WDR70

General Information

Gene Name       : WDR70
Gene ID             : ENSG00000082068.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WDR70)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR70ENSG00000082068.818.8921.6020.25ENCSR000AEF
HepG2WDR70ENSG00000082068.815.4919.6517.57ENCSR985KAT
K562WDR70ENSG00000082068.824.5426.0825.31ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR70 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR70 RNA is bound by 27 proteins.  







eCLIP assay for WDR70 is not avaliable on ENCORE database.





27 proteins are bound to WDR70 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr53737940837379492+5'-UTR,CDS4.9724621.42682K562ZNF622
chr53737941737379488+5'-UTR,CDS4.372204.67744K562BUD13
chr53737943237379486+5'-UTR,CDS3.478933.86355HepG2PPIG
chr53747998037480095+CDS,intron-Proximal3.050894.10087HepG2BCLAF1
chr53743802337438084+CDS,intron-Proximal5.076437.35950HepG2PPIG
chr53738174037381787+CDS3.026883.71797HepG2BCLAF1
chr53739214737392203+CDS4.576285.13243HepG2GRWD1
chr53743802337438086+CDS,intron-Proximal3.276653.85473K562GRWD1
chr53739658937396674+CDS,intron-Proximal3.720393.87469HepG2BCLAF1
chr53747993437479969+CDS,intron-Proximal3.300625.79905HepG2BCLAF1
chr53739658337396676+CDS,intron-Proximal4.081223.61393K562CPSF6
chr53739665837396673+CDS,intron-Proximal4.870764.48364K562DDX24
chr53747993437479960+CDS,intron-Proximal5.733217.72885K562DDX24
chr53748001337480090+CDS,intron-Proximal3.636025.21950K562DDX24
chr53744341937443476+CDS,intron-Proximal4.1894813.21742K562DDX24
chr53743802337438084+CDS,intron-Proximal5.865747.12981K562DDX24
chr53739210137392114+CDS,intron-Proximal4.192303.17814K562PUM1
chr53739657437396635+CDS3.455599.32936K562ZNF622
chr53739647537396529+CDS,intron-Proximal3.211699.80632K562UCHL5
chr53743802037438080+CDS,intron-Proximal3.155724.56061K562BUD13
chr53739221137392224+CDS,intron-Proximal4.166568.21285K562ZNF622
chr53739659137396683+CDS,intron-Proximal4.679745.29009HepG2TRA2A
chr53744340137443432+CDS3.406144.88483K562ZNF622
chr53739214237392225+CDS,intron-Proximal3.6731411.39812HepG2PPIG
chr53747993537479949+CDS,intron-Proximal4.357876.14226K562ZNF622
chr53739220337392224+CDS,intron-Proximal4.344335.42152HepG2GRWD1
chr53751669037516735+CDS,intron-Proximal4.8344813.90015K562AQR
chr53743802137438066+CDS,intron-Proximal3.081606.53346K562ZNF622
chr53770312837703190+CDS,intron-Proximal3.606333.01531K562YBX3
chr53739647537396555+CDS,intron-Proximal3.524896.28230HepG2PPIG
chr53739211937392213+CDS3.2727217.40255K562UCHL5
chr53747999237480090+CDS,intron-Proximal3.029953.89662K562BUD13
chr53739221337392223+CDS,intron-Proximal3.9109910.80378K562UCHL5
chr53751661537516662+CDS,intron-Proximal3.775883.95301K562ZNF622
chr53739647437396554+CDS,intron-Proximal4.7582816.89898HepG2BCLAF1
chr53739647437396539+CDS,intron-Proximal3.3668010.59455K562DDX24
chr53739220937392223+CDS,intron-Proximal4.281399.39582HepG2BCLAF1
chr53739211437392199+CDS3.9847811.81778K562PUM1
chr53744346837443485+CDS,intron-Proximal4.461597.53358HepG2BCLAF1
chr53744343337443468+CDS4.080348.51432HepG2BCLAF1
chr53743803337438085+CDS,intron-Proximal3.754074.76554HepG2BCLAF1
chr53739647437396514+CDS,intron-Proximal3.546535.10069HepG2GRWD1
chr53770112337701217+CDS,intron-Proximal3.966595.18845HepG2U2AF2
chr53744343237443475+CDS,intron-Proximal4.0521510.43407K562ZNF622
chr53739212337392225+CDS,intron-Proximal3.695054.06415K562TRA2A
chr53739210337392228+CDS,intron-Proximal3.7199724.76356K562DDX24
chr53760522937605319+CDS3.720584.06757K562UCHL5
chr53739666137396673+CDS,intron-Proximal3.046355.26696K562UCHL5
chr53739658237396658+CDS4.117285.20093K562DDX24
chr53739212937392224+CDS,intron-Proximal3.355535.62323K562RBFOX2
chr53739210137392211+CDS,intron-Proximal4.0691623.92771K562ZNF622
