TPCN2

General Information

Gene Name       : TPCN2
Gene ID             : ENSG00000162341.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TPCN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TPCN2ENSG00000162341.163.915.684.79ENCSR000AEF
HepG2TPCN2ENSG00000162341.164.993.184.08ENCSR985KAT
K562TPCN2ENSG00000162341.164.143.393.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TPCN2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TPCN2 RNA is bound by 27 proteins.  







eCLIP assay for TPCN2 is not avaliable on ENCORE database.





27 proteins are bound to TPCN2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr116881640368816487+5'-UTR,CDS4.773875.85636HepG2NCBP2
chr116882153868821618+CDS,intron-Proximal4.156486.95612HepG2PRPF8
chr116883140668831467+CDS,intron-Proximal4.173686.64430HepG2PPIG
chr116883136268831381+CDS,intron-Proximal3.545373.05161HepG2PPIG
chr116885407168854148+CDS,intron-Distal,intron-Proximal3.870683.57432K562NONO
chr116885261968852692+CDS,intron-Distal,intron-Proximal4.701535.81141K562CSTF2T
chr116883792068837965+CDS,intron-Proximal3.727944.68902HepG2PPIG
chr116883142868831510+CDS,intron-Proximal3.392586.83379HepG2CSTF2T
chr116884639968846455+CDS3.848783.56019HepG2GRWD1
chr116884620168846261+CDS,intron-Proximal3.277625.54641HepG2PPIG
chr116883882568838892+CDS,intron-Proximal3.227943.66193HepG2PPIG
chr116884604368846061+CDS4.173684.08604HepG2PPIG
chr116883038968830459+CDS,intron-Proximal5.0860412.29445HepG2PPIG
chr116883264268832706+intron-Distal3.472848.75909HepG2CSTF2T
chr116885159768851651+intron-Distal4.176827.48189HepG2CSTF2T
chr116883262868832715+intron-Distal7.7716244.05847K562EIF4G2
chr116883197068832013+intron-Distal4.9694511.45661K562EIF4G2
chr116884426668844325+intron-Distal5.477968.60433HepG2DDX59
chr116884841468848522+intron-Distal5.5109110.10424HepG2CSTF2T
chr116884446368844534+intron-Distal4.094787.74636HepG2HNRNPK
chr116883179368831907+intron-Distal5.6835431.87206HepG2DDX59
chr116883530168835341+intron-Distal4.375786.57428HepG2PTBP1
chr116884984468849915+intron-Distal3.792528.35041HepG2HNRNPL
chr116883427068834312+intron-Distal3.029603.25653K562CSTF2T
chr116883344368833540+intron-Distal4.055896.08336HepG2NKRF
chr116883244468832681+intron-Distal5.7750215.10225K562TARDBP
chr116883333168833382+intron-Distal4.721404.28089HepG2FAM120A
chr116885129068851360+intron-Distal,intron-Proximal4.529605.60464K562CSTF2T
chr116883012668830177+intron-Distal4.040313.94684HepG2CSTF2T
chr116883333368833395+intron-Distal4.977387.23521HepG2HNRNPM
chr116884426468844361+intron-Distal4.8467614.31206HepG2HNRNPK
chr116885214468852209+intron-Distal3.123643.91530HepG2PRPF4
chr116883363868833732+intron-Distal4.592836.06839HepG2PRPF4
chr116884436168844424+intron-Distal5.349599.77805HepG2HNRNPK
chr116883450168834543+intron-Distal3.095404.88713HepG2CSTF2T
chr116883536968835389+intron-Distal4.072926.57428HepG2PTBP1
chr116884976668849800+intron-Distal3.281716.24785HepG2HNRNPL
