E2F6

General Information

Gene Name       : E2F6
Gene ID             : ENSG00000169016.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: E2F6)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878E2F6ENSG00000169016.167.367.427.39ENCSR000AEF
HepG2E2F6ENSG00000169016.1620.7336.9328.83ENCSR985KAT
K562E2F6ENSG00000169016.1617.8916.5317.21ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for E2F6 is not avaliable on ENCORE database.



Proteins bound to RNA
  • E2F6 RNA is bound by 12 proteins.  







eCLIP assay for E2F6 is not avaliable on ENCORE database.





12 proteins are bound to E2F6 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr21158662411586715-3'-UTR,CDS,intron-Distal4.282514.28193HepG2AQR
chr21158603911586139-3'-UTR,intron-Distal6.6081222.29472K562PUM2
chr21158777711587855-3'-UTR,CDS,intron-Distal,intron-Proximal3.927553.56019HepG2GRWD1
chr21158463311584701-3'-UTR,intron-Distal4.378663.31330K562UPF1
chr21159365811593709-3'-UTR,CDS,intron-Distal,intron-Proximal5.181376.22530K562AQR
chr21160593011605987-5'-UTR,CDS,intron-Distal3.621206.19204K562YBX3
chr21160590411605922-5'-UTR,CDS,intron-Distal3.375067.18673HepG2PRPF8
chr21160589811605987-5'-UTR,CDS,intron-Distal3.587055.82148K562DDX3X
chr21160575911605924-5'-UTR,CDS,intron-Distal5.251116.45599K562PRPF8
chr21160585411605904-5'-UTR,CDS,intron-Distal3.9090417.05206HepG2PRPF8
chr21160611711606273-5'-UTR,intron-Distal,intron-Proximal3.094646.46609HepG2NCBP2
chr21160245011602519-intron-Distal3.830573.71397K562KHSRP
chr21160576711605873-intron-Distal5.0168714.44022HepG2EFTUD2
chr21159026211590348-intron-Distal,intron-Proximal5.166885.54528HepG2QKI
chr21160471411604772-intron-Distal3.439563.35585HepG2QKI
chr21159852811598597-intron-Distal,intron-Proximal3.635234.26114HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for E2F6 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for E2F6 is not available on ENCORE database.

  • 61 RBPs can affect the levels of E2F6.  








The Knockdown/knockout RNA-Seq assay for E2F6 is not available on ENCORE database.





