GABPA

General Information

Gene Name       : GABPA
Gene ID             : ENSG00000154727.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: GABPA)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GABPAENSG00000154727.1018.1315.9217.02ENCSR000AEF
HepG2GABPAENSG00000154727.104.5910.157.37ENCSR985KAT
K562GABPAENSG00000154727.1014.9115.3615.13ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GABPA is not avaliable on ENCORE database.



Proteins bound to RNA
  • GABPA RNA is bound by 7 proteins.  







eCLIP assay for GABPA is not avaliable on ENCORE database.





7 proteins are bound to GABPA RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr212710786327107947+5'-UTR,intron-Distal,intron-Proximal3.836603.44758HepG2CSTF2T
chr212711387927113972+5'-UTR,CDS,intron-Distal,intron-Proximal3.202103.02345K562ZNF622
chr212713045427130507+CDS5.177487.93248K562RBM15
chr212712424627124315+CDS,intron-Proximal4.993204.69961K562SF3B4
chr212711302627113097+intron-Distal3.278533.48890K562KHSRP
chr212712149827121660+intron-Distal,intron-Proximal4.508394.21433K562PRPF8
chr212712144827121555+intron-Distal,intron-Proximal3.167873.55116K562KHSRP
chr212712458327124715+intron-Distal,intron-Proximal3.950793.25538K562KHSRP
chr212710814427108241+intron-Distal3.923713.19036K562XRN2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GABPA is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GABPA is not available on ENCORE database.

  • 75 RBPs can affect the levels of GABPA.  








The Knockdown/knockout RNA-Seq assay for GABPA is not available on ENCORE database.





