CKLF

General Information

Gene Name       : CKLF
Gene ID             : ENSG00000217555.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CKLF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CKLFENSG00000217555.1215.1840.8428.01ENCSR000AEF
HepG2CKLFENSG00000217555.1298.0981.0789.58ENCSR985KAT
K562CKLFENSG00000217555.1288.5679.6484.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CKLF is not avaliable on ENCORE database.



Proteins bound to RNA
  • CKLF RNA is bound by 6 proteins.  







eCLIP assay for CKLF is not avaliable on ENCORE database.





6 proteins are bound to CKLF RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166658649966586687+5'-UTR,CDS4.7998737.26274K562DDX3X
chr166658653266586650+5'-UTR,CDS3.187008.76150HepG2LARP4
chr166658650066586573+5'-UTR4.7814729.90724HepG2DDX3X
chr166658653266586632+5'-UTR,CDS3.9405812.06609HepG2NCBP2
chr166658652966586652+5'-UTR,CDS3.476948.36924K562FTO
chr166658657366586633+5'-UTR,CDS4.8181821.60578HepG2DDX3X
chr166659219566592248+CDS,intron-Distal4.172893.66655K562YBX3
chr166659215166592195+CDS,intron-Distal3.849043.02250K562YBX3
chr166659978966599885+CDS,intron-Distal3.260788.24214HepG2LARP4
chr166659978866599896+CDS,intron-Distal,intron-Proximal4.298363.67607K562YBX3
chr166659838466598442+intron-Distal3.831667.38558HepG2HNRNPC
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CKLF is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CKLF is not available on ENCORE database.

  • 66 RBPs can affect the levels of CKLF.  








The Knockdown/knockout RNA-Seq assay for CKLF is not available on ENCORE database.





