KPNA6

General Information

Gene Name       : KPNA6
Gene ID             : ENSG00000025800.13
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: KPNA6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878KPNA6ENSG00000025800.1316.1216.7116.41ENCSR000AEF
HepG2KPNA6ENSG00000025800.1313.0921.5817.34ENCSR985KAT
K562KPNA6ENSG00000025800.1319.2420.1619.70ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for KPNA6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • KPNA6 RNA is bound by 35 proteins.  







eCLIP assay for KPNA6 is not avaliable on ENCORE database.





35 proteins are bound to KPNA6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr13263757332637672+3'-UTR,intron-Distal3.248465.41412K562PUM2
chr13263630732636355+3'-UTR,CDS,intron-Proximal3.765484.50825K562DDX24
chr13263708932637129+3'-UTR,intron-Distal5.454789.04193K562TIA1
chr13263878532638861+3'-UTR,intron-Distal3.7446414.35539K562PABPC4
chr13264154732641603+3'-UTR,intron-Distal3.511965.82813K562PABPC4
chr13262884332628906+3'-UTR,CDS4.008153.68241HepG2G3BP1
chr13262764532627691+3'-UTR,CDS,intron-Proximal5.354479.96618HepG2AQR
chr13263554832635622+3'-UTR,CDS3.876013.56019HepG2GRWD1
chr13263286332632896+3'-UTR,CDS4.047453.70678K562BUD13
chr13263842732638498+3'-UTR,intron-Distal3.751786.31152K562IGF2BP2
chr13263712932637183+3'-UTR,intron-Distal3.156514.92970K562TIA1
chr13263168932631755+3'-UTR,CDS,intron-Proximal3.572675.62662K562BUD13
chr13263685032636929+3'-UTR,intron-Distal,intron-Proximal4.093783.55542HepG2TIAL1
chr13263723132637278+3'-UTR,intron-Distal3.749263.07786HepG2UPF1
chr13263650932636544+3'-UTR3.995523.63681K562RBM15
chr13263676532636789+3'-UTR3.762606.04229K562RBM15
chr13262805032628127+3'-UTR,CDS,intron-Proximal3.350505.60389HepG2PPIG
chr13262890932628956+3'-UTR,CDS,intron-Proximal3.803926.32052K562AQR
chr13262804932628124+3'-UTR,CDS3.419383.72202HepG2G3BP1
chr13264196332642017+3'-UTR,intron-Proximal3.147007.57497K562TIA1
chr13262016432620223+3'-UTR,CDS,intron-Proximal3.285364.77916HepG2AQR
chr13262890032628983+3'-UTR,CDS,intron-Proximal3.564385.66421K562PRPF8
chr13262884832628927+3'-UTR,CDS,intron-Proximal3.970443.20743HepG2PPIG
chr13262879432628895+3'-UTR,CDS,intron-Proximal4.7576111.92069K562BUD13
chr13263688632636941+3'-UTR,intron-Distal,intron-Proximal3.7257916.31712K562TIA1
chr13262808732628179+3'-UTR,CDS,intron-Proximal3.645306.95612HepG2PRPF8
chr13264165932641687+3'-UTR,intron-Distal3.510183.95400K562UPF1
chr13262793232628013+3'-UTR,CDS,intron-Proximal5.1186032.65529K562AQR
chr13263767432637728+3'-UTR,intron-Distal4.019443.09815K562IGF2BP1
chr13263685632636886+3'-UTR,intron-Proximal3.598138.82673K562TIA1
chr13263627932636339+3'-UTR,CDS,intron-Proximal4.976927.52401K562BUD13
chr13263688232636941+3'-UTR,intron-Distal,intron-Proximal3.072534.14949K562U2AF1
chr13263811132638184+3'-UTR,intron-Distal3.1562718.41847K562UPF1
chr13262878032628869+3'-UTR,CDS,intron-Proximal3.373767.92595K562SF3B4
chr13263281332632857+3'-UTR,CDS3.482364.06757K562UCHL5
chr13262764632627697+3'-UTR,CDS,intron-Proximal5.6566734.55728K562AQR
chr13263965032639677+3'-UTR,intron-Distal3.635786.36816K562YBX3
chr13262018732620232+3'-UTR,CDS,intron-Proximal3.196707.73893K562DDX3X
chr13263561632635664+3'-UTR,CDS,intron-Proximal4.365745.23082K562DDX24
chr13263780532637844+3'-UTR,intron-Distal4.485728.51603K562UPF1
chr13262793832628048+3'-UTR,CDS,intron-Proximal3.193728.19632K562PRPF8
chr13262756532627642+3'-UTR,CDS3.154285.87296K562DDX24
chr13263811932638182+3'-UTR,intron-Distal3.458598.13602K562TIA1
chr13263685132636935+3'-UTR,intron-Distal,intron-Proximal3.164305.18546HepG2UPF1
chr13263960332639647+3'-UTR,intron-Distal3.6791710.87798K562YBX3
