C8orf59

General Information

Gene Name       : C8orf59
Gene ID             : ENSG00000176731.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: C8orf59)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878C8orf59ENSG00000176731.11122.57117.46120.01ENCSR000AEF
HepG2C8orf59ENSG00000176731.1149.74104.1276.93ENCSR985KAT
K562C8orf59ENSG00000176731.11133.60123.25128.43ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for C8orf59 is not avaliable on ENCORE database.



Proteins bound to RNA
  • C8orf59 RNA is bound by 11 proteins.  







eCLIP assay for C8orf59 is not avaliable on ENCORE database.





11 proteins are bound to C8orf59 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr88612675986126867-3'-UTR,CDS,intron-Distal,intron-Proximal5.057756.07551HepG2LARP4
chr88612971686129733-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.6707910.61329K562DDX3X
chr88612971886129740-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.435057.08450HepG2AQR
chr88612676686126822-3'-UTR,CDS,intron-Distal,intron-Proximal5.1350311.14878K562PUM2
chr88613153286131553-5'-UTR,intron-Distal,intron-Proximal5.6009111.11361K562PRPF8
chr88613151086131607-5'-UTR,intron-Distal,intron-Proximal3.625574.44431K562BUD13
chr88613253386132612-5'-UTR,intron-Distal,intron-Proximal3.9146521.55391K562DDX3X
chr88613155386131568-5'-UTR,intron-Distal,intron-Proximal4.160526.42898K562AQR
chr88613147386131516-5'-UTR,intron-Distal,intron-Proximal5.5829925.09248K562AQR
chr88613254586132561-5'-UTR,intron-Distal4.596163.37645HepG2PRPF8
chr88613154286131551-5'-UTR,intron-Distal,intron-Proximal5.0273121.67006K562AQR
chr88613253386132547-5'-UTR,intron-Distal3.441638.42259K562YBX3
chr88613150686131577-5'-UTR,intron-Distal,intron-Proximal5.028435.25202HepG2AQR
chr88613248386132545-5'-UTR,intron-Distal5.4630414.79448HepG2PRPF8
chr88613141386131532-5'-UTR,intron-Distal,intron-Proximal4.0498013.06894K562PRPF8
chr88613156886131622-5'-UTR,intron-Distal,intron-Proximal5.1470412.21485K562AQR
chr88613151686131542-5'-UTR,intron-Distal,intron-Proximal5.2279526.00625K562AQR
chr88612682286126899-CDS,intron-Distal5.290758.31854K562BUD13
chr88612963286129726-CDS,intron-Distal3.551135.15776HepG2BCLAF1
chr88612714986127180-CDS,intron-Distal,intron-Proximal4.140384.48692K562YBX3
chr88612683986126860-CDS,intron-Distal3.974093.43253K562YBX3
chr88612966886129718-CDS,intron-Distal4.161647.75156HepG2AQR
chr88612967086129688-CDS,intron-Distal3.377776.78138K562YBX3
chr88612953986129631-CDS,intron-Distal,intron-Proximal3.378396.04213K562PRPF8
chr88612682986126910-CDS,intron-Distal4.918498.05832K562SF3B4
chr88613242686132483-intron-Distal4.0727610.79642HepG2PRPF8
chr88613240186132531-intron-Distal5.5395120.94138K562PRPF8
chr88613222786132314-intron-Distal3.712105.25185K562PRPF8
chr88612957786129612-intron-Distal,intron-Proximal4.623634.09264K562AQR
chr88613238886132505-intron-Distal6.4010314.17839K562EFTUD2
chr88613240286132509-intron-Distal4.7932028.25269HepG2EFTUD2
chr88613252786132534-intron-Distal5.358797.63570K562AQR
chr88613248786132527-intron-Distal5.1945414.59371K562AQR
chr88612954086129587-intron-Distal,intron-Proximal4.574754.68673K562RBM22
chr88613241486132487-intron-Distal5.1033112.21485K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for C8orf59 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for C8orf59 is not available on ENCORE database.

  • 72 RBPs can affect the levels of C8orf59.  








The Knockdown/knockout RNA-Seq assay for C8orf59 is not available on ENCORE database.





