ANGPT1

General Information

Gene Name       : ANGPT1
Gene ID             : ENSG00000154188.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ANGPT1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ANGPT1ENSG00000154188.90.000.000.00ENCSR000AEF
HepG2ANGPT1ENSG00000154188.90.000.000.00ENCSR985KAT
K562ANGPT1ENSG00000154188.929.5528.3828.96ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ANGPT1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ANGPT1 RNA is bound by 13 proteins.  







eCLIP assay for ANGPT1 is not avaliable on ENCORE database.





13 proteins are bound to ANGPT1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr8108262859108262905-3'-UTR,intron-Distal4.240315.97140K562PUM2
chr8108261960108261980-3'-UTR,intron-Distal5.9328318.31507K562PABPC4
chr8108262201108262256-3'-UTR,intron-Distal3.722193.37083K562UPF1
chr8108262483108262557-3'-UTR,intron-Distal4.493893.02060K562LIN28B
chr8108262107108262246-3'-UTR,intron-Distal3.725157.91135K562FAM120A
chr8108263404108263509-3'-UTR,intron-Distal3.240593.78871K562IGF2BP1
chr8108261936108261960-3'-UTR,intron-Distal6.2721115.60343K562PABPC4
chr8108261980108261999-3'-UTR,intron-Distal4.583265.63156K562PABPC4
chr8108348356108348483-5'-UTR,CDS,intron-Distal,intron-Proximal3.064395.43721K562ZNF622
chr8108264168108264244-CDS,intron-Distal4.538305.64683K562YBX3
chr8108322899108322953-intron-Distal4.136304.24993K562HNRNPL
chr8108291902108291984-intron-Distal4.461485.29390K562TARDBP
chr8108341885108341940-intron-Distal4.216044.71638K562HNRNPL
chr8108302440108302514-intron-Distal3.907637.33269K562PTBP1
chr8108323379108323414-intron-Distal4.4461813.44088K562AGGF1
chr8108336334108336382-intron-Distal4.162069.80509K562HNRNPL
chr8108313621108313726-intron-Distal3.550874.92145K562HNRNPL
chr8108295844108295937-intron-Distal3.566205.37900K562TARDBP
chr8108323242108323307-intron-Distal3.4402711.84067K562AGGF1
chr8108323038108323111-intron-Distal3.297133.06644K562GTF2F1
chr8108323039108323192-intron-Distal6.0897385.09587K562AGGF1
chr8108323289108323373-intron-Distal4.3686314.62564K562HNRNPL
chr8108323093108323189-intron-Distal6.4339922.39437K562HNRNPL
chr8108345476108345548-intron-Distal3.793324.22415K562PTBP1
chr8108323307108323379-intron-Distal5.5718829.55466K562AGGF1
chr8108323111108323177-intron-Distal4.520865.23961K562GTF2F1
chr8108323373108323413-intron-Distal3.221365.38148K562HNRNPL
chr8108323042108323093-intron-Distal4.924608.84337K562HNRNPL
chr8108346040108346139-intron-Distal6.2705316.72121K562PTBP1
chr8108333180108333245-intron-Distal4.182094.39969K562TARDBP
chr8108298136108298252-intron-Distal4.7377318.18078K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ANGPT1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ANGPT1 is not available on ENCORE database.

  • 67 RBPs can affect the levels of ANGPT1.  








The Knockdown/knockout RNA-Seq assay for ANGPT1 is not available on ENCORE database.





