PAAF1

General Information

Gene Name       : PAAF1
Gene ID             : ENSG00000175575.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PAAF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PAAF1ENSG00000175575.1229.2921.8325.56ENCSR000AEF
HepG2PAAF1ENSG00000175575.1227.7735.4431.60ENCSR985KAT
K562PAAF1ENSG00000175575.1227.4225.8826.65ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PAAF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PAAF1 RNA is bound by 8 proteins.  







eCLIP assay for PAAF1 is not avaliable on ENCORE database.





8 proteins are bound to PAAF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr117363859973638684+3'-UTR5.235287.79622K562PUM2
chr117358811073588133+5'-UTR,CDS,intron-Distal,intron-Proximal3.819793.52230K562AQR
chr117358803273588129+5'-UTR,CDS,intron-Distal,intron-Proximal3.440584.02244HepG2NCBP2
chr117358983773589874+5'-UTR,CDS,intron-Proximal4.893964.97342HepG2PPIG
chr117358813373588156+5'-UTR,intron-Distal,intron-Proximal4.929354.65563K562AQR
chr117358805973588117+5'-UTR,CDS,intron-Distal,intron-Proximal3.867997.09278HepG2PPIG
chr117358980873589916+5'-UTR,CDS,intron-Proximal3.696056.88667K562BUD13
chr117358985773589971+5'-UTR,CDS,intron-Distal,intron-Proximal4.453535.47926K562AQR
chr117358982273589837+5'-UTR,CDS,intron-Proximal4.386816.64430HepG2PPIG
chr117359839673598499+5'-UTR,CDS,intron-Proximal3.876013.82000HepG2GRWD1
chr117358982373589865+5'-UTR,CDS,intron-Proximal3.660223.90826K562ZNF622
chr117362056273620616+CDS3.657383.02850K562YBX3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PAAF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PAAF1 is not available on ENCORE database.

  • 83 RBPs can affect the levels of PAAF1.  








The Knockdown/knockout RNA-Seq assay for PAAF1 is not available on ENCORE database.





