TCF4

General Information

Gene Name       : TCF4
Gene ID             : ENSG00000196628.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: TCF4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TCF4ENSG00000196628.1617.7716.9817.38ENCSR000AEF
HepG2TCF4ENSG00000196628.160.000.000.00ENCSR985KAT
K562TCF4ENSG00000196628.167.7710.249.00ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TCF4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TCF4 RNA is bound by 11 proteins.  







eCLIP assay for TCF4 is not avaliable on ENCORE database.





11 proteins are bound to TCF4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr185313130653131369-3'-UTR,CDS,intron-Distal,intron-Proximal3.259364.44630K562ZNF622
chr185312828653128348-3'-UTR,CDS,intron-Distal,intron-Proximal5.142923.59565K562DDX24
chr185313130653131369-3'-UTR,CDS,intron-Distal,intron-Proximal3.954746.22817K562DDX24
chr185289086652890921-3'-UTR,intron-Distal5.714789.39648K562PABPC4
chr185292173052921837-CDS,intron-Distal,intron-Proximal3.442173.95301K562ZNF622
chr185293710252937188-CDS,intron-Distal,intron-Proximal5.239255.73530K562DDX24
chr185301743553017596-CDS,intron-Distal,intron-Proximal4.515646.27552K562KHSRP
chr185305324753053317-intron-Distal4.260974.78076K562HNRNPM
chr185325074353250813-intron-Distal4.109104.31512K562KHSRP
chr185292464852924797-intron-Distal,intron-Proximal4.046344.54401K562KHSRP
chr185324231953242432-intron-Distal4.352085.51743K562QKI
chr185306704353067138-intron-Distal5.294646.10540K562EIF4G2
chr185323387653233986-intron-Distal4.804836.01663K562MATR3
chr185320331453203407-intron-Distal3.512787.93121K562KHSRP
chr185323838353238620-intron-Distal3.080435.17040K562KHSRP
chr185319039553190477-intron-Distal3.827803.49011K562KHSRP
chr185325046753250605-intron-Distal4.9872414.81478K562HNRNPL
chr185325064853250743-intron-Distal3.410303.93901K562KHSRP
chr185303761753037722-intron-Distal4.986025.89856K562PTBP1
chr185320299553203048-intron-Distal4.172604.79379K562KHSRP
chr185322008753220152-intron-Distal3.696293.24603K562KHSRP
chr185305331753053416-intron-Distal3.457134.81774K562HNRNPM
chr185324247453242604-intron-Distal3.959323.49011K562KHSRP
chr185320696553207087-intron-Distal3.309544.72639K562KHSRP
chr185320971553209888-intron-Distal4.678887.00634K562KHSRP
chr185320349953203588-intron-Distal4.345625.68841K562KHSRP
chr185320358853203674-intron-Distal4.979468.57760K562KHSRP
chr185316452653164608-intron-Distal4.001244.31512K562KHSRP
chr185323201953232089-intron-Distal3.921873.14791K562HNRNPL
chr185323390853234027-intron-Distal4.153709.36870K562PTBP1
chr185322031753220421-intron-Distal3.152834.08064K562KHSRP
chr185305096753051013-intron-Distal3.542213.14999K562EXOSC5
chr185325236253252450-intron-Distal,intron-Proximal4.177038.41610K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TCF4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TCF4 is not available on ENCORE database.

  • 58 RBPs can affect the levels of TCF4.  








The Knockdown/knockout RNA-Seq assay for TCF4 is not available on ENCORE database.