chr116883526368835394+intron-Distal4.4446312.14628K562PTBP1
chr116885118068851325+intron-Distal,intron-Proximal5.323918.82769HepG2PRPF4
chr116884428068844349+intron-Distal3.141623.04847HepG2CSTF2T
chr116885150768851594+intron-Distal,intron-Proximal4.666955.55667K562EWSR1
chr116885133568851387+intron-Distal,intron-Proximal3.892735.08839HepG2CSTF2T
chr116883196968832022+intron-Distal4.252163.53896K562NONO
chr116884918768849273+intron-Distal4.132123.08079HepG2AGGF1
chr116883329668833370+intron-Distal4.727316.58779K562EWSR1
chr116883346168833529+intron-Distal4.780776.58779K562EWSR1
chr116884972168849835+intron-Distal3.322054.95846K562HNRNPL
chr116884842468848506+intron-Distal3.505693.57490HepG2NKRF
chr116885117468851333+intron-Distal,intron-Proximal4.630926.67181HepG2IGF2BP1
chr116884465668844701+intron-Distal4.452545.62745HepG2HNRNPK
chr116883217168832233+intron-Distal6.195386.08563HepG2DKC1
chr116883330168833383+intron-Distal3.7115112.14979HepG2CSTF2T
chr116883178868831843+intron-Distal4.715193.11886K562DROSHA
chr116883264168832696+intron-Distal4.457734.75311K562CSTF2T
chr116883216368832224+intron-Distal3.283673.77567K562NONO
chr116883366868833736+intron-Distal4.612224.72743K562NONO
chr116885151468851566+intron-Distal,intron-Proximal4.052377.23771HepG2CSTF2T
chr116884841968848501+intron-Distal3.802543.52528HepG2FAM120A
chr116884432568844404+intron-Distal4.8706311.56694HepG2DDX59
chr116885468168854786+intron-Distal,intron-Proximal3.264913.36199K562EWSR1
chr116885129568851379+intron-Distal,intron-Proximal4.626494.98766K562EWSR1
chr116883811468838234+intron-Distal3.526764.34707HepG2HNRNPK
chr116883486468834964+intron-Distal,intron-Proximal3.430996.57490HepG2CSTF2T
chr116883211568832164+intron-Distal4.823508.44255K562EIF4G2
chr116884844068848514+intron-Distal4.420135.28165K562CSTF2T
chr116883217468832240+intron-Distal4.516355.81141K562CSTF2T
chr116883330168833429+intron-Distal5.6946318.73721K562EIF4G2
chr116883218168832237+intron-Distal5.0944412.15393K562EIF4G2
chr116883347268833570+intron-Distal4.317925.23978HepG2PRPF4
chr116884427468844351+intron-Distal6.1121014.07031HepG2PCBP2
chr116883426668834342+intron-Distal3.373155.66356HepG2CSTF2T
chr116884484668844889+intron-Distal5.312897.43360HepG2DDX59
chr116884979368849914+intron-Distal6.5436917.55005K562AGGF1
chr116883347368833533+intron-Distal5.0094810.02297K562EIF4G2
chr116883293368832998+intron-Distal3.526144.61500HepG2HNRNPM
chr116885150168851561+intron-Distal,intron-Proximal3.110413.29499HepG2PRPF4
chr116883218368832240+intron-Distal3.375206.58651HepG2CSTF2T
chr116883330768833368+intron-Distal4.238153.70058K562CSTF2T
chr116884840568848494+intron-Distal4.952778.29787HepG2PRPF4
chr116884459668844684+intron-Distal5.9154313.54105HepG2PCBP2
chr116883371968833755+intron-Distal4.595406.05659HepG2CSTF2T
chr116883227268832410+intron-Distal4.951306.75032K562TARDBP
chr116883365468833725+intron-Distal4.108487.26345HepG2NKRF
chr116883175068831797+intron-Distal4.224633.23894HepG2PCBP2
