PTPMT1

General Information

Gene Name       : PTPMT1
Gene ID             : ENSG00000110536.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PTPMT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PTPMT1ENSG00000110536.1337.3638.9338.14ENCSR000AEF
HepG2PTPMT1ENSG00000110536.1372.2269.5670.89ENCSR985KAT
K562PTPMT1ENSG00000110536.1348.1149.1848.64ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PTPMT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PTPMT1 RNA is bound by 6 proteins.  







eCLIP assay for PTPMT1 is not avaliable on ENCORE database.





6 proteins are bound to PTPMT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr114759144147591491+3'-UTR,CDS,intron-Distal,intron-Proximal3.992114.98250K562AQR
chr114759327247593341+3'-UTR,intron-Proximal4.2685212.73651K562PABPC4
chr114759316147593231+3'-UTR,CDS3.433349.89088K562YBX3
chr114759323447593276+3'-UTR4.078764.51688K562YBX3
chr114759332047593388+3'-UTR,intron-Proximal4.088453.43895HepG2LARP4
chr114759305647593116+3'-UTR,CDS3.239354.30677K562YBX3
chr114759125047591428+3'-UTR,CDS,intron-Distal,intron-Proximal3.098564.48159HepG2LARP4
chr114758714647587297+5'-UTR,CDS3.841315.32471K562DDX3X
chr114758713247587228+5'-UTR,CDS6.0674335.67470HepG2DDX3X
chr114758737647587392+CDS,intron-Proximal5.169914.57565HepG2DDX3X
chr114758723347587365+CDS,intron-Proximal5.6166042.55685HepG2DDX3X
chr114758750047587537+CDS3.352673.33524K562DDX3X
chr114758752647587592+CDS,intron-Proximal5.9552811.46503HepG2PRPF8
chr114759118747591301+CDS,intron-Distal,intron-Proximal4.312117.15298K562AQR
chr114758753747587584+CDS,intron-Proximal4.6751712.86643K562AQR
chr114758745647587489+CDS,intron-Proximal3.937633.86664K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PTPMT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PTPMT1 is not available on ENCORE database.

  • 48 RBPs can affect the levels of PTPMT1.  








The Knockdown/knockout RNA-Seq assay for PTPMT1 is not available on ENCORE database.





