CLK4

General Information

Gene Name       : CLK4
Gene ID             : ENSG00000113240.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CLK4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CLK4ENSG00000113240.1214.5411.0412.79ENCSR000AEF
HepG2CLK4ENSG00000113240.128.4312.5910.51ENCSR985KAT
K562CLK4ENSG00000113240.126.957.036.99ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CLK4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CLK4 RNA is bound by 10 proteins.  







eCLIP assay for CLK4 is not avaliable on ENCORE database.





10 proteins are bound to CLK4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5178030424178030521-3'-UTR,intron-Distal4.109104.58794K562KHSRP
chr5178039795178039856-3'-UTR,CDS,intron-Distal,intron-Proximal4.8903210.64218HepG2BCLAF1
chr5178040613178040642-3'-UTR,CDS,intron-Distal,intron-Proximal3.138083.94979HepG2BCLAF1
chr5178035340178035389-3'-UTR,CDS,intron-Distal,intron-Proximal3.515954.35635K562PRPF8
chr5178039476178039548-3'-UTR,CDS,intron-Distal,intron-Proximal5.698869.32793HepG2BCLAF1
chr5178032305178032373-3'-UTR,CDS,intron-Distal3.930564.93978HepG2BCLAF1
chr5178040812178040846-3'-UTR,CDS,intron-Distal,intron-Proximal4.150847.09561HepG2BCLAF1
chr5178035339178035393-3'-UTR,CDS,intron-Distal,intron-Proximal6.137159.40852HepG2PRPF8
chr5178039383178039460-3'-UTR,CDS,intron-Distal,intron-Proximal5.8732924.01948HepG2PRPF8
chr5178039831178039873-3'-UTR,CDS,intron-Distal3.346093.55754HepG2U2AF2
chr5178045677178045802-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.569126.12893K562BUD13
chr5178030708178030776-3'-UTR,CDS,intron-Distal,intron-Proximal3.408863.62357HepG2U2AF2
chr5178030629178030761-3'-UTR,CDS,intron-Distal,intron-Proximal5.7728111.17302HepG2BCLAF1
chr5178040724178040770-3'-UTR,CDS,intron-Distal,intron-Proximal3.254376.59678HepG2BCLAF1
chr5178040544178040597-3'-UTR,CDS,intron-Distal4.554104.78529HepG2BCLAF1
chr5178030837178030913-3'-UTR,CDS,intron-Distal,intron-Proximal4.083556.65960HepG2BCLAF1
chr5178046796178046858-3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.646258.11807HepG2PRPF8
chr5178032321178032436-3'-UTR,CDS,intron-Distal,intron-Proximal3.498194.94119K562SF3B4
chr5178045693178045781-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.927918.51432HepG2BCLAF1
chr5178043886178044020-5'-UTR,CDS,intron-Distal,intron-Proximal4.019477.50982HepG2AQR
chr5178043879178043944-5'-UTR,CDS,intron-Distal,intron-Proximal3.263226.50801HepG2BCLAF1
chr5178043902178044001-5'-UTR,CDS,intron-Distal,intron-Proximal4.889209.53610K562SF3B4
chr5178043884178043960-5'-UTR,CDS,intron-Distal,intron-Proximal3.028013.95327HepG2PPIG
chr5178045636178045691-5'-UTR,CDS,intron-Distal,intron-Proximal4.007524.04622HepG2GRWD1
chr5178045578178045636-5'-UTR,CDS,intron-Distal,intron-Proximal4.806216.94886HepG2GRWD1
chr5178053942178054039-5'-UTR,intron-Distal,intron-Proximal3.217247.18294HepG2NCBP2
chr5178046805178046839-intron-Distal,intron-Proximal4.384434.21433K562PRPF8
chr5178045487178045557-intron-Distal,intron-Proximal4.066315.97994K562AQR
chr5178046790178046827-intron-Distal,intron-Proximal3.895794.52312K562AQR
chr5178039311178039378-intron-Distal,intron-Proximal4.288113.89565K562PRPF8
chr5178046827178046839-intron-Distal,intron-Proximal4.623634.09264K562AQR
chr5178044589178044707-intron-Distal,intron-Proximal3.009575.10035K562KHSRP
chr5178045810178045882-intron-Distal,intron-Proximal4.128874.31512K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CLK4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CLK4 is not available on ENCORE database.

  • 70 RBPs can affect the levels of CLK4.  








The Knockdown/knockout RNA-Seq assay for CLK4 is not available on ENCORE database.





