SPAG1

General Information

Gene Name       : SPAG1
Gene ID             : ENSG00000104450.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: SPAG1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPAG1ENSG00000104450.1214.219.7511.98ENCSR000AEF
HepG2SPAG1ENSG00000104450.121.893.192.54ENCSR985KAT
K562SPAG1ENSG00000104450.120.610.430.52ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPAG1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPAG1 RNA is bound by 1 proteins.  







eCLIP assay for SPAG1 is not avaliable on ENCORE database.





1 proteins are bound to SPAG1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8101197390101197473+intron-Distal4.114673.04630K562TROVE2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPAG1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPAG1 is not available on ENCORE database.

  • 57 RBPs can affect the levels of SPAG1.  








The Knockdown/knockout RNA-Seq assay for SPAG1 is not available on ENCORE database.





57 RBPs can affect the gene expression of SPAG1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPAG1ENSG00000104450.8421.31260196.817801.097908.035707.18030HepG2AKAP1
SPAG1ENSG00000104450.8257.77470166.807400.627803.795002.91010HepG2AKAP8L
SPAG1ENSG00000104450.888.04440162.84920-0.887203.601602.70780HepG2ASCC1
SPAG1ENSG00000104450.8334.44840143.907701.2165011.4909010.09350HepG2CALR
SPAG1ENSG00000104450.886.05990154.71830-0.846203.229802.39750HepG2CIRBP
SPAG1ENSG00000104450.8281.64300167.904300.746104.972604.15630HepG2CELF1
SPAG1ENSG00000104450.8108.94890153.54100-0.495002.041701.31590HepG2DDX19B
SPAG1ENSG00000104450.8279.95690188.534400.570302.493001.89630HepG2DDX3X
SPAG1ENSG00000104450.8443.15670209.387201.081506.474205.00650HepG2DDX59
SPAG1ENSG00000104450.8253.16280161.960200.644302.693502.08430HepG2DDX6
SPAG1ENSG00000104450.8277.59500167.523900.728503.045902.32690HepG2EIF4B
SPAG1ENSG00000104450.8392.74090251.486600.643005.204104.42650HepG2ETF1
SPAG1ENSG00000104450.8149.1832088.932500.746202.808101.65690HepG2FASTKD2
SPAG1ENSG00000104450.8423.56730168.549601.3293010.471009.10860HepG2FIP1L1
SPAG1ENSG00000104450.897.97950184.68840-0.914502.369001.43570HepG2FTO
SPAG1ENSG00000104450.8259.66490132.431000.971304.315902.54860HepG2HLTF
SPAG1ENSG00000104450.888.39400149.55320-0.758602.644501.96510HepG2HNRNPC
SPAG1ENSG00000104450.8142.20980227.99570-0.681003.601002.79180HepG2HNRNPF
SPAG1ENSG00000104450.888.23440163.07540-0.886103.515902.73350HepG2HNRNPK
SPAG1ENSG00000104450.8104.31710164.50070-0.657102.944602.25100HepG2HNRNPL
SPAG1ENSG00000104450.8128.24000199.49570-0.637502.383701.79430HepG2HNRNPLL
SPAG1ENSG00000104450.8245.60480163.690700.585302.530701.88250HepG2IGF2BP2
SPAG1ENSG00000104450.8334.21560153.622401.121302.768701.78660HepG2IGF2BP3
SPAG1ENSG00000104450.8342.35910174.634700.971106.153905.24210HepG2MATR3
SPAG1ENSG00000104450.8109.72100179.05550-0.706603.461802.60990HepG2NOL12
SPAG1ENSG00000104450.8330.46910208.390900.665102.724501.84410HepG2PABPC1
SPAG1ENSG00000104450.8243.14990159.181500.611102.717402.00170HepG2PABPC4
SPAG1ENSG00000104450.8336.12350204.464100.717003.294101.63690HepG2PNPT1
SPAG1ENSG00000104450.851.11920131.94640-1.368007.159205.98470HepG2PRPF4
SPAG1ENSG00000104450.8174.98410105.075300.735702.862202.03940HepG2PRPF8
SPAG1ENSG00000104450.8109.15080170.91410-0.646902.637902.05350HepG2PUF60
SPAG1ENSG00000104450.8104.41790169.08580-0.695403.337002.67590HepG2PUS1
SPAG1ENSG00000104450.8471.54270126.297101.9005016.1032014.54370HepG2RAVER1
SPAG1ENSG00000104450.8632.98500210.197401.5903030.3337028.98280HepG2RBM22
SPAG1ENSG00000104450.8254.22350103.093101.302009.999208.91840HepG2RPS19
SPAG1ENSG00000104450.8155.49810228.94770-0.558102.068201.37630HepG2RPS3A
SPAG1ENSG00000104450.8249.55340103.944201.263407.759906.52670HepG2RRP9
SPAG1ENSG00000104450.8167.65650103.484600.696002.702601.77540HepG2SERBP1
SPAG1ENSG00000104450.8111.11510246.01030-1.146702.946801.53970HepG2SF1
SPAG1ENSG00000104450.8221.92360154.940200.518302.063501.48000HepG2SF3A3
SPAG1ENSG00000104450.887.90420197.47590-1.167704.371303.50220HepG2SF3B1
SPAG1ENSG00000104450.8558.10460237.412201.2330019.8307018.81010HepG2SRFBP1
SPAG1ENSG00000104450.8249.58710159.307200.647603.506302.99020HepG2SRSF1
SPAG1ENSG00000104450.8227.74150129.609100.813105.398004.67090HepG2SRSF9
SPAG1ENSG00000104450.8132.83290206.13350-0.634003.208802.66580HepG2SSB
SPAG1ENSG00000104450.8220.33420118.024000.900503.531402.15910HepG2SUB1
SPAG1ENSG00000104450.8290.92300135.565201.101606.696305.71590HepG2SUPV3L1
SPAG1ENSG00000104450.8122.10740242.04620-0.987103.629202.41400HepG2TBRG4
SPAG1ENSG00000104450.8213.75120131.571600.700003.748202.78240HepG2TIA1
SPAG1ENSG00000104450.8369.96130144.165201.3596011.4500010.14610HepG2U2AF1
SPAG1ENSG00000104450.8303.67500176.708300.781103.456002.51780HepG2UBE2L3
SPAG1ENSG00000104450.8214.60790124.171200.789303.067501.73530HepG2XRCC5
SPAG1ENSG00000104450.868.94230133.44880-0.952802.996702.24210HepG2XRN2
SPAG1ENSG00000104450.8265.45340130.210501.027508.738307.65620HepG2ZC3H8
SPAG1ENSG00000104450.8318.42250151.122601.075105.569704.86370HepG2ZNF622
SPAG1ENSG00000104450.843.3609083.03370-0.937302.635601.99700K562AKAP8L
SPAG1ENSG00000104450.856.6760027.133701.062602.342501.67160K562EIF2S2
SPAG1ENSG00000104450.8103.2906040.908301.336104.835603.79240K562HSPD1
SPAG1ENSG00000104450.861.0482020.391301.581903.607602.67310K562RPS19
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPAG1 is not available on ENCORE database.





2 RBPs can affect the splicing of SPAG1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPAG1ENSG00000104450.8chr8+101251467101251632101245398101245765101252630101252743-0.292000.000380.00618excludedHepG2U2AF2
MXESPAG1ENSG00000104450.8chr8+101245638101245765101251467101251632101243383101243516101252630101252999-0.423000.001630.073122includedK562UTP18

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPAG1 is not avaliable on ENCORE database.