VPS16

General Information

Gene Name       : VPS16
Gene ID             : ENSG00000215305.9
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: VPS16)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878VPS16ENSG00000215305.95.9912.319.15ENCSR000AEF
HepG2VPS16ENSG00000215305.930.2922.1626.23ENCSR985KAT
K562VPS16ENSG00000215305.911.099.4310.26ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for VPS16 is not avaliable on ENCORE database.



Proteins bound to RNA
  • VPS16 RNA is bound by 8 proteins.  







eCLIP assay for VPS16 is not avaliable on ENCORE database.





8 proteins are bound to VPS16 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2028404012840452+3'-UTR,CDS3.455788.57574HepG2PPIG
chr2028412102841235+CDS3.692755.24452HepG2PPIG
chr2028433892843481+CDS,intron-Distal,intron-Proximal4.014088.17769HepG2PRPF4
chr2028452362845300+5'-UTR,CDS3.441904.88837HepG2PABPN1
chr2028469032846962+CDS,intron-Distal,intron-Proximal4.190773.80435HepG2LSM11
chr2028447112844768+CDS,intron-Proximal4.870989.43475HepG2PRPF8
chr2028432372843297+CDS,intron-Distal,intron-Proximal4.4761110.14097HepG2PPIG
chr2028456222845686+5'-UTR,CDS,intron-Proximal3.634825.38978HepG2PABPN1
chr2028427182842740+CDS,intron-Distal,intron-Proximal3.818434.24993HepG2PPIG
chr2028427402842767+CDS,intron-Distal,intron-Proximal4.510906.08299HepG2PPIG
chr2028433962843461+CDS,intron-Distal,intron-Proximal4.344744.77050HepG2SF3B4
chr2028425072842545+CDS,intron-Distal3.824265.86107HepG2PPIG
chr2028460932846150+CDS,intron-Distal,intron-Proximal4.009053.33617HepG2PABPN1
chr2028425182842603+CDS,intron-Distal,intron-Proximal5.446389.61125HepG2PRPF8
chr2028449182844929+5'-UTR,CDS4.517934.97342HepG2PPIG
chr2028461402846251+CDS,intron-Distal,intron-Proximal4.162634.89208K562AQR
chr2028406992840721+CDS,intron-Distal,intron-Proximal3.438946.13978HepG2PPIG
chr2028449922845040+5'-UTR,CDS,intron-Proximal4.070135.30739HepG2BUD13
chr2028459042845950+5'-UTR,CDS3.225533.28107HepG2PABPN1
chr2028449762845057+5'-UTR,CDS,intron-Proximal3.957163.18234K562BUD13
chr2028470732847159+CDS,intron-Distal,intron-Proximal3.749934.52386HepG2PABPN1
chr2028469122846962+CDS,intron-Distal,intron-Proximal4.389807.79455HepG2PPIG
chr2028468562846962+CDS,intron-Distal,intron-Proximal5.7340711.13583HepG2PABPN1
chr2028409972841002+CDS,intron-Proximal3.474703.59112HepG2PPIG
chr2028471072847157+CDS,intron-Distal3.217413.34848HepG2PPIG
chr2028461882846233+intron-Distal,intron-Proximal4.285724.27476HepG2AQR
chr2028447462844809+intron-Proximal3.914713.25678HepG2SF3B4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for VPS16 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for VPS16 is not available on ENCORE database.

  • 61 RBPs can affect the levels of VPS16.  








The Knockdown/knockout RNA-Seq assay for VPS16 is not available on ENCORE database.