66 RBPs can affect the gene expression of CKLF :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CKLFENSG00000217555.81183.87330708.805100.740006.615705.83250HepG2AKAP1
CKLFENSG00000217555.8366.77700528.45700-0.526905.350404.48170HepG2CKAP4
CKLFENSG00000217555.8311.87600407.31440-0.385202.248501.33310HepG2YBX3
CKLFENSG00000217555.8294.80030432.57380-0.553203.677802.90460HepG2DDX21
CKLFENSG00000217555.8961.13870583.334500.720306.169405.27530HepG2DDX6
CKLFENSG00000217555.8374.68530505.70450-0.432603.303002.57220HepG2DKC1
CKLFENSG00000217555.8277.03450408.35920-0.559803.975302.70650HepG2EIF3G
CKLFENSG00000217555.8421.25400603.31190-0.518202.565301.90080HepG2EIF4B
CKLFENSG00000217555.8518.67230701.77660-0.436202.765301.95010HepG2EIF4G2
CKLFENSG00000217555.8190.49620395.21380-1.0529010.108908.65160HepG2FUBP3
CKLFENSG00000217555.8429.66220615.78400-0.519203.429402.43080HepG2G3BP2
CKLFENSG00000217555.8182.94950272.19710-0.573202.394101.79490HepG2GPKOW
CKLFENSG00000217555.8151.07920403.81230-1.4184015.0043013.69250HepG2HNRNPA1
CKLFENSG00000217555.8302.92240449.15270-0.568303.602902.81950HepG2HNRNPC
CKLFENSG00000217555.8822.81530676.312700.282802.869802.18550HepG2HNRNPL
CKLFENSG00000217555.8264.65400446.18420-0.753508.277807.27040HepG2HNRNPU
CKLFENSG00000217555.8430.59340589.45000-0.453002.626001.96610HepG2IGF2BP2
CKLFENSG00000217555.8319.86840458.47050-0.519403.502002.12740HepG2LIN28B
CKLFENSG00000217555.8458.06600643.74020-0.490903.033302.37160HepG2NCBP2
CKLFENSG00000217555.8177.27160402.74890-1.183906.572604.86310HepG2NONO
CKLFENSG00000217555.8415.78530573.18820-0.463202.730202.01310HepG2PABPC4
CKLFENSG00000217555.8461.41510633.51040-0.457304.336603.60630HepG2PCBP1
CKLFENSG00000217555.8328.20710504.37900-0.619903.296502.16600HepG2PCBP2
CKLFENSG00000217555.8314.02140397.96310-0.341801.956501.32840HepG2PPIL4
CKLFENSG00000217555.8185.36870338.40740-0.868405.321404.23760HepG2PRPF8
CKLFENSG00000217555.8416.61360644.63210-0.629807.351506.54440HepG2PTBP1
CKLFENSG00000217555.8399.03920702.85280-0.816708.904507.91740HepG2PUF60
CKLFENSG00000217555.8720.15750486.693100.565202.504301.83230HepG2RAVER1
CKLFENSG00000217555.8699.23360484.426900.529404.935303.83040HepG2RBM15
CKLFENSG00000217555.8392.46380633.60520-0.691006.749305.73730HepG2RBM25
CKLFENSG00000217555.8485.94070717.40400-0.562003.646003.04190HepG2NELFE
CKLFENSG00000217555.8442.55110668.18180-0.594406.544705.65420HepG2RECQL
CKLFENSG00000217555.8158.28860272.80080-0.785304.868804.07930HepG2RPS19
CKLFENSG00000217555.8320.33290485.71280-0.600504.350703.35730HepG2RPS2
CKLFENSG00000217555.8304.59580473.39120-0.636103.537902.63260HepG2RPS3A
CKLFENSG00000217555.8292.19290405.70630-0.473502.000101.42500HepG2SF3A3
CKLFENSG00000217555.8373.33440671.12450-0.8461011.8465010.75740HepG2SF3B4
CKLFENSG00000217555.8548.35810674.00560-0.297602.181401.54600HepG2SLBP
CKLFENSG00000217555.8336.46370463.39670-0.461803.945303.19930HepG2SMN1
CKLFENSG00000217555.8861.54900704.310200.290602.473801.99050HepG2SRFBP1
CKLFENSG00000217555.8492.37110700.51710-0.508705.228104.63100HepG2SRSF1
CKLFENSG00000217555.8553.59980694.01110-0.326102.337701.75640HepG2SRSF5
CKLFENSG00000217555.8676.77640569.915300.247801.792501.33100HepG2SRSF9
CKLFENSG00000217555.8480.32940611.51150-0.348402.727802.21750HepG2SSB
CKLFENSG00000217555.8630.53700789.24210-0.323902.772802.15040HepG2SUCLG1
CKLFENSG00000217555.8470.29110629.67560-0.421103.237102.63750HepG2TAF15
CKLFENSG00000217555.8176.10780253.19160-0.523802.244301.58170HepG2TARDBP
CKLFENSG00000217555.8254.28330433.60320-0.769907.032806.30280HepG2TIAL1
CKLFENSG00000217555.8343.85840437.42360-0.347202.295401.77190HepG2TRIM56
CKLFENSG00000217555.8345.57690257.958600.421802.039801.38800HepG2UCHL5
CKLFENSG00000217555.8252.57110359.79990-0.510503.665102.87880HepG2UPF1
CKLFENSG00000217555.8490.93260347.372000.498903.927703.23270HepG2UTP3
CKLFENSG00000217555.8311.31490535.27690-0.781905.113703.70140HepG2XRCC6
CKLFENSG00000217555.8470.21260311.822800.592505.743504.83040HepG2ZC3H8
CKLFENSG00000217555.8318.41420486.32690-0.611003.429601.97830HepG2ZRANB2
CKLFENSG00000217555.8225.26610552.13770-1.2934014.5247013.32820K562AQR
CKLFENSG00000217555.8551.69690837.49690-0.602206.127104.68380K562CELF1
CKLFENSG00000217555.8731.41220357.349101.0333017.7617016.17090K562EIF2S2
CKLFENSG00000217555.8346.67020246.290600.493102.716701.87620K562FIP1L1
CKLFENSG00000217555.8166.00170287.16340-0.790703.768302.91420K562G3BP2
CKLFENSG00000217555.8276.32240427.87620-0.630804.860803.45090K562HNRNPA1
CKLFENSG00000217555.8145.03820207.48740-0.516601.973501.45790K562HNRNPC
CKLFENSG00000217555.8455.18700329.882200.464403.012601.90550K562HNRNPL
CKLFENSG00000217555.8339.73650202.609600.745604.513903.30340K562HNRNPM
CKLFENSG00000217555.8282.96200473.88290-0.743904.596603.44010K562HNRNPU
CKLFENSG00000217555.8541.45560333.872900.697405.734404.60490K562HSPD1
CKLFENSG00000217555.8227.86190361.09850-0.664203.861802.88010K562PCBP3
CKLFENSG00000217555.8181.89810276.97770-0.606603.579002.66190K562POLR2G
CKLFENSG00000217555.8436.48630279.634800.642304.400203.33300K562PPIG
CKLFENSG00000217555.8514.33650743.23750-0.531103.925402.95760K562PUF60
CKLFENSG00000217555.8295.57380409.94980-0.471902.816601.96880K562RBM22
CKLFENSG00000217555.8161.58730298.36990-0.884807.225905.80340K562SF3B4
CKLFENSG00000217555.8219.02530315.27100-0.525503.086201.48150K562SRSF9
CKLFENSG00000217555.8224.04540309.49290-0.466102.856301.99590K562WDR43
CKLFENSG00000217555.8433.78760621.99810-0.519904.127303.03680K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CKLF is not available on ENCORE database.





