POLR2K

General Information

Gene Name       : POLR2K
Gene ID             : ENSG00000147669.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: POLR2K)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878POLR2KENSG00000147669.10173.07140.70156.88ENCSR000AEF
HepG2POLR2KENSG00000147669.1033.3562.8248.09ENCSR985KAT
K562POLR2KENSG00000147669.1087.19106.3396.76ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for POLR2K is not avaliable on ENCORE database.



Proteins bound to RNA
  • POLR2K RNA is bound by 9 proteins.  







eCLIP assay for POLR2K is not avaliable on ENCORE database.





9 proteins are bound to POLR2K RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8101165601101165704+3'-UTR3.977678.01516HepG2LARP4
chr8101165573101165619+3'-UTR4.354217.37833K562PABPC4
chr8101166044101166095+3'-UTR4.0590316.91921K562PUM2
chr8101165870101165925+3'-UTR3.824578.53392K562FAM120A
chr8101165597101165686+3'-UTR3.427073.60227HepG2TIAL1
chr8101165580101165705+3'-UTR3.245369.69815K562FAM120A
chr8101165586101165679+3'-UTR3.615464.84840HepG2DDX55
chr8101165600101165675+3'-UTR3.519558.56865K562PUM2
chr8101165924101165977+3'-UTR5.134145.94928K562UPF1
chr8101165998101166084+3'-UTR4.562356.81876K562UPF1
chr8101165925101165970+3'-UTR3.506166.83930K562FAM120A
chr8101166110101166177+3'-UTR5.225157.24234K562FAM120A
chr8101165870101165916+3'-UTR3.3406510.83345K562PUM2
chr8101166047101166093+3'-UTR4.795129.58395K562FAM120A
chr8101165885101165907+3'-UTR3.140445.15194K562UPF1
chr8101165907101165924+3'-UTR5.206346.64872K562UPF1
chr8101162880101162914+5'-UTR4.556157.97419K562DDX3X
chr8101162880101162938+5'-UTR,intron-Proximal4.863194.77410HepG2SUB1
chr8101163572101163636+5'-UTR,CDS,intron-Proximal3.1189214.45552K562DDX3X
chr8101162914101162938+5'-UTR,intron-Proximal3.4376312.02688K562DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for POLR2K is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for POLR2K is not available on ENCORE database.

  • 83 RBPs can affect the levels of POLR2K.  








The Knockdown/knockout RNA-Seq assay for POLR2K is not available on ENCORE database.





