PTPN4

General Information

Gene Name       : PTPN4
Gene ID             : ENSG00000088179.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PTPN4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPN4ENSG00000088179.816.3113.1814.74ENCSR000AEF
HepG2PTPN4ENSG00000088179.817.5916.0216.80ENCSR985KAT
K562PTPN4ENSG00000088179.814.8811.9413.41ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPN4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPN4 RNA is bound by 17 proteins.  







eCLIP assay for PTPN4 is not avaliable on ENCORE database.





17 proteins are bound to PTPN4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2120689990120690047+3'-UTR,5'-UTR,CDS,intron-Proximal3.553613.55754HepG2U2AF2
chr2120690093120690160+3'-UTR,CDS,intron-Proximal4.657474.35676HepG2PRPF8
chr2120709548120709625+3'-UTR,CDS,intron-Proximal3.723453.93645HepG2PPIG
chr2120734580120734647+3'-UTR,CDS3.306924.74886HepG2BCLAF1
chr2120709631120709709+3'-UTR,CDS,intron-Proximal3.560024.34695HepG2BCLAF1
chr2120735330120735426+3'-UTR3.331504.03817HepG2KHSRP
chr2120703969120704003+3'-UTR,CDS,intron-Proximal3.761623.87469HepG2BCLAF1
chr2120677624120677685+3'-UTR,5'-UTR,CDS,intron-Proximal3.674113.16095HepG2U2AF2
chr2120692372120692431+3'-UTR,CDS,intron-Proximal3.083533.00343HepG2GRWD1
chr2120725410120725489+3'-UTR,CDS,intron-Proximal4.111849.80976HepG2BCLAF1
chr2120714593120714652+3'-UTR,CDS3.891895.36555HepG2BCLAF1
chr2120718380120718524+3'-UTR,CDS,intron-Proximal5.1738413.80283HepG2BCLAF1
chr2120677655120677717+3'-UTR,5'-UTR,CDS4.761624.78529HepG2BCLAF1
chr2120690001120690073+3'-UTR,5'-UTR,CDS3.580345.97823HepG2BCLAF1
chr2120723071120723145+3'-UTR,CDS,intron-Proximal5.254077.95223HepG2BCLAF1
chr2120702655120702693+3'-UTR,CDS,intron-Proximal3.776504.93978HepG2BCLAF1
chr2120673858120673910+5'-UTR,intron-Distal4.251014.00239HepG2KHSRP
chr2120567406120567468+5'-UTR,CDS,intron-Proximal3.662933.91876HepG2U2AF2
chr2120673452120673517+5'-UTR,intron-Distal4.365065.07255HepG2KHSRP
chr2120658297120658386+5'-UTR,CDS,intron-Proximal4.533787.53358HepG2BCLAF1
chr2120673160120673230+5'-UTR,intron-Distal3.261325.14345HepG2KHSRP
chr2120640078120640122+CDS,intron-Proximal3.084456.33024HepG2BCLAF1
chr2120639672120639704+CDS,intron-Proximal3.580343.28366HepG2BCLAF1
chr2120620186120620220+CDS,intron-Proximal4.416557.97334HepG2BCLAF1
chr2120635079120635119+CDS,intron-Proximal3.902274.93978HepG2BCLAF1
chr2120634895120634940+CDS,intron-Proximal3.918128.08603HepG2BCLAF1
chr2120620110120620222+CDS,intron-Proximal3.234376.24463HepG2GRWD1
chr2120567498120567569+CDS,intron-Proximal3.668136.23335HepG2GRWD1
chr2120645497120645536+intron-Distal3.903793.01456K562EXOSC5
chr2120647241120647308+intron-Distal3.144573.93186HepG2MATR3
chr2120552605120552733+intron-Distal5.4223710.04692HepG2HNRNPM
chr2120646473120646509+intron-Distal3.288733.14999K562EXOSC5
chr2120707749120707848+intron-Distal3.998783.73283HepG2HNRNPL
chr2120647230120647293+intron-Distal4.394493.59909K562EXOSC5
chr2120646634120646740+intron-Distal3.9041612.21417HepG2MATR3
chr2120705242120705309+intron-Distal3.725044.51091HepG2HNRNPL
chr2120728004120728077+intron-Distal6.4466921.47104HepG2QKI
chr2120645126120645176+intron-Distal3.653055.30446HepG2SUGP2
chr2120646206120646255+intron-Distal4.053573.01445K562EXOSC5
chr2120517981120518078+intron-Distal,intron-Proximal3.516347.29501HepG2RBFOX2
chr2120689722120689812+intron-Distal5.004284.40618K562PTBP1
chr2120648158120648260+intron-Distal5.240067.87294HepG2MATR3
chr2120646624120646741+intron-Distal3.028263.18966K562MATR3
chr2120648467120648529+intron-Distal4.653056.10726HepG2SUGP2
chr2120681066120681149+intron-Distal3.999196.88352HepG2HNRNPL
chr2120661418120661490+intron-Distal3.095934.14321HepG2HNRNPL
chr2120567661120567749+intron-Distal,intron-Proximal3.667993.24603K562KHSRP
chr2120646686120646745+intron-Distal3.987405.37814HepG2HNRNPM
chr2120685836120685897+intron-Distal3.307683.05068HepG2U2AF2
chr2120647657120647714+intron-Distal4.765746.25174HepG2MATR3
chr2120524061120524104+intron-Distal4.531013.26170K562EIF4G2
chr2120645112120645171+intron-Distal4.500984.80399K562EXOSC5
chr2120523466120523559+intron-Distal4.171073.35109HepG2TIAL1
chr2120646280120646378+intron-Distal3.959515.89423HepG2HNRNPM
chr2120732886120732990+intron-Distal4.241894.58424HepG2ILF3
chr2120689741120689816+intron-Distal4.3757815.38529HepG2PTBP1
chr2120709198120709270+intron-Distal3.911973.22073HepG2KHSRP
chr2120646144120646240+intron-Distal4.212744.72162K562KHSRP
chr2120646080120646129+intron-Distal4.338503.89085K562EXOSC5
chr2120530767120530869+intron-Distal3.302773.06005HepG2QKI
chr2120624420120624539+intron-Distal4.180014.37030K562KHSRP
chr2120728077120728135+intron-Distal4.442833.83958HepG2QKI
chr2120523449120523547+intron-Distal6.1016911.47680K562EIF4G2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPN4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPN4 is not available on ENCORE database.