70 RBPs can affect the gene expression of CLK4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CLK4ENSG00000113240.8544.46820422.766600.364902.736501.97340HepG2AKAP8L
CLK4ENSG00000113240.8391.74200274.761400.511602.763801.86530HepG2BCLAF1
CLK4ENSG00000113240.8643.30430439.067800.551004.354403.62340HepG2BOP1
CLK4ENSG00000113240.8615.93410442.695100.476403.170302.34950HepG2CALR
CLK4ENSG00000113240.8510.70390420.697900.279601.872001.31060HepG2CKAP4
CLK4ENSG00000113240.8449.42760312.127400.525903.414502.66750HepG2DDX21
CLK4ENSG00000113240.8495.26680310.854300.671904.315703.37280HepG2DDX55
CLK4ENSG00000113240.8561.19120357.084600.652102.747802.13220HepG2DDX6
CLK4ENSG00000113240.8567.67440402.582500.495704.390303.57350HepG2DKC1
CLK4ENSG00000113240.8461.99430343.249500.428502.127301.59950HepG2EIF2S1
CLK4ENSG00000113240.8502.35530379.319100.405201.907701.37290HepG2EIF4A3
CLK4ENSG00000113240.8861.87300531.386300.6976010.342108.92000HepG2EIF4G1
CLK4ENSG00000113240.8837.44670604.521100.470105.325704.53970HepG2ETF1
CLK4ENSG00000113240.8728.31820403.768600.850903.484402.33970HepG2FTO
CLK4ENSG00000113240.8541.61840355.040700.609204.037403.24230HepG2G3BP1
CLK4ENSG00000113240.8521.32550359.555200.535903.414802.64170HepG2HNRNPK
CLK4ENSG00000113240.8597.74560436.091700.454802.770802.14070HepG2HNRNPLL
CLK4ENSG00000113240.8245.84530398.95840-0.698504.554403.79280HepG2HNRNPU
CLK4ENSG00000113240.8583.84170416.743700.486303.517402.60620HepG2MSI2
CLK4ENSG00000113240.8472.49790349.932900.433102.642301.45530HepG2NAA15
CLK4ENSG00000113240.8645.83640400.851900.688003.543802.53040HepG2PABPC1
CLK4ENSG00000113240.8669.43300381.978500.809305.594304.15850HepG2PCBP2
CLK4ENSG00000113240.8434.26460239.876800.856206.583805.39830HepG2PRPF8
CLK4ENSG00000113240.8508.78260376.849500.433003.366902.77560HepG2PTBP1
CLK4ENSG00000113240.8792.11980408.129800.9566014.4306013.16130HepG2QKI
CLK4ENSG00000113240.8670.98420368.646400.863905.001504.06840HepG2RAVER1
CLK4ENSG00000113240.8965.88580505.271000.9347017.1107016.04630HepG2RBM22
CLK4ENSG00000113240.8559.57160370.406800.595104.921604.04560HepG2RBM25
CLK4ENSG00000113240.8656.79000415.002000.662205.850304.90990HepG2RPLP0
CLK4ENSG00000113240.8464.56910237.295400.969107.764806.53090HepG2RRP9
CLK4ENSG00000113240.8597.52390419.391300.510602.604501.94950HepG2SF3A3
CLK4ENSG00000113240.8697.36120480.291900.537902.641501.87860HepG2SNRNP70
CLK4ENSG00000113240.8826.45540570.690900.534106.972206.27720HepG2SRFBP1
CLK4ENSG00000113240.8317.62100409.52330-0.366602.072001.64640HepG2SRSF1
CLK4ENSG00000113240.8637.44360503.399400.340502.652102.03620HepG2SRSF5
CLK4ENSG00000113240.8576.41630333.171300.7907010.870709.90340HepG2SRSF9
CLK4ENSG00000113240.8870.57610495.505000.8130015.0773014.07300HepG2SSB
CLK4ENSG00000113240.8565.50530309.473200.869606.961505.96570HepG2SUPV3L1
