COMMD4

General Information

Gene Name       : COMMD4
Gene ID             : ENSG00000140365.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: COMMD4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878COMMD4ENSG00000140365.1511.6723.3217.50ENCSR000AEF
HepG2COMMD4ENSG00000140365.1575.5435.1055.32ENCSR985KAT
K562COMMD4ENSG00000140365.1546.3029.5537.92ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for COMMD4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • COMMD4 RNA is bound by 10 proteins.  







eCLIP assay for COMMD4 is not avaliable on ENCORE database.





10 proteins are bound to COMMD4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr157563222975632345+3'-UTR,CDS,intron-Distal,intron-Proximal4.068773.31322HepG2SF3B4
chr157563238775632506+3'-UTR,intron-Distal6.2884512.83360HepG2UPF1
chr157563248375632578+3'-UTR,intron-Distal,intron-Proximal5.525699.06009HepG2LARP4
chr157563246375632580+3'-UTR,intron-Distal,intron-Proximal4.8673010.58184K562UPF1
chr157563207075632220+3'-UTR,CDS,intron-Distal,intron-Proximal4.881607.91835HepG2RPS3
chr157563098075631027+3'-UTR,CDS,intron-Proximal5.425878.55457HepG2PPIG
chr157563236675632455+3'-UTR,intron-Distal4.463544.38135HepG2STAU2
chr157563199075632069+3'-UTR,CDS,intron-Distal,intron-Proximal4.758455.13952K562SF3B4
chr157563237875632464+3'-UTR,intron-Distal4.062225.54091HepG2LARP4
chr157563135575631442+3'-UTR,CDS,intron-Distal,intron-Proximal4.086308.98325HepG2PPIG
chr157563039875630471+CDS,intron-Distal,intron-Proximal3.390813.64037HepG2NCBP2
chr157563040775630471+CDS,intron-Distal3.742723.59112HepG2PPIG
chr157563040175630473+CDS,intron-Distal,intron-Proximal3.5738913.01358K562DDX3X
chr157563048775630569+intron-Distal,intron-Proximal5.109076.10370HepG2PRPF4
chr157563050375630569+intron-Distal,intron-Proximal4.713817.76905K562GTF2F1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for COMMD4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for COMMD4 is not available on ENCORE database.

  • 53 RBPs can affect the levels of COMMD4.  








The Knockdown/knockout RNA-Seq assay for COMMD4 is not available on ENCORE database.





