EXOC3

General Information

Gene Name       : EXOC3
Gene ID             : ENSG00000180104.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOC3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOC3ENSG00000180104.1511.6816.9114.29ENCSR000AEF
HepG2EXOC3ENSG00000180104.1516.6310.1513.39ENCSR985KAT
K562EXOC3ENSG00000180104.1518.6615.3917.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXOC3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXOC3 RNA is bound by 19 proteins.  







eCLIP assay for EXOC3 is not avaliable on ENCORE database.





19 proteins are bound to EXOC3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5446261446382+3'-UTR,5'-UTR,CDS,intron-Proximal3.7393513.02949K562ZNF622
chr5464476464539+3'-UTR,CDS,intron-Proximal3.902243.56019HepG2GRWD1
chr5446286446374+3'-UTR,5'-UTR,CDS3.318786.02234K562UCHL5
chr5465229465280+3'-UTR,CDS3.313523.12941K562UCHL5
chr5446264446397+3'-UTR,5'-UTR,CDS,intron-Proximal3.132704.38893K562ZNF800
chr5468592468722+3'-UTR4.466954.35687HepG2DDX59
chr5468602468754+3'-UTR,intron-Proximal3.205353.45841K562HNRNPK
chr5464718464785+3'-UTR,intron-Distal4.228963.79026K562HNRNPM
chr5446299446390+3'-UTR,5'-UTR,CDS3.728286.23335HepG2GRWD1
chr5467103467166+3'-UTR3.980563.02250K562YBX3
chr5464633464706+3'-UTR,intron-Distal3.534895.17284K562TIA1
chr5464347464413+3'-UTR,CDS,intron-Proximal4.104394.69223K562SF3B4
chr5464414464538+3'-UTR,CDS,intron-Proximal3.123506.75486K562UCHL5
chr5446264446438+3'-UTR,5'-UTR,CDS,intron-Proximal3.699587.39702K562RBM15
chr5465832465886+3'-UTR,CDS,intron-Proximal3.266924.74755K562ZNF622
chr5462383462510+3'-UTR,CDS,intron-Proximal3.767529.09021HepG2PRPF8
chr5465166465230+3'-UTR,CDS,intron-Proximal5.389207.91936K562SF3B4
chr5453627453735+CDS3.534384.51896HepG2XPO5
chr5454053454114+CDS3.901373.28989K562RBM15
chr5462317462423+CDS,intron-Proximal3.389774.02291HepG2GRWD1
chr5446382446462+CDS3.098098.73187K562ZNF622
chr5462363462447+CDS,intron-Proximal4.064763.16390K562SRSF1
chr5458117458180+CDS,intron-Distal,intron-Proximal3.440995.06115HepG2PRPF8
chr5462351462422+CDS3.288594.24058K562GRWD1
chr5453821453943+CDS3.573754.83391K562GRWD1
chr5462035462077+CDS,intron-Proximal3.444404.09623HepG2SF3B4
chr5453862453961+CDS4.198834.91614HepG2GRWD1
chr5457103457198+CDS,intron-Distal,intron-Proximal4.156486.95612HepG2PRPF8
chr5453798453927+CDS3.001845.87906K562UCHL5
chr5446381446459+CDS3.955745.42720K562UCHL5
chr5453858453911+CDS3.365833.63681K562RBM15
chr5453811453875+CDS4.047453.70678K562BUD13
chr5457003457094+CDS,intron-Distal,intron-Proximal3.480604.65185K562SRSF1
chr5462027462082+CDS,intron-Proximal4.419429.01749K562SF3B4
chr5453852454004+CDS3.6909211.29508K562ZNF622
chr5446410446502+CDS,intron-Proximal4.033939.70941HepG2PRPF8
chr5466214466321+intron-Distal4.454148.92027K562AKAP8L
chr5461076461121+intron-Distal3.369163.10539K562U2AF2
chr5457121457166+intron-Distal,intron-Proximal6.1996315.31585K562AQR
chr5461068461131+intron-Distal5.201348.16423HepG2U2AF2
chr5460749460839+intron-Distal4.441105.53033K562HNRNPK
chr5466241466352+intron-Distal3.932093.59342K562CSTF2T
chr5464344464395+intron-Proximal4.312884.07325HepG2SF3B4
chr5454166454217+intron-Proximal4.577074.13847K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXOC3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXOC3 is not available on ENCORE database.