75 RBPs can affect the gene expression of GABPA :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GABPAENSG00000154727.6706.79180872.29180-0.303502.596501.92830HepG2AUH
GABPAENSG00000154727.6342.59580586.99560-0.776805.377304.06010HepG2BCCIP
GABPAENSG00000154727.6477.15310729.43200-0.612305.365004.56590HepG2BOP1
GABPAENSG00000154727.6711.67430589.418900.271802.231401.62450HepG2CKAP4
GABPAENSG00000154727.6446.02140545.22020-0.289702.186501.43850HepG2DDX19B
GABPAENSG00000154727.6349.30240480.02970-0.458602.868602.17940HepG2DDX21
GABPAENSG00000154727.6617.43360469.663600.394602.652501.75950HepG2DDX24
GABPAENSG00000154727.6597.84940938.63580-0.650802.816202.18550HepG2DDX3X
GABPAENSG00000154727.6393.74600577.13040-0.551602.976702.17990HepG2DDX55
GABPAENSG00000154727.6530.86590806.04020-0.602502.521201.93030HepG2DDX6
GABPAENSG00000154727.6390.35870535.76600-0.456802.880202.16590HepG2DNAJC21
GABPAENSG00000154727.6300.74490530.93320-0.820006.815205.85630HepG2DNAJC2
GABPAENSG00000154727.6487.07830775.13140-0.670302.895902.28990HepG2EIF2S1
GABPAENSG00000154727.6573.85420856.73970-0.578202.296801.71180HepG2EIF4A3
GABPAENSG00000154727.61267.710401001.480200.340003.983303.28430HepG2ETF1
GABPAENSG00000154727.6580.87370759.15380-0.386202.095801.53410HepG2GPKOW
GABPAENSG00000154727.6436.14390597.63980-0.454503.047702.41410HepG2HNRNPU
GABPAENSG00000154727.6542.28540814.99860-0.587702.348001.72030HepG2IGF2BP2
GABPAENSG00000154727.6353.46270610.47510-0.788406.380805.31210HepG2ILF2
GABPAENSG00000154727.6460.33920640.87170-0.477302.652101.49010HepG2KHDRBS1
GABPAENSG00000154727.6542.157101036.03970-0.934309.321307.78840HepG2LARP4
GABPAENSG00000154727.6508.90540869.22660-0.772303.783803.05570HepG2MATR3
GABPAENSG00000154727.6503.68450889.75310-0.820904.049403.28850HepG2NCBP2
GABPAENSG00000154727.6372.73270792.61920-1.088505.308204.31870HepG2PABPC4
GABPAENSG00000154727.6600.94670766.04210-0.350202.936702.37630HepG2PTBP1
GABPAENSG00000154727.6605.88950829.69980-0.453504.359803.60140HepG2QKI
GABPAENSG00000154727.61288.57780604.133201.092708.821907.60870HepG2RAVER1
GABPAENSG00000154727.6991.86860837.057900.244701.902301.45160HepG2RBM22
GABPAENSG00000154727.6722.00080852.55370-0.239801.792201.33670HepG2NELFE
GABPAENSG00000154727.6297.94820424.80790-0.511703.239502.58090HepG2RPS19
GABPAENSG00000154727.6651.41440797.59690-0.292102.344301.79420HepG2SF3B4
GABPAENSG00000154727.61218.27060771.553000.658904.694403.35800HepG2SRSF3
GABPAENSG00000154727.6639.10990771.77020-0.272102.012901.46830HepG2SRSF5
GABPAENSG00000154727.6606.56680820.88020-0.436504.864604.22170HepG2SSB
GABPAENSG00000154727.6719.43960877.76600-0.287002.709402.09260HepG2SUCLG1
GABPAENSG00000154727.6616.83750748.22780-0.278602.069601.57170HepG2TAF15
GABPAENSG00000154727.6537.06830706.05320-0.394702.474701.78310HepG2TARDBP
GABPAENSG00000154727.6342.97990580.84560-0.760006.003805.32040HepG2TIAL1
GABPAENSG00000154727.6357.69910585.90180-0.711905.432604.69360HepG2TRIM56
GABPAENSG00000154727.6833.90850569.278500.550704.326503.55020HepG2U2AF1
GABPAENSG00000154727.6203.38890339.40600-0.738804.626103.64020HepG2UCHL5
GABPAENSG00000154727.6301.87450565.56880-0.905807.615306.42440HepG2XRN2
GABPAENSG00000154727.6384.85050757.91970-0.9777020.4907019.34180HepG2ZNF622
GABPAENSG00000154727.64369.141602184.742700.9998022.6649021.16840K562AQR
GABPAENSG00000154727.6984.060401247.05780-0.341702.314301.52310K562BOP1
GABPAENSG00000154727.61735.848802091.63090-0.269002.910801.77230K562CPEB4
GABPAENSG00000154727.61051.558101326.02330-0.334602.932202.12550K562CPSF6
GABPAENSG00000154727.6654.71230855.80240-0.386403.295102.12650K562CSTF2
GABPAENSG00000154727.61550.330701834.45820-0.242802.261601.48070K562DKC1
GABPAENSG00000154727.61057.321101279.39090-0.275002.712201.52040K562EIF2S1
GABPAENSG00000154727.61165.550601488.25330-0.352603.768502.95110K562EIF2S2
GABPAENSG00000154727.6897.311501171.79910-0.385004.054903.10150K562EIF3G
GABPAENSG00000154727.6852.445901095.87250-0.362403.560502.22360K562EIF4B
GABPAENSG00000154727.61094.816801512.41580-0.466204.604303.49080K562FIP1L1
GABPAENSG00000154727.62046.308201331.129000.620301.982901.39700K562G3BP2
GABPAENSG00000154727.61028.115401266.06040-0.300302.191801.48360K562GPKOW
GABPAENSG00000154727.6771.586501145.62140-0.570206.393305.52270K562HNRNPC
GABPAENSG00000154727.61604.148901955.87510-0.286002.421801.44140K562HNRNPL
GABPAENSG00000154727.6876.800301243.95570-0.504603.975702.84590K562HNRNPM
GABPAENSG00000154727.61589.857902050.55390-0.367103.272202.40910K562HSPD1
GABPAENSG00000154727.61194.318301633.36410-0.451705.164103.85540K562MATR3
GABPAENSG00000154727.61843.819201420.640100.376102.274001.49350K562NAA15
GABPAENSG00000154727.61383.805001600.14080-0.209602.556101.83510K562NSUN2
GABPAENSG00000154727.6904.924301191.56100-0.397002.784801.95060K562PCBP3
GABPAENSG00000154727.6840.611301118.50510-0.412103.476201.85280K562PHF6
GABPAENSG00000154727.6680.71140913.98770-0.425103.952702.98970K562POLR2G
GABPAENSG00000154727.61215.746201716.85080-0.497905.251904.06360K562PPIG
GABPAENSG00000154727.61427.60940879.895800.698108.339607.03720K562PRPF8
GABPAENSG00000154727.6729.577901027.17790-0.493604.209403.05950K562PSIP1
GABPAENSG00000154727.63882.877102805.438000.468806.211304.99200K562PUF60
GABPAENSG00000154727.63003.329901690.650200.828904.099303.45760K562PUS1
GABPAENSG00000154727.62072.619001647.358700.331204.079403.37650K562RBM15
GABPAENSG00000154727.6664.11050937.20660-0.496904.900003.57990K562RCC2
GABPAENSG00000154727.61251.628701604.66710-0.358502.759401.66910K562NELFE
GABPAENSG00000154727.61553.586001203.942800.367702.348001.45790K562SF3B1
GABPAENSG00000154727.6625.51830888.44260-0.506204.250102.89930K562SRFBP1
GABPAENSG00000154727.61100.796801558.71170-0.501806.081605.04080K562SRSF1
GABPAENSG00000154727.6763.574601066.25330-0.481702.756501.70770K562SRSF4
GABPAENSG00000154727.61150.591301521.77480-0.403404.240703.19500K562TIA1
GABPAENSG00000154727.6619.46600987.96850-0.673406.336704.86330K562TIAL1
GABPAENSG00000154727.6712.600401049.63320-0.558705.494604.05270K562TRIM56
GABPAENSG00000154727.62036.027601290.710000.657506.963705.06940K562U2AF1
GABPAENSG00000154727.62161.757701332.887200.6976013.5033011.71320K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GABPA is not available on ENCORE database.





