MKKS

General Information

Gene Name       : MKKS
Gene ID             : ENSG00000125863.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MKKS)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MKKSENSG00000125863.199.326.698.01ENCSR000AEF
HepG2MKKSENSG00000125863.1917.5026.7722.13ENCSR985KAT
K562MKKSENSG00000125863.199.5211.8910.71ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MKKS is not avaliable on ENCORE database.



Proteins bound to RNA
  • MKKS RNA is bound by 9 proteins.  







eCLIP assay for MKKS is not avaliable on ENCORE database.





9 proteins are bound to MKKS RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr201040114310401223-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal5.2414418.46362HepG2PRPF8
chr201040134310401408-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.4115216.60954K562DDX3X
chr201039444210394513-3'-UTR,intron-Distal4.083555.36555HepG2BCLAF1
chr201039426210394348-3'-UTR,intron-Distal3.787623.69311HepG2CSTF2
chr201041475110414844-5'-UTR,intron-Distal4.2680119.97724HepG2DDX3X
chr201041469610414806-5'-UTR,intron-Distal4.0642818.15782HepG2PRPF8
chr201041475410414825-5'-UTR,intron-Distal4.5238620.64321K562DDX3X
chr201041475910414818-5'-UTR,intron-Distal5.434193.73688K562GEMIN5
chr201041482510414851-5'-UTR,intron-Distal5.060994.97000K562DDX3X
chr201040747910407538-intron-Distal5.274487.68989HepG2QKI
chr201041464710414730-intron-Distal3.868488.97789HepG2EFTUD2
chr201040753810407581-intron-Distal3.663295.42334HepG2QKI
chr201040644210406517-intron-Distal4.324254.51735HepG2QKI
chr201040688510406982-intron-Distal5.277578.20307HepG2QKI
chr201039781210397895-intron-Distal3.167723.63132HepG2HNRNPC
chr201040651710406598-intron-Distal5.4525510.44346HepG2QKI
chr201040448410404554-intron-Distal4.688105.58765HepG2QKI
chr201040099210401093-intron-Distal,intron-Proximal3.082493.31157HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MKKS is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MKKS is not available on ENCORE database.

  • 76 RBPs can affect the levels of MKKS.  








The Knockdown/knockout RNA-Seq assay for MKKS is not available on ENCORE database.