83 RBPs can affect the gene expression of POLR2K :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
POLR2KENSG00000147669.6616.14890445.737100.467003.166302.02870HepG2AATF
POLR2KENSG00000147669.6457.37110679.37440-0.570803.670802.59070HepG2ABCF1
POLR2KENSG00000147669.6334.94520562.31760-0.747506.503605.05120HepG2ADAR
POLR2KENSG00000147669.61528.347201063.396700.523203.992103.37050HepG2AKAP1
POLR2KENSG00000147669.6644.35120504.438300.353102.152201.61930HepG2BOP1
POLR2KENSG00000147669.6852.22360615.523200.469304.244003.31280HepG2CALR
POLR2KENSG00000147669.6478.37580888.75490-0.8936015.7281014.44290HepG2CELF1
POLR2KENSG00000147669.6612.26360955.58820-0.6422011.151109.81980HepG2DAZAP1
POLR2KENSG00000147669.6396.17240554.33840-0.484603.156802.08330HepG2DDX5
POLR2KENSG00000147669.6454.01630841.23630-0.889809.460008.40230HepG2EIF2S1
POLR2KENSG00000147669.6662.04800905.11850-0.451202.323001.68990HepG2EIF4B
POLR2KENSG00000147669.6870.33940548.957000.664807.698906.31340HepG2EWSR1
POLR2KENSG00000147669.6629.33140937.90480-0.575604.770703.87780HepG2FXR1
POLR2KENSG00000147669.6611.93390870.11380-0.507803.546102.79700HepG2G3BP1
POLR2KENSG00000147669.6643.02990923.64650-0.522504.090002.99930HepG2G3BP2
POLR2KENSG00000147669.6359.90370525.02710-0.544803.073602.40340HepG2GPKOW
POLR2KENSG00000147669.6602.15520880.90670-0.548904.581903.70220HepG2HNRNPK
POLR2KENSG00000147669.6662.69200884.47650-0.416502.656301.99340HepG2IGF2BP2
POLR2KENSG00000147669.6487.53000889.58590-0.867607.343805.62240HepG2KHSRP
POLR2KENSG00000147669.6326.57840513.54550-0.653107.613505.98260HepG2KIF1C
POLR2KENSG00000147669.6680.76950938.23170-0.462803.256202.54500HepG2MAGOH
POLR2KENSG00000147669.6671.79720965.74670-0.523603.886603.14060HepG2NCBP2
POLR2KENSG00000147669.6605.06860860.14070-0.507503.676302.85110HepG2PABPC4
POLR2KENSG00000147669.6641.78570867.25980-0.434404.213303.49190HepG2PCBP1
POLR2KENSG00000147669.6398.80020563.39060-0.498504.445103.53140HepG2PPIL4
POLR2KENSG00000147669.6622.69930882.48750-0.503005.542404.82370HepG2PTBP1
POLR2KENSG00000147669.6737.45950959.51480-0.379703.234402.50870HepG2PUM2
POLR2KENSG00000147669.6912.86500632.496400.529202.426401.76330HepG2RAVER1
POLR2KENSG00000147669.61375.88270808.222500.7674014.7883013.78380HepG2RBM22
POLR2KENSG00000147669.6663.88920982.10870-0.564907.481406.66880HepG2NELFE
POLR2KENSG00000147669.6579.80970914.72820-0.657809.687208.63810HepG2RECQL
POLR2KENSG00000147669.6812.57790558.866200.539903.470002.71210HepG2SF3A3
POLR2KENSG00000147669.6748.74780918.75070-0.295202.522401.95360HepG2SF3B4
POLR2KENSG00000147669.6622.31730867.34230-0.479006.150405.17020HepG2SLBP
POLR2KENSG00000147669.6513.63430656.01190-0.353003.281602.59130HepG2SMN1
POLR2KENSG00000147669.61687.11340912.862700.8860026.9627025.81700HepG2SRFBP1
POLR2KENSG00000147669.61170.90930958.990100.287902.926402.44380HepG2SRSF1
POLR2KENSG00000147669.6536.85750780.20100-0.539306.944406.14140HepG2SRSF9
POLR2KENSG00000147669.6869.220701015.70910-0.224701.855001.32690HepG2SUCLG1
POLR2KENSG00000147669.6468.93330613.81650-0.388402.871502.36410HepG2TIAL1
POLR2KENSG00000147669.6429.54980619.25790-0.527705.666704.91230HepG2TRIM56
POLR2KENSG00000147669.6550.27620355.451400.630403.177302.36550HepG2UCHL5
POLR2KENSG00000147669.6650.84880478.511700.443704.000603.29980HepG2UTP3
POLR2KENSG00000147669.6756.84720522.257700.535106.966805.98090HepG2ZC3H8
POLR2KENSG00000147669.61035.866701560.19690-0.590906.599904.71780K562ABCF1
POLR2KENSG00000147669.61086.43190808.555900.426105.216304.47730K562AGGF1
POLR2KENSG00000147669.61069.54560841.334800.346102.564501.93490K562AKAP8L
POLR2KENSG00000147669.63392.412601517.633501.1604014.2819013.09480K562AQR
POLR2KENSG00000147669.6689.28230874.01020-0.342603.193102.16380K562BCLAF1
POLR2KENSG00000147669.6573.71970975.82400-0.766305.919104.77620K562CPSF6
POLR2KENSG00000147669.6495.57160663.06680-0.420103.163902.02310K562CSTF2
POLR2KENSG00000147669.61797.127902232.69270-0.313102.910301.91060K562CELF1