25 RBPs can affect the splicing of CKLF :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.127000.000000.00015includedHepG2G3BP1
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.225000.000000.00000includedK562SRSF1
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.097000.000090.00912includedHepG2RBM22
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.233000.000000.00000excludedHepG2U2AF1
SECKLFENSG00000217555.8chr16+665970246659712066586471665866966659978866599972-0.109000.000130.01736excludedHepG2PRPF8
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.142000.000010.00638excludedHepG2DKC1
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.300000.000000.00000excludedHepG2HNRNPK
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.146000.000630.00956excludedHepG2U2AF2
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.117000.000000.00002includedHepG2AKAP1
SECKLFENSG00000217555.8chr16+6659702466597120665864716658669666599788665999720.058000.000410.07320includedK562APOBEC3C
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.134000.000000.00013includedHepG2MATR3
SECKLFENSG00000217555.8chr16+665920926659225166586484665866966659702466597120-0.180000.000130.00857excludedHepG2MATR3
SECKLFENSG00000217555.8chr16+6659209266592251665864846658669666597024665971200.170000.001100.02434includedK562U2AF1
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.280000.000000.00000excludedK562U2AF1
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.087000.000460.01351includedHepG2SRSF1
SECKLFENSG00000217555.8chr16+665920926659225166586484665866966659702466597120-0.153000.000820.02178excludedHepG2SRSF1
SECKLFENSG00000217555.8chr16+665920926659225166586484665866966659978866599975-0.124000.000790.05711excludedHepG2TIAL1
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.241000.000000.00003excludedK562U2AF2
SECKLFENSG00000217555.8chr16+6659209266592251665864846658669666597024665971200.211000.000010.00094includedK562TARDBP
SECKLFENSG00000217555.8chr16+665970246659712066586471665866966659978866599972-0.103000.000100.00601excludedK562TARDBP
SECKLFENSG00000217555.8chr16+665970246659712066586471665866966659978866599972-0.099000.002840.08301excludedK562HNRNPU
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.206000.000840.02399excludedK562RBM15
SECKLFENSG00000217555.8chr16+6659209266592251665864846658669666597024665971200.138000.000400.07170includedHepG2DDX55
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.278000.001940.06683excludedK562SF3B1
SECKLFENSG00000217555.8chr16+6659209266592251665864846658669666597024665971200.275000.000000.00000includedK562HNRNPK
SECKLFENSG00000217555.8chr16+665970246659712066592092665922516659978866599972-0.338000.000000.00006excludedK562HNRNPK
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.116000.000000.00045includedHepG2HNRNPC
SECKLFENSG00000217555.8chr16+665970056659712066592092665922516659978866599975-0.182000.000200.08782excludedHepG2SLTM
SECKLFENSG00000217555.8chr16+6659702466597120665920926659225166599788665999720.316000.000000.00000includedK562HNRNPC
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.155000.000080.078281includedK562DDX24
MXECKLFENSG00000217555.8chr16+66592135665922516659700566597120665864656658669666599788665999750.197000.000000.000011includedHepG2U2AF1
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.152000.000040.020262includedHepG2EIF3H
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.131000.000070.003322includedHepG2MATR3
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.207000.000370.052921includedHepG2RBM5
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.175000.000000.000002includedHepG2SRSF1
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.211000.000000.000011includedK562U2AF1
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.101000.001590.027152includedK562SRSF1
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.188000.000000.001842includedHepG2NKRF
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.185000.000010.001531includedK562SF3B1
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.103000.015340.089121includedK562AQR
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.150000.000170.003771includedK562U2AF2
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.144000.000110.004661includedK562TARDBP
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.098000.004910.080951includedHepG2DDX55
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.168000.000060.006401includedK562SAFB
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.139000.002450.080451includedK562HNRNPU
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.201000.000000.000001includedHepG2HNRNPK
MXECKLFENSG00000217555.8chr16+6659209266592251665970246659712066586471665866966659978866599975-0.198000.000000.000022includedHepG2TIAL1
MXECKLFENSG00000217555.8chr16+66592092665922516659702466597120665864716658669666599788665999750.333000.000000.000001includedK562HNRNPK

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CKLF is not avaliable on ENCORE database.