67 RBPs can affect the gene expression of ANGPT1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ANGPT1ENSG00000154188.516.717100.0000099999.999904.409503.54880HepG2HNRNPC
ANGPT1ENSG00000154188.5959.81780568.219700.756209.416707.23960K562AARS
ANGPT1ENSG00000154188.5590.69520785.21050-0.410704.158903.48820K562AGGF1
ANGPT1ENSG00000154188.5664.16150862.75250-0.377402.928601.90900K562AKAP8
ANGPT1ENSG00000154188.5422.04910695.26740-0.720209.263706.75760K562BCCIP
ANGPT1ENSG00000154188.5531.90640671.93570-0.337202.822101.85210K562BCLAF1
ANGPT1ENSG00000154188.5707.998301191.85820-0.751407.986705.93130K562CIRBP
ANGPT1ENSG00000154188.5658.11770953.01880-0.534203.037201.51940K562CKAP4
ANGPT1ENSG00000154188.5589.46340949.78850-0.688203.858502.56470K562CNOT7
ANGPT1ENSG00000154188.5332.48500509.76350-0.616505.318403.78350K562CSTF2
ANGPT1ENSG00000154188.51499.600401892.37730-0.335602.956601.94950K562CELF1
ANGPT1ENSG00000154188.5475.76720712.92900-0.583506.072804.25720K562EIF2S1
ANGPT1ENSG00000154188.52074.26610886.331901.2266041.2222039.08970K562EIF2S2
ANGPT1ENSG00000154188.5585.96960803.92940-0.456203.470002.58420K562EIF3G
ANGPT1ENSG00000154188.51097.546401539.35960-0.488004.840503.61530K562EIF4G2
ANGPT1ENSG00000154188.5449.62570591.89390-0.396602.815301.51010K562EWSR1
ANGPT1ENSG00000154188.5349.32500491.03500-0.491303.522002.07070K562EXOSC5
ANGPT1ENSG00000154188.5464.51800714.76910-0.621705.670704.42920K562FIP1L1
ANGPT1ENSG00000154188.51152.32680539.583901.094509.192506.96030K562FKBP4
ANGPT1ENSG00000154188.5530.20900710.69070-0.422703.604402.04540K562FUS
ANGPT1ENSG00000154188.5897.12980705.158600.347303.284602.63370K562FXR1
ANGPT1ENSG00000154188.51019.33310787.001100.373101.949501.36830K562G3BP2
ANGPT1ENSG00000154188.5479.40920689.53980-0.524405.236303.69560K562GLRX3
ANGPT1ENSG00000154188.5299.40140698.87030-1.222904.602403.58190K562GPKOW
ANGPT1ENSG00000154188.5673.225401181.28770-0.811204.710803.72490K562GRSF1
ANGPT1ENSG00000154188.5505.62720860.13040-0.766505.568804.06750K562HNRNPA1
ANGPT1ENSG00000154188.5315.08560622.04860-0.981307.191506.27310K562HNRNPC
ANGPT1ENSG00000154188.5350.63340555.35710-0.663504.571503.05810K562HNRNPF
ANGPT1ENSG00000154188.5568.17590952.45220-0.745309.666608.01220K562HNRNPU
ANGPT1ENSG00000154188.5662.761601111.51300-0.746006.892104.98160K562IGF2BP2
ANGPT1ENSG00000154188.5808.002401130.78220-0.484904.101902.58630K562IGF2BP3
ANGPT1ENSG00000154188.5334.24570630.61590-0.915904.655102.65360K562LIN28B
ANGPT1ENSG00000154188.5689.790701166.42080-0.757907.801706.15090K562MATR3
ANGPT1ENSG00000154188.5366.25640682.15050-0.897203.083802.15740K562METAP2
ANGPT1ENSG00000154188.5370.52510724.96470-0.9683016.5837014.83050K562MTPAP
ANGPT1ENSG00000154188.5907.69710680.877300.414702.096001.35040K562NAA15
ANGPT1ENSG00000154188.5494.77480805.48120-0.7031012.1213010.71110K562NSUN2
ANGPT1ENSG00000154188.5587.49740912.46870-0.635203.674102.23050K562PABPC1
ANGPT1ENSG00000154188.5814.138501142.14840-0.488404.756202.94520K562PCBP1
ANGPT1ENSG00000154188.5349.97370624.59730-0.835707.363106.00540K562PCBP3
ANGPT1ENSG00000154188.5255.94210479.11510-0.904607.954406.61760K562POLR2G
ANGPT1ENSG00000154188.5569.29100811.35450-0.511204.194903.15660K562PPIG
ANGPT1ENSG00000154188.5404.09660557.69470-0.464802.104001.32630K562PSIP1
ANGPT1ENSG00000154188.5302.21160508.64580-0.751104.777403.47220K562RCC2