chr13262800632628131+3'-UTR,CDS,intron-Proximal3.166073.62863K562SRSF1
chr13264165432641698+3'-UTR,intron-Distal5.062027.26658HepG2LIN28B
chr13263684432636876+3'-UTR,intron-Proximal3.221657.08420K562HNRNPC
chr13262798632628042+3'-UTR,CDS4.162803.32446HepG2PRPF8
chr13263566032635677+3'-UTR,CDS,intron-Proximal3.388894.88100K562AQR
chr13264057432640630+3'-UTR,intron-Distal3.913693.74511K562IGF2BP1
chr13264164132641701+3'-UTR,intron-Distal6.0200717.96434K562LIN28B
chr13263639332636449+3'-UTR,CDS3.342506.26015K562RBM15
chr13263632632636421+3'-UTR,CDS3.135433.47314HepG2G3BP1
chr13262018532620222+3'-UTR,CDS,intron-Proximal3.213114.61701K562ZNF622
chr13262796632628027+3'-UTR,CDS3.938423.38114HepG2GRWD1
chr13262794032627998+3'-UTR,CDS,intron-Proximal4.152286.24305HepG2AQR
chr13263280932632902+3'-UTR,CDS,intron-Proximal3.574596.06436HepG2BCLAF1
chr13263687632636900+3'-UTR,intron-Proximal3.442138.00268K562HNRNPC
chr13263554832635650+3'-UTR,CDS3.772283.16390K562SRSF1
chr13262889532628960+3'-UTR,CDS,intron-Proximal4.253197.93461K562BUD13
chr13263844532638491+3'-UTR,intron-Distal3.429144.00685K562TIA1
chr13257388332573932+5'-UTR,intron-Distal3.341473.83677K562HNRNPM
chr13257392932574000+5'-UTR,intron-Distal3.358863.39857HepG2HNRNPM
chr13257367332573737+5'-UTR,CDS,intron-Proximal3.9990611.03053K562DDX3X
chr13257395032573998+5'-UTR,intron-Distal3.553084.63302K562HNRNPM
chr13257393232573950+5'-UTR,intron-Distal4.227654.53244K562HNRNPM
chr13257366032573737+5'-UTR,CDS,intron-Proximal4.487145.58865HepG2NCBP2
chr13262290032622962+CDS,intron-Proximal4.861683.91589K562SF3B4
chr13262500032625028+CDS,intron-Distal,intron-Proximal6.005575.06516K562PUM2
chr13262395432623962+CDS5.559034.37209K562PUM2
chr13262245432622481+CDS3.193364.89070K562UCHL5
chr13262245532622555+CDS,intron-Proximal3.595568.84415HepG2BCLAF1
chr13262390932623963+CDS,intron-Proximal3.712024.50825K562DDX24
chr13262251432622573+CDS,intron-Proximal3.625564.65365HepG2GRWD1
chr13262022232620319+CDS4.2394914.92651K562ZNF622
chr13262022832620317+CDS3.826268.81620HepG2BCLAF1
chr13262025732620326+CDS,intron-Proximal4.186853.42472HepG2FXR2
chr13262508232625134+CDS,intron-Distal,intron-Proximal4.636026.36164K562DDX24
chr13262246832622571+CDS,intron-Proximal3.100896.00907HepG2PPIG
chr13262252432622598+CDS,intron-Proximal4.212334.75655HepG2PRPF8
chr13262245232622534+CDS,intron-Proximal4.3787313.89500K562DDX24
chr13262023532620318+CDS4.631965.35719HepG2GRWD1
chr13260562532605718+intron-Distal3.023433.51696K562KHSRP
chr13262699532627064+intron-Distal3.865803.57018HepG2HNRNPK
chr13262519132625316+intron-Distal,intron-Proximal3.728254.76898K562CSTF2T
chr13262782532627927+intron-Distal,intron-Proximal3.181157.42856K562KHSRP
chr13262701132627062+intron-Distal3.962633.33442K562HNRNPK
chr13257714832577243+intron-Distal4.709846.23638HepG2QKI
chr13262517332625241+intron-Distal,intron-Proximal4.091953.12843K562PRPF8
chr13257733832577441+intron-Distal3.443823.62826K562HNRNPL
chr13257843732578492+intron-Distal4.282714.58544K562ILF3
chr13257456232574664+intron-Distal3.082056.06633K562KHSRP
chr13257373532573746+intron-Proximal4.860594.65563K562AQR
chr13262304632623097+intron-Proximal5.395796.75320K562AQR
chr13257376432573832+intron-Proximal5.190863.92230K562EFTUD2
chr13257374632573821+intron-Proximal4.062239.10472K562AQR
chr13263567732635706+intron-Proximal5.138506.75320K562AQR
chr13262770732627743+intron-Proximal3.676914.35635K562PRPF8
chr13263183432631884+intron-Proximal4.885414.13847K562AQR
chr13262769732627743+intron-Proximal6.9649322.44866K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for KPNA6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for KPNA6 is not available on ENCORE database.