  • 55 RBPs can affect the levels of EXOC3.  








The Knockdown/knockout RNA-Seq assay for EXOC3 is not available on ENCORE database.





55 RBPs can affect the gene expression of EXOC3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOC3ENSG00000180104.111018.89090634.871300.682405.417004.70200HepG2AKAP1
EXOC3ENSG00000180104.11713.10630558.402000.352703.072702.26960HepG2AKAP8L
EXOC3ENSG00000180104.11658.78760432.071900.608405.174504.38780HepG2BOP1
EXOC3ENSG00000180104.11539.28470366.565700.556902.535101.80450HepG2CNOT7
EXOC3ENSG00000180104.11636.16080514.027900.307402.635201.81900HepG2DDX19B
EXOC3ENSG00000180104.11611.01230417.491800.549404.263503.43920HepG2DDX21
EXOC3ENSG00000180104.11649.76850531.743100.289102.000401.40990HepG2DKC1
EXOC3ENSG00000180104.11396.42210320.898500.304801.855701.30250HepG2DNAJC2
EXOC3ENSG00000180104.111170.06700948.061200.303401.833601.32310HepG2ETF1
EXOC3ENSG00000180104.11727.66690549.096400.406102.121601.44330HepG2FIP1L1
EXOC3ENSG00000180104.11588.56670449.673200.388201.955301.41120HepG2GPKOW
EXOC3ENSG00000180104.11488.84010326.830500.580704.089303.32680HepG2HNRNPA1
EXOC3ENSG00000180104.11751.71240526.369300.514002.450901.79120HepG2HNRNPK
EXOC3ENSG00000180104.11457.49850361.143700.341102.258401.70530HepG2HNRNPU
EXOC3ENSG00000180104.11804.89260576.610900.481103.073702.40810HepG2NCBP2
EXOC3ENSG00000180104.11488.54160335.144700.543602.237801.45400HepG2PABPC1
EXOC3ENSG00000180104.11446.79790322.109700.472003.528202.70610HepG2PPIL4
EXOC3ENSG00000180104.11769.73470531.267000.534805.890005.15200HepG2PTBP1
EXOC3ENSG00000180104.11743.27900597.651000.314502.120301.58870HepG2PUF60
EXOC3ENSG00000180104.11880.30390634.461700.472407.070306.21120HepG2PUM1
EXOC3ENSG00000180104.11707.35630566.111500.321302.797202.17900HepG2PUS1
EXOC3ENSG00000180104.11777.30220591.241500.394603.534302.93880HepG2NELFE
EXOC3ENSG00000180104.11479.87800339.385500.499603.359002.68960HepG2RPS19
EXOC3ENSG00000180104.11510.95290368.405100.471802.254001.53100HepG2RPS3A
EXOC3ENSG00000180104.11407.59380321.608900.341702.139301.56020HepG2SAFB2
EXOC3ENSG00000180104.11473.18100340.627800.474102.689001.76520HepG2SERBP1
EXOC3ENSG00000180104.11684.18350553.101000.306702.295001.74960HepG2SF3B4
EXOC3ENSG00000180104.11685.39400573.113400.258002.168201.53440HepG2SLBP
EXOC3ENSG00000180104.11472.18580375.040900.332202.392501.78880HepG2SMN1
EXOC3ENSG00000180104.11608.58970425.621300.515802.863601.89020HepG2SMNDC1
EXOC3ENSG00000180104.11328.29250472.62000-0.525702.156201.46990HepG2SNRNP70
EXOC3ENSG00000180104.111077.95290894.946100.268302.409401.93060HepG2SRFBP1
EXOC3ENSG00000180104.11765.01090590.127900.374403.761803.05320HepG2SRSF5
EXOC3ENSG00000180104.11997.87150776.977500.360903.892503.30720HepG2SSB
EXOC3ENSG00000180104.11810.86870671.108300.272802.552701.95130HepG2SUCLG1
EXOC3ENSG00000180104.11493.82740350.883200.492903.720403.15870HepG2TIAL1
EXOC3ENSG00000180104.11752.11500583.926800.365102.763901.89110HepG2TUFM
EXOC3ENSG00000180104.11606.82220469.698100.369401.902101.37080HepG2U2AF1
EXOC3ENSG00000180104.11464.49360329.999000.493102.403301.39130HepG2XPO5
EXOC3ENSG00000180104.11684.05090578.994200.240501.855501.38320HepG2ZNF622
EXOC3ENSG00000180104.11713.01100567.749600.328602.186801.48160K562CPSF6
EXOC3ENSG00000180104.111817.917301339.778900.440207.524006.52050K562DDX47
EXOC3ENSG00000180104.111378.085601144.185100.268202.512801.82180K562EIF2S2
EXOC3ENSG00000180104.11712.56200543.149900.391603.343102.47230K562EIF3G
EXOC3ENSG00000180104.111022.84400858.241100.253002.046201.51100K562FXR1
EXOC3ENSG00000180104.11301.83780472.47000-0.646403.777202.92150K562G3BP2
EXOC3ENSG00000180104.11682.55130542.042900.332401.992201.31500K562GPKOW
EXOC3ENSG00000180104.111011.66450692.056200.547705.655304.83190K562HNRNPC
EXOC3ENSG00000180104.11895.13820660.954300.437503.693002.27510K562IGF2BP3
EXOC3ENSG00000180104.11875.17360681.346100.361102.832501.89810K562MATR3
EXOC3ENSG00000180104.11932.60830663.377800.491305.035104.16230K562PTBP1
EXOC3ENSG00000180104.11820.85540635.948700.368102.579401.76940K562RBM22
EXOC3ENSG00000180104.11828.47410620.044500.418002.857301.45470K562RBM34
EXOC3ENSG00000180104.11861.18610669.269700.363602.386901.38710K562NELFE
EXOC3ENSG00000180104.11945.74450679.951100.475902.876302.04230K562RPS19
EXOC3ENSG00000180104.111166.75760650.362500.8431013.3428011.79110K562SRSF1
EXOC3ENSG00000180104.11850.79440614.295300.469803.827602.55550K562SRSF5
EXOC3ENSG00000180104.11885.77410658.142200.428403.149802.39460K562TARDBP
EXOC3ENSG00000180104.11947.26520634.870100.577206.454505.12610K562TIA1
EXOC3ENSG00000180104.11872.70660623.155000.485804.211702.81710K562TRA2A
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXOC3 is not available on ENCORE database.





