COG4

General Information

Gene Name       : COG4
Gene ID             : ENSG00000103051.18
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COG4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COG4ENSG00000103051.1814.0817.0415.56ENCSR000AEF
HepG2COG4ENSG00000103051.1849.7041.5945.65ENCSR985KAT
K562COG4ENSG00000103051.1835.3029.7432.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COG4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COG4 RNA is bound by 23 proteins.  







eCLIP assay for COG4 is not avaliable on ENCORE database.





23 proteins are bound to COG4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr167051479570514902-3'-UTR,intron-Distal3.590107.08459HepG2LSM11
chr167053192170531937-3'-UTR,CDS,intron-Distal4.792205.86613HepG2PPIG
chr167053486070534917-3'-UTR,CDS,intron-Distal,intron-Proximal3.167408.27894HepG2BCLAF1
chr167054830870548340-3'-UTR,5'-UTR,CDS,intron-Distal4.311747.79455HepG2PPIG
chr167051460070514794-3'-UTR,intron-Distal,intron-Proximal4.872257.70160HepG2UPF1
chr167051538570515428-3'-UTR,CDS,intron-Distal,intron-Proximal3.742644.77481HepG2BUD13
chr167051771270517788-3'-UTR,CDS,intron-Distal,intron-Proximal4.9892119.05983HepG2PRPF8
chr167051569270515756-3'-UTR,CDS,intron-Distal3.6637911.37584K562YBX3
chr167052423370524276-3'-UTR,CDS,intron-Distal4.6524411.01413HepG2PPIG
chr167051782170517864-3'-UTR,CDS,intron-Distal3.173813.85127HepG2GRWD1
chr167051526170515294-3'-UTR,CDS,intron-Distal,intron-Proximal3.035653.46769K562YBX3
chr167054265470542753-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0158318.29253HepG2U2AF2
chr167055152870551599-3'-UTR,CDS,intron-Distal,intron-Proximal3.5706114.44526HepG2BCLAF1
chr167051534270515385-3'-UTR,CDS,intron-Distal3.713196.06370HepG2BUD13
chr167054829870548354-3'-UTR,5'-UTR,CDS,intron-Distal4.513736.03821HepG2GRWD1
chr167051481670514883-3'-UTR,intron-Distal3.417143.03634HepG2PABPN1
chr167053486370534925-3'-UTR,CDS,intron-Distal3.718018.07380HepG2GRWD1
chr167051536870515442-3'-UTR,CDS,intron-Distal,intron-Proximal4.5609810.75758HepG2SF3B4
chr167054824870548297-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.135433.35081HepG2G3BP1
chr167055153270551590-3'-UTR,CDS,intron-Distal3.8930110.69967HepG2PPIG
chr167054614270546178-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.505339.15113HepG2PPIG
chr167051575670515766-3'-UTR,CDS,intron-Distal4.727946.16445HepG2PPIG
chr167053486170534911-3'-UTR,CDS,intron-Distal4.4228014.26247HepG2PPIG
chr167051456170514618-3'-UTR,intron-Distal4.944937.79810K562TROVE2
chr167053021570530322-3'-UTR,CDS,intron-Distal,intron-Proximal3.158635.82330K562YBX3
chr167053486270534910-3'-UTR,CDS,intron-Distal4.458384.83675HepG2G3BP1
chr167051599370516016-3'-UTR,CDS,intron-Distal,intron-Proximal3.846463.67607K562YBX3
chr167051461870514624-3'-UTR,intron-Distal5.534786.33480K562TROVE2
chr167051783170517861-3'-UTR,CDS,intron-Distal4.275615.86107HepG2PPIG
chr167051469570514798-3'-UTR,intron-Distal,intron-Proximal4.052185.82560HepG2PABPN1
chr167053014870530198-3'-UTR,CDS,intron-Distal,intron-Proximal4.261776.34662HepG2PRPF8
chr167051603270516074-3'-UTR,CDS,intron-Distal4.710949.58174HepG2PPIG
chr167051599870516032-3'-UTR,CDS,intron-Distal5.6619111.86816HepG2PPIG
chr167054823970548294-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.7131411.10779HepG2BCLAF1
chr167053492570534992-3'-UTR,CDS,intron-Distal3.8727910.05825HepG2GRWD1