  • 56 RBPs can affect the levels of KPNA6.  








The Knockdown/knockout RNA-Seq assay for KPNA6 is not available on ENCORE database.





56 RBPs can affect the gene expression of KPNA6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
KPNA6ENSG00000025800.91319.331701675.98190-0.345202.620501.64830HepG2ADAR
KPNA6ENSG00000025800.93041.066202622.297600.213602.459501.80540HepG2AUH
KPNA6ENSG00000025800.91085.790001666.42250-0.618007.083106.02250HepG2CPSF6
KPNA6ENSG00000025800.91444.040301718.69260-0.251202.479401.51950HepG2YBX3
KPNA6ENSG00000025800.9883.796001409.13270-0.673005.572503.81430HepG2DDX27
KPNA6ENSG00000025800.91355.657901829.88910-0.432803.995902.78900HepG2DDX5
KPNA6ENSG00000025800.91167.652401627.72420-0.479205.164203.85160HepG2DHX30
KPNA6ENSG00000025800.91373.741801687.64150-0.296903.273502.51300HepG2DNAJC21
KPNA6ENSG00000025800.91408.396501672.71860-0.248103.335602.63180HepG2DNAJC2
KPNA6ENSG00000025800.91875.027002370.37540-0.338205.134404.05100HepG2EIF4G1
KPNA6ENSG00000025800.91771.706602270.65310-0.358003.038802.18640HepG2EIF4G2
KPNA6ENSG00000025800.91324.199501703.80940-0.363603.318302.61880HepG2HNRNPA1
KPNA6ENSG00000025800.91551.656602188.53810-0.4962012.3774011.04660HepG2HNRNPL
KPNA6ENSG00000025800.91304.331401882.63690-0.5294011.1887010.03780HepG2HNRNPU
KPNA6ENSG00000025800.91206.275802338.28850-0.9549012.009809.57590HepG2HSPD1
KPNA6ENSG00000025800.91669.992101923.05240-0.203602.483901.78560HepG2ILF2
KPNA6ENSG00000025800.9939.456001406.70140-0.582406.292404.14990HepG2NIP7
KPNA6ENSG00000025800.91414.805801863.49670-0.397406.280905.08480HepG2PARN
KPNA6ENSG00000025800.91437.426001679.16290-0.224302.039301.39840HepG2PPIL4
KPNA6ENSG00000025800.92250.343001943.115200.211702.047501.37450HepG2PRPF4
KPNA6ENSG00000025800.91797.277202274.23480-0.339603.192202.55870HepG2PUF60
KPNA6ENSG00000025800.91020.101301755.81840-0.783405.097404.15520HepG2RAVER1
KPNA6ENSG00000025800.91764.891902516.47380-0.511809.714308.87790HepG2RBM22
KPNA6ENSG00000025800.91464.742401900.73870-0.375902.110301.41130HepG2RPS3A
KPNA6ENSG00000025800.91789.661102180.69990-0.285104.453403.59550HepG2SLBP
KPNA6ENSG00000025800.91290.224701955.17700-0.5997017.3298015.93130HepG2SMN1
KPNA6ENSG00000025800.92641.098601985.429300.411602.238001.53840HepG2SNRNP70
KPNA6ENSG00000025800.93664.120702842.238000.366307.844907.12060HepG2SRFBP1
KPNA6ENSG00000025800.91960.955602245.51250-0.195501.978301.43760HepG2SRSF5
KPNA6ENSG00000025800.92310.871101805.107000.356306.469105.68880HepG2SRSF9
KPNA6ENSG00000025800.92032.435802467.68920-0.280004.189303.58550HepG2SSB
KPNA6ENSG00000025800.91396.343001845.68480-0.402506.570305.76710HepG2TRIM56
KPNA6ENSG00000025800.91038.404301475.81140-0.507104.349003.44570HepG2XRN2
KPNA6ENSG00000025800.92184.549201917.621700.187902.257701.64280HepG2ZC3H8
KPNA6ENSG00000025800.91779.813602211.87460-0.313505.067504.38260HepG2ZNF622
KPNA6ENSG00000025800.94684.602503895.736300.265904.540603.84570K562AGGF1
KPNA6ENSG00000025800.93289.625504062.56760-0.304503.264301.91600K562APOBEC3C
KPNA6ENSG00000025800.94253.897903570.896200.252401.808501.31400K562AQR
KPNA6ENSG00000025800.91505.859401987.81540-0.400606.516504.49590K562DDX27
KPNA6ENSG00000025800.93337.333804003.06160-0.262404.072803.30290K562DDX47
KPNA6ENSG00000025800.95035.714204362.077200.207102.489401.66440K562DKC1
KPNA6ENSG00000025800.92153.064902677.23090-0.314304.324803.45440K562EIF2S2
KPNA6ENSG00000025800.93916.282604604.14520-0.233403.147102.14820K562EIF4G2
KPNA6ENSG00000025800.92241.288601720.008400.381805.021803.15060K562FUS
KPNA6ENSG00000025800.92339.806802727.81750-0.221402.002401.47160K562FXR1
KPNA6ENSG00000025800.92569.060803567.59380-0.473706.525805.35860K562GRSF1
KPNA6ENSG00000025800.92014.113004178.56650-1.0529024.1623022.02250K562HSPD1
KPNA6ENSG00000025800.92582.228903498.76420-0.438204.683203.57640K562PPIG
KPNA6ENSG00000025800.94261.626005235.27310-0.296904.639803.38700K562PUM2
KPNA6ENSG00000025800.94996.852604020.167900.313703.100302.53120K562PUS1
KPNA6ENSG00000025800.94981.818903917.029300.346805.427704.62210K562RBM15
KPNA6ENSG00000025800.92970.365902437.716200.285002.637701.34190K562RBM25
KPNA6ENSG00000025800.91735.289402151.50440-0.310201.996401.30830K562RPS19
KPNA6ENSG00000025800.92437.751503044.33140-0.320602.532601.57970K562RPS3
KPNA6ENSG00000025800.93946.120103342.019900.239602.953702.11340K562SF3A3
KPNA6ENSG00000025800.92578.914102045.086800.334502.413301.46810K562SUPV3L1
KPNA6ENSG00000025800.92460.240702905.99030-0.240202.192201.47110K562TIA1
KPNA6ENSG00000025800.92460.220302026.154400.279902.394001.52360K562TRIM56
KPNA6ENSG00000025800.93278.180902573.001100.349304.357303.35480K562U2AF2
KPNA6ENSG00000025800.91926.686303591.21630-0.8984039.0425036.72110K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for KPNA6 is not available on ENCORE database.