48 RBPs can affect the gene expression of PTPMT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PTPMT1ENSG00000110536.9662.20450841.16370-0.345103.021602.30920HepG2AUH
PTPMT1ENSG00000110536.9426.03080690.03910-0.695705.915004.94350HepG2CPSF6
PTPMT1ENSG00000110536.9608.52920814.44110-0.420504.796203.86010HepG2DAZAP1
PTPMT1ENSG00000110536.9547.63190448.565700.287802.146101.40450HepG2DDX19B
PTPMT1ENSG00000110536.9600.95240453.570600.405802.539401.88660HepG2DDX21
PTPMT1ENSG00000110536.9212.98090406.56980-0.932809.762608.50840HepG2DNAJC21
PTPMT1ENSG00000110536.9665.58720803.54960-0.271802.060201.31960HepG2EIF4G1
PTPMT1ENSG00000110536.9458.65690965.74450-1.0742022.0875020.66740HepG2ETF1
PTPMT1ENSG00000110536.9653.19670473.955500.462703.577402.62790HepG2EWSR1
PTPMT1ENSG00000110536.9259.62010350.15230-0.431602.507501.39640HepG2FAM120A
PTPMT1ENSG00000110536.9374.31540558.12600-0.576303.207402.36480HepG2FUBP3
PTPMT1ENSG00000110536.9643.05170799.79350-0.314702.494001.81180HepG2HNRNPF
PTPMT1ENSG00000110536.9615.94090787.57540-0.354602.449501.76640HepG2IGF2BP1
PTPMT1ENSG00000110536.91172.76590856.182200.453802.720801.89830HepG2LARP4
PTPMT1ENSG00000110536.9883.15760629.698200.487902.920602.27530HepG2MATR3
PTPMT1ENSG00000110536.9437.21170644.57250-0.560002.049201.49990HepG2NCBP2
PTPMT1ENSG00000110536.9516.12540661.89820-0.358901.945501.31300HepG2NSUN2
PTPMT1ENSG00000110536.9549.73070770.94350-0.487903.960203.26130HepG2PUF60
PTPMT1ENSG00000110536.9678.61720818.41060-0.270202.303301.75200HepG2PUM1
PTPMT1ENSG00000110536.9603.90990817.80030-0.437403.729702.95600HepG2PUM2
PTPMT1ENSG00000110536.9487.14700685.01060-0.491802.118501.63250HepG2NELFE
PTPMT1ENSG00000110536.9471.71560637.88680-0.435401.834501.31800HepG2RECQL
PTPMT1ENSG00000110536.9525.54480381.173900.463303.102702.45630HepG2RPS19
PTPMT1ENSG00000110536.9570.68680739.25580-0.373403.565002.78590HepG2SLBP
PTPMT1ENSG00000110536.9608.38640471.029100.369103.236002.54900HepG2SMN1
PTPMT1ENSG00000110536.9681.40250911.69880-0.420004.903704.29040HepG2SRFBP1
PTPMT1ENSG00000110536.9589.10220785.74580-0.415503.936903.12830HepG2SRSF7
PTPMT1ENSG00000110536.9396.99820544.15160-0.454902.034501.54680HepG2SRSF9
PTPMT1ENSG00000110536.9541.46680444.631400.284201.848701.36970HepG2TRIM56
PTPMT1ENSG00000110536.9825.03250637.771800.371302.481701.88480HepG2U2AF1
PTPMT1ENSG00000110536.9602.46960797.28450-0.404202.160101.42580HepG2UBE2L3
PTPMT1ENSG00000110536.9691.71900569.099600.281402.066701.44800HepG2UPF1
PTPMT1ENSG00000110536.9746.33330549.448100.441704.572403.83350HepG2UTP3
PTPMT1ENSG00000110536.9486.74980625.90500-0.362803.361502.77550HepG2ZNF622
PTPMT1ENSG00000110536.9691.74360969.56650-0.487103.749003.08650K562AQR
PTPMT1ENSG00000110536.9760.56230957.30130-0.331903.283802.07180K562CPEB4
PTPMT1ENSG00000110536.9544.83220730.95430-0.424003.385902.51520K562CPSF6
PTPMT1ENSG00000110536.91217.75690990.717500.297603.223602.52880K562DDX47
PTPMT1ENSG00000110536.9330.65730481.80060-0.543103.595202.54480K562EFTUD2
PTPMT1ENSG00000110536.91038.97640739.840300.489804.319503.24460K562FIP1L1
PTPMT1ENSG00000110536.91303.936401025.306500.346702.773902.01720K562GRSF1
PTPMT1ENSG00000110536.9329.76050527.16710-0.676805.613504.79260K562HNRNPC
PTPMT1ENSG00000110536.9938.01350608.492800.624305.173803.85560K562HNRNPM
PTPMT1ENSG00000110536.91335.143001003.117400.412403.379602.50120K562HSPD1
PTPMT1ENSG00000110536.9301.95440485.73230-0.685805.229303.87040K562PCBP2
PTPMT1ENSG00000110536.91168.17940839.812600.476004.146303.11530K562PPIG
PTPMT1ENSG00000110536.9339.13530535.23130-0.658304.636503.18090K562NELFE
PTPMT1ENSG00000110536.9561.09220905.00180-0.6897010.347808.84560K562SF3A3
PTPMT1ENSG00000110536.9760.13650927.19190-0.286602.742601.81000K562SRPK2
PTPMT1ENSG00000110536.9682.21830549.160600.312902.053601.34480K562SYNCRIP
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PTPMT1 is not available on ENCORE database.





17 RBPs can affect the splicing of PTPMT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.602000.000000.00000excludedK562SRSF1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.180000.000960.02031excludedK562SF3B4
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.249000.000030.00221excludedK562PRPF8
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.131000.001380.07595excludedHepG2RBM22
SEPTPMT1ENSG00000110536.9chr11+4759125147591443475870094758753847593022475939120.217000.000930.01327includedHepG2U2AF2
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.385000.000000.00000excludedK562FXR1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.191000.000320.05127excludedHepG2HNRNPA1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.168000.000000.00197excludedK562APOBEC3C
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.194000.000950.04924excludedK562EFTUD2
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.181000.000020.00181excludedHepG2MATR3
SEPTPMT1ENSG00000110536.9chr11+4759125147591443475870094758753847593022475939120.137000.003270.05872includedK562U2AF1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.552000.000000.00000excludedHepG2SRSF1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.166000.000060.01151excludedHepG2SSB
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.166000.000170.01145excludedHepG2PCBP1
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.142000.000080.02216excludedK562EIF4G2
SEPTPMT1ENSG00000110536.9chr11+4759125147591443475870094758753847593022475939120.114000.000550.02171includedK562UTP18
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.183000.000390.06424excludedK562EIF3G
SEPTPMT1ENSG00000110536.9chr11+475912514759144347587009475875384759302247593912-0.193000.000010.00064excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PTPMT1 is not avaliable on ENCORE database.