76 RBPs can affect the gene expression of MKKS :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MKKSENSG00000125863.131495.039201007.012200.5700011.8453010.77500HepG2ACO1
MKKSENSG00000125863.131212.88490982.270700.304202.093501.56820HepG2BOP1
MKKSENSG00000125863.13900.79620715.796200.331602.297701.31010HepG2CSTF2
MKKSENSG00000125863.131083.92940931.368800.218702.091601.35810HepG2DDX19B
MKKSENSG00000125863.13800.516501030.20980-0.363902.563401.90680HepG2DDX21
MKKSENSG00000125863.131944.193601487.525200.386202.563101.96790HepG2DDX6
MKKSENSG00000125863.131243.37080963.452900.367904.441003.62000HepG2DKC1
MKKSENSG00000125863.13943.869801430.11530-0.599505.754004.91740HepG2EIF2S1
MKKSENSG00000125863.131047.89850828.884500.338202.521001.40810HepG2EIF2S2
MKKSENSG00000125863.131236.59350972.480600.346502.962801.84980HepG2EIF3G
MKKSENSG00000125863.131207.79110802.785500.589204.860902.45370HepG2EIF3H
MKKSENSG00000125863.133068.215101901.752100.6900019.7680018.40730HepG2ETF1
MKKSENSG00000125863.131382.85130984.082600.490705.542904.35780HepG2EWSR1
MKKSENSG00000125863.131277.865801594.48500-0.319402.097101.49180HepG2FXR1
MKKSENSG00000125863.13744.06510977.16740-0.393202.978202.31060HepG2HNRNPA1
MKKSENSG00000125863.132001.780401625.483900.300303.493102.46060HepG2HNRNPA2B1
MKKSENSG00000125863.131189.024101529.25440-0.363104.761003.85220HepG2HNRNPF
MKKSENSG00000125863.131340.974701611.37950-0.265003.185702.46570HepG2HNRNPL
MKKSENSG00000125863.13887.576801079.71970-0.282702.749902.14460HepG2HNRNPU
MKKSENSG00000125863.13832.295401410.94860-0.761502.965501.94820HepG2IGF2BP3
MKKSENSG00000125863.131153.964001512.32260-0.390202.184301.30600HepG2KHSRP
MKKSENSG00000125863.13539.14260749.82700-0.475904.095002.61990HepG2NAA15
MKKSENSG00000125863.131189.191001641.80360-0.465303.666502.94160HepG2NCBP2
MKKSENSG00000125863.131341.307101753.97520-0.387003.057102.25620HepG2NOL12
MKKSENSG00000125863.13671.898201045.97990-0.638502.586301.53210HepG2NONO
MKKSENSG00000125863.13863.450601462.24100-0.760008.679907.41980HepG2PABPC4
MKKSENSG00000125863.13587.21050878.95960-0.581904.368003.37650HepG2PRPF8
MKKSENSG00000125863.131463.434701775.94600-0.279202.846802.16740HepG2PUM2
MKKSENSG00000125863.131599.920401055.591000.599803.287402.52170HepG2RAVER1
MKKSENSG00000125863.132051.428301589.512400.367904.797104.16210HepG2RBM22
MKKSENSG00000125863.131201.814101409.67450-0.230102.201501.64410HepG2RECQL
MKKSENSG00000125863.131225.94620961.546000.350404.610103.81330HepG2SAFB2
MKKSENSG00000125863.131595.632001190.236100.422802.704102.03820HepG2SF3A3
MKKSENSG00000125863.131337.619201605.13850-0.263003.757902.96030HepG2SLBP
MKKSENSG00000125863.131897.181301477.953900.360205.378204.77380HepG2SRSF1
MKKSENSG00000125863.132041.146901558.739400.388906.757706.02360HepG2SSB
MKKSENSG00000125863.13857.718701328.42720-0.6311010.680609.69360HepG2TAF15
MKKSENSG00000125863.131039.45660834.625500.316503.567702.82040HepG2ZC3H8
MKKSENSG00000125863.131542.514401160.910100.409907.614906.82430HepG2ZNF622
MKKSENSG00000125863.13546.90290723.11500-0.402903.748203.10550K562AGGF1
MKKSENSG00000125863.131853.580301412.518000.391903.619002.17770K562APOBEC3C
MKKSENSG00000125863.13575.352901448.43000-1.3320021.6947020.22910K562AQR
MKKSENSG00000125863.13452.39580636.20620-0.491903.229002.28480K562BOP1
MKKSENSG00000125863.13713.466401238.85850-0.796105.313703.78260K562CNOT7
MKKSENSG00000125863.13494.35920676.48810-0.452503.450302.57170K562CPSF6
MKKSENSG00000125863.13444.47730576.91700-0.376302.708801.66120K562CSTF2
MKKSENSG00000125863.13368.30340520.10480-0.497903.754202.51630K562DDX3X
MKKSENSG00000125863.131664.379401235.713900.429506.921605.95530K562DDX47
MKKSENSG00000125863.13466.24700617.19190-0.404602.256101.43240K562EFTUD2
MKKSENSG00000125863.13436.00150571.23370-0.389703.239601.91660K562EIF2S1
MKKSENSG00000125863.13348.58740489.30500-0.489204.071302.62220K562EIF4B
MKKSENSG00000125863.13325.04390474.28460-0.545104.368502.68810K562EWSR1
MKKSENSG00000125863.13466.82070651.01410-0.479803.900702.35740K562EXOSC5