61 RBPs can affect the gene expression of VPS16 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
VPS16ENSG00000215305.5994.81600810.000000.296403.048002.41470HepG2ACO1
VPS16ENSG00000215305.52053.058801017.819301.0122013.5517012.46630HepG2AKAP1
VPS16ENSG00000215305.51085.72850842.163300.366402.383301.65060HepG2ASCC1
VPS16ENSG00000215305.51312.204901013.888400.372004.820403.95560HepG2AUH
VPS16ENSG00000215305.5892.60670675.044200.402902.413501.53980HepG2BCCIP
VPS16ENSG00000215305.5679.81260479.766200.502703.787203.09850HepG2BOP1
VPS16ENSG00000215305.51297.84520800.112100.697707.745706.50280HepG2CIRBP
VPS16ENSG00000215305.5968.34540809.830900.257802.492101.85420HepG2CKAP4
VPS16ENSG00000215305.5658.45700440.449700.580004.361203.51470HepG2CPSF6
VPS16ENSG00000215305.5648.42600510.462800.345002.610501.62330HepG2YBX3
VPS16ENSG00000215305.51173.59220879.681300.415805.101904.27700HepG2CELF1
VPS16ENSG00000215305.51268.02510945.865400.422806.792705.70710HepG2DAZAP1
VPS16ENSG00000215305.5857.53050581.795900.559605.147204.24930HepG2DDX21
VPS16ENSG00000215305.51244.03360975.001000.351402.254301.68440HepG2DDX3X
VPS16ENSG00000215305.5898.74470663.692600.437302.767601.99440HepG2DDX55
VPS16ENSG00000215305.5594.73810429.706500.468802.864501.73760HepG2EFTUD2
VPS16ENSG00000215305.51024.98700805.153900.348202.138401.60980HepG2EIF2S1
VPS16ENSG00000215305.51515.04150889.797700.767708.079906.99120HepG2EIF4A3
VPS16ENSG00000215305.51378.419101164.115300.243702.169301.62480HepG2ETF1
VPS16ENSG00000215305.5507.55840374.124800.440002.997101.77400HepG2FAM120A
VPS16ENSG00000215305.51159.66020897.744200.369202.454801.80190HepG2FXR1
VPS16ENSG00000215305.51077.13830832.802200.371102.303701.69380HepG2G3BP1
VPS16ENSG00000215305.5673.82470506.014900.413102.450901.84040HepG2HNRNPA1
VPS16ENSG00000215305.51039.77370869.281200.258302.202001.35840HepG2HNRNPA2B1
VPS16ENSG00000215305.5765.17010562.859400.442903.178002.44140HepG2HNRNPC
VPS16ENSG00000215305.5912.36930768.619500.247202.174601.53360HepG2HNRNPF
VPS16ENSG00000215305.51055.34290861.608600.292503.231602.50790HepG2HNRNPL
VPS16ENSG00000215305.5619.33900476.471600.378202.051601.50090HepG2HNRNPLL
VPS16ENSG00000215305.51179.92780846.529800.479003.002702.30390HepG2IGF2BP2
VPS16ENSG00000215305.5750.34970571.138200.393604.476503.56250HepG2ILF2
VPS16ENSG00000215305.5771.18750525.575600.553104.337003.33650HepG2MSI2
VPS16ENSG00000215305.51211.96600937.918700.369703.339802.50360HepG2NOL12
VPS16ENSG00000215305.5777.68830512.072900.602704.923803.88010HepG2PRPF8
VPS16ENSG00000215305.51158.92120950.432300.286003.547802.89340HepG2PUM1
VPS16ENSG00000215305.5595.29560856.29610-0.524505.023804.13940HepG2RBM25
VPS16ENSG00000215305.5550.30650407.248200.434202.672502.06730HepG2RPS19
VPS16ENSG00000215305.5679.64970506.554700.424002.487901.73950HepG2RRP9
VPS16ENSG00000215305.5701.36630580.659000.272402.258701.66820HepG2SMN1
VPS16ENSG00000215305.51129.02370884.008600.352804.037603.30730HepG2SRSF5
VPS16ENSG00000215305.51147.22320954.107700.265802.626802.12240HepG2SSB
VPS16ENSG00000215305.51276.648101005.358700.344604.454903.70090HepG2SUCLG1
VPS16ENSG00000215305.5612.63080850.94810-0.474104.872804.16170HepG2TAF15
VPS16ENSG00000215305.5781.70200543.263900.524905.291104.64520HepG2TIAL1
VPS16ENSG00000215305.5682.01270548.165800.315102.650502.09540HepG2TRIM56
VPS16ENSG00000215305.5518.20800390.325700.408802.402901.69500HepG2UCHL5
VPS16ENSG00000215305.5809.74130605.085300.420202.197401.30840HepG2UPF2
VPS16ENSG00000215305.5523.52100417.821500.325302.330801.70700HepG2ZC3H8
VPS16ENSG00000215305.51206.66100800.111200.5926012.3317011.38410HepG2ZNF622
VPS16ENSG00000215305.5557.31010377.285400.562702.542101.53140K562CNOT7
VPS16ENSG00000215305.5629.22890482.750700.382203.266102.56730K562DDX47
VPS16ENSG00000215305.5655.63370518.413400.338702.615601.91180K562EIF2S2
VPS16ENSG00000215305.5309.51390199.335600.634704.023703.07360K562EIF3G
VPS16ENSG00000215305.554.35960161.87810-1.574308.511907.12790K562G3BP2
VPS16ENSG00000215305.5264.02220170.069200.634402.387001.64690K562GPKOW
VPS16ENSG00000215305.5966.86920690.869500.484804.300403.36170K562GRSF1
VPS16ENSG00000215305.5432.09870319.611500.434902.791602.12430K562PTBP1
VPS16ENSG00000215305.5436.18910322.451300.435802.414301.40680K562NELFE
VPS16ENSG00000215305.5241.10920168.243100.519002.541501.72360K562SF3B4
VPS16ENSG00000215305.5491.25340317.089300.631504.631203.70980K562TARDBP
VPS16ENSG00000215305.5446.97230305.876800.547103.881202.88940K562TIA1
VPS16ENSG00000215305.5414.19500300.231100.464102.536801.50080K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for VPS16 is not available on ENCORE database.





6 RBPs can affect the splicing of VPS16 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RIVPS16ENSG00000215305.5chr20+284459428449332844594284472928448242844933-0.059000.000270.01729excludedHepG2AKAP1
RIVPS16ENSG00000215305.5chr20+284459428449332844594284472928448242844933-0.091000.001080.08279excludedK562NSUN2
RIVPS16ENSG00000215305.5chr20+284459428449332844594284472928448242844933-0.113000.000000.00004excludedK562UPF1
RIVPS16ENSG00000215305.5chr20+2844594284493328445942844729284482428449330.112000.001610.01776includedHepG2TAF15
RIVPS16ENSG00000215305.5chr20+2844594284493328445942844729284482428449330.083000.000230.08400includedHepG2IGF2BP1
RIVPS16ENSG00000215305.5chr20+2844594284493328445942844729284482428449330.238000.001010.00678includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for VPS16 is not avaliable on ENCORE database.