83 RBPs can affect the gene expression of PAAF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PAAF1ENSG00000175575.8566.26850462.165600.293002.090701.54770HepG2ACO1
PAAF1ENSG00000175575.8530.15930726.43460-0.454402.482201.97570HepG2AKAP1
PAAF1ENSG00000175575.8312.90650464.33250-0.569405.115904.10030HepG2AKAP8L
PAAF1ENSG00000175575.8565.80310866.51130-0.614908.435807.34630HepG2AUH
PAAF1ENSG00000175575.8218.35340374.96520-0.780104.444303.32850HepG2BCLAF1
PAAF1ENSG00000175575.8379.06510554.67470-0.549204.329803.39000HepG2CALR
PAAF1ENSG00000175575.8354.20020462.05970-0.383502.870402.19670HepG2CKAP4
PAAF1ENSG00000175575.8500.37390664.87140-0.410103.544002.83510HepG2CELF1
PAAF1ENSG00000175575.8488.85410695.86610-0.509403.335602.65700HepG2DDX3X
PAAF1ENSG00000175575.8258.80010424.23040-0.713003.752802.86810HepG2DDX55
PAAF1ENSG00000175575.8391.97580564.24570-0.525602.198501.33130HepG2DDX59
PAAF1ENSG00000175575.8421.25190597.77100-0.504902.881902.25280HepG2DDX6
PAAF1ENSG00000175575.8251.02450400.35100-0.673403.718202.42430HepG2AGO1
PAAF1ENSG00000175575.8251.62800574.64420-1.1914012.7157011.50540HepG2EIF2S1
PAAF1ENSG00000175575.8220.11200355.14270-0.690202.101601.30560HepG2EIF3D
PAAF1ENSG00000175575.8452.27950618.31310-0.451102.060201.46230HepG2EIF4B
PAAF1ENSG00000175575.8527.25550675.62060-0.357702.095901.38000HepG2EIF4G2
PAAF1ENSG00000175575.8715.43060994.83120-0.475605.517904.71800HepG2ETF1
PAAF1ENSG00000175575.8356.97580608.58420-0.769605.929704.84510HepG2FIP1L1
PAAF1ENSG00000175575.8201.88210316.22140-0.647403.051302.10780HepG2GEMIN5
PAAF1ENSG00000175575.8182.18320327.01140-0.844004.803102.95360HepG2HNRNPA0
PAAF1ENSG00000175575.8473.49960657.00610-0.472504.463303.32570HepG2HNRNPA2B1
PAAF1ENSG00000175575.8305.41530419.86630-0.459202.771501.82150HepG2HNRNPM
PAAF1ENSG00000175575.8174.07380465.80430-1.4200010.315608.03280HepG2HSPD1
PAAF1ENSG00000175575.8408.50050509.75810-0.319501.929501.31630HepG2IGF2BP1
PAAF1ENSG00000175575.8373.39870604.17190-0.694205.451804.53260HepG2IGF2BP2
PAAF1ENSG00000175575.8339.31920566.99760-0.740702.527401.59250HepG2IGF2BP3
PAAF1ENSG00000175575.8464.03810677.93320-0.546903.123502.23830HepG2LARP4
PAAF1ENSG00000175575.8448.47330640.96930-0.515203.396702.66920HepG2MAGOH
PAAF1ENSG00000175575.8370.83660492.49960-0.409302.393901.63800HepG2MSI2
PAAF1ENSG00000175575.8342.06510659.73640-0.947609.199408.08500HepG2NCBP2
PAAF1ENSG00000175575.8184.93480389.47050-1.074505.440603.87770HepG2NONO
PAAF1ENSG00000175575.8236.31300353.49000-0.581002.256301.46900HepG2PABPC1
PAAF1ENSG00000175575.8281.29530587.53160-1.0626010.905909.49800HepG2PABPC4
PAAF1ENSG00000175575.8384.05920611.77980-0.671708.224207.26890HepG2PCBP1
PAAF1ENSG00000175575.8708.41680540.375500.390503.546002.67970HepG2PRPF4
PAAF1ENSG00000175575.8520.13250676.69020-0.379602.507901.93680HepG2PUF60
PAAF1ENSG00000175575.8432.35760718.34200-0.7324011.7746010.73020HepG2PUM1
PAAF1ENSG00000175575.8444.98680717.81390-0.689807.653606.56170HepG2PUM2
PAAF1ENSG00000175575.8161.21090441.15900-1.452309.941408.66340HepG2RAVER1
PAAF1ENSG00000175575.8605.13550831.50310-0.458504.582403.95940HepG2RBM22
PAAF1ENSG00000175575.8358.18840611.87470-0.772508.105407.00200HepG2RBM25
PAAF1ENSG00000175575.8377.63060506.01630-0.422202.309601.41190HepG2RBM27
PAAF1ENSG00000175575.8559.33590692.78920-0.308702.264901.76520HepG2NELFE
PAAF1ENSG00000175575.8298.26430433.22660-0.538502.430501.54470HepG2RPS10
PAAF1ENSG00000175575.8258.86670388.33400-0.585102.859802.04630HepG2RPS3A
PAAF1ENSG00000175575.8174.97540323.82520-0.888104.890003.87800HepG2RRP9
PAAF1ENSG00000175575.8195.90070346.85620-0.824204.114002.97180HepG2SERBP1
PAAF1ENSG00000175575.8372.06800553.56040-0.573203.153802.43390HepG2SF3A3
PAAF1ENSG00000175575.8403.48710531.97480-0.398802.054701.44130HepG2SF3B1