MKKSENSG00000125863.13435.39420583.35970-0.422102.407101.55910K562FTO
MKKSENSG00000125863.13366.86730512.60160-0.482604.005901.83080K562FUBP3
MKKSENSG00000125863.13821.86360565.067900.540406.170105.31970K562FXR1
MKKSENSG00000125863.13623.16020871.42800-0.483805.289803.74230K562GLRX3
MKKSENSG00000125863.13444.38480645.89440-0.539504.212403.23800K562GPKOW
MKKSENSG00000125863.13377.62140674.25980-0.836409.297908.25470K562HNRNPC
MKKSENSG00000125863.13986.92160731.128500.432702.861401.91310K562HNRNPM
MKKSENSG00000125863.13607.39400878.63420-0.532606.203104.85410K562HNRNPU
MKKSENSG00000125863.13570.86600766.31440-0.424802.354701.43010K562IGF2BP2
MKKSENSG00000125863.13541.05280779.46360-0.526704.744203.09810K562IGF2BP3
MKKSENSG00000125863.13362.71290551.47470-0.604503.334102.29940K562KRR1
MKKSENSG00000125863.13751.57540916.18660-0.285702.574801.79350K562MTPAP
MKKSENSG00000125863.13624.322001018.00050-0.7054014.5792013.05540K562NSUN2
MKKSENSG00000125863.13818.936301190.17950-0.539402.970501.68560K562PABPC1
MKKSENSG00000125863.13539.07140828.08760-0.619305.088103.95960K562PCBP3
MKKSENSG00000125863.13463.41330604.54900-0.383602.089501.31420K562PSIP1
MKKSENSG00000125863.132143.090701746.589700.295102.358401.60540K562PUF60
MKKSENSG00000125863.13598.80580746.28170-0.317602.047601.56710K562PUS1
MKKSENSG00000125863.13576.88270750.35210-0.379302.619301.80320K562RBM22
MKKSENSG00000125863.13378.22030551.59410-0.544404.230503.00100K562RCC2
MKKSENSG00000125863.13504.07480355.315000.504402.660101.67960K562RPS3
MKKSENSG00000125863.13750.072501004.45490-0.421304.765103.71910K562SF3A3
MKKSENSG00000125863.13345.29360522.89420-0.598704.225802.88010K562SRFBP1
MKKSENSG00000125863.13834.802901029.08100-0.301803.237502.23280K562SRPK2
MKKSENSG00000125863.13491.82190724.46490-0.558804.775403.32840K562SRSF5
MKKSENSG00000125863.13621.75620787.52240-0.341002.769501.60410K562SRSF7
MKKSENSG00000125863.13506.74520661.82890-0.385203.114101.73740K562SSB
MKKSENSG00000125863.13401.32450581.68030-0.535503.145202.06040K562SUPV3L1
MKKSENSG00000125863.13573.80720748.89930-0.384202.895702.05610K562TIA1
MKKSENSG00000125863.13369.95780581.47240-0.652304.813803.55060K562TIAL1
MKKSENSG00000125863.13379.50250617.76320-0.702905.840804.35080K562TRIM56
MKKSENSG00000125863.13838.935101079.40480-0.363604.376603.49320K562UPF1
MKKSENSG00000125863.13596.42570923.61710-0.631007.389905.91830K562WDR3
MKKSENSG00000125863.131259.999801631.86570-0.373103.483702.49670K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MKKS is not available on ENCORE database.





8 RBPs can affect the splicing of MKKS :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.101000.000030.00095excludedK562SRSF1
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.148000.000190.00521excludedK562SF3B4
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.244000.000250.00622excludedHepG2U2AF1
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.082000.000300.01007excludedHepG2HNRNPK
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.306000.000070.00154excludedHepG2U2AF2
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.124000.001190.02581excludedK562U2AF1
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.072000.001860.04171excludedHepG2SRSF1
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.170000.000340.01296excludedHepG2SF3A3
SEMKKSENSG00000125863.13chr20-103931771039457910389275103894511040117510401406-0.240000.000000.00008excludedK562U2AF2
MXEMKKSENSG00000125863.13chr20-10393177103932221039444310394579103892751038945110401175104014060.132000.000020.000791includedHepG2SRSF1
MXEMKKSENSG00000125863.13chr20-10393177103932221039444310394579103892751038945110401175104014060.170000.000150.047521includedHepG2FASTKD2
MXEMKKSENSG00000125863.13chr20-1039317710394579104011751040140610389275103894511041475510414870-0.146000.000390.067142includedHepG2DKC1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MKKS is not avaliable on ENCORE database.