LSM2

General Information

Gene Name       : LSM2
Gene ID             : ENSG00000204392.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: LSM2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LSM2ENSG00000204392.1073.2688.9081.08ENCSR000AEF
HepG2LSM2ENSG00000204392.1060.3263.8662.09ENCSR985KAT
K562LSM2ENSG00000204392.10160.80172.46166.63ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LSM2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LSM2 RNA is bound by 14 proteins.  







eCLIP assay for LSM2 is not avaliable on ENCORE database.





14 proteins are bound to LSM2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr63176533731765405-3'-UTR,intron-Distal3.807267.48701K562DDX6
chr63176547031765514-3'-UTR,intron-Distal5.062227.26512HepG2LARP4
chr63176525931765329-3'-UTR,intron-Distal4.8795955.55988K562PABPC4
chr63176520731765247-3'-UTR,intron-Distal5.615218.21523HepG2SUB1
chr63176533931765416-3'-UTR,intron-Distal5.7857024.53147HepG2SUB1
chr63176528431765425-3'-UTR,intron-Distal4.5932611.53552HepG2DDX55
chr63176519131765228-3'-UTR,intron-Distal5.7395014.78848K562PABPC4
chr63176533231765414-3'-UTR,intron-Distal4.8537123.17266HepG2LARP4
chr63176533931765426-3'-UTR,intron-Distal3.443086.73551K562NOLC1
chr63176527831765318-3'-UTR,intron-Distal5.204395.77022K562DDX6
chr63176533531765404-3'-UTR,intron-Distal3.6560523.91091K562PABPC4
chr63177461731774703-5'-UTR,intron-Distal,intron-Proximal4.369257.30450K562DROSHA
chr63177461731774679-5'-UTR,intron-Distal,intron-Proximal3.215249.13522K562DDX3X
chr63177453931774582-5'-UTR,intron-Distal4.542986.35799K562PCBP1
chr63177453231774604-5'-UTR,CDS,intron-Distal,intron-Proximal3.0851812.94765K562DDX3X
chr63177453331774580-5'-UTR,CDS,intron-Distal,intron-Proximal3.166474.20287HepG2DDX3X
chr63177461631774658-5'-UTR,intron-Distal,intron-Proximal4.153703.53770HepG2DDX3X
chr63177461931774671-5'-UTR,intron-Distal,intron-Proximal4.592757.53622K562PCBP1
chr63176614431766259-CDS,intron-Distal,intron-Proximal5.2168910.60410K562AQR
chr63177385131773856-CDS,intron-Distal,intron-Proximal3.086427.75835K562DDX3X
chr63176565331765658-CDS,intron-Distal4.0636118.83109K562YBX3
chr63176576731765776-CDS,intron-Distal3.206147.41174K562YBX3
chr63176625931766318-CDS,intron-Distal,intron-Proximal4.591628.52787K562AQR
chr63176562631765650-CDS,intron-Distal4.2984726.54947K562YBX3
chr63177383831773854-CDS,intron-Distal,intron-Proximal3.639737.16774K562AQR
chr63177386231773900-CDS,intron-Distal,intron-Proximal3.090115.37266K562TIA1
chr63177385631773906-CDS,intron-Distal,intron-Proximal3.5454122.56628K562DDX3X
chr63176561731765626-CDS,intron-Distal4.4174926.08017K562YBX3
chr63177124431771292-intron-Distal3.325385.26194K562ILF3
chr63176613531766221-intron-Distal,intron-Proximal5.497356.71458K562EFTUD2
chr63177169531771762-intron-Distal3.897863.48745HepG2ILF3
chr63177377131773838-intron-Distal,intron-Proximal3.8559611.47097K562AQR
chr63177123731771266-intron-Distal3.112634.93483HepG2ILF3
chr63177170331771758-intron-Distal3.190313.37821K562ILF3
chr63177444431774528-intron-Distal,intron-Proximal3.907157.16374K562AQR
chr63177121431771244-intron-Distal4.527095.25643K562ILF3
chr63177121931771237-intron-Distal3.038634.56790HepG2ILF3
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LSM2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LSM2 is not available on ENCORE database.

  • 80 RBPs can affect the levels of LSM2.  








The Knockdown/knockout RNA-Seq assay for LSM2 is not available on ENCORE database.