CLK4ENSG00000113240.8534.43290368.102700.537804.587203.89340HepG2TAF15
CLK4ENSG00000113240.8743.89360424.984300.807608.673207.48910HepG2TARDBP
CLK4ENSG00000113240.8606.96300387.745800.646406.562805.85320HepG2TIAL1
CLK4ENSG00000113240.8994.87860440.464801.1754017.2537015.63350HepG2U2AF1
CLK4ENSG00000113240.8477.06920371.936600.359002.525301.85290HepG2UPF1
CLK4ENSG00000113240.8499.91120332.006600.590405.892504.96900HepG2ZC3H8
CLK4ENSG00000113240.8838.22570409.058201.0349024.3191023.10160HepG2ZNF622
CLK4ENSG00000113240.8857.59000602.248400.509806.193505.39650K562AGGF1
CLK4ENSG00000113240.8990.36060626.668900.660207.573006.44510K562AKAP8L
CLK4ENSG00000113240.81210.36720616.188300.9739014.2413013.05550K562AQR
CLK4ENSG00000113240.81364.381701039.521700.392204.266103.04610K562CELF1
CLK4ENSG00000113240.8504.62750330.879200.608804.081902.67790K562FKBP4
CLK4ENSG00000113240.8560.75470422.337700.408902.855001.76510K562HNRNPA1
CLK4ENSG00000113240.81042.65590600.603100.795703.783702.28070K562HNRNPA2B1
CLK4ENSG00000113240.8457.88730631.84900-0.464603.537602.32550K562HNRNPL
CLK4ENSG00000113240.81059.32710665.044800.671508.379406.74270K562KIF1C
CLK4ENSG00000113240.8343.00250508.15060-0.567004.188103.14940K562MAGOH
CLK4ENSG00000113240.8391.57900507.15860-0.373102.234301.41270K562MATR3
CLK4ENSG00000113240.8332.02230460.27260-0.471202.894401.99740K562METAP2
CLK4ENSG00000113240.8975.28600522.205200.901104.242403.08020K562NAA15
CLK4ENSG00000113240.8548.25930431.221200.346302.679201.94330K562NSUN2
CLK4ENSG00000113240.8788.12710525.371100.585002.187401.32880K562PABPN1
CLK4ENSG00000113240.8693.30210478.603600.534603.570302.62500K562PCBP3
CLK4ENSG00000113240.8458.77850288.528800.669004.472703.51990K562PRPF8
CLK4ENSG00000113240.8234.37610493.68100-1.0748012.2561010.90930K562PTBP1
CLK4ENSG00000113240.81241.28270621.468300.9980015.3928014.15230K562PUS1
CLK4ENSG00000113240.8957.55190605.539900.661009.188508.13140K562RBM15
CLK4ENSG00000113240.8567.19630435.919200.379703.076402.09430K562SRPK2
CLK4ENSG00000113240.8321.05860483.94320-0.592004.495303.59830K562SRSF1
CLK4ENSG00000113240.8357.45990545.92560-0.610904.524603.12380K562SRSF4
CLK4ENSG00000113240.8277.11490368.21570-0.410102.205501.47120K562SYNCRIP
CLK4ENSG00000113240.8347.03440489.84400-0.497203.159502.40320K562TARDBP
CLK4ENSG00000113240.8336.48330472.49360-0.489803.350502.43820K562TIA1
CLK4ENSG00000113240.8614.01320443.459400.469402.726201.64210K562U2AF1
CLK4ENSG00000113240.8676.02830458.094200.561304.603903.57450K562U2AF2
CLK4ENSG00000113240.8648.16840391.240600.728207.802606.28650K562WDR3
CLK4ENSG00000113240.8610.14820406.834000.584606.855905.57740K562WDR43
CLK4ENSG00000113240.8924.85520730.280600.340702.618501.36870K562WRN
CLK4ENSG00000113240.8188.34440301.06750-0.676703.748202.26280K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CLK4 is not available on ENCORE database.