POLR2KENSG00000147669.61242.01830905.362800.456005.926904.57740K562DKC1
POLR2KENSG00000147669.6831.897501188.23490-0.514304.802503.88870K562EIF2S2
POLR2KENSG00000147669.6396.27670513.55230-0.374002.556901.46130K562EIF4B
POLR2KENSG00000147669.6715.77750898.62650-0.328202.507601.30750K562EXOSC5
POLR2KENSG00000147669.61462.350501121.565400.382703.284602.35620K562FIP1L1
POLR2KENSG00000147669.6951.24480593.033500.6816010.383309.29670K562FXR1
POLR2KENSG00000147669.61046.00280750.285300.479302.977402.24100K562G3BP2
POLR2KENSG00000147669.6744.28750931.70500-0.324002.182901.47590K562GPKOW
POLR2KENSG00000147669.6995.054801583.58490-0.670307.591406.32400K562GRSF1
POLR2KENSG00000147669.6702.79480906.82630-0.367703.066001.93410K562HNRNPA1
POLR2KENSG00000147669.6711.14240943.53790-0.407902.628302.04450K562HNRNPC
POLR2KENSG00000147669.6651.42450842.40730-0.370902.528801.44500K562HNRNPF
POLR2KENSG00000147669.61230.07880815.099300.593604.532902.91930K562HNRNPK
POLR2KENSG00000147669.61557.17490922.526700.755204.388503.19740K562HNRNPM
POLR2KENSG00000147669.62090.899601520.572100.459404.641703.61630K562HSPD1
POLR2KENSG00000147669.6621.13140840.93980-0.437103.278201.57400K562LSM11
POLR2KENSG00000147669.6473.68430850.62720-0.8446012.1156010.55950K562MTPAP
POLR2KENSG00000147669.61091.40330701.101800.638403.828102.74530K562NAA15
POLR2KENSG00000147669.6732.38370945.19250-0.368004.610403.67750K562NSUN2
POLR2KENSG00000147669.6661.51700928.73710-0.489502.959301.46900K562NUSAP1
POLR2KENSG00000147669.6995.71890763.143400.383702.865801.87080K562PCBP2
POLR2KENSG00000147669.61685.983701273.231900.405003.560002.61040K562PPIG
POLR2KENSG00000147669.61585.34460690.094001.1998022.6385020.47660K562PRPF8
POLR2KENSG00000147669.6554.43090845.93240-0.609504.697803.47590K562PSIP1
POLR2KENSG00000147669.62524.074001981.557800.349003.218502.33980K562PUF60
POLR2KENSG00000147669.61760.83860834.403301.0773019.6847018.26510K562PUS1
POLR2KENSG00000147669.61200.71300812.975500.562507.704206.74520K562RBM15
POLR2KENSG00000147669.6591.74800771.57150-0.382802.690401.71330K562RCC2
POLR2KENSG00000147669.6898.27290703.046000.353402.189101.46650K562RPS19
POLR2KENSG00000147669.6976.85780781.282400.322202.280101.30490K562SAFB
POLR2KENSG00000147669.6946.97870780.624800.278602.136101.38600K562SF3B4
POLR2KENSG00000147669.61048.56250816.925600.360002.931602.20700K562SRSF1
POLR2KENSG00000147669.6602.02520771.52600-0.357902.409801.43970K562SRSF5
POLR2KENSG00000147669.61166.67830879.420600.407702.133501.41090K562SYNCRIP
POLR2KENSG00000147669.6635.75440797.52380-0.327102.338101.59360K562TIA1
POLR2KENSG00000147669.6480.69620813.67360-0.759306.519205.03030K562TIAL1
POLR2KENSG00000147669.6680.47670864.16390-0.344802.256501.41490K562TRIM56
POLR2KENSG00000147669.61015.703601311.87620-0.369202.670301.32100K562TRIP6
POLR2KENSG00000147669.61093.42000727.787600.587204.976103.42150K562U2AF1
POLR2KENSG00000147669.61037.01780751.476900.464505.065503.98340K562U2AF2
POLR2KENSG00000147669.6508.52400707.27250-0.476003.057001.98160K562UCHL5
POLR2KENSG00000147669.6493.027701002.20210-1.0234022.6480020.83900K562UPF1
POLR2KENSG00000147669.6625.41840857.56160-0.455404.187203.10310K562WDR3
POLR2KENSG00000147669.61290.476301709.84400-0.406002.878701.99530K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for POLR2K is not available on ENCORE database.





3 RBPs can affect the splicing of POLR2K :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPOLR2KENSG00000147669.6chr8+101163494101163644101162811101162937101164051101164437-0.068000.000000.00000excludedK562AQR
A3SSPOLR2KENSG00000147669.6chr8+101164051101164144101164063101164144101163494101163644-0.072000.000000.00000shorterK562SF3B4
MXEPOLR2KENSG00000147669.6chr8+1011635741011636441011640511011641441011628111011629371011655211011662300.144000.008920.089451includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for POLR2K is not avaliable on ENCORE database.