11 RBPs can affect the splicing of KPNA6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEKPNA6ENSG00000025800.9chr1+326287583262891432627961326281253263170532631831-0.086000.011740.09219excludedK562AQR
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.061000.001100.06032includedHepG2NCBP2
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.144000.000000.00003includedHepG2SFPQ
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.069000.000190.06933includedK562KHSRP
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.072000.000190.01178includedHepG2MATR3
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.175000.000000.00022includedHepG2IGF2BP3
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.052000.002200.06827includedK562TARDBP
SEKPNA6ENSG00000025800.9chr1+3260535532605465325736383257373532620188326203220.058000.000500.02347includedK562PTBP1
A3SSKPNA6ENSG00000025800.9chr1+3262881832628914326288353262891432627961326281250.068000.005650.03220longerK562AQR
A3SSKPNA6ENSG00000025800.9chr1+3262381532623962326238673262396232622922326230460.068000.000170.00138longerK562AQR
A5SSKPNA6ENSG00000025800.9chr1+3262618032626398326261803262630432627547326276470.087000.000000.00008longerK562AQR
A5SSKPNA6ENSG00000025800.9chr1+326224533262254632622453326225283262294632623046-0.175000.000590.05227shorterK562AGGF1
A5SSKPNA6ENSG00000025800.9chr1+3262245332622639326224533262254632622946326230460.113000.000340.03649longerK562UTP18
A5SSKPNA6ENSG00000025800.9chr1+3262883532629039326288353262891432631705326318310.139000.001270.09400longerK562AKAP8L
A5SSKPNA6ENSG00000025800.9chr1+3262245332622639326224533262254632622946326230460.155000.000020.00333longerK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for KPNA6 is not avaliable on ENCORE database.