chr167051567870515712-3'-UTR,CDS,intron-Distal3.351836.27819HepG2PPIG
chr167051503270515045-3'-UTR,CDS,intron-Distal3.771414.13746HepG2PPIG
chr167051479470514878-3'-UTR,intron-Distal4.062013.45012HepG2UPF1
chr167051786370517872-3'-UTR,CDS,intron-Distal4.612816.36347HepG2PPIG
chr167051526270515308-3'-UTR,CDS,intron-Distal3.009026.70027HepG2PPIG
chr167054628470546318-3'-UTR,5'-UTR,CDS,intron-Distal4.083556.65960HepG2BCLAF1
chr167051536970515439-3'-UTR,CDS,intron-Distal,intron-Proximal4.9751311.07190HepG2SF3A3
chr167053496870535038-3'-UTR,CDS,intron-Distal,intron-Proximal4.411085.47926K562AQR
chr167051594970516020-3'-UTR,CDS,intron-Distal,intron-Proximal5.0113814.79448HepG2PRPF8
chr167053491170534990-3'-UTR,CDS,intron-Distal3.7586414.72800HepG2PPIG
chr167053189770531940-3'-UTR,CDS,intron-Distal4.157823.01428K562UCHL5
chr167051603070516076-3'-UTR,CDS,intron-Distal4.176484.67299K562DDX24
chr167051671470516820-3'-UTR,CDS,intron-Distal,intron-Proximal4.552964.79286HepG2PRPF4
chr167051599670516079-3'-UTR,CDS,intron-Distal,intron-Proximal3.280634.63930HepG2PABPN1
chr167051663470516672-3'-UTR,CDS,intron-Distal3.920913.86978K562YBX3
chr167051486670514927-3'-UTR,CDS,intron-Distal3.165183.24816K562YBX3
chr167054381870543851-5'-UTR,CDS,intron-Distal,intron-Proximal3.170215.56979K562YBX3
chr167054390870543923-5'-UTR,CDS,intron-Distal3.613905.15776HepG2BCLAF1
chr167054381970543847-5'-UTR,CDS,intron-Distal3.384417.20311HepG2PPIG
chr167054619570546204-5'-UTR,CDS,intron-Distal,intron-Proximal4.073754.32914K562YBX3
chr167054387470543920-5'-UTR,CDS,intron-Distal4.663253.02297K562DDX24
chr167054381770543851-5'-UTR,CDS,intron-Distal,intron-Proximal3.527295.14253HepG2GRWD1
chr167054321970543280-5'-UTR,CDS,intron-Distal3.742566.18214HepG2GRWD1
chr167054614170546160-5'-UTR,CDS,intron-Distal,intron-Proximal3.630115.97823HepG2BCLAF1
chr167054389870543923-5'-UTR,CDS,intron-Distal4.430969.41951HepG2PPIG
chr167054308170543152-5'-UTR,CDS,intron-Distal,intron-Proximal3.3944013.27450HepG2PRPF8
chr167054326770543291-5'-UTR,CDS,intron-Distal4.333864.72754K562YBX3
chr167054317270543203-5'-UTR,CDS,intron-Distal3.445385.15776HepG2BCLAF1
chr167054236170542422-5'-UTR,CDS,intron-Distal,intron-Proximal5.4464921.46511HepG2SF3A3
chr167054304370543136-5'-UTR,CDS,intron-Distal,intron-Proximal3.049414.60947K562AQR
chr167051559970515653-intron-Distal,intron-Proximal3.995623.12843K562PRPF8
chr167051556070515615-intron-Distal,intron-Proximal4.117965.42009HepG2EFTUD2
chr167054304070543103-intron-Distal,intron-Proximal3.319367.70439HepG2BCLAF1
chr167054304070543110-intron-Distal,intron-Proximal4.275824.19412K562EFTUD2
chr167054304970543106-intron-Distal,intron-Proximal3.836474.83172HepG2RBM22
chr167054682070546889-intron-Distal4.365725.87146HepG2HNRNPC
chr167051546870515574-intron-Distal,intron-Proximal4.096426.61691HepG2RBFOX2
chr167051674170516816-intron-Distal,intron-Proximal4.729444.86316HepG2FAM120A
chr167051763570517704-intron-Distal,intron-Proximal4.4194010.22430HepG2EFTUD2
chr167054294270543028-intron-Distal3.013723.40058K562PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COG4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COG4 is not available on ENCORE database.

  • 59 RBPs can affect the levels of COG4.  








The Knockdown/knockout RNA-Seq assay for COG4 is not available on ENCORE database.





