00000119979.11305.84010204.552600.580203.100902.17080K562METAP2
FAM45AENSG00000119979.11331.13900242.227700.451002.677501.88120K562MTPAP
FAM45AENSG00000119979.11295.28710397.41720-0.428501.888301.42330K562PUS1
FAM45AENSG00000119979.11129.78950206.91190-0.672803.428402.47240K562SF3B4
FAM45AENSG00000119979.11388.79270257.081900.596703.460802.03050K562STAU1
FAM45AENSG00000119979.11261.67140163.714500.676503.215902.11710K562SUPV3L1
FAM45AENSG00000119979.11470.38970285.377000.720907.171206.07870K562UPF1
FAM45AENSG00000119979.11335.47650244.188800.458102.506801.67140K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM45A is not available on ENCORE database.





19 RBPs can affect the splicing of FAM45A :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM45AENSG00000119979.11chr10+120864275120864518120863603120863709120867459120867676-0.279000.001540.08202excludedHepG2RBM22
SEFAM45AENSG00000119979.11chr10+120864275120864534120863606120863709120867459120867608-0.307000.006100.08841excludedHepG2U2AF1
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.284000.000060.00244includedHepG2HNRNPK
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674791208676760.348000.000040.03537includedHepG2LIN28B
SEFAM45AENSG00000119979.11chr10+1208642751208645181208636031208637091208674791208676760.359000.000110.03807includedHepG2BCLAF1
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.459000.001970.02965includedK562PUS1
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.414000.001610.09455includedHepG2HNRNPL
SEFAM45AENSG00000119979.11chr10+120864275120864534120863606120863709120867459120867608-0.445000.000130.00469excludedHepG2SRSF1
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.257000.000360.04777includedHepG2SSB
SEFAM45AENSG00000119979.11chr10+1208642751208645181208636031208637091208674591208676760.458000.000880.03100includedK562UTP18
SEFAM45AENSG00000119979.11chr10+120864275120864518120863603120863709120867479120867676-0.258000.001060.08930excludedHepG2TAF15
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.602000.001900.04449includedK562RBM15
SEFAM45AENSG00000119979.11chr10+1208642751208645341208636061208637091208674591208676080.503000.000770.02251includedK562AGGF1
SEFAM45AENSG00000119979.11chr10+1208642751208645181208636031208637091208674791208676760.293000.000220.07242includedHepG2XRN2
MXEFAM45AENSG00000119979.11chr10+1208770301208771791208798521208799641208713601208714401208829801208830810.152000.000240.006721includedHepG2U2AF1
MXEFAM45AENSG00000119979.11chr10+1208770301208771791208798521208799641208713601208714401208829801208830810.283000.000040.001941includedHepG2FTO
MXEFAM45AENSG00000119979.11chr10+120882980120883081120889026120889134120879852120879964120892026120892121-0.111000.004800.071262includedHepG2FTO
MXEFAM45AENSG00000119979.11chr10+1208770301208771791208798521208799641208713601208714401208829801208830810.307000.003300.041031includedK562U2AF2
MXEFAM45AENSG00000119979.11chr10+120867459120867676120871360120871440120863628120863709120877030120877179-0.131000.001600.036572includedHepG2DDX55
MXEFAM45AENSG00000119979.11chr10+1208770301208771791208798521208799641208713601208714401208829801208830810.096000.020280.093501includedHepG2U2AF2
MXEFAM45AENSG00000119979.11chr10+1208770301208771791208798521208799641208713601208714401208829801208830810.231000.001960.073551includedHepG2DROSHA
MXEFAM45AENSG00000119979.11chr10+1208890261208890551208920261208921211208829801208830811208965681208966920.576000.001080.020001includedHepG2HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM45A is not avaliable on ENCORE database.