PAAF1ENSG00000175575.8417.51300648.12110-0.634407.188506.30670HepG2SF3B4
PAAF1ENSG00000175575.8520.13010648.85170-0.319002.566201.88720HepG2SLBP
PAAF1ENSG00000175575.8309.53790449.44460-0.538002.760001.80520HepG2SMNDC1
PAAF1ENSG00000175575.8612.46200939.16680-0.616809.531308.75350HepG2SRFBP1
PAAF1ENSG00000175575.8521.98870668.13960-0.356102.883302.24440HepG2SRSF5
PAAF1ENSG00000175575.8345.51160508.59330-0.557805.129504.22830HepG2SRSF7
PAAF1ENSG00000175575.8229.93140337.79600-0.554902.686901.60420HepG2STIP1
PAAF1ENSG00000175575.8630.19310759.85320-0.269902.144001.58350HepG2SUCLG1
PAAF1ENSG00000175575.8250.45860422.34090-0.753804.143203.34010HepG2SUPV3L1
PAAF1ENSG00000175575.8825.15990608.030700.440404.323503.64650HepG2TAF15
PAAF1ENSG00000175575.8329.84210523.99340-0.667805.165904.22030HepG2TARDBP
PAAF1ENSG00000175575.8507.22390661.10660-0.382302.550601.71470HepG2TUFM
PAAF1ENSG00000175575.8204.46230520.57650-1.3483015.5290013.99180HepG2U2AF1
PAAF1ENSG00000175575.8232.49850666.67270-1.519804.086102.87440HepG2U2AF2
PAAF1ENSG00000175575.8152.77660249.50760-0.707703.444702.60190HepG2UCHL5
PAAF1ENSG00000175575.8340.36160504.60230-0.568105.148603.76190HepG2UTP18
PAAF1ENSG00000175575.8330.84970473.96750-0.518604.337903.61490HepG2UTP3
PAAF1ENSG00000175575.8282.12220539.92190-0.9364014.4748013.46700HepG2ZNF622
PAAF1ENSG00000175575.8288.89170440.63240-0.609003.331401.89720HepG2ZRANB2
PAAF1ENSG00000175575.81110.26710927.513300.259402.500801.95640K562AGGF1
PAAF1ENSG00000175575.8594.547401077.12710-0.8573010.427909.39830K562AQR
PAAF1ENSG00000175575.81250.719601012.677800.304503.131702.15630K562ATP5C1
PAAF1ENSG00000175575.8791.054701013.39220-0.357303.672302.93530K562DDX47
PAAF1ENSG00000175575.8342.00690536.32720-0.649105.034203.78460K562EFTUD2
PAAF1ENSG00000175575.8377.27670574.23270-0.606003.913302.65750K562EIF3D
PAAF1ENSG00000175575.8461.29850621.70670-0.430502.335101.77100K562FXR1
PAAF1ENSG00000175575.8503.68130651.10200-0.370402.303701.57900K562GPKOW
PAAF1ENSG00000175575.8377.71970630.87330-0.740007.194206.27550K562HNRNPC
PAAF1ENSG00000175575.8724.06210552.253100.390702.209201.38130K562HNRNPM
PAAF1ENSG00000175575.8636.72850868.62590-0.448104.594703.43870K562HNRNPU
PAAF1ENSG00000175575.81232.208201024.204100.266602.063501.36110K562KIF1C
PAAF1ENSG00000175575.8618.05060815.15210-0.399303.053702.16990K562MAGOH
PAAF1ENSG00000175575.8478.62110725.27290-0.599605.341003.97110K562PCBP2
PAAF1ENSG00000175575.8326.06340521.90840-0.678604.909103.91260K562PRPF8
PAAF1ENSG00000175575.81079.851601355.43750-0.327902.673801.87070K562PUF60
PAAF1ENSG00000175575.8540.20720759.37820-0.491304.029302.99620K562RBM22
PAAF1ENSG00000175575.8419.32210619.13840-0.562203.570302.45950K562SF3B1
PAAF1ENSG00000175575.8343.44810639.13460-0.8960011.9645010.10600K562SF3B4
PAAF1ENSG00000175575.8554.58540776.40680-0.485404.322803.44300K562SRSF1
PAAF1ENSG00000175575.81166.40600880.897700.404903.160201.69050K562SSRP1
PAAF1ENSG00000175575.8543.23080785.76020-0.532504.355403.46100K562TARDBP
PAAF1ENSG00000175575.8445.46140615.33990-0.466103.836402.88990K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PAAF1 is not available on ENCORE database.





4 RBPs can affect the splicing of PAAF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPAAF1ENSG00000175575.8chr11+7359797373598144735898237358986473598398735985020.238000.002930.03441includedHepG2U2AF2
SEPAAF1ENSG00000175575.8chr11+7359797373598144735898237358986473598398735985020.164000.000280.00416includedK562AQR
SEPAAF1ENSG00000175575.8chr11+7359797373598144735898237358986473598398735985020.350000.000000.00095includedHepG2HNRNPL
SEPAAF1ENSG00000175575.8chr11+736113147361146573610190736102897362044373620638-0.069000.004210.06070excludedK562HNRNPC

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PAAF1 is not avaliable on ENCORE database.