MIEN1

General Information

Gene Name       : MIEN1
Gene ID             : ENSG00000141741.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: MIEN1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MIEN1ENSG00000141741.1146.9747.0847.02ENCSR000AEF
HepG2MIEN1ENSG00000141741.1140.1750.7145.44ENCSR985KAT
K562MIEN1ENSG00000141741.1182.3595.2488.79ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MIEN1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • MIEN1 RNA is bound by 8 proteins.  







eCLIP assay for MIEN1 is not avaliable on ENCORE database.





8 proteins are bound to MIEN1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr173788559437885614-3'-UTR,intron-Distal4.469454.12941K562DDX55
chr173788557137885629-3'-UTR,intron-Distal3.243833.68829K562YBX3
chr173788559437885686-3'-UTR,intron-Distal3.712297.82548HepG2LARP4
chr173788568637885748-3'-UTR,intron-Distal4.282975.47244HepG2LARP4
chr173788564537885725-3'-UTR,intron-Distal5.661505.18845K562PCBP1
chr173788663637886694-CDS,intron-Distal,intron-Proximal3.267183.05161HepG2PPIG
chr173788644437886496-CDS,intron-Distal,intron-Proximal3.371067.51172HepG2PPIG
chr173788648537886545-CDS,intron-Distal,intron-Proximal5.027418.74631K562PABPC4
chr173788667137886733-CDS,intron-Distal4.204924.17587HepG2DDX3X
chr173788665337886747-CDS,intron-Distal,intron-Proximal4.2652915.16545K562DDX3X
chr173788594337885992-CDS,intron-Distal3.999723.16051HepG2PPIG
chr173788646937886545-CDS,intron-Distal,intron-Proximal3.252483.93266K562FTO
chr173788647737886544-CDS,intron-Distal4.957797.86232HepG2LARP4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MIEN1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MIEN1 is not available on ENCORE database.

  • 71 RBPs can affect the levels of MIEN1.  








The Knockdown/knockout RNA-Seq assay for MIEN1 is not available on ENCORE database.