  • 62 RBPs can affect the levels of PTPN4.  








The Knockdown/knockout RNA-Seq assay for PTPN4 is not available on ENCORE database.





62 RBPs can affect the gene expression of PTPN4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPN4ENSG00000088179.4649.20800536.736700.274402.061801.52210HepG2ACO1
PTPN4ENSG00000088179.4657.70540539.259600.286402.116501.43300HepG2AKAP8L
PTPN4ENSG00000088179.4676.53100536.621400.334203.014802.32710HepG2CKAP4
PTPN4ENSG00000088179.4900.58470665.928700.435401.961901.32320HepG2CNOT7
PTPN4ENSG00000088179.4662.87670467.644400.503204.024702.90950HepG2DDX24
PTPN4ENSG00000088179.4845.90990539.926500.647602.590101.64640HepG2DDX59
PTPN4ENSG00000088179.4405.76530504.91630-0.315401.976201.37080HepG2DNAJC21
PTPN4ENSG00000088179.4395.70770500.42440-0.338702.628101.98990HepG2DNAJC2
PTPN4ENSG00000088179.4652.74910440.080500.568703.447202.20120HepG2AGO1
PTPN4ENSG00000088179.41419.10280683.499101.0539011.129209.79410HepG2EIF4B
PTPN4ENSG00000088179.4904.42810668.622100.435704.442803.42330HepG2EIF4G1
PTPN4ENSG00000088179.41524.820901025.504400.5722011.2107010.13250HepG2ETF1
PTPN4ENSG00000088179.4517.88650384.604900.429202.772801.98600HepG2FUBP3
PTPN4ENSG00000088179.4518.50630708.24980-0.449902.852502.15020HepG2FXR1
PTPN4ENSG00000088179.4887.94140657.070000.434302.829802.15770HepG2G3BP1
PTPN4ENSG00000088179.4472.02890617.51730-0.387603.911303.12060HepG2HNRNPL
PTPN4ENSG00000088179.4779.92570514.394900.600404.999204.17970HepG2HNRNPLL
PTPN4ENSG00000088179.4448.98590563.24730-0.327102.439501.86780HepG2HNRNPU
PTPN4ENSG00000088179.4877.82400667.920200.394202.504401.85880HepG2IGF2BP2
PTPN4ENSG00000088179.4619.34960461.644800.423903.043401.56080HepG2NIP7
PTPN4ENSG00000088179.4616.87460456.080800.435602.655901.92230HepG2NSUN2
PTPN4ENSG00000088179.4883.03260649.546700.442902.987402.23910HepG2PABPC4
PTPN4ENSG00000088179.4746.36040616.907700.274701.976401.44970HepG2PCBP1
PTPN4ENSG00000088179.4723.86840519.669800.478005.144204.12400HepG2PRPF4
PTPN4ENSG00000088179.4550.46200370.427600.571404.397103.40310HepG2PRPF8
PTPN4ENSG00000088179.4873.22950681.027500.358502.546501.97260HepG2PUM1
PTPN4ENSG00000088179.4987.77030680.558900.537405.584404.64460HepG2PUM2
PTPN4ENSG00000088179.41186.37230679.880200.8031013.2816012.06070HepG2QKI
PTPN4ENSG00000088179.4994.96490617.006700.689308.347307.22530HepG2RBM25
PTPN4ENSG00000088179.4854.08830698.589600.289802.124001.63760HepG2NELFE
PTPN4ENSG00000088179.4502.89690366.453200.456502.368101.63430HepG2RRP9
PTPN4ENSG00000088179.4717.16450509.172100.494103.784202.97030HepG2SF3B1
PTPN4ENSG00000088179.41094.99640566.535100.950607.900706.57640HepG2SNRNP70
PTPN4ENSG00000088179.4829.45790682.160800.282002.088501.66160HepG2SRSF1
PTPN4ENSG00000088179.4881.76390633.418900.477105.297704.47240HepG2SRSF5