26 RBPs can affect the splicing of CLK4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECLK4ENSG00000113240.8chr5-1780468381780468971780443441780457791780502561780504170.291000.000230.01955includedHepG2RBM22
SECLK4ENSG00000113240.8chr5-178046838178046897178044344178045779178050256178050417-0.148000.000080.00226excludedHepG2U2AF1
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.165000.000230.00988excludedK562AKAP8L
SECLK4ENSG00000113240.8chr5-178046838178046897178044344178045779178050256178050417-0.163000.000070.00400excludedK562AKAP8L
SECLK4ENSG00000113240.8chr5-1780328251780328661780323031780323831780353761780354590.219000.000250.02804includedK562XRCC6
SECLK4ENSG00000113240.8chr5-1780468381780476741780455561780457791780502561780504170.202000.004760.09230includedHepG2HNRNPK
SECLK4ENSG00000113240.8chr5-178046838178046897178044344178045779178050256178050417-0.222000.001250.01709excludedHepG2U2AF2
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.222000.000060.00108excludedK562AQR
SECLK4ENSG00000113240.8chr5-178046838178046897178044344178045779178050256178050417-0.112000.012470.09671excludedK562AQR
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.323000.000000.00000excludedK562PUS1
SECLK4ENSG00000113240.8chr5-178046838178046897178044344178045779178050256178050417-0.147000.000040.00116excludedK562PUS1
SECLK4ENSG00000113240.8chr5-1780468381780476741780455561780457791780502561780504170.299000.000050.02745includedK562KHSRP
SECLK4ENSG00000113240.8chr5-178046838178047674178045556178045779178050256178050417-0.175000.000060.01837excludedK562LARP4
SECLK4ENSG00000113240.8chr5-1780493931780494601780455561780457791780502561780504170.225000.000000.00076includedK562EIF4G2
SECLK4ENSG00000113240.8chr5-178044344178044435178043882178043949178045556178045779-0.245000.000220.04222excludedK562EIF4G2
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.230000.000100.00554excludedK562UTP18
SECLK4ENSG00000113240.8chr5-178049393178049460178045556178045779178050256178050417-0.081000.003850.09198excludedK562UTP18
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.195000.000020.00100excludedK562RBM15
SECLK4ENSG00000113240.8chr5-178035376178035459178032303178032383178039416178039546-0.296000.000000.00000excludedK562AGGF1
SECLK4ENSG00000113240.8chr5-1780468381780468971780443441780457791780502561780504170.332000.002080.06817includedHepG2HNRNPC
SECLK4ENSG00000113240.8chr5-1780468381780468971780443441780457791780502561780504170.456000.000000.00077includedHepG2KHSRP
SECLK4ENSG00000113240.8chr5-1780468381780476741780455561780457791780502561780504170.357000.000070.00463includedK562PTBP1
SECLK4ENSG00000113240.8chr5-178044344178044435178043882178043949178045556178045779-0.414000.000380.01893excludedK562PTBP1
SECLK4ENSG00000113240.8chr5-1780468381780468971780443441780457791780502561780504170.334000.002100.03538includedK562HNRNPC
A5SSCLK4ENSG00000113240.8chr5-178044344178045779178045556178045779178043882178043949-0.442000.000690.07215shorterK562PTBP1
RICLK4ENSG00000113240.8chr5-178043882178045779178043882178043949178045556178045779-0.375000.000020.00877excludedHepG2XPO5
RICLK4ENSG00000113240.8chr5-178044344178045779178044344178044435178045556178045779-0.142000.001390.04684excludedK562HNRNPUL1
RICLK4ENSG00000113240.8chr5-1780443441780457791780443441780444351780455561780457790.190000.000350.04876includedHepG2DROSHA
RICLK4ENSG00000113240.8chr5-1780443441780457791780443441780444351780455561780457790.183000.008590.07635includedHepG2QKI
RICLK4ENSG00000113240.8chr5-178044344178045779178044344178044435178045556178045779-0.100000.000510.00626excludedK562AKAP8L
RICLK4ENSG00000113240.8chr5-178044344178045779178044344178044435178045556178045779-0.134000.003180.03135excludedHepG2U2AF1
RICLK4ENSG00000113240.8chr5-178044344178045779178044344178044435178045556178045779-0.098000.001560.01867excludedK562RBM15
RICLK4ENSG00000113240.8chr5-1780438821780457791780438821780439491780443441780457790.347000.000470.01141includedHepG2G3BP1
RICLK4ENSG00000113240.8chr5-1780438821780457791780438821780439491780443441780457790.241000.001980.03640includedK562U2AF1
RICLK4ENSG00000113240.8chr5-1780438821780457791780438821780439491780443441780457790.337000.003910.05821includedHepG2TIAL1
RICLK4ENSG00000113240.8chr5-1780443441780457791780443441780444351780455561780457790.226000.003200.02440includedHepG2SF3B4
RICLK4ENSG00000113240.8chr5-178044344178045779178044344178044435178045556178045779-0.206000.000570.08147excludedHepG2SRSF7
RICLK4ENSG00000113240.8chr5-1780438821780457791780438821780439491780443441780457790.239000.001210.08431includedK562PUM1
RICLK4ENSG00000113240.8chr5-178043882178045779178043882178043949178045556178045779-0.220000.016870.08488excludedK562AQR
RICLK4ENSG00000113240.8chr5-1780443441780457791780443441780444351780455561780457790.209000.001020.05738includedHepG2SSB
RICLK4ENSG00000113240.8chr5-178043882178045779178043882178043949178045556178045779-0.492000.000080.00286excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CLK4 is not avaliable on ENCORE database.