71 RBPs can affect the gene expression of MIEN1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MIEN1ENSG00000141741.7279.28200399.57630-0.516704.079103.36780HepG2ACO1
MIEN1ENSG00000141741.7232.03430337.02950-0.538502.624301.65140HepG2ADAR
MIEN1ENSG00000141741.71303.78340528.625601.3023018.2965017.05480HepG2AKAP1
MIEN1ENSG00000141741.7603.96630423.730000.511203.076701.98180HepG2AKAP8
MIEN1ENSG00000141741.7542.21830232.806301.2196014.6707013.44490HepG2BOP1
MIEN1ENSG00000141741.7599.61930415.543200.528903.457202.59880HepG2CIRBP
MIEN1ENSG00000141741.7192.93030297.95370-0.627003.569102.52340HepG2DDX24
MIEN1ENSG00000141741.7700.87770435.047900.687905.085804.27150HepG2DDX6
MIEN1ENSG00000141741.7437.23510339.375600.365402.283901.63990HepG2DNAJC21
MIEN1ENSG00000141741.7505.25190336.371300.586806.382405.45110HepG2DNAJC2
MIEN1ENSG00000141741.7691.60150418.137500.725906.167905.30190HepG2EIF2S1
MIEN1ENSG00000141741.7314.58190220.254800.514202.138301.33460HepG2EIF3D
MIEN1ENSG00000141741.7555.46600390.440700.508503.883902.89320HepG2EWSR1
MIEN1ENSG00000141741.7314.26840417.68050-0.410402.150001.45010HepG2FUBP3
MIEN1ENSG00000141741.7669.62660432.508600.630504.679603.82500HepG2G3BP1
MIEN1ENSG00000141741.7336.54990459.24850-0.448502.387401.56250HepG2G3BP2
MIEN1ENSG00000141741.7306.78290438.10630-0.514102.916102.19830HepG2HNRNPK
MIEN1ENSG00000141741.7714.42860460.155200.634608.763907.62960HepG2HNRNPL
MIEN1ENSG00000141741.7500.88750386.714600.373103.213502.42790HepG2ILF2
MIEN1ENSG00000141741.7357.11350230.485600.631602.392601.41080HepG2METAP2
MIEN1ENSG00000141741.7644.85130480.099900.425502.347401.76200HepG2NCBP2
MIEN1ENSG00000141741.7643.53820500.884400.361402.489301.76840HepG2NOL12
MIEN1ENSG00000141741.7121.33510205.00660-0.756703.097202.30700HepG2NSUN2
MIEN1ENSG00000141741.7290.46320394.27570-0.440803.012402.21020HepG2PRPF4
MIEN1ENSG00000141741.7700.33630507.526400.464505.255104.49120HepG2PUM1
MIEN1ENSG00000141741.7503.58640406.991600.307102.094001.53990HepG2PUS1
MIEN1ENSG00000141741.7625.00070501.871400.316402.107901.55100HepG2QKI
MIEN1ENSG00000141741.7447.29360305.444100.550202.100501.47980HepG2RAVER1
MIEN1ENSG00000141741.7402.39700270.435900.573202.376201.39540HepG2RCC2
MIEN1ENSG00000141741.7715.27500564.859100.340502.055301.45610HepG2RPLP0
MIEN1ENSG00000141741.7320.17710214.361100.578703.100702.45470HepG2RPS19
MIEN1ENSG00000141741.7426.09260337.150000.337702.141801.56230HepG2SAFB2
MIEN1ENSG00000141741.7356.59930215.076000.729404.406303.23060HepG2SERBP1
MIEN1ENSG00000141741.7492.52060393.176300.324901.918401.36670HepG2SMN1
MIEN1ENSG00000141741.7574.32740311.764300.881306.791905.23580HepG2SMNDC1
MIEN1ENSG00000141741.7268.36300409.73480-0.610505.208204.49300HepG2SRSF9
MIEN1ENSG00000141741.7436.37400281.971900.629902.293301.43170HepG2SUPT6H
MIEN1ENSG00000141741.7332.83190452.72950-0.443902.803902.24030HepG2TAF15
MIEN1ENSG00000141741.7594.64760367.877400.692706.667505.95250HepG2TIAL1
MIEN1ENSG00000141741.7468.57030371.155900.336102.318501.79310HepG2TRIM56
MIEN1ENSG00000141741.7195.69000357.38520-0.868902.018401.47280HepG2U2AF1
MIEN1ENSG00000141741.7394.14150184.757401.093009.843008.41240HepG2UCHL5
MIEN1ENSG00000141741.7378.96730259.671500.545304.179203.34870HepG2UPF1
MIEN1ENSG00000141741.7370.84530250.702700.564704.224603.50960HepG2UTP3
MIEN1ENSG00000141741.7500.26110285.589000.8086010.633909.73560HepG2ZNF622
MIEN1ENSG00000141741.71046.42710580.828600.8492016.9879015.70420K562AGGF1
MIEN1ENSG00000141741.7854.02370638.257300.420003.433802.31190K562AKAP8
MIEN1ENSG00000141741.71209.28990604.382001.000509.399208.11270K562AKAP8L
MIEN1ENSG00000141741.7866.52760634.149000.450303.247402.25290K562ATP5C1
MIEN1ENSG00000141741.7963.812301216.09530-0.335403.116402.08180K562CELF1
MIEN1ENSG00000141741.7571.91910442.491000.370102.454001.47550K562DDX3X
MIEN1ENSG00000141741.7444.55860600.94990-0.434903.832303.08320K562DDX47
MIEN1ENSG00000141741.7785.28550650.336000.271902.129101.37230K562DKC1
MIEN1ENSG00000141741.7297.83580440.53900-0.564803.622102.07300K562DNAJC21
MIEN1ENSG00000141741.7220.65190416.70970-0.917304.700703.35400K562EIF3A
MIEN1ENSG00000141741.7748.43740437.274600.775204.985203.82500K562FIP1L1
MIEN1ENSG00000141741.7332.51500457.28410-0.459702.445101.39720K562FKBP4
MIEN1ENSG00000141741.7194.20240314.84600-0.697103.335902.54550K562G3BP2
MIEN1ENSG00000141741.71234.05870873.708500.498105.076804.05150K562GRSF1
MIEN1ENSG00000141741.7536.87340359.728100.577602.410201.54500K562HNRNPM
MIEN1ENSG00000141741.7554.66450402.390600.462902.417401.47730K562IGF2BP2
MIEN1ENSG00000141741.7288.18590413.61260-0.521302.965501.42760K562KHDRBS1
MIEN1ENSG00000141741.7943.61240641.387900.556902.281801.54170K562KIF1C
MIEN1ENSG00000141741.7867.85810613.976200.499204.130502.73770K562MAK16
MIEN1ENSG00000141741.7988.94310718.518200.460804.411103.21180K562MBNL1
MIEN1ENSG00000141741.7831.02760503.630300.722405.409404.03330K562NAA15
MIEN1ENSG00000141741.7895.04350463.494800.949305.187803.71480K562PABPN1
MIEN1ENSG00000141741.7498.14170679.40080-0.447702.684501.86610K562PCBP3
MIEN1ENSG00000141741.7889.53560496.484800.841206.765705.38430K562PPIG
MIEN1ENSG00000141741.7945.093701147.75450-0.280302.431501.43590K562PUM1
MIEN1ENSG00000141741.71473.71120599.355701.297907.668606.81120K562PUS1
MIEN1ENSG00000141741.71226.04330584.002901.0699011.3131010.13360K562RBM15
MIEN1ENSG00000141741.7706.12800423.952400.735902.632901.47390K562SF1
MIEN1ENSG00000141741.7587.85510402.857200.545104.412303.52420K562SRSF1
MIEN1ENSG00000141741.7632.83430407.738900.634105.340904.34050K562TARDBP
MIEN1ENSG00000141741.7528.84330666.17980-0.333102.691301.98190K562UPF1
MIEN1ENSG00000141741.7379.94990592.79470-0.641707.893306.53310K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MIEN1 is not available on ENCORE database.





1 RBPs can affect the splicing of MIEN1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSMIEN1ENSG00000141741.7chr17-3788593737886044378859373788601437886446378865700.092000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MIEN1 is not avaliable on ENCORE database.