53 RBPs can affect the gene expression of COMMD4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
COMMD4ENSG00000140365.11481.51360321.143200.584302.883901.92290HepG2ABCF1
COMMD4ENSG00000140365.11685.02000487.880400.489502.717802.19030HepG2AKAP1
COMMD4ENSG00000140365.11407.36110941.38260-1.2085028.4620026.67870HepG2AUH
COMMD4ENSG00000140365.11532.69820383.516600.473902.733601.96560HepG2CIRBP
COMMD4ENSG00000140365.11329.31660147.163501.162005.516904.43190HepG2CNOT7
COMMD4ENSG00000140365.11629.04990467.327700.428602.419001.83020HepG2DDX3X
COMMD4ENSG00000140365.11203.77350504.61770-1.3082012.7348011.22160HepG2DDX55
COMMD4ENSG00000140365.11212.86780318.24340-0.580202.683701.59580HepG2AGO1
COMMD4ENSG00000140365.11638.60160426.454700.582403.811503.06650HepG2EIF4A3
COMMD4ENSG00000140365.11386.46190588.25740-0.606106.455705.27180HepG2EIF4G1
COMMD4ENSG00000140365.11419.63310563.51070-0.425302.550901.76700HepG2EIF4G2
COMMD4ENSG00000140365.11637.682501080.83730-0.7612013.8258012.64640HepG2ETF1
COMMD4ENSG00000140365.11748.48430430.359700.798307.555306.45480HepG2FXR1
COMMD4ENSG00000140365.11250.51080136.236300.878704.215802.84600HepG2GRSF1
COMMD4ENSG00000140365.11241.65460547.98490-1.1812017.2371015.30500HepG2HNRNPA2B1
COMMD4ENSG00000140365.11362.35150271.953900.413902.527301.94760HepG2HNRNPU
COMMD4ENSG00000140365.11719.55170430.510400.741006.407205.41890HepG2MAGOH
COMMD4ENSG00000140365.11701.19650443.092200.662105.098904.25090HepG2NCBP2
COMMD4ENSG00000140365.11541.25510426.487000.343702.548301.95970HepG2PCBP1
COMMD4ENSG00000140365.11563.14190433.991800.375702.789602.24030HepG2PTBP1
COMMD4ENSG00000140365.11644.23710463.371300.475302.600601.63960HepG2RBM27
COMMD4ENSG00000140365.11711.38260482.970200.558606.007205.26090HepG2NELFE
COMMD4ENSG00000140365.11634.91950449.859300.497004.856204.06950HepG2RECQL
COMMD4ENSG00000140365.11314.68090429.52780-0.448902.278601.64930HepG2RPLP0
COMMD4ENSG00000140365.11262.25230147.803700.827204.076603.10410HepG2RPS3A
COMMD4ENSG00000140365.11619.74600436.234200.506503.011901.88980HepG2RPS5
COMMD4ENSG00000140365.11231.99330385.02710-0.730904.270803.31670HepG2RRP9
COMMD4ENSG00000140365.11450.43510282.440700.673303.826703.09030HepG2SMN1
COMMD4ENSG00000140365.11787.015501020.33200-0.374604.241003.65950HepG2SRFBP1
COMMD4ENSG00000140365.11754.79650633.765900.252002.017301.46990HepG2SUCLG1
COMMD4ENSG00000140365.11325.37690502.32760-0.626503.831403.05550HepG2SUPV3L1
COMMD4ENSG00000140365.11325.38490165.269000.977202.272401.30610HepG2TBRG4
COMMD4ENSG00000140365.11349.25390264.275900.402102.038001.59540HepG2TIAL1
COMMD4ENSG00000140365.11733.32500551.405100.411203.127402.19330HepG2TUFM
COMMD4ENSG00000140365.11691.71480494.486800.484102.911302.16740HepG2XRN2
COMMD4ENSG00000140365.11250.09900325.59280-0.380602.226801.72110HepG2ZNF622
COMMD4ENSG00000140365.11383.35190291.171900.396702.190801.67580K562AGGF1
COMMD4ENSG00000140365.111093.21310811.913800.429103.508802.09850K562APOBEC3C
COMMD4ENSG00000140365.11865.836601131.46030-0.386003.700702.56710K562CELF1
COMMD4ENSG00000140365.1180.59470256.53340-1.6704010.879007.22130K562DDX55
COMMD4ENSG00000140365.11176.69560278.84720-0.658203.600702.05360K562DHX30
COMMD4ENSG00000140365.11539.04250403.399300.418102.284201.45420K562EFTUD2
COMMD4ENSG00000140365.11124.22930263.72480-1.086007.096405.15640K562FKBP4
COMMD4ENSG00000140365.11645.82000353.798700.8681011.073309.94850K562FXR1
COMMD4ENSG00000140365.1135.48450150.10410-2.0807011.9998010.32030K562G3BP2
COMMD4ENSG00000140365.111149.40990937.899400.293302.166801.49250K562GRSF1
COMMD4ENSG00000140365.11530.36850377.398400.490802.503001.70180K562MAGOH
COMMD4ENSG00000140365.11469.37760335.718500.483402.400401.49240K562PCBP2
COMMD4ENSG00000140365.11480.93500353.885600.442502.990802.15740K562POLR2G
COMMD4ENSG00000140365.11600.70680392.555400.613704.409003.46270K562PRPF8
COMMD4ENSG00000140365.11585.77680366.695900.675704.497903.67090K562PTBP1
COMMD4ENSG00000140365.11581.01980300.506200.951109.357908.40840K562PUS1
COMMD4ENSG00000140365.11521.14340351.400300.568503.124402.22580K562RBM22
COMMD4ENSG00000140365.11189.04600107.734300.811202.974801.93400K562RPS3
COMMD4ENSG00000140365.11236.11300155.973900.598103.103902.19590K562SF3B4
COMMD4ENSG00000140365.11146.00850241.29470-0.724703.745801.82100K562SND1
COMMD4ENSG00000140365.11592.87330363.770500.704604.029603.16880K562TARDBP
COMMD4ENSG00000140365.11651.400601123.52240-0.786404.008602.93640K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for COMMD4 is not available on ENCORE database.