chr116883365168833741+intron-Distal4.7249310.29014HepG2FAM120A
chr116885290068852921+intron-Distal3.247833.69530HepG2CSTF2T
chr116884943368849499+intron-Distal3.803933.07008K562NONO
chr116885214268852186+intron-Distal4.239274.16830K562EWSR1
chr116884484468844874+intron-Distal3.683405.12778HepG2PCBP2
chr116883347268833534+intron-Distal3.195487.61507HepG2CSTF2T
chr116883346768833543+intron-Distal5.6752513.21421HepG2FAM120A
chr116885132568851373+intron-Distal,intron-Proximal3.969213.15816HepG2PRPF4
chr116883205768832115+intron-Distal4.2226110.48436K562EIF4G2
chr116883178868831889+intron-Distal4.404104.76505K562HNRNPK
chr116883534168835369+intron-Distal4.020537.62792HepG2PTBP1
chr116884921168849282+intron-Distal4.102383.53896K562NONO
chr116883263768832696+intron-Distal4.323284.43116HepG2RBFOX2
chr116884445868844521+intron-Distal5.089164.91906HepG2DDX59
chr116883366168833708+intron-Distal3.894177.39148K562EIF4G2
chr116883330068833331+intron-Distal4.235413.41584HepG2FAM120A
chr116883525468835301+intron-Distal4.685244.40847HepG2PTBP1
chr116883331268833367+intron-Distal3.790063.55896HepG2STAU2
chr116883167768831727+intron-Distal3.895156.14899HepG2PCBP2
chr116884457068844630+intron-Distal3.997316.29348HepG2HNRNPK
chr116883262668832687+intron-Distal4.008813.35850HepG2TIAL1
chr116885261968852677+intron-Distal,intron-Proximal3.9806610.06144HepG2CSTF2T
chr116883211868832186+intron-Distal4.040153.60235HepG2HNRNPM
chr116885193868851981+intron-Distal3.088746.35020HepG2CSTF2T
chr116884437268844425+intron-Distal5.422477.89532HepG2PCBP2
chr116883365768833719+intron-Distal5.335645.60708K562DDX52
chr116885214568852207+intron-Distal3.332797.23670HepG2CSTF2T
chr116883349468833551+intron-Distal4.335214.48497K562NONO
chr116884983768849900+intron-Distal4.520664.97583HepG2GTF2F1
chr116883293368832993+intron-Distal3.313743.25653K562CSTF2T
chr116884864168848699+intron-Distal4.551676.05659HepG2CSTF2T
chr116883449468834551+intron-Distal4.567295.01722K562CSTF2T
chr116885367368853706+intron-Distal3.651514.35339HepG2CSTF2T
chr116883396268834011+intron-Distal4.509613.87340HepG2CSTF2T
chr116884983568849918+intron-Distal4.727687.69118K562HNRNPL
chr116885199168852029+intron-Distal3.629084.84557HepG2CSTF2T
chr116885246668852516+intron-Distal3.832796.26465HepG2CSTF2T
chr116884968668849766+intron-Distal3.535784.47941HepG2HNRNPL
chr116883365068833719+intron-Distal3.098868.24586HepG2CSTF2T
chr116884801668848052+intron-Distal3.908793.63902HepG2CSTF2T
chr116883259668832727+intron-Distal6.2172110.69076HepG2DKC1
chr116883049768830540+intron-Proximal3.760603.19526HepG2CSTF2T
chr116885471368854773+intron-Proximal3.456153.46580HepG2CSTF2T
chr116883487368834947+intron-Proximal3.832473.39593HepG2PRPF4
chr116883145668831530+intron-Proximal4.319313.80314K562CSTF2T
chr116883487568834952+intron-Proximal4.349393.56427K562FAM120A
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TPCN2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TPCN2 is not available on ENCORE database.