11 RBPs can affect the splicing of GABPA :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGABPAENSG00000154727.6chr21+271121902711234327107694271078892711388327113986-0.311000.000000.00009excludedK562SRSF1
SEGABPAENSG00000154727.6chr21+271121902711234327107694271078892711388327113986-0.221000.000670.01000excludedHepG2U2AF2
SEGABPAENSG00000154727.6chr21+271138832711398627106880271073812711752027117665-0.052000.000920.01144excludedK562AQR
SEGABPAENSG00000154727.6chr21+271213462712143127117498271176652712429927124545-0.073000.000100.00234excludedK562PUS1
SEGABPAENSG00000154727.6chr21+2711219027112343271076942710788927113883271139860.150000.001270.04096includedK562UTP18
SEGABPAENSG00000154727.6chr21+271121902711234327107699271078892711388327113986-0.285000.000090.00612excludedK562PTBP1
A3SSGABPAENSG00000154727.6chr21+2713029427130515271303202713051527124299271245450.055000.000200.00167longerK562AQR
A3SSGABPAENSG00000154727.6chr21+2711385127113986271138832711398627106880271073810.059000.012120.06230longerK562AQR
A3SSGABPAENSG00000154727.6chr21+2711749827117665271175202711766527113883271139860.052000.000310.00242longerK562AQR
A3SSGABPAENSG00000154727.6chr21+2713645727136661271365202713666127134622271346760.079000.001310.00886longerK562AQR
A5SSGABPAENSG00000154727.6chr21+271213462712143127121346271214152712429927124659-0.055000.002530.08236shorterK562PUS1
A5SSGABPAENSG00000154727.6chr21+271213462712143127121346271214152712429927124545-0.063000.000790.06484shorterK562RBM15
MXEGABPAENSG00000154727.6chr21+2711752027117665271213462712141527113907271139862712429927124659-0.076000.000410.010162includedK562PUS1
MXEGABPAENSG00000154727.6chr21+27113883271139862711752027117665271068802710738127121346271214310.172000.001420.064451includedK562SF3B1
MXEGABPAENSG00000154727.6chr21+27124299271245452713032027130515271068802710738127134622271346760.095000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113851271139862712134627121431271068802710738127124299271245450.223000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113851271139862711752827117665271068802710738127121346271214310.382000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113851271139862711752027117665271068802710738127121346271214310.363000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27117520271176652712134627121431271068802710738127124299271245450.121000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113883271139862711752827117665271068802710738127121346271214310.331000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113883271139862711752027117665271068802710738127121346271214310.316000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113883271139862712134627121431271068802710738127124299271245450.288000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113765271139862712134627121431271068802710738127124299271245450.133000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113765271139862711752827117665271068802710738127121346271214310.310000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113765271139862711752027117665271068802710738127121346271214310.294000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27117528271176652712134627121431271068802710738127124299271245450.066000.000140.001601includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113871271139862712134627121431271068802710738127124299271245450.178000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113871271139862711752827117665271068802710738127121346271214310.351000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27113871271139862711752027117665271068802710738127121346271214310.335000.000000.000001includedK562AQR
MXEGABPAENSG00000154727.6chr21+27117498271176652712134627121431271138832711398627124299271245450.081000.000010.000121includedK562AQR
MXEGABPAENSG00000154727.6chr21+27117417271176652712134627121431271138832711398627124299271245450.051000.001660.014181includedK562AQR
MXEGABPAENSG00000154727.6chr21+27117477271176652712134627121431271138832711398627124299271245450.051000.001660.014181includedK562AQR
MXEGABPAENSG00000154727.6chr21+2711752027117665271213462712141527113765271139862712429927124545-0.264000.000000.000002includedK562AQR
MXEGABPAENSG00000154727.6chr21+2711752027117665271213462712141527113907271139862712429927124545-0.063000.002330.089732includedK562UTP18
MXEGABPAENSG00000154727.6chr21+27113883271139862711752027117665271068802710738127121346271214310.158000.000140.081071includedK562ABCF1
MXEGABPAENSG00000154727.6chr21+27113883271139862711752027117665271068802710738127121346271214310.196000.000610.045741includedK562RBM22
MXEGABPAENSG00000154727.6chr21+27113883271139862711752027117665271068802710738127121346271214310.297000.000120.006521includedHepG2SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GABPA is not avaliable on ENCORE database.