61 RBPs can affect the gene expression of E2F6 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
E2F6ENSG00000169016.12878.38030724.038500.278702.555901.96780HepG2ACO1
E2F6ENSG00000169016.121836.519301071.080700.777808.265907.40030HepG2AKAP1
E2F6ENSG00000169016.121275.83740886.234600.525604.543103.54890HepG2ASCC1
E2F6ENSG00000169016.12588.06040796.88240-0.438402.232001.42460HepG2BCLAF1
E2F6ENSG00000169016.12813.21550467.123900.799709.079708.07310HepG2BOP1
E2F6ENSG00000169016.121145.85600853.598300.424701.942401.30670HepG2CNOT7
E2F6ENSG00000169016.12324.36800428.84500-0.402801.934401.34860HepG2CPSF6
E2F6ENSG00000169016.121518.864501026.025600.565805.208704.37380HepG2DDX3X
E2F6ENSG00000169016.121266.38240881.350700.522803.919503.19390HepG2DDX6
E2F6ENSG00000169016.12426.02650554.28200-0.379702.811902.10500HepG2DNAJC21
E2F6ENSG00000169016.12437.81300847.29010-0.9525010.609009.49510HepG2EIF2S1
E2F6ENSG00000169016.12577.06180436.660700.402102.813501.63390HepG2EIF2S2
E2F6ENSG00000169016.12623.75790388.988200.681205.222404.00900HepG2EIF3D
E2F6ENSG00000169016.121783.78540911.661300.9683010.100008.82660HepG2EIF4B
E2F6ENSG00000169016.122034.986501420.234100.518809.976908.95010HepG2ETF1
E2F6ENSG00000169016.12880.19260707.474000.315002.215601.46840HepG2EWSR1
E2F6ENSG00000169016.121213.08210890.832600.445403.529002.77640HepG2IGF2BP2
E2F6ENSG00000169016.121231.51790945.047100.381902.568301.93490HepG2MAGOH
E2F6ENSG00000169016.121274.58430950.342700.423402.805202.17040HepG2MATR3
E2F6ENSG00000169016.121254.43400972.733700.366802.376201.78680HepG2NCBP2
E2F6ENSG00000169016.121285.35430860.647800.578609.900208.86630HepG2PCBP1
E2F6ENSG00000169016.12373.73580551.48350-0.561305.350404.35490HepG2PPIL4
E2F6ENSG00000169016.121136.24340875.706500.375703.201102.62090HepG2PTBP1
E2F6ENSG00000169016.12894.214901075.59860-0.266401.928101.41770HepG2PUF60
E2F6ENSG00000169016.121787.558801141.741100.6467017.6442016.41370HepG2PUM1
E2F6ENSG00000169016.12975.11610737.473400.402904.996804.21270HepG2PUS1
E2F6ENSG00000169016.121369.96160612.063901.162309.893708.61750HepG2RAVER1
E2F6ENSG00000169016.121631.835201187.070300.459006.923906.19200HepG2RBM22
E2F6ENSG00000169016.121293.03620852.535000.600806.265104.76260HepG2RBM27
E2F6ENSG00000169016.12744.56100974.60620-0.388404.120303.48330HepG2NELFE
E2F6ENSG00000169016.12364.13790550.64220-0.596606.522505.59600HepG2SAFB2
E2F6ENSG00000169016.121278.61730668.972600.934509.142807.86270HepG2SF3A3
E2F6ENSG00000169016.12328.53160459.19060-0.483102.738502.03590HepG2SF3B1
E2F6ENSG00000169016.121179.31060911.785900.371104.116103.41810HepG2SF3B4
E2F6ENSG00000169016.12726.297101031.21980-0.505708.190707.08130HepG2SLBP
E2F6ENSG00000169016.12717.26530510.930200.489302.289001.58060HepG2SNRNP70
E2F6ENSG00000169016.122150.275901340.782800.6813019.3579018.34610HepG2SRFBP1
E2F6ENSG00000169016.121391.79180951.681600.548309.118808.37150HepG2SRSF1
E2F6ENSG00000169016.12696.28200494.091400.494802.683401.69910HepG2SRSF3
E2F6ENSG00000169016.12842.928001061.93180-0.333203.570502.87630HepG2SRSF5
E2F6ENSG00000169016.12988.26860774.221800.352103.785803.16230HepG2SRSF9
E2F6ENSG00000169016.12872.663301164.17040-0.415804.270703.66280HepG2SSB
E2F6ENSG00000169016.121106.11620855.337900.370803.691803.05980HepG2TAF15
E2F6ENSG00000169016.12433.81440600.88440-0.470003.549302.99760HepG2TIAL1
E2F6ENSG00000169016.12473.76480606.16510-0.355502.962702.38350HepG2TRIM56
E2F6ENSG00000169016.12923.32930497.195100.8929010.868409.60280HepG2U2AF1
E2F6ENSG00000169016.121126.61730572.785300.9758023.0465021.56690HepG2UTP3
E2F6ENSG00000169016.12493.45590883.53250-0.840407.522806.34160HepG2XRN2
E2F6ENSG00000169016.12218.75880436.58840-0.9969012.6662011.39970HepG2ZC3H8
E2F6ENSG00000169016.121168.83480652.490600.8409022.0163020.83420HepG2ZNF622
E2F6ENSG00000169016.121965.589001223.292100.684108.659707.71580K562AQR
E2F6ENSG00000169016.12796.52760659.410200.272402.106401.52530K562DDX47
E2F6ENSG00000169016.12711.39600534.034000.413603.036102.17890K562EIF4A3
E2F6ENSG00000169016.12921.95820555.376000.7311011.5239010.37580K562FXR1
E2F6ENSG00000169016.12816.72090528.555900.627704.349103.41890K562G3BP2
E2F6ENSG00000169016.121483.728501138.356700.382203.409102.57190K562GRSF1
E2F6ENSG00000169016.121000.91770727.526100.460203.978102.96410K562MAGOH
E2F6ENSG00000169016.12697.20320518.769100.426404.075503.11030K562MTPAP
E2F6ENSG00000169016.121165.29560601.266800.9545013.3831011.72400K562PRPF8
E2F6ENSG00000169016.12267.21200369.99840-0.469502.163101.37260K562PSIP1
E2F6ENSG00000169016.121041.65270706.806800.559406.614605.62250K562PTBP1
E2F6ENSG00000169016.121788.243101335.398000.421203.545502.62430K562PUF60
E2F6ENSG00000169016.121890.266701419.963300.412605.078903.60090K562PUM1
E2F6ENSG00000169016.12702.03090568.743900.303702.165201.43600K562SF3A3
E2F6ENSG00000169016.12956.27030692.860700.464804.443903.55180K562SRSF1
E2F6ENSG00000169016.12583.89060420.224100.474403.761902.80440K562SYNCRIP
E2F6ENSG00000169016.12690.71550529.387800.383703.009902.17190K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for E2F6 is not available on ENCORE database.