14 RBPs can affect the splicing of EXOC3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEEXOC3ENSG00000180104.11chr5+459473459530457120458140462074462185-0.335000.004690.07045excludedK562SF3B4
SEEXOC3ENSG00000180104.11chr5+459473459574458014458140462074462185-0.171000.000750.02482excludedK562AKAP8L
SEEXOC3ENSG00000180104.11chr5+4471324473234462644464644476474478670.243000.001960.04662includedHepG2HNRNPK
SEEXOC3ENSG00000180104.11chr5+4594734595744580144581404620744621850.083000.001430.07463includedHepG2AKAP1
SEEXOC3ENSG00000180104.11chr5+459473459574453511454166462074462185-0.225000.001400.04402excludedK562UTP18
A3SSEXOC3ENSG00000180104.11chr5+459473459574459485459574458014458140-0.180000.000850.04595shorterK562SF3B4
A5SSEXOC3ENSG00000180104.11chr5+4622714626444622714624224644044653870.182000.000000.00000longerK562AQR
RIEXOC3ENSG00000180104.11chr5+464404465387464404464527465225465387-0.116000.001610.08493excludedK562NONO
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.271000.000580.00941includedHepG2PRPF8
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.245000.000010.00017includedK562AGGF1
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.255000.000780.01671includedHepG2G3BP1
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.130000.000720.03827includedK562SBDS
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.354000.000000.00005includedHepG2HNRNPK
RIEXOC3ENSG00000180104.11chr5+4644044653874644044645274652254653870.148000.002180.08131includedHepG2LARP4
RIEXOC3ENSG00000180104.11chr5+464404465387464404464527465225465387-0.140000.003380.05547excludedK562PTBP1
RIEXOC3ENSG00000180104.11chr5+464404465387464404464527465225465387-0.114000.001120.02005excludedK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXOC3 is not avaliable on ENCORE database.