58 RBPs can affect the gene expression of TCF4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TCF4ENSG00000196628.9685.23410833.06780-0.281802.214101.69700K562AGGF1
TCF4ENSG00000196628.9721.25350915.40060-0.343902.439801.52680K562AKAP8
TCF4ENSG00000196628.9643.37170866.84110-0.430103.358902.63810K562AKAP8L
TCF4ENSG00000196628.91435.37480879.543400.706508.221607.29790K562AQR
TCF4ENSG00000196628.9682.89690909.51810-0.413404.115802.98200K562ATP5C1
TCF4ENSG00000196628.9427.75030569.88560-0.413903.157702.13560K562BCLAF1
TCF4ENSG00000196628.91082.94310662.606200.708607.603806.12950K562BOP1
TCF4ENSG00000196628.9786.05970995.57370-0.340902.763601.58980K562CCDC124
TCF4ENSG00000196628.9935.87640704.310000.410003.417701.71950K562CEBPZ
TCF4ENSG00000196628.91702.08420822.300401.049509.073707.12400K562CNOT7
TCF4ENSG00000196628.91215.01390704.530300.7861012.1527010.50200K562CPSF6
TCF4ENSG00000196628.92048.368701353.002700.598209.695207.91570K562CELF1
TCF4ENSG00000196628.9732.09220977.41630-0.416903.222101.63740K562DDX19B
TCF4ENSG00000196628.91506.556201002.816000.5871011.203809.98950K562DDX47
TCF4ENSG00000196628.9776.66670504.547600.622205.510404.19500K562EFTUD2
TCF4ENSG00000196628.9460.84110303.607100.602002.607001.63340K562EIF3A
TCF4ENSG00000196628.9760.29880540.215900.492903.070101.97870K562EIF3D
TCF4ENSG00000196628.91525.550501100.411200.471207.228105.72220K562EIF4G2
TCF4ENSG00000196628.9563.70290403.929000.480702.886201.73430K562FKBP4
TCF4ENSG00000196628.91343.59640716.862600.9062013.2488011.31920K562FMR1
TCF4ENSG00000196628.91221.62290607.614401.0075014.0309011.83420K562FTO
TCF4ENSG00000196628.9684.81430505.842900.436902.741401.33110K562GEMIN5
TCF4ENSG00000196628.91229.17580672.644800.8697012.9962011.25390K562GPKOW
TCF4ENSG00000196628.9839.19620569.430000.559405.831404.30030K562HNRNPA1
TCF4ENSG00000196628.91226.69710769.664500.672404.333202.35190K562HNRNPAB
TCF4ENSG00000196628.9481.05360701.09530-0.543403.734402.64070K562HNRNPM
TCF4ENSG00000196628.91251.23850574.376301.1232013.0651010.90680K562KRR1
TCF4ENSG00000196628.9844.717601030.57230-0.286902.139201.35580K562MBNL1
TCF4ENSG00000196628.9965.19760656.579900.555805.641904.36270K562METAP2
TCF4ENSG00000196628.91037.45080667.670800.6357010.522009.05000K562MTPAP
TCF4ENSG00000196628.9919.69410741.906700.309803.151502.35910K562NSUN2
TCF4ENSG00000196628.91167.46040789.993200.563403.084601.77340K562PABPC1
TCF4ENSG00000196628.9510.16040664.11710-0.380502.807001.44860K562PCBP1
TCF4ENSG00000196628.91533.69750869.455600.818709.957308.38420K562PCBP3
TCF4ENSG00000196628.9449.50770623.93850-0.473102.988601.36680K562PKM
TCF4ENSG00000196628.91135.15120666.892300.7673011.9618010.35450K562POLR2G
TCF4ENSG00000196628.9655.48530967.61760-0.561904.999603.84340K562PPIG
TCF4ENSG00000196628.9713.84000490.982900.539803.961503.06510K562PRPF8
TCF4ENSG00000196628.91564.398501277.032500.292702.842301.75930K562PUM1
TCF4ENSG00000196628.91616.948101251.272300.369804.566003.32400K562PUM2
TCF4ENSG00000196628.9692.71580859.69490-0.311601.955301.48400K562PUS1
TCF4ENSG00000196628.9589.80980837.62130-0.506005.217204.42600K562RBM15
TCF4ENSG00000196628.9509.73230666.03380-0.385902.403201.39800K562NELFE
TCF4ENSG00000196628.91138.86250733.684500.634303.815701.94630K562RPS3A
TCF4ENSG00000196628.9708.11400502.008300.496202.687801.37820K562RRP9
TCF4ENSG00000196628.9833.28870614.369600.439603.296001.70440K562SDAD1
TCF4ENSG00000196628.91315.88280731.976600.846107.102605.84120K562SF3A3
TCF4ENSG00000196628.91405.13330639.738901.1351016.3094013.88720K562SF3B1
TCF4ENSG00000196628.9930.27740749.917100.310802.272601.41560K562SRPK2
TCF4ENSG00000196628.91012.42590722.584300.486505.562203.88840K562SRSF7
TCF4ENSG00000196628.9758.22890475.375400.673505.514504.04300K562SUPV3L1
TCF4ENSG00000196628.9484.56490631.71630-0.382602.642301.84340K562TIA1
TCF4ENSG00000196628.9656.75060807.75480-0.298602.505401.30400K562TROVE2
TCF4ENSG00000196628.9773.95840503.127400.621205.296103.84540K562UCHL5
TCF4ENSG00000196628.91024.37850673.123600.605704.037802.97430K562WDR3
TCF4ENSG00000196628.91190.77250699.913100.7666017.3620015.50490K562WDR43
TCF4ENSG00000196628.91359.259801042.290500.383003.580902.10090K562WRN
TCF4ENSG00000196628.91325.97190990.739500.420403.954502.89080K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TCF4 is not available on ENCORE database.





5 RBPs can affect the splicing of TCF4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
RITCF4ENSG00000196628.9chr18-5289607752899902528960775289630752899739528999020.257000.007530.04413includedK562PUS1
RITCF4ENSG00000196628.9chr18-5289607752899902528960775289630752899739528999020.279000.002800.03367includedK562PRPF8
RITCF4ENSG00000196628.9chr18-5289607752899902528960775289630752899739528999020.304000.000410.00592includedK562EFTUD2
RITCF4ENSG00000196628.9chr18-5289607752899902528960775289630752899739528999020.312000.001040.00697includedK562AQR
RITCF4ENSG00000196628.9chr18-528960775289990252896077528963075289975152899902-0.444000.004180.06498excludedK562PTBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TCF4 is not avaliable on ENCORE database.