80 RBPs can affect the gene expression of LSM2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LSM2ENSG00000204392.6562.29110455.033400.305202.101701.42070HepG2AKAP8L
LSM2ENSG00000204392.6265.44610410.57280-0.629204.141703.06150HepG2BCLAF1
LSM2ENSG00000204392.6590.49810760.37070-0.364803.120102.44530HepG2CELF1
LSM2ENSG00000204392.6357.36450464.68640-0.378902.034701.36110HepG2DDX55
LSM2ENSG00000204392.6504.07470700.87410-0.475502.963202.34940HepG2EIF2S1
LSM2ENSG00000204392.6532.16940754.17360-0.503002.641801.96890HepG2EIF4B
LSM2ENSG00000204392.6724.71440936.11520-0.369303.646102.97090HepG2ETF1
LSM2ENSG00000204392.6245.40570386.73900-0.656204.327502.76700HepG2FKBP4
LSM2ENSG00000204392.6180.27610356.73800-0.984703.529202.37700HepG2FTO
LSM2ENSG00000204392.6482.34840724.95620-0.587804.301103.48090HepG2G3BP1
LSM2ENSG00000204392.6538.59840769.72760-0.515103.707802.66720HepG2G3BP2
LSM2ENSG00000204392.6211.21010448.35600-1.086006.582204.36320HepG2HLTF
LSM2ENSG00000204392.6513.51980744.71870-0.536306.775805.76460HepG2HNRNPL
LSM2ENSG00000204392.6270.56260385.25180-0.509802.580801.96900HepG2HNRNPLL
LSM2ENSG00000204392.6536.78500736.87660-0.457102.929602.23840HepG2IGF2BP2
LSM2ENSG00000204392.6620.27730862.90100-0.476302.789301.95570HepG2LARP4
LSM2ENSG00000204392.6579.03970781.85110-0.433202.697802.04960HepG2MAGOH
LSM2ENSG00000204392.6633.24600804.70640-0.345701.864401.33780HepG2NCBP2
LSM2ENSG00000204392.6127.99370426.88190-1.7378011.283708.99970HepG2NONO
LSM2ENSG00000204392.6234.38200341.60160-0.543502.759502.01240HepG2NSUN2
LSM2ENSG00000204392.6433.11870716.56070-0.726306.283305.20700HepG2PABPC4
LSM2ENSG00000204392.6544.33740748.64830-0.459805.045104.26290HepG2PCBP1
LSM2ENSG00000204392.6463.27100761.74380-0.7174010.141809.22280HepG2PTBP1
LSM2ENSG00000204392.6572.16370773.87930-0.435702.264201.71660HepG2PUF60
LSM2ENSG00000204392.6673.68810820.91090-0.285101.883401.32420HepG2PUM2
LSM2ENSG00000204392.6433.94230825.05950-0.9270014.4577013.18740HepG2QKI
LSM2ENSG00000204392.6342.05370748.76720-1.1303017.4457015.85230HepG2RBM25
LSM2ENSG00000204392.6624.65610847.77580-0.440604.694004.02390HepG2NELFE
LSM2ENSG00000204392.6542.07130789.53690-0.542506.551405.66050HepG2RECQL
LSM2ENSG00000204392.6347.89750731.85260-1.072907.819506.49220HepG2RPS3A
LSM2ENSG00000204392.6258.00750354.39180-0.457902.251001.53470HepG2RRP9
LSM2ENSG00000204392.6679.85880500.766900.441001.950701.38190HepG2SF3A3
LSM2ENSG00000204392.6563.69760793.13430-0.492605.582204.79290HepG2SF3B4
LSM2ENSG00000204392.6573.70260742.05090-0.371203.602302.81860HepG2SLBP
LSM2ENSG00000204392.6752.55590883.73210-0.231801.790101.36060HepG2SRFBP1
LSM2ENSG00000204392.6568.46070764.10550-0.426704.194003.45210HepG2SRSF5
LSM2ENSG00000204392.6381.41590673.46710-0.8202013.0694012.02750HepG2SRSF9
LSM2ENSG00000204392.6530.13340767.30850-0.533506.462705.73930HepG2SSB
LSM2ENSG00000204392.6727.12040868.98790-0.257102.120701.56230HepG2SUCLG1
LSM2ENSG00000204392.6261.10980462.53290-0.824906.280505.32220HepG2SUPV3L1
LSM2ENSG00000204392.6196.87160309.98590-0.654903.756702.61410HepG2TFIP11
LSM2ENSG00000204392.6375.64550518.29280-0.464404.136703.47520HepG2TRIM56
LSM2ENSG00000204392.6551.29600756.06420-0.455703.641702.62470HepG2TUFM
LSM2ENSG00000204392.6340.57810800.29320-1.2325013.4644011.57160HepG2UBE2L3
LSM2ENSG00000204392.6681.91280428.764100.669308.711607.74400HepG2UTP3
LSM2ENSG00000204392.6328.42480465.81080-0.504204.378103.56390HepG2ZC3H8
LSM2ENSG00000204392.63046.804701900.931300.6805020.7173019.27840K562AGGF1
LSM2ENSG00000204392.62668.420902088.832000.353203.477102.34470K562AKAP8
LSM2ENSG00000204392.62829.677401978.004200.516504.757003.89330K562AKAP8L
LSM2ENSG00000204392.62637.895602075.400600.345904.712503.48460K562ATP5C1
LSM2ENSG00000204392.62470.317702153.844700.197702.034301.46090K562DDX47
LSM2ENSG00000204392.62965.868302128.480600.478504.588403.41870K562DKC1
LSM2ENSG00000204392.61788.031102090.24820-0.225302.226601.57080K562EIF2S2
LSM2ENSG00000204392.62559.316501935.808700.402703.991802.96060K562FIP1L1
LSM2ENSG00000204392.6908.178101323.72540-0.543604.882003.63220K562FTO
LSM2ENSG00000204392.61849.230501421.820500.379105.311504.51050K562FXR1
LSM2ENSG00000204392.6796.125901144.63110-0.523803.471802.66180K562G3BP2
LSM2ENSG00000204392.61056.697701383.45520-0.388702.832501.39370K562GEMIN5
LSM2ENSG00000204392.63454.997902785.556900.310603.142902.33910K562GRSF1
LSM2ENSG00000204392.61189.095201579.82760-0.409904.196403.47680K562HNRNPC
LSM2ENSG00000204392.62345.590801592.187000.558802.813501.87530K562HNRNPM
LSM2ENSG00000204392.6804.092001090.23470-0.439203.362401.71800K562KHDRBS1
LSM2ENSG00000204392.62565.463302099.160400.289302.703501.88910K562KIF1C
LSM2ENSG00000204392.62655.484702009.410100.402103.755902.43730K562MAK16
LSM2ENSG00000204392.63012.872302351.589400.357402.268101.45760K562MBNL1
LSM2ENSG00000204392.62189.141101648.293500.409302.613401.76010K562NAA15
LSM2ENSG00000204392.61035.523801359.88940-0.393102.921101.57980K562NONO
LSM2ENSG00000204392.62100.643701226.861800.775802.756101.76790K562PABPN1
LSM2ENSG00000204392.61314.005301909.27400-0.539105.197604.05510K562PCBP3
LSM2ENSG00000204392.61046.694201464.48370-0.484606.088804.90550K562POLR2G
LSM2ENSG00000204392.62685.822602197.463300.289402.195001.46790K562PPIG
LSM2ENSG00000204392.61823.223801342.807100.441103.998803.09680K562PRPF8
LSM2ENSG00000204392.63113.308301961.644900.666309.719808.75040K562PUS1
LSM2ENSG00000204392.62832.249201911.321200.5673011.2671010.09110K562RBM15
LSM2ENSG00000204392.61229.219301545.72510-0.330502.337101.35080K562NELFE
LSM2ENSG00000204392.61612.911701913.24020-0.246402.428001.66020K562SF3A3
LSM2ENSG00000204392.62096.615101288.668200.702102.831401.58810K562SNRNP200
LSM2ENSG00000204392.61832.105501501.853300.286702.496801.81890K562SRSF1
LSM2ENSG00000204392.61322.021901666.94280-0.334503.481601.76230K562SRSF9
LSM2ENSG00000204392.61796.469102539.96760-0.499605.664803.67600K562SSRP1
LSM2ENSG00000204392.61682.581302323.16980-0.465404.290402.66670K562STAU1
LSM2ENSG00000204392.6892.444101300.00270-0.542704.582403.24910K562SUPV3L1
LSM2ENSG00000204392.6911.050001192.70720-0.388603.087201.39410K562TBRG4
LSM2ENSG00000204392.61725.413502264.73980-0.392403.502801.90640K562TRIP6
LSM2ENSG00000204392.6956.484101375.95530-0.524604.967503.55910K562UCHL5
LSM2ENSG00000204392.61714.107302055.97200-0.262403.607402.79530K562UPF1
LSM2ENSG00000204392.61463.811901759.23630-0.265202.168901.39540K562WDR3
LSM2ENSG00000204392.61555.797601829.35990-0.233702.953302.07920K562WDR43
LSM2ENSG00000204392.62188.242802674.92310-0.289702.537501.71780K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LSM2 is not available on ENCORE database.