chr53747998437480084+CDS3.3981210.46214K562ZNF622
chr53743802137438081+CDS,intron-Proximal3.984919.16086K562UCHL5
chr53739212837392209+CDS5.5015119.63052HepG2BCLAF1
chr53739647537396494+CDS,intron-Proximal3.665848.43531K562ZNF622
chr53760519837605312+CDS5.460649.78817HepG2BCLAF1
chr53748917137489313+intron-Distal3.265933.42785HepG2HNRNPM
chr53768208137682132+intron-Distal4.834696.08869K562EXOSC5
chr53749761137497663+intron-Distal6.1800018.52659HepG2PCBP2
chr53767296237673027+intron-Distal4.641543.85055HepG2XPO5
chr53753053837530630+intron-Distal4.667985.12361K562EXOSC5
chr53764310937643175+intron-Distal4.410703.89080K562EXOSC5
chr53751031437510432+intron-Distal7.1088819.57000K562QKI
chr53762985537629961+intron-Distal4.051783.92684K562KHSRP
chr53768457837684632+intron-Distal4.167983.89080K562EXOSC5
chr53741557137415646+intron-Distal4.185113.57329K562XRN2
chr53768494537685008+intron-Distal4.129663.71802K562RBFOX2
chr53762764337627674+intron-Distal4.097303.01456K562EXOSC5
chr53762898737629045+intron-Distal4.315324.10336HepG2SUGP2
chr53740216537402248+intron-Distal3.854873.28841HepG2PTBP1
chr53752981337529901+intron-Distal4.283293.01445K562EXOSC5
chr53768190337681941+intron-Distal4.957256.08869K562EXOSC5
chr53766530937665383+intron-Distal4.184124.07628HepG2PTBP1
chr53768299237683046+intron-Distal5.5605810.01162K562EXOSC5
chr53765428737654342+intron-Distal4.064763.30696K562EXOSC5
chr53753033437530425+intron-Distal5.138548.04096K562EXOSC5
chr53749755637497611+intron-Distal5.402707.89532HepG2PCBP2
chr53740217237402267+intron-Distal3.862383.76275K562PTBP1
chr53768284137682905+intron-Distal5.007027.06134K562EXOSC5
chr53762661737626747+intron-Distal5.3784110.20783HepG2HNRNPM
chr53770102137701074+intron-Distal,intron-Proximal4.116469.23478K562PTBP1
chr53749760837497722+intron-Distal3.830323.14687K562CSTF2T
chr53757622237576357+intron-Distal3.587323.51820HepG2PCBP2
chr53762802037628082+intron-Distal4.180033.84389HepG2SUGP2
chr53763051537630582+intron-Distal4.139243.51329HepG2MATR3
chr53751032637510448+intron-Distal6.7299828.17729HepG2QKI
chr53763051337630545+intron-Distal3.685053.04224HepG2SUGP2
chr53739989737400003+intron-Distal3.762203.08314K562TARDBP
chr53765520737655255+intron-Distal3.406534.36650HepG2SUGP2
chr53755944537559560+intron-Distal5.527107.91717K562PTBP1
chr53763021537630309+intron-Distal3.593615.13070HepG2HNRNPM
chr53755944237559521+intron-Distal3.802646.24904HepG2PTBP1
chr53765517637655253+intron-Distal4.706635.37222HepG2MATR3
chr53764435137644397+intron-Distal4.196273.30687K562EXOSC5
chr53763026237630356+intron-Distal3.053544.24063HepG2SUGP2
chr53749757537497711+intron-Distal4.172057.56833K562ILF3
chr53763049937630590+intron-Distal3.696274.31658K562EXOSC5
chr53768508037685145+intron-Distal4.449055.52571HepG2RBFOX2
chr53753310337533188+intron-Distal4.614274.02846K562HNRNPM
chr53751674137516798+intron-Distal,intron-Proximal5.747599.41643K562AQR
chr53753309337533180+intron-Distal4.304824.48560K562EXOSC5
chr53762670637626758+intron-Distal4.597183.53404K562HNRNPM
chr53768490937685007+intron-Distal3.976765.82228HepG2RBFOX2
chr53770102537701071+intron-Distal,intron-Proximal3.792113.09122HepG2PTBP1
chr53768543737685506+intron-Distal3.345823.76326HepG2RBFOX2
chr53760703837607095+intron-Distal4.864124.57427HepG2PCBP2
chr53757614337576222+intron-Distal4.063673.23894HepG2PCBP2
chr53768200037682056+intron-Distal5.088417.71416K562EXOSC5
chr53768184737681887+intron-Distal4.546025.44433K562EXOSC5
chr53748919237489347+intron-Distal4.667504.51377K562HNRNPM
chr53765517237655258+intron-Distal4.040306.71225K562EXOSC5
chr53754334537543450+intron-Distal4.070523.49011K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR70 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR70 is not available on ENCORE database.

