SPI1

General Information

Gene Name       : SPI1
Gene ID             : ENSG00000066336.11
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: SPI1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878SPI1ENSG00000066336.110.845.963.40ENCSR000AEF
HepG2SPI1ENSG00000066336.110.110.000.06ENCSR985KAT
K562SPI1ENSG00000066336.1123.1610.7416.95ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for SPI1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • SPI1 RNA is bound by 16 proteins.  







eCLIP assay for SPI1 is not avaliable on ENCORE database.





16 proteins are bound to SPI1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr114738003947380082-3'-UTR,intron-Distal6.7012026.62028K562EIF4G2
chr114737982347379853-3'-UTR,intron-Distal4.144343.70058K562CSTF2T
chr114738008247380128-3'-UTR,intron-Distal5.6510021.09358K562EIF4G2
chr114737644247376503-3'-UTR,intron-Distal,intron-Proximal5.0653640.61021K562PUM2
chr114738002147380039-3'-UTR,intron-Distal7.6198726.43382K562EIF4G2
chr114737996747380024-3'-UTR,intron-Distal4.804476.56044K562IGF2BP1
chr114738001847380127-3'-UTR,intron-Distal6.864759.67573K562AATF
chr114737979247379845-3'-UTR,intron-Distal7.1983223.42536K562EIF4G2
chr114737985247379880-3'-UTR,intron-Distal6.3824610.49187K562EIF4G2
chr114738002447380079-3'-UTR,intron-Distal3.643028.44316K562IGF2BP1
chr114737997747380021-3'-UTR,intron-Distal6.5027924.64208K562EIF4G2
chr114737993847380008-3'-UTR,intron-Distal5.467166.84641K562DDX52
chr114737988047379914-3'-UTR,intron-Distal6.2928010.49187K562EIF4G2
chr114737997547380155-3'-UTR,CDS,intron-Distal6.7326626.23155K562TARDBP
chr114737681347376911-3'-UTR,CDS,intron-Distal3.496854.40383K562UCHL5
chr114738012247380203-3'-UTR,CDS,intron-Distal3.962784.23394K562TBRG4
chr114737979847379856-3'-UTR,intron-Distal3.846227.23433K562IGF2BP1
chr114738007947380132-3'-UTR,intron-Distal3.924466.55932K562IGF2BP1
chr114737991447379962-3'-UTR,intron-Distal6.4426011.47680K562EIF4G2
chr114738016447380239-CDS,intron-Distal5.735636.58215K562PHF6
chr114738018547380237-CDS,intron-Distal4.741886.67358K562IGF2BP1
chr114738015747380260-CDS,intron-Distal5.3430516.90120K562TARDBP
chr114738031147380359-CDS,intron-Distal,intron-Proximal5.4407313.86598K562EIF4G2
chr114738040647380472-CDS,intron-Distal4.2242515.11919K562EIF4G2
chr114738016747380255-CDS,intron-Distal7.4324124.92890K562EIF4G2
chr114738015447380243-CDS,intron-Distal3.879616.60399K562CSTF2T
chr114737709247377120-CDS,intron-Distal5.8168314.35031K562EIF4G2
chr114737948047379569-intron-Distal4.8826011.87937K562TARDBP
chr114737753747377625-intron-Distal4.7834010.52495K562TARDBP
chr114737757747377615-intron-Distal4.230174.86695K562IGF2BP1
chr114737823847378301-intron-Distal4.541926.44805K562IGF2BP1
chr114737964147379731-intron-Distal,intron-Proximal4.919438.37653K562IGF2BP1
chr114737746847377528-intron-Distal4.346534.71107K562CSTF2T