59 RBPs can affect the gene expression of COG4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COG4ENSG00000103051.141732.624401355.204900.354302.346301.47670HepG2ABCF1
COG4ENSG00000103051.142118.626602437.03400-0.202002.116301.50150HepG2AUH
COG4ENSG00000103051.141045.73070758.419800.463303.963903.26070HepG2BOP1
COG4ENSG00000103051.141819.652401606.038600.180101.987601.41210HepG2CKAP4
COG4ENSG00000103051.141730.070301010.740400.775305.749904.64790HepG2CNOT7
COG4ENSG00000103051.141252.04720872.252300.521404.864003.49120HepG2CSTF2
COG4ENSG00000103051.142654.557602252.155100.237104.170403.28920HepG2DAZAP1
COG4ENSG00000103051.141051.669001318.31220-0.326002.481701.83610HepG2DDX21
COG4ENSG00000103051.141081.504401388.56020-0.360602.306701.59460HepG2DDX55
COG4ENSG00000103051.141264.841501790.61190-0.501503.874403.15340HepG2DDX6
COG4ENSG00000103051.141857.023601536.976300.272803.269602.54320HepG2DKC1
COG4ENSG00000103051.14927.858101091.55840-0.234402.347201.73640HepG2DNAJC2
COG4ENSG00000103051.141586.962001245.229900.349803.413302.23230HepG2EIF3G
COG4ENSG00000103051.142757.424901902.401100.535404.824803.98390HepG2EIF4A3
COG4ENSG00000103051.141338.489001852.19780-0.468602.887702.18590HepG2EIF4B
COG4ENSG00000103051.141676.037802069.94130-0.304503.745802.68410HepG2HNRNPA2B1
COG4ENSG00000103051.142407.606601802.836400.417204.061103.22860HepG2HNRNPK
COG4ENSG00000103051.141582.600602051.44890-0.374305.231504.32930HepG2HNRNPL
COG4ENSG00000103051.14953.70870753.181800.340502.070001.51730HepG2HNRNPLL
COG4ENSG00000103051.141476.575901254.990000.234502.761402.02930HepG2ILF2
COG4ENSG00000103051.141499.941201930.78360-0.364302.358501.77280HepG2MATR3
COG4ENSG00000103051.14870.492601107.30580-0.347102.869802.04670HepG2MSI2
COG4ENSG00000103051.14619.03150923.73190-0.577502.873501.96770HepG2PABPC1
COG4ENSG00000103051.141601.465801841.92300-0.201802.065201.52820HepG2PCBP1
COG4ENSG00000103051.141332.062201025.142900.377703.909703.00530HepG2PRPF4
COG4ENSG00000103051.141595.557401874.22550-0.232202.622802.08790HepG2PTBP1
COG4ENSG00000103051.141669.070202263.22050-0.439307.258206.39210HepG2PUM1
COG4ENSG00000103051.142001.188001636.333200.290304.240903.50700HepG2PUS1
COG4ENSG00000103051.141176.639301495.16940-0.345603.346802.41220HepG2RBM15
COG4ENSG00000103051.141820.569802338.62680-0.361304.851404.21390HepG2RBM22
COG4ENSG00000103051.141544.366001842.20350-0.254402.033801.45010HepG2RBM25
COG4ENSG00000103051.141399.930301724.85680-0.301102.296301.40150HepG2RBM27
COG4ENSG00000103051.14654.63480891.98010-0.446303.946403.22510HepG2RPS19
COG4ENSG00000103051.141408.209001951.31070-0.470608.541707.59140HepG2SF3B4
COG4ENSG00000103051.141198.92060829.487100.531302.950502.14190HepG2SNRNP70
COG4ENSG00000103051.142190.541902641.40340-0.270003.864003.30170HepG2SRFBP1
COG4ENSG00000103051.14498.69380802.19420-0.685804.836803.48170HepG2SRSF3
COG4ENSG00000103051.141049.827601365.56940-0.379404.964704.07420HepG2SRSF7
COG4ENSG00000103051.141301.492101657.00130-0.348405.184704.47130HepG2SRSF9
COG4ENSG00000103051.143054.020102293.381800.413108.957708.13700HepG2SSB
COG4ENSG00000103051.14845.276201220.97000-0.530503.051401.78570HepG2SUB1
COG4ENSG00000103051.141452.381201830.70660-0.334003.984003.33020HepG2TAF15
COG4ENSG00000103051.141232.873901682.17000-0.448305.429204.27010HepG2TIA1
COG4ENSG00000103051.141615.168301193.943000.435905.287904.64230HepG2TIAL1
COG4ENSG00000103051.14834.213601308.40770-0.6493012.7539011.60930HepG2UTP3
COG4ENSG00000103051.141902.751201360.669500.483704.109603.23420HepG2XRN2
COG4ENSG00000103051.14739.293401305.61380-0.820507.517805.26100HepG2ZRANB2
COG4ENSG00000103051.142153.496201860.732600.210702.215201.69790K562AGGF1
COG4ENSG00000103051.141413.248302505.54520-0.8261013.6186012.45750K562AQR
COG4ENSG00000103051.142174.317001590.958800.450608.279607.23170K562DDX47
COG4ENSG00000103051.142074.624901412.103100.554904.178402.57250K562EEF2
COG4ENSG00000103051.141353.882801025.786800.400304.493503.48980K562EIF3G
COG4ENSG00000103051.141407.214201068.365600.397303.528402.56100K562FIP1L1
COG4ENSG00000103051.14663.31190998.30320-0.589802.803602.08970K562G3BP2
COG4ENSG00000103051.142003.008201462.724200.453403.800402.82560K562PCBP3
COG4ENSG00000103051.141694.930301121.981900.595104.872103.80680K562POLR2G
COG4ENSG00000103051.141071.371101327.48940-0.309202.189501.51800K562PRPF8
COG4ENSG00000103051.142530.372603042.28050-0.265802.145101.42780K562PUF60
COG4ENSG00000103051.141178.311301480.62410-0.329502.603401.79040K562RBM22
COG4ENSG00000103051.14434.17980651.14170-0.584703.861802.70030K562SF3B1
COG4ENSG00000103051.14761.385401037.84680-0.446904.750003.61860K562SF3B4
COG4ENSG00000103051.141730.345301403.615400.301804.426603.37420K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COG4 is not available on ENCORE database.