17 RBPs can affect the splicing of COMMD4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECOMMD4ENSG00000140365.11chr15+7563069575630846756304017563047475630986756310260.088000.000980.05909includedHepG2RBM22
SECOMMD4ENSG00000140365.11chr15+756306957563076175630402756304747563098675631026-0.133000.000010.00022excludedK562AQR
SECOMMD4ENSG00000140365.11chr15+7563069575630761756304027563047475630986756317410.122000.000110.00656includedK562FXR1
SECOMMD4ENSG00000140365.11chr15+7563069575630761756304027563047475630986756310260.146000.002450.08671includedHepG2SFPQ
SECOMMD4ENSG00000140365.11chr15+756306957563076175630402756304747563098675631026-0.222000.000510.01300excludedK562U2AF1
SECOMMD4ENSG00000140365.11chr15+756306957563076175630402756304747563098675631026-0.217000.003970.06025excludedK562U2AF2
A3SSCOMMD4ENSG00000140365.11chr15+7563154875631685756316047563168575631196756314450.193000.000000.00000longerK562AQR
A3SSCOMMD4ENSG00000140365.11chr15+7563036275630474756304027563047475628360756284330.072000.000000.00000longerK562AQR
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.290000.000000.00000longerK562AQR
A5SSCOMMD4ENSG00000140365.11chr15+7563026375630488756302637563047475630695756307150.199000.000000.00000longerK562AQR
A5SSCOMMD4ENSG00000140365.11chr15+756304027563076175630402756304747563098675631026-0.179000.000180.00434shorterK562AQR
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.061000.000400.03522longerHepG2SF3B4
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.175000.000140.01588longerHepG2SF3A3
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.122000.000500.04617longerK562RBM15
A5SSCOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630986756310260.260000.000020.00322longerK562FXR1
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.250000.000000.00103longerK562SF3B4
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.121000.000290.03174longerK562AKAP8L
A5SSCOMMD4ENSG00000140365.11chr15+7563069575630846756306957563076175630986756310260.427000.000000.00000longerHepG2U2AF1
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.074000.009450.05326includedK562PUS1
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.202000.000010.00060includedK562HNRNPC
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.571000.000000.00000includedHepG2U2AF2
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.066000.004880.08675includedHepG2UCHL5
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.124000.000260.03562includedHepG2DDX55
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.280000.000000.00000includedHepG2U2AF1
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.395000.000000.00000includedK562U2AF1
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.472000.000000.00000includedK562U2AF2
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.268000.000870.06538includedK562FMR1
RICOMMD4ENSG00000140365.11chr15+7563040275630761756304027563047475630695756307610.250000.000000.00000includedK562AQR
RICOMMD4ENSG00000140365.11chr15+756313257563164875631325756314457563154875631648-0.323000.000230.00174excludedK562AQR
MXECOMMD4ENSG00000140365.11chr15+7563160475631685756320427563221975631325756314457563230575632614-0.262000.002020.090032includedK562LARP4
MXECOMMD4ENSG00000140365.11chr15+75631548756316857563204275632219756313257563144575632305756326140.155000.000000.000021includedK562AQR
MXECOMMD4ENSG00000140365.11chr15+7563040275630474756306957563076175628445756285627563098675631026-0.171000.000060.004042includedHepG2XRN2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for COMMD4 is not avaliable on ENCORE database.