ANGPT1ENSG00000154188.5549.73780799.39670-0.540204.896302.51010K562RECQL
ANGPT1ENSG00000154188.5603.57020791.68890-0.391403.267801.54650K562RPS10
ANGPT1ENSG00000154188.5567.02930865.14610-0.609503.394101.67350K562SBDS
ANGPT1ENSG00000154188.5597.64150794.83370-0.411403.715702.77790K562SF3A3
ANGPT1ENSG00000154188.5664.38540818.57060-0.301102.213001.44970K562SF3B4
ANGPT1ENSG00000154188.5331.22170482.20110-0.541802.742501.72340K562SRFBP1
ANGPT1ENSG00000154188.5675.06810814.32690-0.270602.281901.42320K562SRPK2
ANGPT1ENSG00000154188.5643.110901113.03980-0.791406.999705.88410K562SRSF1
ANGPT1ENSG00000154188.5692.976101051.02900-0.600904.417203.03810K562SRSF5
ANGPT1ENSG00000154188.5683.27780480.526700.507802.386601.62480K562SYNCRIP
ANGPT1ENSG00000154188.5771.578601126.60220-0.546103.483702.68600K562TARDBP
ANGPT1ENSG00000154188.5804.157401086.70000-0.434403.532602.59130K562TIA1
ANGPT1ENSG00000154188.5233.26610536.43070-1.201409.412207.60460K562TIAL1
ANGPT1ENSG00000154188.5797.264101066.06020-0.419203.390402.15610K562TRA2A
ANGPT1ENSG00000154188.5250.53470569.68910-1.1852010.644708.50170K562TRIM56
ANGPT1ENSG00000154188.5544.57200763.11600-0.486803.173601.99050K562U2AF1
ANGPT1ENSG00000154188.5493.18950788.04900-0.676108.147606.75450K562U2AF2
ANGPT1ENSG00000154188.5688.44670854.07030-0.311002.807902.08470K562UPF1
ANGPT1ENSG00000154188.5622.10180826.68070-0.410202.585901.42840K562UTP3
ANGPT1ENSG00000154188.5437.04990730.79840-0.741708.610107.02870K562WDR3
ANGPT1ENSG00000154188.5510.31390759.96310-0.574507.889006.52970K562WDR43
ANGPT1ENSG00000154188.51193.673701586.46000-0.410403.579902.10030K562WRN
ANGPT1ENSG00000154188.5392.09050555.20170-0.501803.080101.78400K562XRN2
ANGPT1ENSG00000154188.5800.169401508.76810-0.9150011.320609.44250K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ANGPT1 is not available on ENCORE database.





10 RBPs can affect the splicing of ANGPT1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.153000.000090.05153excludedK562TIA1
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.136000.000480.07118excludedK562MATR3
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.159000.000100.03199excludedK562PCBP1
SEANGPT1ENSG00000154188.5chr8-1082885831082887031082764481082765791082969091082970760.103000.000200.00311includedK562AQR
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.459000.000000.00000excludedK562AQR
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.222000.000210.00452excludedK562PUS1
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.229000.001350.02870excludedK562U2AF1
SEANGPT1ENSG00000154188.5chr8-108315467108315595108306163108306265108348377108348499-0.237000.001540.02832excludedK562U2AF2
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.165000.000020.03477excludedK562TRA2A
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.157000.000020.00177excludedK562HNRNPK
SEANGPT1ENSG00000154188.5chr8-108296909108297076108276448108276579108306163108306265-0.163000.000030.00270excludedK562PTBP1
A3SSANGPT1ENSG00000154188.5chr8-1082969091082971061082969091082970761083061631083063830.105000.000000.00005longerK562AQR
A3SSANGPT1ENSG00000154188.5chr8-1083061631083063021083061631083062651083154671083155950.058000.010530.05526longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ANGPT1 is not avaliable on ENCORE database.