  • 57 RBPs can affect the levels of WDR70.  








The Knockdown/knockout RNA-Seq assay for WDR70 is not available on ENCORE database.





57 RBPs can affect the gene expression of WDR70 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR70ENSG00000082068.4289.65750419.51260-0.534402.829501.78120HepG2AKAP8
WDR70ENSG00000082068.4321.39040473.90390-0.560303.705003.02340HepG2BOP1
WDR70ENSG00000082068.4473.71860596.42840-0.332302.380301.77610HepG2CELF1
WDR70ENSG00000082068.4483.76840386.178900.324902.407801.62410HepG2DDX19B
WDR70ENSG00000082068.4360.23500524.06700-0.540802.992102.35190HepG2DDX6
WDR70ENSG00000082068.4245.27440353.84710-0.528703.504502.71990HepG2DNAJC21
WDR70ENSG00000082068.4304.64320503.82780-0.725805.216604.41760HepG2EIF2S1
WDR70ENSG00000082068.4390.95140606.07750-0.632505.055403.97350HepG2EIF4G2
WDR70ENSG00000082068.4363.34590521.12630-0.520303.040102.34430HepG2G3BP1
WDR70ENSG00000082068.4303.87300398.63510-0.391602.675901.71250HepG2HDGF
WDR70ENSG00000082068.4205.42640397.37700-0.951907.584906.48350HepG2HNRNPC
WDR70ENSG00000082068.4203.34030318.53580-0.647602.946801.57210HepG2ILF3
WDR70ENSG00000082068.4339.42630532.79430-0.650503.653302.48260HepG2KHSRP
WDR70ENSG00000082068.4425.25310561.94390-0.402102.092601.51920HepG2MAGOH
WDR70ENSG00000082068.4396.98310578.41290-0.543003.422502.72160HepG2NCBP2
WDR70ENSG00000082068.4362.87970515.14070-0.505503.010702.25920HepG2PABPC4
WDR70ENSG00000082068.4405.72700568.77870-0.487404.619803.86990HepG2PCBP1
WDR70ENSG00000082068.4255.49220396.56140-0.634303.528101.63380HepG2PHF6
WDR70ENSG00000082068.4367.88620578.73220-0.653606.783606.00190HepG2PTBP1
WDR70ENSG00000082068.4313.16260607.04500-0.9549011.1146010.02770HepG2PUF60
WDR70ENSG00000082068.4432.92880644.40240-0.573807.348406.47700HepG2PUM1
WDR70ENSG00000082068.4282.15130438.95090-0.637602.568801.88850HepG2RAVER1
WDR70ENSG00000082068.4766.16780623.583400.297002.262501.78090HepG2RBM22
WDR70ENSG00000082068.4324.43050568.86840-0.810208.458907.32900HepG2RBM25
WDR70ENSG00000082068.4516.68820644.09110-0.318002.338901.83360HepG2NELFE
WDR70ENSG00000082068.4374.43890543.90750-0.538602.679302.01640HepG2SF3A3
WDR70ENSG00000082068.4376.08290602.57320-0.680107.846706.93180HepG2SF3B4
WDR70ENSG00000082068.4328.51610518.35820-0.658003.274202.42090HepG2SNRNP70
WDR70ENSG00000082068.4463.30410599.36530-0.371502.907802.26660HepG2SRSF5
WDR70ENSG00000082068.4400.46470505.22660-0.335302.180601.55440HepG2SRSF7
WDR70ENSG00000082068.4325.76110511.66300-0.651407.162706.34920HepG2SRSF9
WDR70ENSG00000082068.4436.07280565.27280-0.374402.771802.21120HepG2TAF15
WDR70ENSG00000082068.4345.34630458.73470-0.409602.144601.49450HepG2TARDBP
WDR70ENSG00000082068.4413.01020519.45460-0.330802.029501.31120HepG2TIA1
WDR70ENSG00000082068.4269.85240387.00480-0.520204.066603.40950HepG2TRIM56
WDR70ENSG00000082068.4465.59530593.05290-0.349102.130101.37160HepG2TUFM
WDR70ENSG00000082068.4285.51090425.84890-0.576803.668702.94920HepG2U2AF1
WDR70ENSG00000082068.4325.71540649.49030-0.995702.887701.87720HepG2U2AF2
WDR70ENSG00000082068.4360.62660482.36430-0.419603.260502.51350HepG2UPF1
WDR70ENSG00000082068.41090.285201367.88940-0.327202.087301.56370K562AQR
WDR70ENSG00000082068.41171.63850969.196200.273602.310001.48290K562ATP5C1
WDR70ENSG00000082068.41576.979901327.831100.248002.733702.08630K562DDX47
WDR70ENSG00000082068.41195.60480994.039900.266302.307901.51790K562DKC1
WDR70ENSG00000082068.4519.91400732.05240-0.493703.653902.59270K562EFTUD2
WDR70ENSG00000082068.4582.87110783.68000-0.427102.538701.55170K562EIF3D
WDR70ENSG00000082068.4508.61560683.44590-0.426303.038202.18050K562EIF4A3
WDR70ENSG00000082068.4701.72880915.77870-0.384102.685501.84420K562FMR1
WDR70ENSG00000082068.4300.04010828.09000-1.4646026.9367025.15710K562HNRNPC
WDR70ENSG00000082068.41037.60960798.478000.377802.456001.30180K562HNRNPK
WDR70ENSG00000082068.41659.704801343.310400.305002.150501.44600K562HSPD1
WDR70ENSG00000082068.4540.58100808.47810-0.580705.304803.24730K562PHF6
WDR70ENSG00000082068.4498.17420742.47130-0.575704.748403.51920K562PSIP1
WDR70ENSG00000082068.4577.61840816.28540-0.499004.873404.01550K562PTBP1
WDR70ENSG00000082068.41616.891702016.58650-0.318703.494302.41650K562PUM2
WDR70ENSG00000082068.4468.78200731.69360-0.642306.450704.33270K562RBM25
WDR70ENSG00000082068.4500.35630677.41770-0.437103.275502.19510K562RCC2
WDR70ENSG00000082068.4849.882101104.29160-0.377804.000603.02820K562SF3A3
WDR70ENSG00000082068.4467.88030802.13910-0.7777010.763209.02390K562SF3B4
WDR70ENSG00000082068.4651.651901070.36830-0.715902.969201.59740K562SFPQ
WDR70ENSG00000082068.4456.80860600.25970-0.394002.342301.38590K562SRSF4
WDR70ENSG00000082068.4496.08460689.56860-0.475103.035001.96820K562SUPV3L1
WDR70ENSG00000082068.4580.63490809.89890-0.480103.704902.88150K562TARDBP
WDR70ENSG00000082068.4627.97710781.23300-0.315002.179101.46030K562TIA1
WDR70ENSG00000082068.4566.25500758.68300-0.422003.012002.01630K562TRIM56
WDR70ENSG00000082068.4489.51390747.75480-0.611204.619203.13380K562U2AF1
WDR70ENSG00000082068.4624.11810772.26800-0.307302.168901.45810K562U2AF2
WDR70ENSG00000082068.4515.32740729.90540-0.502203.741302.54030K562UCHL5
WDR70ENSG00000082068.41273.454701540.97930-0.275102.038901.31090K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR70 is not available on ENCORE database.