72 RBPs can affect the gene expression of C8orf59 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
C8orf59ENSG00000176731.7170.05880401.98130-1.2411016.4630014.80500HepG2AKAP8L
C8orf59ENSG00000176731.7285.79420661.07850-1.2098014.3788012.71990HepG2ASCC1
C8orf59ENSG00000176731.7615.32460446.118000.463802.725101.79610HepG2BCCIP
C8orf59ENSG00000176731.7514.62160395.071700.381302.175701.48680HepG2CALR
C8orf59ENSG00000176731.7479.95540628.06390-0.388002.107301.42670HepG2CIRBP
C8orf59ENSG00000176731.7284.26640419.99130-0.563102.394401.68600HepG2CNOT7
C8orf59ENSG00000176731.7616.32040748.43750-0.280201.987801.42600HepG2CELF1
C8orf59ENSG00000176731.7621.88940804.72110-0.371803.797402.95220HepG2DAZAP1
C8orf59ENSG00000176731.7378.41400765.36930-1.0162011.1817010.00310HepG2DDX3X
C8orf59ENSG00000176731.7464.10720657.37130-0.502302.380801.80420HepG2DDX6
C8orf59ENSG00000176731.7238.82110327.82190-0.457002.640001.94930HepG2DNAJC21
C8orf59ENSG00000176731.7245.22820324.93960-0.406002.457001.83620HepG2DNAJC2
C8orf59ENSG00000176731.7402.53950632.04300-0.650904.799604.03050HepG2EIF2S1
C8orf59ENSG00000176731.7232.30930331.00470-0.510802.419901.32980HepG2EIF2S2
C8orf59ENSG00000176731.7459.64460698.52830-0.603804.146403.36850HepG2EIF4A3
C8orf59ENSG00000176731.7466.30850680.02670-0.544302.857202.15880HepG2EIF4B
C8orf59ENSG00000176731.7571.93780716.98360-0.326102.537101.95740HepG2ETF1
C8orf59ENSG00000176731.7518.85620704.64520-0.441602.743002.05480HepG2FXR1
C8orf59ENSG00000176731.7406.52130653.73570-0.685405.280204.37370HepG2G3BP1
C8orf59ENSG00000176731.7338.29560471.38450-0.478602.437301.48610HepG2GNB2L1
C8orf59ENSG00000176731.7347.85540452.94500-0.380802.257401.60490HepG2HNRNPF
C8orf59ENSG00000176731.7497.02900661.79400-0.413102.507101.84070HepG2HNRNPK
C8orf59ENSG00000176731.7611.68830733.02930-0.261102.116501.51680HepG2HNRNPL
C8orf59ENSG00000176731.7319.38610446.02750-0.481802.894602.15400HepG2IGF2BP1
C8orf59ENSG00000176731.7311.18040664.53430-1.0946012.3845011.07180HepG2IGF2BP2
C8orf59ENSG00000176731.7479.53710704.89060-0.555803.888503.11210HepG2MAGOH
C8orf59ENSG00000176731.7460.92790708.85860-0.621004.292703.52330HepG2MATR3
C8orf59ENSG00000176731.7376.30300725.57480-0.947209.439008.31020HepG2NCBP2
C8orf59ENSG00000176731.7606.06470797.96160-0.396802.108201.44010HepG2NOL12
C8orf59ENSG00000176731.7450.41790646.25710-0.520803.419302.62180HepG2PABPC4
C8orf59ENSG00000176731.7489.75410678.98370-0.471304.659303.90610HepG2PCBP1
C8orf59ENSG00000176731.7401.55600690.92520-0.7829011.0496010.09800HepG2PTBP1
C8orf59ENSG00000176731.7543.68740808.62420-0.572708.509007.58870HepG2PUM1
C8orf59ENSG00000176731.7575.02780808.02690-0.490804.578803.72700HepG2PUM2
C8orf59ENSG00000176731.7495.40640748.21680-0.594806.128105.25000HepG2QKI
C8orf59ENSG00000176731.7804.79720599.263400.425303.745403.16670HepG2RBM22
C8orf59ENSG00000176731.7536.63180768.90530-0.518905.425004.70770HepG2NELFE
C8orf59ENSG00000176731.7457.98660716.18190-0.645007.780006.82460HepG2RECQL
C8orf59ENSG00000176731.7518.69460719.28150-0.471704.538903.81010HepG2SF3B4
C8orf59ENSG00000176731.7614.05150750.79900-0.290102.098901.67110HepG2SRSF1