22 RBPs can affect the splicing of E2F6 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.272000.000000.00024includedHepG2G3BP1
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.189000.003900.06203excludedK562SRSF1
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.152000.007050.09875includedHepG2U2AF1
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606272-0.265000.000020.00075excludedHepG2U2AF1
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.126000.004600.08982includedHepG2HNRNPK
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.098000.000290.00499includedHepG2U2AF2
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606272-0.238000.000000.00000excludedHepG2U2AF2
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606272-0.211000.000250.00372excludedK562AQR
SEE2F6ENSG00000169016.12chr2-115901371159019711587881115879001159132711591394-0.249000.000020.00463excludedHepG2SRSF7
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606229-0.410000.000000.00000excludedK562PUS1
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.138000.001430.05497includedHepG2MATR3
SEE2F6ENSG00000169016.12chr2-1159546711595600115937071159392411597304115973590.184000.000140.01758includedHepG2DDX6
SEE2F6ENSG00000169016.12chr2-1159730411597359115937071159392411605897116062720.146000.000100.03839includedK562PPIL4
SEE2F6ENSG00000169016.12chr2-1159013711590219115878811158790011591327115913940.257000.000000.00000includedHepG2SF3A3
SEE2F6ENSG00000169016.12chr2-115913271159139411587752115879001159370711593848-0.698000.000000.00035excludedHepG2SF3A3
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606229-0.213000.000020.00379excludedK562HNRNPUL1
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.167000.000780.03945excludedHepG2PCBP1
SEE2F6ENSG00000169016.12chr2-115901371159021211587752115879001159132711591822-0.428000.000000.00000excludedHepG2SF3B4
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606229-0.334000.001210.03941excludedK562UTP18
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.283000.000000.00039excludedK562TARDBP
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.182000.001440.03600excludedK562RBM15
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606229-0.341000.000040.00210excludedK562AGGF1
SEE2F6ENSG00000169016.12chr2-115973041159735911593707115939241160589711606272-0.176000.001500.05547excludedK562SF3B1
SEE2F6ENSG00000169016.12chr2-1159730411597359115937071159392411605897116062720.282000.000000.00022includedHepG2HNRNPC
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.134000.002630.08113excludedHepG2HNRNPC
SEE2F6ENSG00000169016.12chr2-115954671159560011593707115939241159730411597359-0.254000.000060.00397excludedK562PTBP1
A3SSE2F6ENSG00000169016.12chr2-1158660211586678115866021158664911587752115879670.106000.000000.00000longerK562AQR
A3SSE2F6ENSG00000169016.12chr2-1159177611592007115917761159193211593707115938480.093000.000000.00000longerK562AQR
MXEE2F6ENSG00000169016.12chr2-11593707115939241159546711595600115917761159193211597304115973590.056000.004450.092581includedHepG2MATR3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for E2F6 is not avaliable on ENCORE database.