  • 44 RBPs can affect the levels of TPCN2.  








The Knockdown/knockout RNA-Seq assay for TPCN2 is not available on ENCORE database.





44 RBPs can affect the gene expression of TPCN2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TPCN2ENSG00000162341.11163.2322083.191300.972303.519902.65070HepG2CNOT7
TPCN2ENSG00000162341.11331.38920192.244200.785504.568403.75050HepG2EIF4A3
TPCN2ENSG00000162341.11294.47900191.162000.623303.060602.12380HepG2G3BP2
TPCN2ENSG00000162341.11275.20180194.161100.503102.053901.48520HepG2MAGOH
TPCN2ENSG00000162341.11269.39480202.943800.408502.054801.50540HepG2PUS1
TPCN2ENSG00000162341.1172.11490135.62860-0.911302.557901.87940HepG2RAVER1
TPCN2ENSG00000162341.11169.4768083.579401.019804.366303.36000HepG2RPS3A
TPCN2ENSG00000162341.11189.86770340.11480-0.841007.152406.45030HepG2SRFBP1
TPCN2ENSG00000162341.11155.45280235.73140-0.600703.214402.61060K562AGGF1
TPCN2ENSG00000162341.11158.78010245.27950-0.627403.302402.58710K562AKAP8L
TPCN2ENSG00000162341.11133.72150355.33080-1.4099011.5929010.51260K562AQR
TPCN2ENSG00000162341.11189.63360257.33890-0.440502.293401.46940K562ATP5C1
TPCN2ENSG00000162341.1188.64810170.89180-0.946904.113603.04720K562BOP1
TPCN2ENSG00000162341.11113.62600181.71090-0.677402.939002.13080K562CPSF6
TPCN2ENSG00000162341.11408.36000523.70550-0.358902.308401.41810K562CELF1
TPCN2ENSG00000162341.11148.33560255.68250-0.785505.424604.55640K562DDX47
TPCN2ENSG00000162341.11127.39060210.52140-0.724703.203301.81600K562EEF2
TPCN2ENSG00000162341.11133.98960203.37980-0.602102.573701.69660K562EFTUD2
TPCN2ENSG00000162341.11126.21400217.71540-0.786603.651202.44730K562EIF3D
TPCN2ENSG00000162341.11120.95940184.87900-0.612102.389501.59330K562FMR1
TPCN2ENSG00000162341.1195.57370156.69840-0.713302.644401.75140K562FTO
TPCN2ENSG00000162341.1151.96350103.18910-0.989703.011002.26820K562G3BP2
TPCN2ENSG00000162341.1198.93170173.49220-0.810403.467602.58180K562GPKOW
TPCN2ENSG00000162341.1174.80790199.21140-1.413003.705602.22440K562HNRNPA2B1
TPCN2ENSG00000162341.1177.70580184.05530-1.244006.891205.98840K562HNRNPC
TPCN2ENSG00000162341.11152.88390260.33700-0.767904.642103.52640K562KIF1C
TPCN2ENSG00000162341.1182.02200148.13270-0.852802.787901.85100K562KRR1
TPCN2ENSG00000162341.11171.29570249.17890-0.540702.374501.40460K562MAK16
TPCN2ENSG00000162341.11107.81740169.34650-0.651402.521601.68930K562METAP2
TPCN2ENSG00000162341.11111.03320204.41440-0.880503.670902.62040K562NAA15
TPCN2ENSG00000162341.11334.66670465.83760-0.477102.897901.37220K562NOL12
TPCN2ENSG00000162341.11210.57290278.49070-0.403302.079901.42240K562NSUN2
TPCN2ENSG00000162341.1170.60390174.37770-1.304403.399502.26900K562PABPN1
TPCN2ENSG00000162341.1180.11000197.91300-1.304807.434506.20680K562PRPF8
TPCN2ENSG00000162341.11255.01350464.61200-0.865507.351506.01900K562PUF60
TPCN2ENSG00000162341.11110.31030243.31960-1.141306.951506.13600K562PUS1
TPCN2ENSG00000162341.11122.82130237.02060-0.948506.305705.43560K562RBM15
TPCN2ENSG00000162341.11115.25950202.32420-0.811803.307201.85370K562RRP9
TPCN2ENSG00000162341.1190.67800164.98610-0.863503.318802.25170K562SF3B1
TPCN2ENSG00000162341.1181.69350183.11570-1.164503.003001.70470K562SNRNP200
TPCN2ENSG00000162341.11119.72750191.56720-0.678102.703501.69850K562SUPV3L1
TPCN2ENSG00000162341.11249.09790168.148600.566902.860202.02600K562TIA1
TPCN2ENSG00000162341.11134.82280246.63030-0.871303.000201.63430K562UTP18
TPCN2ENSG00000162341.11183.53720252.66920-0.461202.072701.31660K562WDR3
TPCN2ENSG00000162341.11171.20800262.75860-0.618003.883302.89210K562WDR43
TPCN2ENSG00000162341.11298.30150400.31320-0.424402.412701.61600K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TPCN2 is not available on ENCORE database.





1 RBPs can affect the splicing of TPCN2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETPCN2ENSG00000162341.11chr11+688349706883507368831362688314356883789768837963-0.364000.003400.09462excludedK562HNRNPU

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TPCN2 is not avaliable on ENCORE database.