C8orf59ENSG00000176731.7438.90870752.11340-0.7770011.5788010.42170HepG2SRSF5
C8orf59ENSG00000176731.7340.52210444.98260-0.386002.370601.72310HepG2SRSF7
C8orf59ENSG00000176731.7470.30100610.83640-0.377203.165502.58340HepG2SRSF9
C8orf59ENSG00000176731.7695.88700587.652600.243801.753501.32240HepG2SSB
C8orf59ENSG00000176731.7613.89880855.34920-0.478505.872705.02820HepG2SUCLG1
C8orf59ENSG00000176731.7289.27970436.65740-0.594002.666902.00130HepG2SUPV3L1
C8orf59ENSG00000176731.7475.90560674.91630-0.504004.829004.12100HepG2TAF15
C8orf59ENSG00000176731.7528.58570744.19860-0.493604.086003.00170HepG2TUFM
C8orf59ENSG00000176731.7510.74090787.73390-0.625104.345303.28150HepG2UBE2L3
C8orf59ENSG00000176731.7433.86420257.967900.750005.955504.83110HepG2UCHL5
C8orf59ENSG00000176731.7647.26430429.840400.590504.462803.54960HepG2XRN2
C8orf59ENSG00000176731.71075.82500836.051300.363703.766903.12320K562AGGF1
C8orf59ENSG00000176731.7619.60590869.93220-0.489604.357203.53090K562AKAP8L
C8orf59ENSG00000176731.71175.949601450.49240-0.302702.052701.53240K562AQR
C8orf59ENSG00000176731.7703.49370937.88350-0.414902.872401.52860K562BCCIP
C8orf59ENSG00000176731.7565.53320906.17430-0.680206.552105.04780K562BCLAF1
C8orf59ENSG00000176731.7446.82980637.47000-0.512604.224503.25370K562CPSF6
C8orf59ENSG00000176731.7481.87220687.46780-0.512604.294302.93940K562CSTF2
C8orf59ENSG00000176731.7789.17810989.95110-0.327003.002502.25830K562EIF2S2
C8orf59ENSG00000176731.7484.15730699.60070-0.531104.399503.36430K562EIF4A3
C8orf59ENSG00000176731.71338.707901693.62910-0.339304.082902.94620K562EIF4G2
C8orf59ENSG00000176731.7869.43000686.894000.339902.305701.53120K562FIP1L1
C8orf59ENSG00000176731.7317.56740545.46450-0.780405.984105.13970K562HNRNPC
C8orf59ENSG00000176731.7788.15920565.009100.480103.190502.18620K562HNRNPM
C8orf59ENSG00000176731.7771.630201076.01020-0.479703.240002.09730K562IGF2BP2
C8orf59ENSG00000176731.71155.95380923.275200.324202.084101.37870K562KIF1C
C8orf59ENSG00000176731.7847.449801131.47960-0.417002.605801.78950K562MAGOH
C8orf59ENSG00000176731.7807.639401129.28070-0.483603.168302.17730K562MATR3
C8orf59ENSG00000176731.7386.37450594.09230-0.620705.293904.05840K562METAP2
C8orf59ENSG00000176731.7633.55300872.14080-0.461105.303804.31820K562NSUN2
C8orf59ENSG00000176731.7515.30780680.00510-0.400102.279201.52430K562PCBP3
C8orf59ENSG00000176731.7387.09670521.59940-0.430202.758101.95760K562POLR2G
C8orf59ENSG00000176731.71126.62900862.855900.384702.439801.92290K562PUS1
C8orf59ENSG00000176731.7662.49090881.79760-0.412504.667003.49050K562SRPK2
C8orf59ENSG00000176731.7497.89000629.53880-0.338502.756601.59470K562SRSF7
C8orf59ENSG00000176731.7832.781001090.72060-0.389302.260101.61640K562TARDBP
C8orf59ENSG00000176731.7701.957101052.08280-0.583804.239603.19450K562TIA1
C8orf59ENSG00000176731.7333.28130499.56460-0.583902.968101.98120K562TRIM56
C8orf59ENSG00000176731.7692.46720924.75490-0.417304.676903.76760K562UPF1
C8orf59ENSG00000176731.7571.98070791.27470-0.468204.042102.97800K562WDR3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for C8orf59 is not available on ENCORE database.