5 RBPs can affect the splicing of WDR70 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWDR70ENSG00000082068.4chr5+3770464437704727377030503770318937721216377251520.105000.000020.00080includedK562SRSF1
SEWDR70ENSG00000082068.4chr5+375166153751669237479935374800893760516537605340-0.082000.002130.03850excludedK562SF3B4
SEWDR70ENSG00000082068.4chr5+377229563772303637721159377213173772503537725152-0.148000.000000.00000excludedK562AQR
SEWDR70ENSG00000082068.4chr5+373964763739667237392101373922223743802337438083-0.066000.000140.00228excludedK562AQR
SEWDR70ENSG00000082068.4chr5+373795903737965637379313373794943738170337381787-0.060000.001020.01244excludedK562AQR
SEWDR70ENSG00000082068.4chr5+375166153751669237479935374800893760516537605340-0.108000.005330.04898excludedK562AQR
SEWDR70ENSG00000082068.4chr5+375166153751669237479935374800893760516537605340-0.105000.003720.08422excludedHepG2SF3A3
SEWDR70ENSG00000082068.4chr5+377229563772303637721216377213173772503537725152-0.060000.001290.04966excludedK562SF3B1
A3SSWDR70ENSG00000082068.4chr5+3738168037381787373817033738178737379590373796560.124000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR70 is not avaliable on ENCORE database.