PTPN4ENSG00000088179.4766.85550554.952000.466505.278104.55920HepG2SRSF9
PTPN4ENSG00000088179.4794.09780522.894300.602703.281301.96690HepG2SUB1
PTPN4ENSG00000088179.4717.86690477.780900.587303.201402.47990HepG2SUPV3L1
PTPN4ENSG00000088179.41052.72010613.081500.7799012.8343011.76030HepG2TAF15
PTPN4ENSG00000088179.4439.98300552.18980-0.327702.385201.85380HepG2TRIM56
PTPN4ENSG00000088179.4811.80610626.728300.373202.524101.69310HepG2TUFM
PTPN4ENSG00000088179.4829.76910539.221700.621705.353804.49570HepG2U2AF1
PTPN4ENSG00000088179.4916.02830615.250800.574103.495702.30370HepG2XRCC6
PTPN4ENSG00000088179.4443.78230810.65050-0.8692014.5984013.40080K562AGGF1
PTPN4ENSG00000088179.4686.05190890.70780-0.376602.931201.91090K562AKAP8
PTPN4ENSG00000088179.4494.83650843.50030-0.769407.849306.69550K562AKAP8L
PTPN4ENSG00000088179.4563.54090695.32660-0.303201.849601.35130K562AQR
PTPN4ENSG00000088179.4517.27950693.49330-0.422903.695702.40820K562CPEB4
PTPN4ENSG00000088179.4187.41100296.00490-0.659403.929502.63880K562CSTF2
PTPN4ENSG00000088179.4830.635101143.17410-0.460804.242103.02540K562CELF1
PTPN4ENSG00000088179.4855.41990717.582300.253401.991201.42170K562DDX47
PTPN4ENSG00000088179.4339.51040536.53470-0.660205.289004.08990K562FIP1L1
PTPN4ENSG00000088179.4611.74740373.147800.713104.963803.95170K562G3BP2
PTPN4ENSG00000088179.4508.11460724.05290-0.510904.079303.16340K562GRSF1
PTPN4ENSG00000088179.4434.40830648.50270-0.578105.226503.72220K562HNRNPL
PTPN4ENSG00000088179.4311.41180461.72740-0.568204.797903.61330K562HNRNPU
PTPN4ENSG00000088179.4712.68730895.22890-0.329002.206201.47930K562KIF1C
PTPN4ENSG00000088179.4743.050101002.87350-0.432604.247203.08110K562MBNL1
PTPN4ENSG00000088179.4453.26900551.09070-0.281901.962401.32080K562NSUN2
PTPN4ENSG00000088179.4387.49220609.08650-0.652505.519004.29540K562PPIG
PTPN4ENSG00000088179.4202.02020304.44670-0.591703.050102.09460K562PSIP1
PTPN4ENSG00000088179.4336.40570536.48360-0.673306.514305.52860K562PTBP1
PTPN4ENSG00000088179.4479.34010836.65210-0.803608.068807.18850K562PUS1
PTPN4ENSG00000088179.4508.31720815.08260-0.681205.001404.22540K562RBM15
PTPN4ENSG00000088179.4340.34540514.56590-0.596404.639203.51820K562RBM22
PTPN4ENSG00000088179.4390.12070557.10690-0.514004.989403.77710K562SRPK2
PTPN4ENSG00000088179.4377.40740525.90360-0.478702.165101.53130K562SRSF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPN4 is not available on ENCORE database.





2 RBPs can affect the splicing of PTPN4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTPN4ENSG00000088179.4chr2+120674187120674266120672754120672818120677644120677817-0.330000.000470.09435excludedK562WDR43
SEPTPN4ENSG00000088179.4chr2+120703916120704000120702656120702816120704093120704150-0.220000.000230.00356excludedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPN4 is not avaliable on ENCORE database.