37 RBPs can affect the splicing of C8orf59 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.291000.000000.00000excludedK562SF3B4
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.129000.000000.00034excludedK562PRPF8
SEC8orf59ENSG00000176731.7chr8-8612714986127266861263108612686086129614861297310.068000.000000.00067includedHepG2RBM22
SEC8orf59ENSG00000176731.7chr8-8613144186131592861296148612973186132534861326130.053000.000860.05375includedHepG2RBM22
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326500.289000.000000.00000includedHepG2U2AF1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.391000.000000.00000excludedHepG2U2AF1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.111000.000770.06760excludedHepG2PRPF8
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.099000.000010.00102excludedK562AKAP8L
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.082000.000150.00550excludedHepG2HNRNPK
SEC8orf59ENSG00000176731.7chr8-861314648613159286129614861297318613253486132650-0.077000.000110.00444excludedHepG2HNRNPK
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.209000.000000.00045includedHepG2DDX59
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.099000.000590.05186includedHepG2QKI
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.209000.000000.00001includedHepG2U2AF2
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.723000.000000.00000excludedHepG2U2AF2
SEC8orf59ENSG00000176731.7chr8-861271498612726686126790861268608612961486129731-0.171000.000000.00000excludedK562AQR
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.090000.000000.00105includedHepG2SRSF7
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.054000.000260.04661excludedK562DROSHA
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.177000.000000.00059includedHepG2FAM120A
SEC8orf59ENSG00000176731.7chr8-8613146486131589861296148612973186132534861325820.091000.000110.02993includedHepG2UCHL5
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.136000.000000.00022includedHepG2TIA1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.275000.000000.00000excludedHepG2BCLAF1
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.075000.000290.02882includedK562SUPV3L1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.101000.000490.04308excludedK562SUPV3L1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.169000.000000.00000excludedK562PUS1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.080000.000260.02088excludedHepG2NCBP2
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.066000.000070.00631includedHepG2PTBP1
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326500.300000.000000.00017includedHepG2FTO
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.096000.000790.04318excludedK562EFTUD2
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.079000.000210.01244excludedHepG2MATR3
SEC8orf59ENSG00000176731.7chr8-861314648613158986129614861297318613253486132582-0.063000.000110.00771excludedHepG2MATR3
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.140000.000000.00000includedK562U2AF1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.490000.000000.00000excludedK562U2AF1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.233000.000000.00000excludedK562HNRNPL
SEC8orf59ENSG00000176731.7chr8-861315518613159286129614861297318613253486132604-0.055000.000270.02365excludedK562HNRNPL
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326500.113000.000120.05048includedHepG2XPO5
SEC8orf59ENSG00000176731.7chr8-861271498612726686126736861268608612961486129731-0.154000.000000.00003excludedHepG2SF3A3
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.055000.000360.03212excludedK562HNRNPUL1
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.185000.000000.00000includedHepG2SUPV3L1
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.207000.000000.00000includedHepG2PCBP1
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.066000.000020.00194includedHepG2SF3B4
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.073000.000860.04125excludedHepG2SF3B4
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.106000.000020.00542includedHepG2TAF15
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.217000.000000.00000includedK562U2AF2
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.722000.000000.00000excludedK562U2AF2
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.170000.000000.00000includedK562TARDBP
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.166000.000000.00000excludedK562TARDBP
SEC8orf59ENSG00000176731.7chr8-861315518613159286129614861297318613253486132604-0.058000.000020.00144excludedK562HNRNPU
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.095000.000000.00027excludedK562RBM15
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.107000.000110.00688excludedK562SF3B1
SEC8orf59ENSG00000176731.7chr8-861271498612726686126310861268608612961486129731-0.206000.000000.00000excludedK562HNRNPK
SEC8orf59ENSG00000176731.7chr8-861314648613159286129499861297318613253486132650-0.138000.000000.00000excludedHepG2HNRNPU
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.061000.003080.09054includedHepG2HNRNPC
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326130.224000.000000.00000includedHepG2SRSF9
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326500.115000.000070.02508includedHepG2FUS
SEC8orf59ENSG00000176731.7chr8-8613146486131592861296148612973186132534861326500.158000.000000.00001includedHepG2KHSRP
SEC8orf59ENSG00000176731.7chr8-8613155186131592861296148612973186132534861326040.053000.001960.06637includedK562PTBP1
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.176000.000890.08357shorterHepG2SRSF9
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.191000.000530.04907shorterHepG2RBM22
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.200000.000270.02703shorterHepG2SF3B4
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.206000.000030.02743shorterHepG2KHSRP
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.277000.000010.00415shorterHepG2SRSF7
A5SSC8orf59ENSG00000176731.7chr8-861314648613159286131551861315928612961486129731-0.214000.000130.03341shorterHepG2PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for C8orf59 is not avaliable on ENCORE database.