chr114737872847378889-intron-Distal5.0152013.73871K562TARDBP
chr114737939747379453-intron-Distal4.324313.98716K562IGF2BP1
chr114737842547378458-intron-Distal4.657219.87450K562EIF4G2
chr114739945847399491-intron-Distal4.834033.72755K562EIF4G2
chr114737962247379677-intron-Distal,intron-Proximal3.321164.25110K562CSTF2T
chr114737781847377928-intron-Distal5.100238.49227K562IGF2BP1
chr114737789147377929-intron-Distal6.8634713.94931K562EIF4G2
chr114737970447379727-intron-Distal,intron-Proximal5.785388.04355K562EIF4G2
chr114737721047377251-intron-Distal4.383573.34609K562TARDBP
chr114737903547379118-intron-Distal5.9298011.58578K562TARDBP
chr114737897147379035-intron-Distal5.8374211.05400K562TARDBP
chr114737713147377258-intron-Distal5.049058.39063K562DHX30
chr114737763747377700-intron-Distal7.7049927.93997K562EIF4G2
chr114737842547378562-intron-Distal4.5058510.51368K562IGF2BP1
chr114737835447378397-intron-Distal5.2242516.75815K562EIF4G2
chr114737883747378878-intron-Distal5.4384712.41769K562EIF4G2
chr114737727747377354-intron-Distal6.6662026.62028K562EIF4G2
chr114737717547377257-intron-Distal4.334426.90654K562GEMIN5
chr114737943547379525-intron-Distal5.7814311.64294K562AATF
chr114737834147378396-intron-Distal3.215143.93923K562DDX52
chr114737739247377483-intron-Distal7.5759128.44227K562EIF4G2
chr114737950947379656-intron-Distal,intron-Proximal4.224884.34791K562FUS
chr114737897747379044-intron-Distal3.425123.81856K562IGF2BP1
chr114737719347377283-intron-Distal6.2721611.20384K562PHF6
chr114737712047377188-intron-Distal7.5784826.93574K562EIF4G2
chr114737792947377980-intron-Distal7.2337120.92297K562EIF4G2
chr114737938547379447-intron-Distal3.792946.60399K562CSTF2T
chr114737757847377672-intron-Distal3.603954.47051K562EWSR1
chr114737743447377537-intron-Distal5.7385111.85065K562TARDBP
chr114737822347378273-intron-Distal6.9422317.42881K562EIF4G2
chr114737719747377254-intron-Distal5.1830014.73738K562AATF
chr114737950047379553-intron-Distal7.0367919.42400K562EIF4G2
chr114737718547377259-intron-Distal4.239273.86024K562EWSR1
chr114737948447379549-intron-Distal3.215145.62058K562CSTF2T
chr114737757747377616-intron-Distal5.344418.60100K562EIF4G2
chr114739236547392487-intron-Distal3.038105.44533K562HNRNPL
chr114737719447377294-intron-Distal3.9823310.19162K562CSTF2T
chr114738066847380735-intron-Distal3.869185.46600K562AKAP8L
chr114737758147377715-intron-Distal4.4900110.48798K562CSTF2T
chr114737938247379432-intron-Distal5.8812330.36552K562EIF4G2
chr114737941747379480-intron-Distal5.353968.89278K562TARDBP
chr114737718847377277-intron-Distal7.4568948.56239K562EIF4G2
chr114737845847378514-intron-Distal5.5237615.32498K562EIF4G2
chr114737813947378190-intron-Distal3.222463.99385K562CSTF2T
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for SPI1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for SPI1 is not available on ENCORE database.