6 RBPs can affect the splicing of LSM2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SELSM2ENSG00000204392.6chr6-3177426231774394317738513177391931774531317745940.159000.000060.03899includedK562TAF15
SELSM2ENSG00000204392.6chr6-317662533176628431765766317658263177385131773919-0.058000.000000.00009excludedK562SF3B4
SELSM2ENSG00000204392.6chr6-317662533176628431765766317658263177385131773919-0.053000.000000.00000excludedK562AQR
SELSM2ENSG00000204392.6chr6-3177426231774394317738513177391931774531317745940.087000.001990.03946includedK562U2AF1
SELSM2ENSG00000204392.6chr6-317662533176628431765766317658263177385131773919-0.065000.000380.02128excludedHepG2SF3B4
SELSM2ENSG00000204392.6chr6-317662533176628431765766317658263177385131773919-0.144000.000360.09130excludedHepG2DROSHA
MXELSM2ENSG00000204392.6chr6-3176576631765826317662533176628431765172317656593177385131773919-0.088000.009760.086132includedK562DROSHA
MXELSM2ENSG00000204392.6chr6-3176576631765826317662533176628431765172317656593177385131773919-0.067000.001370.037632includedK562PPIL4
MXELSM2ENSG00000204392.6chr6-3176576631765826317662533176628431765172317656593177385131773919-0.074000.002980.043962includedK562SF3B4

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for LSM2 is not avaliable on ENCORE database.