26 RBPs can affect the splicing of COG4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOG4ENSG00000103051.14chr16-7054977070549943705482377054841270551528705516430.074000.000830.06626includedHepG2QKI
SECOG4ENSG00000103051.14chr16-705497707054994370548237705484127055152870551643-0.064000.000020.00303excludedHepG2AKAP1
SECOG4ENSG00000103051.14chr16-7054977070549943705482377054841270551528705516430.060000.001250.01471includedK562AQR
SECOG4ENSG00000103051.14chr16-7054977070549943705482377054841270551528705516430.084000.000510.08986includedHepG2UCHL5
SECOG4ENSG00000103051.14chr16-7054977070549943705482377054841270551528705516430.183000.000010.00356includedHepG2TAF15
A3SSCOG4ENSG00000103051.14chr16-705301687053033470530168705302827053112370531290-0.095000.000120.05241shorterHepG2IGF2BP3
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.133000.000280.03562includedK562APOBEC3C
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.185000.000720.03999includedHepG2BCCIP
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.246000.002700.04837includedHepG2PCBP2
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.154000.000000.00004excludedK562PUS1
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.233000.000690.00988excludedHepG2SF3A3
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.489000.000000.00000includedHepG2UCHL5
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.237000.003560.04123includedHepG2PRPF8
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.204000.000300.01654excludedK562HNRNPUL1
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.159000.000000.00005excludedK562AGGF1
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.163000.001970.03868includedHepG2IGF2BP3
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.199000.000370.01612includedHepG2MATR3
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.153000.000360.00562includedHepG2QKI
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.122000.004010.06969includedK562RBM22
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.106000.004220.03809excludedK562AKAP8L
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.166000.000970.01163includedHepG2TAF15
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.138000.000130.00225excludedK562RBM15
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.328000.000000.00001includedHepG2G3BP1
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.159000.000010.00364excludedK562TROVE2
RICOG4ENSG00000103051.14chr16-705423087054329170542308705423677054313370543291-0.212000.001430.05855excludedHepG2HNRNPC
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.238000.000060.01747includedK562WDR43
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.260000.000000.00008includedHepG2HNRNPK
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.159000.000200.01121includedK562TARDBP
RICOG4ENSG00000103051.14chr16-7054230870543291705423087054236770543133705432910.245000.000010.00166includedHepG2XRN2
MXECOG4ENSG00000103051.14chr16-7053486070534994705423087054236770531839705319587054313370543291-0.166000.001160.026792includedHepG2SRSF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COG4 is not avaliable on ENCORE database.