  • 59 RBPs can affect the levels of SPI1.  








The Knockdown/knockout RNA-Seq assay for SPI1 is not available on ENCORE database.





59 RBPs can affect the gene expression of SPI1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
SPI1ENSG00000066336.7388.51300559.39060-0.525903.685402.22920K562APOBEC3C
SPI1ENSG00000066336.7261.13520354.59340-0.441402.169401.63870K562AQR
SPI1ENSG00000066336.7395.10440184.589201.0978012.6300010.54700K562BCLAF1
SPI1ENSG00000066336.7626.08140366.956100.770604.067502.27920K562BUD13
SPI1ENSG00000066336.7990.17970574.815200.784503.323101.72090K562CKAP4
SPI1ENSG00000066336.71698.34290641.345701.404902.682001.64170K562CNOT7
SPI1ENSG00000066336.71053.76480580.249500.860709.142707.69810K562CPSF6
SPI1ENSG00000066336.7309.62940140.038401.1446010.059707.87100K562CSTF2
SPI1ENSG00000066336.7701.13430514.455200.446504.091702.60040K562DDX21
SPI1ENSG00000066336.7229.40950161.898500.502702.676801.38210K562DDX27
SPI1ENSG00000066336.7399.79260275.381900.537704.000302.34020K562DDX6
SPI1ENSG00000066336.7737.00620404.495900.865505.207903.27090K562DHX30
SPI1ENSG00000066336.7564.45670162.947401.7924025.5777022.38340K562EFTUD2
SPI1ENSG00000066336.7484.63980257.555300.911906.896205.83550K562EIF2S2
SPI1ENSG00000066336.7441.24780633.99280-0.522904.630903.42830K562EIF4G2
SPI1ENSG00000066336.7800.36780282.190801.5039030.3795026.59370K562EXOSC5
SPI1ENSG00000066336.71077.55630590.470700.867704.721703.60220K562FMR1
SPI1ENSG00000066336.7769.97360500.512100.621305.046703.76930K562FTO
SPI1ENSG00000066336.7113.53900295.11050-1.3781013.7819012.53610K562FXR1
SPI1ENSG00000066336.732.2260075.61140-1.230402.727002.02650K562G3BP2
SPI1ENSG00000066336.7330.39020163.377601.015903.525101.88550K562GEMIN5
SPI1ENSG00000066336.71144.38080553.962201.0466017.4016015.34750K562GPKOW
SPI1ENSG00000066336.7502.97500390.905700.363601.963201.44930K562HNRNPC
SPI1ENSG00000066336.7759.57900514.665300.561503.943301.71950K562IGF2BP1
SPI1ENSG00000066336.7664.26310473.101900.489502.131801.32420K562KRR1
SPI1ENSG00000066336.7544.56800348.735500.642905.253603.05640K562LSM11
SPI1ENSG00000066336.7981.55690540.743000.860005.601404.32920K562METAP2
SPI1ENSG00000066336.7439.86840606.25260-0.462802.238901.46600K562NAA15
SPI1ENSG00000066336.7366.69420160.838801.188904.691602.87570K562NONO
SPI1ENSG00000066336.7929.09710642.442400.532208.183806.99690K562NSUN2
SPI1ENSG00000066336.7554.31450384.998200.525803.296301.68890K562NUSAP1
SPI1ENSG00000066336.7227.89980128.049600.831604.460003.21020K562PCBP2
SPI1ENSG00000066336.7575.91780429.851300.421902.532701.75280K562PPIG
SPI1ENSG00000066336.7217.01420423.91610-0.966005.137102.65800K562PRPF6
SPI1ENSG00000066336.7662.18490350.508600.917707.394405.77950K562PSIP1
SPI1ENSG00000066336.7395.91660691.70520-0.805004.183503.18680K562PUF60
SPI1ENSG00000066336.7585.91210735.94110-0.328902.468401.46420K562PUM1
SPI1ENSG00000066336.7979.87040720.868200.442804.052702.88520K562PUM2
SPI1ENSG00000066336.7282.05390134.037501.073204.973703.80750K562RBM22
SPI1ENSG00000066336.7122.0903071.639700.769002.789301.45560K562RBM25
SPI1ENSG00000066336.7828.19170526.959000.652205.174103.82130K562SF3B1
SPI1ENSG00000066336.7453.85380303.239900.581703.767202.51690K562SRFBP1
SPI1ENSG00000066336.7307.43930158.453100.956104.522602.37890K562SRP68
SPI1ENSG00000066336.7496.94170649.42620-0.386102.918401.96070K562SRPK2
SPI1ENSG00000066336.7454.52630137.122601.7288016.3888014.67490K562SRSF1
SPI1ENSG00000066336.7452.16640229.246000.979903.495802.29320K562SRSF4
SPI1ENSG00000066336.7259.86180129.537701.004307.144505.34290K562SRSF5
SPI1ENSG00000066336.7597.16080459.083700.379303.044501.81230K562SRSF7
SPI1ENSG00000066336.7318.06430496.89340-0.643604.698302.87540K562SSRP1
SPI1ENSG00000066336.7327.02720153.379801.092202.642901.65020K562SUPV3L1
SPI1ENSG00000066336.7153.64390276.16420-0.845903.544402.61450K562SYNCRIP
SPI1ENSG00000066336.7241.53970133.844200.851605.005803.85410K562TIA1
SPI1ENSG00000066336.7239.85290131.414700.867903.517802.25740K562TRA2A
SPI1ENSG00000066336.735.2433073.20890-1.054702.675201.60330K562U2AF1
SPI1ENSG00000066336.7415.34160162.408601.3546011.095209.01150K562UCHL5
SPI1ENSG00000066336.71060.88150681.193200.6390010.728109.43060K562UPF1
SPI1ENSG00000066336.7398.70290551.38540-0.467702.849901.62850K562UTP3
SPI1ENSG00000066336.7311.05820606.10220-0.9624016.0169014.21340K562WDR43
SPI1ENSG00000066336.7438.71130165.495601.4064014.6475011.60740K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for SPI1 is not available on ENCORE database.





5 RBPs can affect the splicing of SPI1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESPI1ENSG00000066336.7chr11-473971834739728347381403473815914739985947399942-0.058000.000030.00080excludedK562PUS1
SESPI1ENSG00000066336.7chr11-473971834739728047381403473815914739985947400038-0.058000.000010.00063excludedK562RBM15
SESPI1ENSG00000066336.7chr11-473971834739728347381403473815914739985947399942-0.056000.000140.00598excludedK562AGGF1
A3SSSPI1ENSG00000066336.7chr11-4738039447380615473803944738055747381403473815910.057000.003690.02213longerK562AQR
MXESPI1ENSG00000066336.7chr11-47381403473815914739718347397280473803944738055747399859474001270.287000.000030.002631includedK562FXR2
MXESPI1ENSG00000066336.7chr11-47381403473815914739718347397283473803944738055747399859473999420.181000.002440.049211includedK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for SPI1 is not avaliable on ENCORE database.